과민성 대장 증후군 환자에서 Colpermin 투여의 임상 효과

금민수,조창민,김대현,이창형,권영오,김성국,최용환,정준모 慶北大學校 醫科大學 1997 慶北醫大誌 Vol.38 No.1

목적 : 과민성 대장 증후군은 장기능 이상의 증상군으로, 인지할 수 있는 기질적 위장관 병태 생리가 없는 경우로 기능적인 장관의 이상 경축과 가장 밀접한 관련이 있을 것으로 생각된다. 그러나 치료면에서는 아직 뚜렷한 방침이 정립되어 있지 않고 다양한 방법들이 제시되고 있는 실정이다. 저자들은 장용성 캅셀로 조제된 박하유 성분인 Colpermin® 의 임상 효과를 평가하고자 본 연구를 시행하였다. 대상 및 방법 : 1996년 2월부터 1996년 11월까지 경북대학교병원 소화기 내과를 방문하여 과민성대장 증후군으로 진단된 34명의 환자를 대상으로 Colpermin® 을 1회 2캅셀씩, 1일 3회, 경구로 2주간 투여하였다. 결과 : 투여전의 증상의 빈도는 복통 88.2%(30/34) 및 설사 73.5%(25/34)를 호소하는 경우가 가장 많았으며, 그 다음으로 변비 50.0%(17/34), 복부 팽만 47.1%(16/34), 고창 38.2%(13/34)순이었다. 약물 투여후 증상별 개선율은 설사를 보였던 환자들에서 호전 11예와 매우 호전 11예로 88.0%(22/25)의 가장 높은 개선율을 보였고, 그 다음으로 복통 73.3%(22/30), 고창 69.2%(9/13), 변비 64.7%(11/17), 복부 팽만 56.3%(9/16)의 순이었다. 종합적인 증상의 개선도는 현저한 개선이 2예(5.9%), 중등도 개선이 9예(26.5%), 약간 개선이 18예(52.9%), 불변이 4예(11.8%), 악화가 1예(2.9%)였으며, 종합적인 유효율은 85.3%(29/34)였다. 약물의 부작용으로 3예의 환자에서 각각 복부 팽만의 발생, 변비의 악화, 복통의 발생이 있었으나, 그 외의 환자들에서는 아무런 부작용도 관찰되지 않았다. 결론 : 과민성 대장 증후군의 약물치료에 있어서 Colpermin®이 유용한 약제가 될 수 있을 것으로 기대된다. Irritable bowel syndrome (IBS) is a disease characterized by a collection of symptoms of intestinal dysfunctions, without any recognized organic gastrointestinal pathology. This study was performed to evaluate clinical effectiveness of peppermint oil (Colpermin®) in the treatment of patients with IBS. 34 patients (18 males and 16 females) with IBS were treated with peppermint oil 0.4ml (as menthol 176㎎) three times daily for 2 weeks and the efficacy of the treatment was evaluated according to the degree of the improvement. The improvement of symptoms was 88.0% (22/25) in diarrhea, 73.3% (22/30) in abdominal pain, 69.2% (9/13) in flatulence, 64.7% (11/17) in constipation, and 56.3% (9/16) in abdominal distension, respectively. Overall effectiveness of subjective symptoms was 85.3% (29/34). Side effects of the drug were noted in only 3 cases, those were aggravation of constipation, development of abdominal distension and abdominal pain. As a result, Colpermin® might be considered as an effective drug in relieving symptoms of IBS.

冬蟲夏草 첨가에 따른 증편의 품질 특성

박금순,박찬성,최미애,김정숙,조현정 한국조리과학회 2003 한국식품조리과학회지 Vol.19 No.3

전통중편의 단백영양 보강을 위하여 동충하초를 첨가하여 중편의 이화학적, 기계적, 관능적 품질특성을 조사하였다. 동충하초 첨가량을 달리한 중편의 부피는 동충하초 첨가군이 대조군에 비해 증가하였고 pH는 동충하초 5%첨가 중편이 가장 낮게 나타났다. 수분은 대조군에 비해 첨가군의 수분 함량이 낮았고(p<0.01) 동충하초 첨가군 사이에 유의적인 차이는 없었다. 아미노산 함량은 대조군보다 동충하초 첨가군이 높았으며 필수아미노산을 골고루 함유하고 특히 Leucine, Phenylalanine, Arginine이 높았다. 동충하초첨가 중편의 texture변화에서 색도 중 L값은 대조군에 비해 동충하초 첨가량이 증가할수록 감소하였으며 반면에 a, b값은 첨가량이 증가할수록 증가하였다. texture 측정에서는 껌성은 5% 첨가군이 낮게 나타났고, brittlenes는 7% 첨가군이 대조군과 다른 첨가군중에서 가장 높게 나타났다. 관능검사에서 texture에서는 응집성이 5% 첨가군, 탄력성은 3% 첨가군이 가장 높게 평가되었으나 유의적인 차이는 없었다. flavor에서 stale grain flavor과 bitterness는 동충하초 첨가량을 증가시킬수록 높게 나타나는 경향을 보였다. 이상의 결과에서 동충하초 중편의 제조에서 이화학적 특성, 기계적 특성, 관능적 특성을 종합했을 때 동충하초 농도를 3%, 5% 첨가시 최적농도임을 도출해 내고 품질이 향상됨을 확인할 수 있었다. higher The Hunter color test showed lower L values with higher amounts of added JP to the Jeung-Pyun. In the sensory test, the 7% added group had the strongest color according to the texture; the highest cohesiveness was shown in the 5% added group. and the highest springiness was shown by the 3% added group, but none of these showed any significant differences. As for flavor, the more JP added the higher the stale grain flavor and bitterness. In the result of the overall acceptability test, the stale grain flavor of the 5% added group showed the highest values for the favorite texture and flavor. From the results of this experiment, when making stale grain flavored Jeung-Pyun, the 3 and 5% added groups were the optimum concentrations for the observed improvements in the quality. This study was carried out to investigate the possibility of improving the quality characteristics of Jeung-Pyun, by the addition of Paecilomyces japonica powder (JP). Regarding the volume of the Jeung-Pyun fermentation, with respect to the different amounts of JP added, the groups containing JP showed increased volumes, and as for the pH, the group containing 5% showed the lowest value. Regarding the moisture content, the groups containing JP showed lower moisture contents than the control group. Regarding the amino acid content, the control group showed a higher amino acid content than those of the JP containing groups, and contained an even amount of essential amino acids, and Leucine, Phenylalanine and Arginine were especially

눈꽃동충하초(Paecilomyces japonica)를 첨가한 증편의 미생물학적 품질특성 및 저장성

박찬성,최미애,박금순 한국조리과학회 2004 한국식품조리과학회지 Vol.20 No.6

The purpose of this study was to investigate the effect of Paecilomyces japonica mycelia(PJM) on pH, titrable acidity and microbiological quality of Jeungpyun(fermented rice cake). Jeungpyun prepared with 0?7% of PJM stored at 5℃ and 20℃ for 4 weeks and 7 days respectively. Before fermentation of Jeungpyun dough, viable cells of total bacterial counts(TBC), yeasts and lactic acid bacteria(LAB) were 6.0~9.8×10^6, 5.3~9.0×10^(6), 5.4~8.5×10^(6) CFU/g, respectively. During the fermentation of dough, viable cells of TBC, yeasts and LAB increased 0.3~0.4 log cycle and pH was decreased whereas acidity incresed as the progress of fermentation. Total viable cells in Jeungpyun before storage were 5.0×10¹ CFU/g. During storage of Jeungpyun, TBC, yeasts and LAB of control group increased 2.6, 2.4, 2.1 log cycle at 5℃ and 4.8, 4.6, 4.5 log cycle at 20℃, respectively, when reached at maximum level. Major microflora of Jeungpyun was composed of yeasts and LAB during fermentation of dough and storage at 5℃ and 20℃. Addition of PJM, inhibited the growth of microorganisms, the changes of pH and titrable acidity of Jeungpyun during storage at both of 5℃ and 20℃. From these results, the addition of PJM extended the shelf-life of Jeungpyun during storage at 5℃ and 20℃.

정신분열증 환자의 MMPI

이금단,오상우 圓光大學校 醫科學硏究所 2001 圓光醫科學 Vol.16 No.1-2

배경 : MMPI는 임상장면에서 가장 유용한 진단도구 중의 하나로 알려져 왔다. 본 연구에서는 정신과에 입원하고 있는 정신분열증 환자들의 MMPI 프로파일이 어떤 유형들로 분류되는 지를 알아보고, 이에 따라 분류된 MMPI 프로파일 유형을 토대로 분할점을 제시하고자 하였으며, 각 프로파일 유형에 따른 내용척도, 인구통계학적 특징 및 증상들을 살펴보았다. 방법 : 본 연구의 대상은 1998년 1월부터 2000년 8월까지 원광대학교병원 신경정신과에 입원하여 임상심리검사에 의뢰된 환자들 중 임상심리전문가와 정신과 주치의에 의해 정신분열증으로 진단된 환자 61명으로 남자 37명, 여자 24명으로, 이들의 MMPI와 정신분열증 프로토콜 자료를 수집하여 분석 하였다. 결과 : 정신분열증으로 입원한 환자들을 대상으로 하여 MMPI 상에서 분할점을 T점수 65점으로 잡았을 때 이들은 F-6은 유형을 보였고, 군집분석결과, 잠재성 정신분열증 유형, 편집형 정신분열증 유형 및 정상 유형이 확인되었다. 의뢰사유에 있어서는 불안/신경예민, 짜증, 과대망상에서만 각 군집간에 차이를 보였다. 결론 : 입원한 정신과 환자 중 MMPI의 F-6-8 척도치가 T점수 65점 이상을 보이는 경우에는 정신분열증으로 진단을 내릴 수 있음이 확인되었다. 그렇지만 정신분열증 환자 집단은 동질적인 특성을 지닌 집단이 아니라 이질적인 특성을 지닌 집단이므로 이들에 대한 치료와 재활을 제대로 수행하기 위해서는 환자의 개별적인 정신병리와 성격특성을 우선 파악하는 것이 중요하다. Background : The MMPI has known one of the most powerful diagnostic tools in clinical setting. This study was to identify the distinct MMPI profile, the cut-off score and chief complaints in inpatients with schizophrenia. Methods : 61 patients with schizophrenia (male 37, female 24) administered the MMPI and Symptom Check Lists were collected by the authors. Results : The MMPI profile of patients with schizophrenia showed F-6-8 profile and 65 T was identified as the cut-off score. K-mean cluster analysis showed three sub-clusters, which were latent schizophrenia profile, paranoid schizophrenia profile and normal profile. And only a few chief complaints were found the differences among sub-clusters. Conclusion : This study concluded that elevations above 65 T in F-6-8 profile could be diagnosed as schizophrenia. However, patients with schizophrenia are not homogeneous but heterogeneous. Thus, it is suggested that their individual psychopathology and psychological characteristics should be examined prior to therapy or rehabilitation.

우리나라 환경정책의 변화과정에서 나타난 문제점과 발전방향

홍금우,정성윤 조선대학교 통일문제연구소 2003 統一 問題 硏究 Vol.16 No.-

자기진단형 위상제어에 의한 단상유도전동기의 특성 및 모니터링 시스템에 관한 연구

조금배,박수강,백형래,임양수,이성길 조선대학교 에너지.자원신기술연구소 2003 에너지·자원신기술연구소 논문지 Vol.25 No.2

The three-phase induction motor is rugged, reliable, long-lived, self-starting, smooth-running. But it is relatively inexpensive and three-phase power in not available everywhere, so if possible we need single-phase motor with the same characteristics. In fact, single-phase induction motors have excellent characteristics and outnumber the three-phase variety. Most of the small electric motors used in home, farm, or office are single-phase induction motors of one type or another. This electric motors application field need most energy saving type drive according to enlargement of electronic goods and to tend high class. The paper is proposed a various phase control methods for energy saving of single- phase induction motor. The controllers that are embodied by each method can use by various usage according to each performance and it is considered that application may help in the electrical energy saving because is possible to other electrical appliances.

전분 종류를 달리한 살구편의 품질 특성

박금순,권진희,허성미 동아시아식생활학회 1999 동아시아식생활학회지 Vol.9 No.4

This study was conducted in order to investigate the quality characteristics of Salku Pyun which was made by using mungbean, potato, sweet potato and corn starches. The pH of salku juice was 3.45 to 3.50 and the brix of that was 7.0%. The water content and water activity of salku pyun with potato starch was highest, The result of sensory evaluation showed that appearance, flavor, overall quality were highest in the Salku Pyun made with potato starch while texture, taste were highest in the Salku Pyun made with mungbean starch. Mechanical properties of salku pyun with mungbean starch was significantly higher in adhesiveness, hardness, chewiness. Texture of sensory evaluation were positively correlated with springiness, hardness, and chewiness of mechanical measurement, The factors which affect the overall quality on sensory evaluation were texture quality, taste quality, hardness, color and springiness.

유해화학물질의 계통분석

박성우,박유신,이진훈,유재훈,김유나,오세진,이진숙,김남이,박종신,남금문,노동석 內務部 國立科學搜査硏究所 2002 國立 科學 搜査 硏究所 年報 Vol.34 No.-

韓國産 납자루 亞科 魚類의 染色體와 ARM NUMBER

李金泳,蘇俊魯,金聖周 全北大學校 基礎科學硏究所 1982 基礎科學 Vol.5 No.1

Karyotypes of 12 species of the Acheilognathine fishes were studied using chromosomes of gill slit and kidney cells prepared by the flame drying technique. The results were as follows : 1. Numbers of chromosomes were classified into three patterns as 2n=48, 44, and 46. 2. In the 2n=48, No. of two-arm chromosome (TAC) and one-arm chromosome (OAC)were 12 or 14 pairs and 10 or 12 pairs, respectively. In the 2n=44, TAC and OAC were 14 or 12 and 8 or 10, severally, In the 2n=46, TAC was 2 pairs and OAC was 21 pairs. 3. Above results indicate that patterns of arm number(AN) were classified into four groups as AN=76, 72, 68, and 50. In the view of these results, we suggest that primitive chromosomal type of Acheilognathine fishes(cyprinidae) was 2n=46 and AN=50(R. notatus, R. suigensis).

우리나라 환경영향평가제도의 문제점과 개선방향

홍금우,정성윤 朝鮮大學校 2003 經營經濟硏究 = Management and economics research Vol.26 No.1

This research is to point out problems and improvements about the present system of environmental impact assessment in Korea. Environmental impact assessment is an integral part of a decision-making process for a development project. But There are some problems in this system. So this paper presents a number of policy alternatives which environmental impact assessment can be improved First, an Environmental Impact assessment report should be prepared by the fair and objective person not developer. Second, Environmental Impact assessment system is not enough, so screening system and seeping system should be added to it. It need to reinvented so as to include a practical alternative investigation. Third, comprehensive environmental information system on the regional and national levels should be established ton provide necessary information prior to Environmental Impact Assessment. Fourth, Environmental Impact assessment time and participation of regional residents is not enough.