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      • SCISCIESCOPUS

        Significance of Genetic, Environmental, and Pre- and Postharvest Factors Affecting Carotenoid Contents in Crops: A Review

        Saini, Ramesh Kumar,Keum, Young-Soo American Chemical Society 2018 Journal of agricultural and food chemistry Vol.66 No.21

        <P>Carotenoids are a diverse group of tetraterpenoid pigments that play indispensable roles in plants and animals. The biosynthesis of carotenoids in plants is strictly regulated at the transcriptional and post-transcriptional levels in accordance with inherited genetic signals and developmental requirements and in response to external environmental stimulants. The alteration in the biosynthesis of carotenoids under the influence of external environmental stimulants, such as high light, drought, salinity, and chilling stresses, has been shown to significantly influence the nutritional value of crop plants. In addition to these stimulants, several pre- and postharvesting cultivation practices significantly influence carotenoid compositions and contents. Thus, this review discusses how various environmental stimulants and pre- and postharvesting factors can be positively modulated for the enhanced biosynthesis and accumulation of carotenoids in the edible parts of crop plants, such as the leaves, roots, tubers, flowers, fruit, and seeds. In addition, future research directions in this context are identified.</P> [FIG OMISSION]</BR>

      • KCI등재

        Temporary love: A love-hate transition among luxury fashion consumers in a mediation of brand jealousy and moderation of value-expressiveness

        Saini Aarti,Kashif Muhammad,Platania Silvia 한국마케팅과학회 2023 마케팅과학연구 Vol.33 No.4

        There is a limited amount of research to investigate emotional transition (i.e. love to hate) among consumers. Moreover, can valueexpressiveness motivate consumers to not to share negative word of mouth (NWOM) despite hating a brand? This study aims at addressing these important research questions. Survey-based data is collected from 413 Indian luxury fashion consumers and analyzed via structural equation modelling technique, using AMOS 27.0. Findings reveal that brand jealousy mediates the relationship between brand love and brand hate. Furthermore, when value expressiveness is low, the relationship between brand hate and negative word of mouth is stronger. Brand marketers should strengthen symbolic brand identity to sustain positive consumerbrand emotions. Moreover, some relationship dyads can be used to establish the brand image in a family-oriented, collectivist culture. The mediation of brand jealousy and the moderation of NWOM are unique contributions of this study in an Indian context.

      • KCI등재SCIESCOPUS

        Electrical characterization of <i>a</i>-axis oriented Y123 thin film grown using pulsed laser deposition

        Saini, S.,Takamura, M.,Mukaida, M.,Kim, S.-J. Elsevier 2011 CURRENT APPLIED PHYSICS Vol.11 No.5

        <P><B>Abstract</B></P><P>The thin film of <I>a</I>-axis oriented YBa<SUB>2</SUB>Cu<SUB>3</SUB>O<SUB>7</SUB> (Y123) were grown on SrLaGaO<SUB>4</SUB> (100) substrate with a buffer layer of 50 nm thick Gd<SUB>2</SUB>CuO<SUB>4</SUB> using pulsed laser deposition technique. The thickness of Y123 thin film is about 400 nm CuO<SUB>2</SUB> planes are aligned perpendicular to the substrate in the thin films. A micron-bridge was fabricated using focused ion beam milling technique in such a way that the current was forced to flow along the <I>c</I>-axis in thin film. Intrinsic Josephson junctions are aligned along the <I>c</I>-axis. The dimensions of bridge are 1 μm in length along the <I>c</I>-axis and 5 μm in width along the <I>b</I>-axis. Transition temperature (<I>T<SUB>cON</SUB></I>) is about 84 K with single phase. The critical current density (<I>J<SUB>c</SUB></I>) of 2 × 10<SUP>6</SUP> A/cm<SUP>2</SUP> was measured from current–voltage (<I>I–V</I>) characteristics at 10 K. The samples were irradiated with external microwave of 20 GHz at different power and the <I>J<SUB>c</SUB></I> was suppressed as we increased the power. This suppression in <I>J<SUB>c</SUB></I> indicates the formation of layered structure with strong coupling. The voltage steps are appeared in non-linear <I>I–V</I> characteristics with microwave irradiation. The voltage steps are collective response of intrinsic Josephson junctions of micron-bridge.</P>

      • KCI등재

        Incidence of Renal Tract Abnormalities on Ultrasonography in Patients with Spinal Cord Injury: A Retrospective Pilot Study of a Military Cohort Undergoing Long-Term Institutional Rehabilitation

        Saini Mandeep,Kataruka Mohit,Gogoi Biraj,Sharma Vyom,Madan Gurdarshdeep Singh,Sood Chetan 대한척추외과학회 2022 Asian Spine Journal Vol.16 No.2

        Study Design: Retrospective pilot study. Purpose: To assess the incidence of renal tract abnormalities using ultrasonography (US) in a military cohort with traumatic spinal cord injury (TSCI) at a tertiary level spinal cord injury center. Overview of Literature: Neurogenic bladder in TSCI patients results in significant urological morbidity. There is lack of data for these patients during the first 18 months of long-term rehabilitation in an institutional setting. Methods: We retrospectively reviewed patient records to collect data on demographic characteristics, injury level, injury severity, time since injury, bladder management methods (such as an indwelling catheter [IC], clean intermittent catheterization [CIC], or self-voiding [S]); we correlated these data with the findings of the renal tract US. Results: The study included 73 out of 81 male participants. The mean patient age was 29.99 years; the study group included 34.2% tetraplegics and 65.8% people with paraplegia. The time since injury was 6–12 months for 42.5% of the subjects and 12–18 months for 57.5% of the subjects. A normal US scan was recorded in 65.7% patients, and bladder trabeculation was the commonest finding in 15.1% of the subjects, followed by hydronephrosis (HDN) in 12.3%, and renal calculus and atrophy in 1.3% participants each. We found 22.22% of the IC group participants had higher US abnormalities than those in the reflex voiding group (statistically non-significant difference, p=0.7). Trabeculations (21.4%) and HDN (19%) were more common in those who had sustained the injury 12–18 months previously as compared to that in those who had injured themselves 6–12 months previously (p=0.04). The proportion of patients who had a normal US scan was higher in the group who sustained the injury 6–12 months previously versus those who had sustained the injury 12–18 months previously; the difference was statistically significant (p=0.02). There was no significant (p=0.72) correlation in the bladder management method, injury level, and renal tract abnormalities between the groups. Conclusions: This retrospective study shows that 65% of TSCI participants had no renal tract abnormality on US scan and bladder trabeculation ruled out as the most common finding. Long-term supervised rehabilitation may help achieve good renal quality of life; however, further prospective trials are required on this subject.

      • Microwave Dependence of <tex> $a$</tex>-Axis Oriented <tex> ${\rm YBa}_{2}{\rm Cu}_{3}{\rm O}_{7}$</tex> Thin Film

        Saini, S,Takamura, M,Mukaida, M,Kim, S.-J IEEE 2011 IEEE transactions on applied superconductivity Vol.21 No.3

        <P>The <I>a</I>-axis oriented YBa<SUB>2</SUB>Cu<SUB>3</SUB>O<SUB>7</SUB> thin films were grown on SrLaGaO<SUB>4</SUB> (100) substrate with a buffer layer of 50 nm thick Gd<SUB>2</SUB>CuO<SUB>4</SUB> using pulsed laser deposition technique. The thickness of Y-123 thin film was about 500 nm. Intrinsic Josephson junctions (CuO<SUB>2</SUB> planes) were aligned perpendicular to the substrate in the thin films. The bridge type pattern was fabricated using focused ion beam milling technique in such a way so that the current flow along the <I>c</I> -axis in thin film. The dimensions of bridge were 1 μm in length along the <I>c</I>-axis and 5 μm in width along the b-axis. The resistance vs. temperature characteristics showed transition temperature of about 89 K. The critical current density (J<SUB>c</SUB>) of 2×10<SUP>6</SUP> A/cm<SUP>2</SUP> was measured from current-voltage (I-V) characteristics at 10 K. The samples were irradiated with external microwave at 20 GHz and the J<SUB>c</SUB> was suppressed with increase in power. This suppression in J<SUB>c</SUB> indicates the formation of layered structure with strong coupling. The voltage steps were appeared with microwave irradiation in I-V characteristics. The values of voltage steps were irregular and change with increase in power. We have also studied all <I>a</I>-axis oriented multilayered thin films of YBa<SUB>2</SUB>Cu<SUB>3</SUB>O<SUB>7</SUB> (Y123) and PrBa<SUB>2</SUB>Cu<SUB>3</SUB>O<SUB>7</SUB> (Pr123). We fabricated a submicron stack in which Josephson junctions were forming by Y123 and Pr123. The submicron stack showed response with microwave irradiation of different frequency and power. The transport characteristics of these thin films are discussed in detail.</P>

      • SCISCIESCOPUS

        An efficient one-step scheme for the purification of major xanthophyll carotenoids from lettuce, and assessment of their comparative anticancer potential

        Saini, Ramesh Kumar,Moon, So Hyun,Gansukh, Enkhtaivan,Keum, Young-Soo Elsevier 2018 Food chemistry Vol.266 No.-

        <P><B>Abstract</B></P> <P>The foremost problem in carotenoid research is the excessive cost and difficulty of maintaining pure carotenoid compounds. This work presents an economical, efficient, and simplified one-step scheme for the purification of four major xanthophyll carotenoids from lettuce by utilizing preparative thin layer chromatography on Hyflo-Super-Cel: MgO (Heavy): calcium sulfate hemihydrate (9:9:2 w/w) based adsorbent. The mobile phase of acetone: hexane (1:1) provided the perfect separation of major xanthophylls, resulting in 95–96% purity after just single-step separation, with no interference from chlorophylls or other minor carotenoids. The identity of carotenoids was confirmed by absorption spectroscopy, chemical tests and APCI<SUP>+</SUP>–MS/MS. The proposed scheme can be used to isolate the carotenoids at the analytical and preparative scale. In anticancer studies, among four xanthophylls, 9-<I>Z</I>-neoxanthin was found most potent for reduction of cell viability of cervical (HeLa) and lung cancer (A549) cells, with IC<SUB>50</SUB> values of 3.8 and 7.5 μM, respectively.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Hyflo-Super-Cel: MgO: calcium sulfate hemihydrate based adsorbent was used. </LI> <LI> The mobile phase of acetone: hexane (1:1) provided the perfect separation. </LI> <LI> Utilizing proposed scheme carotenoids can be isolated with 95–96% purity. </LI> <LI> 9-<I>Z</I>-neoxanthin is the most potent inhibitor of HeLa and A549 cells proliferation. </LI> </UL> </P>

      • Omega-3 and omega-6 polyunsaturated fatty acids: Dietary sources, metabolism, and significance — A review

        Saini, Ramesh Kumar,Keum, Young-Soo Elsevier 2018 Life sciences Vol.203 No.-

        <P><B>Abstract</B></P> <P>Linoleic acid (LA) (n−6) and α-linolenic acid (ALA) (n−3) are essential fatty acids (EFAs) as they cannot be synthesized by humans or other higher animals. In the human body, these fatty acids (FAs) give rise to arachidonic acid (ARA, n−6), eicosapentaenoic acid (EPA, n−3), and docosahexaenoic acid (DHA, n−3) that play key roles in regulating body homeostasis. Locally acting bioactive signaling lipids called eicosanoids derived from these FAs also regulate diverse homeostatic processes. In general, ARA gives rise to pro-inflammatory eicosanoids whereas EPA and DHA give rise to anti-inflammatory eicosanoids. Thus, a proportionally higher consumption of n−3 PUFAs can protect us against inflammatory diseases, cancer, cardiovascular diseases, and other chronic diseases. The present review summarizes major sources, intake, and global consumption of n−3 and n−6 PUFAs. Their metabolism to biosynthesize long-chain PUFAs and eicosanoids and their roles in brain metabolism, cardiovascular disease, obesity, cancer, and bone health are also discussed.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

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