http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
( Sae Byeol Chol ),( Kyung Sik Kim ),( Dong Sub Yoon ),( Kwang Hyub Han ),( Woo Jung Lee ),( Byong Ro Kim ),( Jin Sil Seong ),( Jong Tae Lee ) 대한소화기학회 2007 SIDDS Vol.9 No.-
Background/Aims: In cases of advanced hepatocellular carcinoma (HCC), palliative treatment such as transarterial chemoembolization or chemoinfusion (TACE/TACI) and radiation therapy are performed preoperatively. The aim of this study was to evaluate the outcome of these preoperative treatment prior to hepatic resection. Methods: Between January 1994 and May 2007, 16 patients with advanced stage HCC greater than 5 cm in size are treated with TACE/TACI and radiation therapy prior to hepatic resection. The clinicopathologic factors were reviewed retrospectively. Results: Of the sixteen patients, there were fourteen men and two women, and the mean age was 51 years (range 22-70 years). Preoperative TACE/TACI was performed three times in average, and the median radiation dosage was 45 Gy (range 30-68 Gy). Major hepatic resection was performed. The median diameter of tumor on specimen was 9.0 cm. The degree of tumor necrosis was more than 90% in fourteen patients. Median survival time was 13.3 months. Eleven patients were dead due to tumor recurrence (n=8) and hepatic failure (n=2). Five patients had survived more than 2 years and there were two patients who had survived more than 5 years. Conclusions: Although the prognosis of HCC patients who were underwent preoperative combined TACE/TACI and radiation therapy is not satisfactory, some showed long term survival more than 5 years. Further research will be required to examine the survival and disease control impact in a prospective randomized study.
Clinical Decision of Surgical Management: Benign Lesions
( Sae Byeol Choi ) 대한간학회 2019 Postgraduate Courses (PG) Vol.2019 No.1
Benign liver tumors are a heterogeneous group of lesions with different cellular origins. These lesions are often found incidentally due to widespread use of imaging studies and usually have a benign course. Traditionally the management of benign hepatic tumors has been conservative. With increased need of diagnostic imaging studies and improvement in their resolution, detection of liver lesions has increased. Benign liver tumors are categorized as solid tumor and cystic tumor. In this review, Hepatic hemangioma, focal nodular hyperplasia (FNH), Hepatic adenoma, Liver cyst, and Biliary cystadenoma have been summarized. Currently, there is a controversy with the choice of treatment; observation with follow up imaging studies versus resection for incidental hepatic lesions. Surgical indications of benign lesion were symptomatic tumors, tumors having malignant potential. For hepatic hemangioma, due to its benign course, imaging follow-up is not required for typical haemangioma. Surgery is considered when lesions are symptomatic by compression. Surgery is debatable when large hepatic adenoma or lesions with mild symptoms. For a typical FNH lesion, follow-up is not necessary unless there is underlying vascular liver disease. If imaging is atypical, or the patient is symptomatic. Surgery is considered. And asymptomatic adenomas greater than 5 cm is indication for surgery. The management for adenomas is based primarily on imaging criteria, expression of associated immunohistochemical markers and molecular findings. Patients indicated for resection include those with symptomatic tumors or lesions in which malignancy cannot be excluded. The risk of potential complications and the severity of symptoms need to be weighed against surgical risk. The presence of comorbidity, prolonged surgical time and incomplete resections are associated with major morbidity. Recent advanced in minimally invasive surgery including laparoscopic liver resection has become a principle mode of resection for benign hepatic tumors.
Saes Byeol An,Jae Young Choi,Seok Hee Lee,Ying Fang,Jong Hoon Kim,Seung Hee Lee,Shin Sang Woon,Woo Jin Kim,Yeon Ho Je 한국응용곤충학회 2014 한국응용곤충학회 학술대회논문집 Vol.2014 No.04
Rice stripe virus (RSV) is one of the serious plant pathogenic viruses for rice and mediated by small brown planthopper, Laodalphax striatellus. So far, the studies have been mainly focused on the interaction between the host plant and the virus. In this study, for better comprehension of the interactions among Rice stripe virus, rice and small brown planthopper, transcriptomes of the RSV-viruliferous (RVLS) and non-viruliferous L. striatellus (NVLS) were comparatively analysed. For this, non-viruliferous L. striatellus were collected from non-infected rice field and fed RSV-infected rice for 5 days. With the RNAs prepared from the RSV-viruliferous and the non-viruliferous small brown planthoppers, we conducted Illumina RNA sequencing (Hiseq 2000) and then two transcriptome databases were generated from RVLS and NVLS, respectively. The transcriptome of RVLS and NVLS were campared to figure out how the gene expression of the insects affected by Rice Stripe Virus. RSV-dependently regulated genes analysed from this study may have important functions in the transmission and replication of RSV.