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Reliability approximation for a complex system under the stress-strength model
Nayak, Sadananda,Roy, Dilip The Korean Reliability Society 2012 International Journal of Reliability and Applicati Vol.13 No.2
This paper introduces a new approach for evaluating reliability of a complex system in terms of distributional parameters where analytical determination of reliability is intractable. The concept of discrete approximation, reported in the literature so far, fails to meet the latter requirement in terms of distributional parameters. The current work aims at offering a bound based approach where reliability planners not only get a clear idea about the extent of error but also can manipulate in terms of distributional parameters. This reliability approximation has been under taken under the Weibull frame work which is the most widely used model for reliability analysis. Numerical study has been carried out to examine the strength of our proposed reliability approximation via closeness between the two reliability bounds. This approach will be very useful during the early stages of product design as the distributional parameters can be adjusted.
Laparoscopic cholecystectomy for acute cholecystitis: Any time is a good time
Hamza Wani,Sadananda Meher,Uppalapati Srinivasulu,Laxmi Narayanan Mohanty,Madhusudan Modi,Mohammad Ibrarullah 한국간담췌외과학회 2023 Annals of hepato-biliary-pancreatic surgery Vol.27 No.3
Backgrounds/Aims: Laparoscopic cholecystectomy within one week of acute cholecystitis is considered safe and advantageous. Surgery beyond first week is reserved for non-resolving attack or complications. To compare clinical outcomes of patients undergoing laparoscopic cholecystectomy in the first week and between two to six weeks of an attack of acute cholecystitis. Methods: In an analysis of a prospectively maintained database, all patients who underwent laparoscopic cholecystectomy for acute cholecystitis were divided into two groups: group A, operated within one week; and group B, operated between two to six weeks of an attack. Main variables studied were mean operative time, conversion to open cholecystectomy, morbidity profile, and duration of hospital stay. Results: A total of 116 patients (74 in group A and 42 in group B) were included. Mean interval between onset of symptoms & surgery was five days (range, 1-7 days) in group A and 12 days (range, 8-20 days) in group B. Operative time and incidence of subtotal cholecystectomy were higher in group B (statistically not significant). Mean postoperative stay was 2 days in group A and 3 days in group B. Laparoscopy was converted to open cholecystectomy in two patients in each group. There was no incidence of biliary injury. One patient in group B died during the postoperative period due to continued sepsis and multiorgan failure. Conclusions: In tertiary care setting, with adequate surgical expertise, laparoscopic cholecystectomy can be safely performed in patients with acute cholecystitis irrespective of the time of presentation.
Faisal Mousa Alzahrani,Muzaheed,Saeed Sattar Shaikh,,Amer Ibrahim Alomar,,Sadananda Acharya,,Nasreldin Elhadi, 대한진단검사의학회 2019 Annals of Laboratory Medicine Vol.39 No.1
Background: Transfusion-transmissible hepatitis B virus (HBV) infection is a major problem worldwide. Recently, confirmatory nucleic acid tests (NATs) for HBV DNA have been employed in several countries. We assessed the prevalence and yearly trends of HBV infection in blood donors in the Eastern Province of Saudi Arabia, screening for HBV surface antigen (HBsAg), antibody against HBV core antigen (anti-HBc), and HBV DNA. Methods: Between 2011 and 2015, a total of 22,842 donors were screenedfor HBsAg, anti-HBc, and HBV DNA using the HBsAg Qualitative II kit (Abbott, Ireland Diagnostics Division, Sligo, Ireland), ARCHITECT Anti-hepatitis B core antigen antibody (HBc) II Assay kit (Abbott GmbH & Co. KG, Wiesbaden, Germany), and NAT Procleix Ultrio Elite Assay kit (Grifols Diagnostic Solutions Inc., Los Angeles, CA, USA), respectively. Results: A total of 739 (3.24%) donors were HbsAg(+), anti-HBc(+), or HBV DNA(+); 63 (0.28%) were HbsAg(+), anti-HBc(+), and HBV DNA(+). Twelve (0.05%) were anti-HBc(+) and HBV DNA(+) but HBsAg(-); they were considered to have occult infection. Further, 664 (2.91%) were HBsAg(-) but anti-HBc(+), indicating chronic or resolving infection. HBV prevalence increased significantly from 2011 to 2012, increased marginally till 2013, and showed a decreasing trend from 2013 (P>0.05). Conclusions: The five-year prevalence of HBV infection among blood donors in the Eastern Province of Saudi Arabia (3.24%) is lower than that reported for other regions in the country. The occult HBV infection rate of 0.05% emphasizes the importance of NATs in isolating potential infectious blood units.