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      • 대장의 편평샘종과 편평형 조기대장암에서 E-cadherin 및 β-catenin 발현

        진소영,홍사준 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.1

        Backgrounds : Colonic flat adenomas are presented as flat lesion endoscopically and are associated with high incidence of high grade dysplasia and carcinoma even though their small size. Recently reduced membranous expression of cell adhesion complex such as E-cadherin and β-catenin is known to be related to the wide spread and nodal metastasis in human cancers including colon cancers. However, most studies are restricted to the advanced colon cancer and few studies have been done for the colonic adenomas. Object : We tried to evaluate the availability of E-cadherin and β-catenin as the early marker of malignant conversion in flat adenomas of the colon. Materials and Methods : Immunohistochemistry was done using 27 cases of colonic flat adenomas and 7 cases of early colon cancers. Results : The overall reduced membranous expression rate for E-cadherin in colonic flat adenomas and early colon cancer was 44.1%(15/34). Membranous expression was significantly reduced as the degree of dysplasia or carcinoma increase(p<0.05). The overall reduced membranous expression rate for β-catenin was 52.9%(18/34) in colonic flat adenomas and early colon cancers. Non-membranous expression rate for β-catenin (30/34) had a tendency to increase as the degree of dysplasia or carcinoma increase but it was not statistically significant. Non-membranous expression could be seen in the cytoplasm (79.4%) and/or in the nucleus (58.8%). Focal nuclear β-catenin expression was seen in 8 cases and diffuse nuclear expression in 12 cases. Diffuse nuclear β-catenin expression rate was significantly increased as the degree of dysplasia or carcinoma increase(p<0.05). Altered expression of E-cadherin and β-catenin in colonic flat adenomas and early colon cancers was not significantly correlated. Conclusion : Reduced expression of E-cadherin and diffuse nuclear staining of β-catenin can be used as the early marker to predict the malignant conversion in colonic flat adenomas.

      • 자성분말의 초투자율 측정방법과 그 응용

        사공건,전홍배,허 진,김철한 東亞大學校 2001 東亞論叢 Vol.38 No.-

        In this study, a measuring system of the initial permeability of soft-ferrite powder is developed by using a linear variable differential transformer's coil, and investigated about a demagnetizing factor. Magnetic powder is extensively used for a magnetic fluid and microwave absorber's materials etc.. In these applications, it is significantly important for us to measure an initial permeability of magnetic ceramic powder. Unfortunately, there are not any measuring equipment and method directly up to the present.

      • 음성 인식 헬스케어 시스템

        신진우,조우승,조성빈,김재훈,정지은,사예지,백경동,박동규 순천향대학교 부설 산업기술연구소 2021 순천향 산업기술연구소논문집 Vol.27 No.2

        As modern people's interest in health grows, wearable healthcare-related technologies that can collect biometric information and receive health-related services regardless of time and place are developing. This paper proposes the healthcare system based on voice recognition function. Unlike conventional wearable healthcare systems, the proposed system provides real-time telemedicine and diagnosis and the direct connection with doctors is possible through it. And almost all functions of the application in it are operated with voice commands to lower user access barriers. Because it deals with personal information including medical information, encryption algorithms have been applied between all data movements. Finally, the healthcare system proposed in this paper is expected to increase convenience in health care and reduce the medical gap.

      • 면취기 시스템에 있어서 부하의 관성모멘트에 따른 가변 PID 일정 장력제어의 기초연구

        사공건,허 진,전홍배,김철한 東亞大學校 2001 東亞論叢 Vol.38 No.-

        In the winding system, the constant tension control is too important. In this study, we've investigated about a variable PID system as a function of a radius of winding roll. As a result, it was possible to measure a winding roll radius in the real time by making a mathematical model for measuring a winding roll radius. Finally, we've compared PID parameters as a function of winding roll radius after getting PID parameters in terms of the Ziegler & Nichols(ZN) method.

      • 지역사회 체육시설의 현황과 확충 방안 연구

        이사겸,김명진,김창섭,김대진 경희대학교 사회체육연구소 1996 體育科學論叢 Vol.- No.9

        This Study attempted to seek a method for revitalizing the community sports for al related to the sports facilities in order to encourage sports activity according with the regional property. In order to make al well-balanced distribution and untilization of sports for all facilities in Korea a comprehensive evaluation for the demand and trend in the future should be carried out. The expansion of sport facilities for the pubilc, private and one's place of work should be induced and a joint system with sport facilities for schools should be settled. The continuous investment and interacting is more important for the harmonious develolpment in each community than that of unbalanced investment.

      • 후복막강내 발생한 Castleman병 1례

        남성진,이동욱,박찬규,정시욱,김추성,조성래,구본천,양사규,이일웅,박정자 慶北大學校 醫科大學 1997 慶北醫大誌 Vol.38 No.2

        Castleman' s disease is a rare, reactive lymphoid proliferation of unknown cause and pathogenesis. Depending on histololgic findings, it has been divided into two distinct histologic subtypes that include hyaline-vascular type(90%) and plasmacell type(10%). This disease occurs most commonly in mediastinal lymph nodes and cervical lymph nodes, inguinal lymph nodes respectively. But occurs rarely in retroperitoneum. We report a case of hyaline-vascular type asymptomatic Castleman' s disease of the retroperitoneum in a 47-year-old man.

      • 초고집적소자의 층간절연막용 polysilazane계 spin on glass (SOG)에 관한 연구

        나사균,정석철,이재관,김진우,홍정의,이원준 대전산업대학교 반도체기술연구소 2000 半導體技術硏究所報 Vol.2 No.-

        초고집적소자의 층간절연막으로서의 polysilazane계 spin on glass (SOG)의 적용 가능성을 평가하였다. 상용화된 무기 SOG 계열의 polysilazane과 polysilazane에 산화제를 첨가하여 SiO_2로의 변환 능력을 향상시킨 물질을 spin coating하고 curing하여 SOG 막을 제조한 다음, 400℃에서 900℃까지의 온도범위에서 열에 SOG막을 형성하여 gapfill 특성을 비교하였으며, SOG막에 contact hole을 형성한 다음 습식 세정에 대한 저항성을 평가하였다. 산화제를 첨가함으로써 polysilazane polymer 구조에서 SiO_2로의 변환이 더욱 효과적으로 이루어져, 기존 SOG 막에 비해 밀도 및 습식세정 chemical에 대한 저항성이 우수하고거 gapfill 특성은 동등한 수준인 SOG 막을 제조할 수 있었다. 특히, 기존의 SOG 막의 경우 좁은 gap space 내에서 curing이 충분하게 이어나지 않아 습식 세정시 hole profile이 나빠지는 문제를 산화제 첨가를 통해 해결할 수 있었다. We have investigated the feasibility of spin on glass (SOG) film from polysilazane-type resin as a premetal dielectric (PMD) layer of the next-generation ultra-large scale integrated (ULSI) devices. A commercial polysilazane resin and a polysilazane-type resin with oxidzing agent were spin-coated and cured to form SOG films. In order to study the effect of oxidizing agent and annealing, the SOG films were characterized as cured and after annealing at 400℃ to 900℃. The density and the resistance against wet chemical of the SOG films were improved by the addition of oxidizing agent, because oxidizing agent enhanced the conversion from polysilazane polymer to siO_2. The hole profile issue associated with insufficient curing of polysilazane innarrow gaps was alao resolved by oxidizing agent, while the gapfill capability of SOG was not deteriorated by oxidizing agent.

      • (Sr_(1-x)Ca_x)_mTiO_3+yNb_2O_5 세라믹의 주파수 및 온도변화에 따른 유전특성

        김진사,이준웅 광운대학교 신기술연구소 1998 신기술연구소논문집 Vol.27 No.-

        시편은 1350(℃)의 환원분위기에서 소결하여 제작하였으며 소결된 시편의 양면에 금속산화물(CuO)을 도포하여 입계에 침투시켰다. 유전상수는 Ca의 치환량에 따라 15(mol%)까지는 거의 변화가 없었으며 20(mol%)에서는 감소하였고. Nb_20_5의 첨가량이 증가함에 따라서는 증가하였으며 0.8(mol%)이상에서는 감소하였다. 또한 유전손실의 온도특성은 치환 및 첨가량에 관계없이 0.5(%) 이내의 양호한 값을 나타내었다. 사용된 시편은 온도의 함수로서 주파수 증가에 따라 유전완화 현상을 나타내었으며. 완화주파수는 10^6(Hz) 이상이었다 The specimens were fabricated to form semiconducting ceramics by sintering at about 1350(℃) in a reducing atmosphere. After being fired in a reducing atmosphere, metal oxides(CuO) was Painted on the both surface of the specimens to diffuse to the grain boundary. The dielectric constant is not almost variation according to increase the substitutional contents of Ca, but decreased in Ca was exceed (Ca=20(mol%)). It were incrensed with increasing Nb_20_5.but decreased in (Nb_20_5 =0.8(mol%)) was exceed. Also, the temperature characteristics of the dielectric loss factor exhibited a stable value within 0.5(%) then not affectied by substitutional and additive contents. According to increase of the frequency as a functional of temperature, all specimens used in this study showed the dielectric relaxation, and the relaxation frequency was above 10^6(Hz).

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