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The Effect of Sa-am acupuncture on Knee Osteoarthritis
( Moo Hong Min ),( Yeong Gon Choi ),( Yun Ju Kim ),( Hi Joon Park ),( Sam Chool Lee ),( Ho No Joo ),( Seung Moo Han ),( Sa Bi Na Lim ) 대한경락경혈학회 2009 Korean Journal of Acupuncture Vol.26 No.4
Objective: Acupuncture has been widely used throughout the world for the treatment of knee osteoarthritis (knee OA). This study investigated whether acupuncture, particularly Sa-am acupuncture, could be effective in relieving pain and improving the symptoms of knee OA. Method: This study was conducted as a prospective, randomized, controlled, and patient- and investigator- blinded clinical trial. Forty volunteers with knee OA participated in the study. All participants were screened through an inclusion and exclusion criteria. Thirty four participants completed the clinical trial. In total, forty subjects were randomly selected to receive Sa-am acupuncture. Eight sessions of acupuncture were given at the contralateral side of the problematic knee for 4 weeks. Korean translation of Western Ontario and McMaster Universities Osteoarthritis Index (KWOMAC) scores were measured twice: at the beginning and end of the clinical trial period. Both the Patient Global Assessment and physical health scores based on the 36-Item Short-Form Health Survey were also used to measure the results. Results: Compared to the pre-trial scores, the Sa-am acupuncture group (n=34) showed a significant decrease in KWOMAC total scores according to a paired t -test. The Sa-am acupuncture group also showed significant improvement in the Patient Global Assessment when compared to the pre-trial. Conclusions: Sa-am acupuncture for knee OA resulted in an improved KWOMAC total score. This was mostly driven by the function component score that was greatly affected by acupuncture. However, further studies with expanded designs are needed to solidify this finding with scientific rigor.
The Effect of Sa-am acupuncture on Knee Osteoarthritis
Min, Moo-Hong,Choi, Yeong-Gon,Kim, Yun-Ju,Park, Hi-Joon,Lee, Sam-Chool,Joo, Ho-No,Han, Seung-Moo,Lim, Sa-Bi-Na Society for Meridian and Acupoint 2009 Korean Journal of Acupuncture Vol.22 No.1
Objective : Acupuncture has been widely used throughout the world for the treatment of knee osteoarthritis (knee OA). This study investigated whether acupuncture, particularly Sa-am acupuncture, could be effective in relieving pain and improving the symptoms of knee OA. Method : This study was conducted as a prospective, randomized, controlled, and patient- and investigator-blinded clinical trial. Forty volunteers with knee OA participated in the study. All participants were screened through an inclusion and exclusion criteria. Thirty four participants completed the clinical trial. In total, forty subjects were randomly selected to receive Sa-am acupuncture. Eight sessions of acupuncture were given at the contralateral side of the problematic knee for 4 weeks. Korean translation of Western Ontario and McMaster Universities Osteoarthritis Index (KWOMAC) scores were measured twice: at the beginning and end of the clinical trial period. Both the Patient Global Assessment and physical health scores based on the 36-Item Short-Form Health Survey were also used to measure the results. Results : Compared to the pre-trial scores, the Sa-am acupuncture group (n=34) showed a significant decrease in KWOMAC total scores according to a paired t-test. The Sa-am acupuncture group also showed significant improvement in the Patient Global Assessment when compared to the pre-trial. Conclusions : Sa-am acupuncture for knee OA resulted in an improved KWOMAC total score. This was mostly driven by the function component score that was greatly affected by acupuncture. However, further studies with expanded designs are needed to solidify this finding with scientific rigor.
Molecular Cell Biological Study of Ginseng Radix Aqua-acupuncture Solution on Anticancer
Lim,Sa-bi-na,Lee,Hye-jung,Byun,Boo-hyeong INSTITUTE OF ORIENTAL MEDICINE KYUNG-HEE UNIVERSIT 1997 JOURNAL OF ORIENTAL MEDICINE Vol.2 No.1
In order to investigate the anticancer effects of Ginseng Radix aqua-acupuncture solutions. DNA synthesis was measured by the [³H]-thymidine incorporation into NIH3T3 cells. The aqua-acupuncture solutions were made with raw. White and red ginseng by the methods of water-extraction. Water-alcohol and distillation-water-alcohol. The white and red Ginseng Radix aqua-acupuncture solutions by water-alcohol method inhibited DNA synthesis. For the purpose of finding effective concentrations of white and red Ginseng Radix aqua-acupuncture solutions. Cells were treated with various concentrations then examined for their ability to incorporate [³H]-thymidine into the cells. In addition, to identify the active components of Ginseng Radix aqua-acupuncture solution that exert antiproliferative effects. The components were isolated from the Ginseng Radix and its components were evaluated from DNA synthesis. The component of ginsenoside Rh2 appeared to be a stronger inhibitor of cell proliferation compared to Rh 1. This study suggests a potential use of Ginseng Radix aqua-acupuncture solution as an anticancer injection.
임사비나 ( Sa Bi Na Lim ),임형택 ( Hyung Taeck Lim ),박히준 ( Hi Joon Park ),장지련 ( Ji Ryeon Jang ),최일환 ( Il Hwan Choi ),이석찬 ( Seok Chan Lee ),김대수 ( Dae Soo Kim ),신희섭 ( Hee Sup Shin ) 대한경락경혈학회 2004 Korean Journal of Acupuncture Vol.21 No.2
Objective: Acupuncture has been used for treatment of numerous disorders, especially for pain control in Oriental Medicine. However, the mechanism of pain control by acupuncture was not clear until now. This study was performed to prove analgesic mechanism of acupuncture treatment at acupoint ST36 by observing the changes of abdominal pain and c-Fos expression in the thalamus. Methods: Abdominal pain was induced by acetic acid, and the changes of writhing reflex after acupuncture treatment on ST36 and non-acupoints were measured. c-Fos immunohistochemistry was also performed to study the changes of the neuronal activity in the thalamus. Results: The writhing reflex decrease significantly after acupuncturing at ST(36) compared with control group(p<0.05). The changes of the writhing reflex by non-acupoint acupuncture treatment also showed significant decrease compared with control group(p<0.05). c-Fos expression in the thalamus, especially periventricular part was significantly decreased after acupuncturing at ST(36) compared with control groups(p<0.05). Conclusion: This study shows that the acupuncture has the analgesic effect in the abdominal pain induced by acetic acid and the thalamus might be a important area for this mechanism.
Molecular Cell Biological Study of Ginseng Radix Aqua-acupuncture Solution on Anticancer
Lim,Sa-bi-na,Byun,Boo-hyeong,Lee,Hye-jung WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 1997 東西醫學硏究所 論文集 Vol.1997 No.-
In order to investigate the anticancer effects of Ginseng Radix aqua-acupuncture solutions. DNA synthesis was measured by the [³H]-thymidine incorporation into NIH3T3 cells. The aqua-acupuncture solutions were made with raw, white and red ginseng by the methods of water-extraction, water-alcohol and distillation-water-alcohol. The white and red Ginseng Radix aqua-acupuncture solutions by water-alcohol method inhibited DNA synthesis. For the purpose of finding effective concentrations of white and red Ginseng Radix aqua-acupuncture solutions, cells were treated with various concentrations then examined for their ability to incorporate [³H]-thymidine into the cells. In addition. to identify the active components of Ginseng Radix aqua-acupuncture solution that exert antiproliferative effects. the components were isolated from the Ginseng Radix and its components were evaluated from DNA synthesis. The component of ginsenoside Rh2 appeared to be a stronger inhibitor of cell proliferation compared to Rh l. This study suggests a potential use of Ginseng Radix aqua-acupuncture solution as an anticancer injection.
신문혈(神門穴) 침자극(鍼刺戟)이 모성분리(母性分離) 흰쥐의 대뇌(大腦) 변연계(邊緣系)의 c-Fos 발현(發顯)에 미치는 영향(影響)
임사비나 ( Sa Bi Na Lim ),황세희 ( Se Hee Hwang ),류연희 ( Yeun Hee Ryu ),이혜정 ( Hye Jung Lee ),박히준 ( Hi Joon Park ) 대한경락경혈학회 2004 Korean Journal of Acupuncture Vol.21 No.3
Acupuncture has been shown to have therapeutic effects on many mental disorders such as depression, anxiety, and substance abuse in human and animal studies. Maternal separation (MS) is a risk factor in the development of mood-related disorders such as depression. This study investigated the effects of acupuncture during MS by evaluating locomotion as behavioral markers of depression and by observing changes in c-Fos expression in the limbic system (hippocampus, amygdala and cingulate cortex) to elucidate the mechanism of the therapeutic effect. The employed acupoint, Shinmun (HT7), has been clinically used to treat mental disorders. MS for 7 days beginning on postnatal day 14 induced a significant decease in locomotion, while acupuncture treatment at acupoint HT7 resulted in a significant increase in locomotion. c-Fos immunoreactive cells in area dentate gyms (DG) of the hippocampus were increased in the MS group, but significantly decreased in the acupuncture group. These findings suggest that acupuncture has an effect on the depression-like disorder caused by MS, possibly by modulating c-Fos expression in DC of the hippocampus.
하고초약침(夏枯草藥鍼)의 안전성(安全性)에 관(關)한 연구(硏究)
임사비나,Lim Sa-Bi-Na 대한침구의학회 1998 대한침구의학회지 Vol.15 No.2
This experiment was carried out to study on the acute toxicity of Thesium Chinese Turczaninow solution for aqua-acupuncture. Test material was manufactured by 'Water Alcohol method'. Mice and rats were used for this test. According to this experimental results, there were not observed any acute toxicity with Thesium Chinese Turczaninow solution for aqua-acupuncture. So Thesium Chinese Turczaninow solition for aqua-acupuncture is considered a have level of cliniccal safety. It is expected to be clinically helpful, and it is considered that continuous study is necessary.