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Lucian Pîslaru-Dănescu,Elena Chitanu,Lucia-Andreea El-Leathey,Virgil Marinescu,Dorian Marin,Beatrice-Gabriela Sbârcea 대한금속·재료학회 2018 ELECTRONIC MATERIALS LETTERS Vol.14 No.3
The paper proposes a new and complex process for the synthesis of ZnO nanoparticles for antireflective coating correspondingto silicone solar cells applications. The process consists of two major steps: preparation of seed layer and hydrothermalgrowth of ZnO nanoparticles. Due to the fact that the seed layer morphology influences the ZnO nanoparticles proprieties,the process optimization of the seed layer preparation is necessary. Following the hydrothermal growth of the ZnO nanoparticles,antireflective coating of silicone solar cells is achieved. After determining the functional parameters of the solarcells provided either with glass or with ZnO, it is concluded that all the parameters values are superior in the case of solarcells with ZnO antireflection coating and are increasing along with the solar irradiance.
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Unresectable AFP Producing AGC was treated by Neoadj CTx followed by surgery and adj CTx
( Sb Bae ),( Sc Lee ),( Kt Lee ),( Hj Kim ),( Cy Choi ),( Ja Hwang ),( Jh Lee ),( Ms Lee ),( Mw Son ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1
Serum AFP is normally produced in some fetal organs, hepatocytes and HCC. However, AFP levels sometimes are elevated in patients with primary gastric ca. Gastric ca with a high level of AFP is termed AFP producing gastric ca. Prevalence of AFP-producing gastric ca is reported to be 6.2-6.3% in Korea and 15% in the US. Most of cases were a high rate of metastasis to the liver and LNs. We reported a rare case that unresectable AFP producing AGC was treated by neoadj CTx followed by surgery and adj CTx. A 60-years-old man had no history of medication or familiy history. He had nausea, epigastric pain and Physical examination did not show hepatosplenomegaly and epigastric tenderness. GFS revealed BorrmannIII tumor on antral lesser curvature. APCT showed irregular enhancing wall thickening in stomach antrum, lesser curvature, and metastatic LNs around aorta, portal vein, portal, IVC and perigastric area, tumor thrombus in proximal SMV and main portal vein. PET CT showed multiple FDG uptake in perigastric LNs, lt gastric, common hepatic artery and portocaval area. Clinical TNM staging classification according to AJCC was cT4N2/N3M1. GFS bx was adenocaricnoma PD. AFP was elevated at 41,513 ng/mL but, CEA,CA19-9 were normal range. He was performed neoadj CTx by 3cycle DCF [docetaxel 75 mg/m2 D1, cisplatin 75 mg/m2 D1, 5-FU 750 mg/m2 D1-D5] regimen. PET CT was not only markedly decreased wall thickening and FDG uptake but also decreased size and FDG uptake of metastatic perigastric LNs, lt gastric and common hepatic artery area. Patient underwent subtotal gastrectomy with D2 dissection. The resected stomach contained a 3.6 × 2.0 cm BorrmannIII ca. Primary tumor cell invaded subserosa and had a adenocarcinoma MD. Dissected 27 regional LNs were no metastasis. Postop stage was IIA (T3N0M0). Preop AFP was 485 and postop AFP on day 12 and day 24 were 16.88 and 5.41 ng/mL, serial f/u AFP levels were normal until recently. Adj CTx (DCF) was administered on postop day 24, and adverse events of grade 3 of acute kidney injury, febrile neutropenia, nausea and grade 2 of mucositis, vomiting, general weakness had arisen. Patient was treated with 30% dosage reduction and completed with 4 cycle of adj CTx. He had no progression up to now.
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김승보(SB Kim),이재현(JH Lee) 대한산부인과학회 1983 Obstetrics & Gynecology Science Vol.26 No.3
결론 가임기간중 testosterone 활성도의 연령별 추이가 폐경후 활성도를 추구할 목적으로 20대 여성 21예, 40대 여성 42예 및 폐경후 여성 25예를 대상으로 삼아 혈중 testosterone 농도와 TEBG 농도를 측정하고 유리 testosterone분율 및 유리 testosterone 지표를 계산하여 관찰한 결과 다음과 같은 성적을 얻었다. 1. 혈장 TEBG 농도는 월경주기에 따라 아무런 변동도 보이지 않았으나 20대 여성에 비하여 40대여성의 농도는 유의하게 높았고 폐경후에는 다소 감소 경향을 띠우고 있었다. 2. 혈장 testosterone 농도는 연령 진행에 따라 감소 경향을 띠우고 있었으나 개인차가 심하여 유의한 변동을 보이지는 않았다. 3. 월경주기중 혈장 testosterone 농도는 20대 여성 및 40대 여성에서 각각 유의한 변동을 보이지 않았으나 전가임기 여성들을 통합하면 여포기에 비하여 배란전기에 유의한 증가를 보였다. 4. 유리 testosterone 분율은 연령의 증가와 더불어 유의하게 감소하고 있었다. 5. 배란전기의 유리 testosterone 분율은 여포기에 비하여 증가경향을 띠우고 있었으나 유의한 변동은 아니었다. 6. 유리 testorsterone 지표는 개체차가 심하여 연령에 따라 또는 월경주기에 따라 뚜렷한 차이를 보이지는 않았으나 평균치로 보면 연령의 증가와 더불어 상당수준의 감소경향을 띠고 있다. 7. 이상의 성격을 토대로 아래 사항들을 논급 할 수 있다. 가) 가임기간 중에도 연령의 증가와 더불어 testosterone 활성도가 감소하는 바 이는 testosterone 농도의 감소라기 보다는 TEBG 농도가 증가되기 때문이다. 나) 월경주기중 비록 다소간의 testosterone 농도의 변동이 있기는 하나 TEBG 때문에 testosterone 활성도가 변경되지는 않는다. ln order to evaluate the testosterone activities in reproductive women at different ages and postmenopausal women. the plasma testosterone concentration was measured by radioimmunoassay and binding site concentration of TEBG was analyzed by means of ammonium sulphate precipitation method. The percent testosterone free from TEBG was figured out using Rosenthal`s nomogram and free testosterone index was calculated as the product of the total testosterone concentration and the percentage of testosterone free from TEBG. Differences of active testosterone level between young female and aged reproductive women and between reproductives and postmenopausal women were compared. Cyclic pattern of testosterone activity during menstrual cycle was also checked of the women at reproductive age. Followings were the results; 1. There was no significant fluctuation in the binding site concentration of TEBG in peripheral plasma during the menstrual cycle of the normal reproductive women. But the concentration in women varied somewhat according to their ages; the concentration was noted lowest in young reproductive female and it clevated significantly after the age of fourty, followed by a slight decrease after the meno-pause. 2. Only a decreasing trend in total plasma testosterone concentration with progress of age was observed with wide individual variation. 3. The total concentration of plasma testosterone did not shows any change during menstrual cycle for either young female or aged women . Whereas, for whole reproductive women, small but significant elevation of the concentration was observed in the late follicular phase. 4. Percent testosterone free from TEBG were succesively lower in young women. aged reproductive women and postmenopausal women. 5. Percent testosterone free from TEBG remained constant throughout the cycle although the percent showed in the late follicular phase tended to be higher than the early follicular phase. 6. Although there was no definit changes in free testosterone index in accordance with the age or the cycle, the index tended to decrease with progress of age and to decrease with advance of follicle maturation by the mean values being comparable each other. 7. From above results, followings were suggested. A) A decreasing trend in testosterone actiⅵty wlth progress of age, even in reproductive stage, was induced by elevation of the binding site concentration of TEBG rather than decrease of the concentration of total testosterone. B) Cyclic changes of the plasma concentration of total testosterone could not provide any change in testosterone activity during menstrual cycle.
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INDUCED ABORTION IN RURAL KOREA
홍성봉(SB Hong) 대한산부인과학회 1967 Obstetrics & Gynecology Science Vol.10 No.6
PART I INTRODUCTION The majority of countries including Korea prohibit artifficial termination of pregnancy, yet the actual ratio of induced abortions to live births is roughly 1 to 2 in Seoul. Thus, induced abortion affects the birth rate in unban areas of Korea enormousl. (See "Induced Abortion in Seoul, Korea", 1966, by this author) The main reasons for the abortions were found to be family limitation, child spacing and economic difficulty. The author has also pointed out in the preious pubilication that the rising trend in indeuce abortion coincided with the inception of family planning as a fundametal governmental policy. A new value orientation and the family planning campaign have been propagated in the country on a wide scale. The proportion of contraceptive users in rural areas at present is comparable to that in Seoul in Spring 1964. As the proportion of practitioners in rural areas increases gradully, it is anticipated that incidence of induced abortion will follow a similar trend. The population of rural areas in Korea constitutes 70 per cent of the total. Thus, fact finding about induced abortion in rural areas is essential in order to complete the picture of induced abortion in the whole of Korea. This will complement the subject together with the data collected from Seoul in 1964. Moreover, an agricultural population maintains, in general, homegeneity of social background and rather lower economic standards, which will affect the patterns of induced abortion in comparison with that of urban areas. These are the reasons for undertaking a field study in a rural area. It is said that where the legal supervision of induced abortion is strict, exploration of factual data is difficult to undertake as has been experienced in the United States. How- ever, in Korea the proportion of women who feel guilty about resorting to induced abortion is relatively small. Furthermore, actual prosecution against criminal abortion is rarely reported unless the maternal damage subsequent to the abortion is unbearable. Wives, therefore, discuss the subject without hesitation or reticence. These provide favorable conditions for the elucidation of facts about induced abortion in Korea. DEMOGRAPHIC BACKGROUND AND SAMPLES For this study, Yongi-Gun, Chungchong-namdo, was chosen as the study area and eligibility was defind as wives aged 20 to 44 years who were living with their husbands at the time of interview. Yongi-Gun, the study area, one of counties in Chungchong-namdo Province, is located approximately in the center of South Korea, and is considered to represent one of the typical rural areas of Korea in terms of cultural, social and ecoomic conditions. This judgment is based on statistical data relative to Yongi-Gun which shows similarity in comparison with data of other counties. (The Statistical Yearbook, 1965, by the Provincial Government). Yongi-Gun, Located 75 miles away from the capital city, Seoul, had a population of 108,330 as of December 1, 1964, and comprised six Myuns or 189 Ris. Its county govern- ment is located at Chochiwon-Eup. Since the study is concerned with a typical rural area, Chochiwon-Eup and Bongam-Ri were excluded from the universe. The former is a medium- sized town where the county office is located and is more or less urban oriented. A railway station called "Chochiwon" is located here. Bongam-Ri contains military bases with a demographically aberrant population. Both were omitted from the universe because of their incompatibility with the typical rural pattern.
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Cho, SB,Zheng, Z,Cho, S,Ahn, KJ,Choi, MJ,Kim, D-Y,Lee, KH,Bang, D Informa Healthcare 2013 Scandinavian journal of rheumatology Vol.42 No.3
<P><B>Objectives:</B> Heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 has been identified as a target antigen of anti-endothelial cell immunglobulin (Ig)A antibodies in patients with Behçet’s disease (BD). The aim was to investigate the effects of the sera from BD patients and <I>Streptococcus sanguis</I> on the subcellular expression of hnRNP A2/B1 in human dermal microvascular endothelial cells (HDMECs).</P><P><B>Method:</B> The sera of BD patients and healthy controls (HC) as well as cultured <I>S. sanguis</I> were used to stimulate HDMECs. Subcellular fractions were obtained from stimulated HDMECs and were subjected to immunoblot analyses. The distribution of hnRNP A2/B1 was investigated by immunocytochemistry and direct immunofluorescence study was performed in biopsy specimens of mucosal ulcers from BD patients.</P><P><B>Results:</B> BD patients’ sera increased the membrane expression of hnRNP A2/B1 in HDMECs after 12 and 24 h of incubation compared with HDMECs incubated with endothelial cell culture media and HC sera. <I>S. sanguis</I> also increased hnRNP A2/B1 in the cellular membrane. hnRNP A2/B1 mRNA level was also significantly upregulated in HDMECs incubated with BD patients’ sera and <I>S. sanguis</I>. Immunocytochemistry demonstrated marked expression of hnRNP A2/B1 in the cytoplasm and cellular membrane of HDMECs incubated with BD patients’ sera or <I>S. sanguis</I>. In addition, direct immunofluorescence experiments revealed the co-localization of serum IgA antibodies and monoclonal antibodies (mAbs) against hnRNP A2/B1 in tissue sections from ulcers of BD patients.</P><P><B>Conclusions:</B> Our data indicate that both the sera of BD patients with active disease and <I>S. sanguis</I> infection are inflammatory stimuli that can induce membranous hnRNP A2/B1 expression in HDMECs.</P>
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