Preparation, Characterization and Properties of High-salt-tolerance Sodium Alginate/Krill Protein Composite Fibers

Rui Zhang,Jing Guo,Jing Wu,Miao Zhao,Yuanfa Liu,Yue Yu 한국섬유공학회 2018 Fibers and polymers Vol.19 No.5

Sodium alginate (SA) and krill protein (AKP) were blended to obtain composite solution, and functional SA/AKP composite fibers were prepared via wet spinning. To further improve the salt tolerance, SA/AKP composite fibers were modified with copper sulfate aqueous solution as secondary coagulation bath because of the strong adsorption to copper ions. The CSA/AKP composite fibers with high salt tolerance have been successfully prepared. The intermolecular interaction of SA/AKP composite system and the two-order structure of protein in the composite system were characterized by Fourier transform infrared spectroscopy (FT-IR). Besides, the crystallinity, morphology, mechanical properties, salt tolerance and water resistance and thermal stability of SA/AKP composites were investigated respectively. The results showed that the adsorption rate and the adsorption capacity of the composite solution to copper ion were significantly higher than those to calcium ion. Under the effect of secondary solidification by copper sulfate, the β-sheet chain of the composite fibers increased from 41.48 % to 49.21 %, the intramolecular hydrogen bond increased from 38.18 % to 44.26 %, the intermolecular hydrogen bond decreased from 59.84 % to 54.70 % and free hydroxyl slightly decreased. The water resistance of the modified composite fibers was improved by about 22 %; when the swelling time was 25 min, the salt resistance increased by about 150 %; the number of grooves on the surface of the composite fibers obviously increased, and the grooves on the surface of CSA/AKP composite fibers and the fiber section structure were much denser; Meanwhile, copper sulfate had some influence on the crystallization, thermal stability and mechanical properties of the composite fibers.

Endothelial Progenitor Cells’ Classification and Application in Neurological Diseases

Jing-jing Yuan,Jing Yang,Shi-lei Sun,Rui Zhang,Yu-ming Xu 한국조직공학과 재생의학회 2017 조직공학과 재생의학 Vol.14 No.4

The therapeutic effects of endothelial progenitor cells (EPCs) on ischemic stroke have been extensively studied in recent years. However, the differences in early EPCs and endothelial outgrowth cells (EOCs) are still unclear. Clarifications of their respective properties and specific functioning characteristics contribute to better applications of EPCs in ischemic diseases. In this review, we discuss cellular origin, isolation, culture, surface markers of early EPCs and EOCs and relevant applications in neurological diseases. We conclude that EOCs possess all characteristics of true endothelial progenitors and have potent advantages in EPC-based therapies for ischemic diseases. A number of preclinical and clinical applications of EPCs in neurological diseases are under study. More studies are needed to determine the specific characteristics of EPCs and the relevant mechanisms of EPCs for neurological diseases.

RUNES II : A Distributed Rule Engine Based on Rete Network in Cloud Computing

Rui Zhou,Guowei Wang,Jinghan Wang,Jing Li 보안공학연구지원센터 2014 International Journal of Grid and Distributed Comp Vol.7 No.6

In recent years, cloud computing has drawn more and more attention. Increasingly amount of systems and applications have been constructed in cloud environments, yet few researches of rule engine has been done. Rule engine technologies have been widely used in the development of enterprise information systems. These rule-based systems may encounter the problem of low performance, when a large amount of fact data are matched with these rules. Deploying rule engines in cloud environments can increase the capability and efficiency of these systems. In this paper, we propose an approach to implement rule engine based on a message-passing concurrency model in cloud computing. The approach can be extended conveniently and it can deal with extensive rules and facts efficiently. To improve the performance of the rule engine, an algorithm of allocation is proposed. A resource cost model is explored to make high efficient use of resources in cloud. In addition, we implement the rule engine system RUNES II in cloud platform and conduct experiments to show its performance.

Isolation of Eight DM domains of Dmrt genes in Rana Livida (Amphibia: Anura)

Rui Jia,Liu Wang Nie,Jing Jing Wang,Ning Wang 한국유전학회 2008 Genes & Genomics Vol.30 No.6

The Dmrt gene family encodes putative transcription factors, sharing a highly conserved DNA-binding domain-the DM domain, related to the sexual regulators Doublesex from Drosophila melanogaster and MAB-3 from Caenorhabditis elegans. Besides sex determination or differentiation, this gene family has evolved to adopt functions in other developmental pathways. In this paper, eight distinct DM related transcription factor (Dmrt) genes from both male and female and detected using PCR and the SSCP technique. No sexual differences were observed. These fragments (named RlDmrt1a, RlDmrt1b, RlDmrt2a, RlDmrt2b, RlDmrt2c, RlDmrt3, RlDmrt4, RlDmrt5) exhibited 98%, 98%, 95%, 95%, 95%, 99%, 92% and 83% similarity respectively to the corresponding homologous human Dmrt genes. Phylogenetic analysis based on DM domain amino acid sequence similarities suggested that vertebrate and invertebrate Dmrt genes can be grouped into seven distinct subfamilies. Interestingly, sequence analysis further illustrates that the gene Dmrt1 and 2 found in R. livida are duplicated. The DM domains of R. livida genes contained two conserved zinc-chelating sites (CCHC and HCCC). Identification of these genes is a potential step in understanding development regulations including sex determination in green cascade frog.

hARIP2 is a Putative Growth-promoting Factor Involved in Human Colon Tumorigenesis

Gao, Rui-Feng,Li, Zhan-Dong,Jiang, Jing,Yang, Li-Hua,Zhu, Ke-Tong,Lin, Rui-Xin,Li, Hao,Zhao, Quan,Zhang, Nai-Sheng Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20

Activin is a multifunctional growth and differentiation factor of the growth factor-beta (TGF-${\beta}$) superfamily, which inhibits the proliferation of colon cancer cells. It induces phosphorylation of intracellular signaling molecules (Smads) by interacting with its type I and type II receptors. Previous studies showed that human activin receptor-interacting protein 2 (hARIP2) can reduce activin signaling by interacting with activin type II receptors; however, the activity of hARIP2 in colon cancer has yet to be detailed. In vitro, overexpression of hARIP2 reduced activin-induced transcriptional activity and enhanced cell proliferation and colony formation in human colon cancer HCT8 cells and SW620 cells. Also, hARIP2 promoted colon cancer cell apoptosis, suggesting that a vital role in the initial stage of colon carcinogenesis. In vivo, immunohistochemistry revealed that hARIP2 was expressed more frequently and much more intensely in malignant colon tissues than in controls. These results indicate that hARIP2 is involved in human colon tumorigenesis and could be a predictive maker for colon carcinoma aggressiveness.

해외직접구매 온라인 쇼핑몰의 특성, 지각된 유용성, 재이용의도의 관계에 관한 연구

팽정예(Jing Rui Peng),최동오(Dong Oh Choi),유천(Cheon Yu) 국제e-비즈니스학회 2022 e-비즈니스 연구 Vol.23 No.3

Naturally Occurring Lactic Acid Bacteria Isolated from Tomato Pomace Silage

Wu, Jing-Jing,Du, Rui-Ping,Gao, Min,Sui, Yao-Qiang,Xiu, Lei,Wang, Xiao Asian Australasian Association of Animal Productio 2014 Animal Bioscience Vol.27 No.5

Silage making has become a significant method of forage conservation worldwide. To determine how tomato pomace (TP) may be used effectively as animal feed, it was ensilaged for 90 days and microbiology counts, fermentation characteristics and chemical composition of tomato pomace silage (TPS) were evaluated at the 30th, 60th, and 90th days, respectively. In addition, 103 lactic acid bacteria were isolated from TPS. Based on the phenotypic and chemotaxonomic characteristics, 16S rDNA sequence and carbohydrate fermentation tests, the isolates were identified as 17 species namely: Lactobacillus coryniformis subsp. torquens (0.97%), Lactobacillus pontis (0.97%), Lactobacillus hilgardii (0.97%), Lactobacillus pantheris (0.97%), Lactobacillus amylovorus (1.9%), Lactobacillus panis (1.9%), Lactobacillus vaginalis (1.9%), Lactobacillus rapi (1.9%), Lactobacillus buchneri (2.9%), Lactobacillus parafarraginis (2.9%), Lactobacillus helveticus (3.9%), Lactobacillus camelliae (3.9%), Lactobacillus fermentum (5.8%), Lactobacillus manihotivorans (6.8%), Lactobacillus plantarum (10.7%), Lactobacillus harbinensis (16.5%) and Lactobacillus paracasei subsp. paracasei (35.0%). This study has shown that TP can be well preserved for 90 days by ensilaging and that TPS is not only rich in essential nutrients, but that physiological and biochemical properties of the isolates could provide a platform for future design of lactic acid bacteria (LAB) inoculants aimed at improving the fermentation quality of silage.

Fotemustine, Teniposide and Dexamethasone in Treating Patients with CNS Lymphoma

Wu, Jing-Jing,Wang, Xin-Hua,Li, Ling,Li, Xin,Zhang, Lei,Sun, Zhen-Chang,Fu, Xiao-Rui,Ma, Wang,Chang, Yu,Zhang, Xu-Dong,Han, Li-Juan,Zhang, Ming-Zhi Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.11

Purpose: We developed and evaluated a regimen including fotemustine, teniposide and dexamethasone (FTD) for treating patients with central nervous system (CNS) lymphoma based on pharmacokinetic properties of individual agents and in combination. Patients and Methods: In a comparison study, 8 patients with primary CNS lymphoma (PCNSL) and 8 with secondary CNS lymphoma (SCNSL) were treated with FTD (comprising fotemustine 100 mg/m2, 1h infusion, day 1; teniposide 60 mg/m2, >0.5 h infusion, on day 2, 3, 4; dexamethasone 40 mg, 1h infusion, on day 1, 2, 3, 4 and 5; and methotrexate 12 mg, cytosine arabinoside 50 mg plus dexamethasone 5 mg intrathecally, on day 2 and 7). Cycles were repeated every 3 weeks. After response assessment, patients received whole brain radiotherapy. Results: Of the 8 PCNSL patients, 4 (50%) achieved CR and 3 (38%) PR, an overall response rate of 88%. Four patients (50%) were in continuing remission at the end of this study after a median follow-up of 30 months (range 10 to 56 months). Of the 8 SCNSL patients the overall response rate was 63% (CR+PR: 38%+25%). All responses were achievable with predictable toxicity mainly reflecting reversible myelosuppression. Conclusion: This study suggests that FTD could be an effective treatment for CNS lymphoma, and is worthy of further evaluation.

Total Delay for Treatment among Cancer Patients: a Theory-guided Survey in China

Feng, Rui,Wang, De-Bin,Chai, Jing,Cheng, Jing,Li, Hui-Ping Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.10

Purpose: This study aimed at exploring treatment delay (TD) among cancer patients in China with an attempt to develop a practical methodology facilitating frontline Chinese clinicians in promoting earlier cancer diagnosis and treatment. Materials and Methods: The study comprised framework development, qualitative interviews and paired factor rating. Framework development utilized systematic literature review, soft systems thinking and consensus groups. Qualitative interviews employed a checklist of open questions soliciting information about all the domains included the framework from cancer patients drawn via stratified randomized sampling of inpatients at 10 hospitals in Hefei, China. Paired factor rating used a self-developed computer aid and the interviewed patients as referring cases to weigh the relative importance of the factors listed in the framework in terms of their contributions to specific components of total delay (TD). Results: a) A conceptual framework was proposed consisting of a 6-step path to TD and 36 category determinants. b) A total of 227 patients were interviewed; their TD was 267.3 mean or 108 median days ranging from 0 to 2475 days; average appraisal, illness, behavioral, preparation and treatment delay accounted for 52.1%, 9.4%, 0.30%, 8.8% and 29.4% of the TD respectively. Individual side factors were rated substantially more important than environmental side factors (60% vs. 40%); most influential TD factors included cancer symptoms, overall health, family relations and knowledge about cancer and health. Conclusions: The framework proposed together with the interviewing and rating approaches used provide a potential new methodology for understanding cancer patients' TD and promoting earlier cancer treatment.

영화 속에 나타난 중국적 요소의 반영

류징루이(Liu Jing Rui),최원호(Won-Ho Choi) 한국콘텐츠학회 2019 한국콘텐츠학회 종합학술대회 논문집 Vol.2019 No.5