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Ri Hua Jin,Young Lee 한국아동학회 2014 Child studies in Asia-Pacific context Vol.4 No.2
The purpose of this study was to investigate Chinese parents`` reaction to their children``s negative emotions and how these reactions relate to their children``s understanding of emotions. Forty two Chinese children (aged 4) and their parents participated in this study. Coping with Children``s Negative Emotion Scale was given to parents to assess their reaction to their children``s negative emotions. Children``s emotional understanding was assessed using the modified emotional false-belief task and mixed emotion task. The results showed that Chinese parents gave supportive reactions more than non-supportive reactions to their children, and no difference in sex was found. The percentages of correct answers to false-belief task and mixed emotion task were low with no gender difference in both tasks. When age and sex of children were controlled, only fathers`` supportive reactions to children``s negative emotions significantly explained the variances in the level of children``s understanding of emotions in both tasks. That is, children whose fathers showed greater supportive reactions to their negative emotions performed better at both tasks. It was concluded that fathers`` supportive reactions to their children``s negative emotions are very influential for emotional understanding among 4-year-old children in China.
Preparation and Evaluation of Freeze-dried Solid Lipid Nanoparticles with Various Cryoprotectants
Li, Ri Hua,Seo, Seung-Yong,Eun, Jae-Soon,Lee, Mi-Kyung The Korean Society of Pharmaceutical Sciences and 2010 Journal of Pharmaceutical Investigation Vol.40 No.1
Solid lipid nanoparticles (SLNs) were freeze-dried to obtain a stable solid dosage form with the aid of various cryoprotectants such as trehalose, sucrose, glucose, fructose, and glycerol. Tricaprin(TC) and trilaurin(TL) were used as lipid matrices for SLNs and stabilizers were egg phosphatidylcholine and pegylated phospholipid. All cryoprotectants tested did not cause changes in mean particle size of SLNs when mixed with SLNs before freeze-drying. However, the mean particle sizes of reconstituted SLNs after freeze-drying were significantly different from those of the un-lyophilized original SLN dispersions depending on the types and concentration of cryoprotectants. Although the freeze-dried SLNs without any cryoprotectants were easily reconstituted by hand-shaking, the mean particle size drastically increased (> $8\;{\mu}m$ for TC SLNs and around $1\;{\mu}m$ for TL SLNs) compared to that of un-lyophilized original dispersion (97 nm for TC SLNs and 164 nm for TL SLNs). Trehalose and sucrose were the most effective additives to protect the SLNs during lyophilization. The reconstituted SLNs were physically stable for 24 hours when lyophilized with 12.5% trehalose, sucrose, glucose, fructose or glycerol.
Zhen-Hua Chen,Liang-Peng Sun,Wei Zhang,Qiang Shen,Li-Xin Gao,Jia Li,Hu-Ri Piao 대한화학회 2012 Bulletin of the Korean Chemical Society Vol.33 No.5
Protein tyrosine phosphatase 1B (PTP1B) is a key factor in negative regulation of the insulin pathway, and is a promising target for the treatment of type-II diabetes, obesity and cancer. Herein, compound (4) was first observed to have moderate inhibitory activity against PTP1B with an IC50 value of 13.72 ± 1.53 μM. To obtain more potent PTP1B inhibitors, we synthesized a series of chalcone derivatives using compound (4) as the lead compound. Compound 4l (IC50 = 3.12 ± 0.18 μM) was 4.4-fold more potent than the lead compound 4 (IC50 = 13.72 ± 1.53 μM), and more potent than the positive control, ursolic acid (IC50 = 3.40 ± 0.21 μM). These results may help to provide suitable drug-like lead compounds for the design of inhibitors of PTP1B as well as other PTPs.
김일 ( Ri Jin ),최화 ( Hua Cui ),어금항 ( Jin Hang Yu ),구희영 ( Hee Yeong Ku ),정해연 ( Hai Yan Zheng ),김문성 ( Wen Cheng Jin ),이규석 ( Kyoo Seock Lee ) 한국환경복원기술학회(구 한국환경복원녹화기술학회) 2012 한국환경복원기술학회지 Vol.15 No.1
To investigate the air temperature difference between windward and leeward side at high-rise building area, the air temperature and relative humidity data were observed for 10 minute interval from July 9, 2011 to November 30, 2011. The observed data were compared, analyzed and examined to illustrate air temperature between windward side (H Apartment) and Leeward side (W Apartment). The diurnal and seasonal variation of air temperature difference between windward and leeward site were also investigated. After the analysis, the overheat of windward side by 0.4℃ irrespective short distance of two observation positions. It was also lower than those of surrounding air temperature observing stations. It is mainly due to the air temperature decreasing effects of leeward side of high rise buildings.
CT Findings of an Ectopic Pancreas in the Anterior Mediastinum
Zu-Hua Chen,Ri-Sheng Yu,Fei Dong,Xiu-Juan Wang 대한영상의학회 2009 Korean Journal of Radiology Vol.10 No.5
We report here on a rare case of an ectopic pancreatic tissue in the anterior mediastinum. A 32-year-old woman without any symptoms was transferred to our hospital because of an abnormal large mediastinal shadow on her chest radiograph during a checkup. The computed tomography (CT) scan revealed a giant cystic-solid mass that measured 16 × 13 × 8 cm and it was located in the center of the anterior mediastinum and it symmetrically grew to two sides. On enhanced CT scans, the solid component of the mass showed marked enhancement. We performed total surgical resection of the mass and complete pancreatic tissues were verified on the pathological examination.