The effects of antibiotics on the reproductive physiology targeting ovaries in the Asian tiger mosquito, Aedes albopictus

Ha Young‐Ran,Jeong Se‐Jin,Jang Chang‐Won,Chang Kyu‐Sik,Kim Hyun‐Woo,Cho Shin‐Hyoung,Lee Hee‐Il 한국곤충학회 2021 Entomological Research Vol.51 No.2

Mosquitoes have adapted to various environmental conditions. Symbionts with mosquitoes impact this adaptation in different environments. In the field, mosquitoes could get exposed to antibiotics during their developmental period, which could reduce or eliminate their symbiotic microbes. However, the side effects of the antibiotics on the ovary and reproductive physiology of the Asian tiger mosquito, Aedes albopictus remains unknown. In this study, we investigated the effects of tetracycline and combinations of rifampicin and tetracycline at environmentally acceptable levels on the reproductive physiology of ovaries in Ae. albopictus. Rifampicin and tetracycline in combination reduced the hatching rate and fertility of Ae. albopictus compared to the untreated control group. These antibiotics induced histopathological damage and reactive oxygen species production in the ovaries. The combination of antibiotics decreased the expression of surface protein of Wolbachia (WSP) in Ae. albopictus. Additionally, the expression of Toll like receptor 2 (TLR2) and Myd88 were triggered by the combinations. The findings demonstrate the detrimental effects of antibiotics, particularly combinations of rifampicin and tetracycline, on the reproductive capacity of Ae. albopictus females.

신라검무 및 동일강도의 트레드밀 운동시 심박수, RPE 및 혈중 젖산농도 변화의 비교

오향란,안나영,김기진 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

This study was performed the comparison of physiological function between a sword dance and treadmill running, For the positive factors of sword dance through physical activity and music component on the psycho-hysiological change. Subjects were consisted of 20-aged 16 female sword dancer of 2 groups, as skillful dancer group(n=B) and novice group(n=B), The results were as follow: In graded maximal testing, VO₂max, anaerobic threshold, and recovery capacity after maximal exercise in skillful group showed a higher than novice group. Change of heart rate during a sword dancing is almost similar level to optimal intensity in aerobic exercise program, so sword dance could be suggested an effective exercise program Physiological stimulus to cardiopulmonary function is different response as the different career of sword dance, because novice group showed a significant(p<.05) higher heart rate in sword dance than treadmill running. Blood lactate concentration showed a similar response between sword dancing and treadmill running in both 2 groups. Novice group showed a higher RPE in sword dancing than treadmill running, but skillful group showed a lower RPE in sword dancing than treadmill running. These results mean that the acquainted level of sword dance affected to the psychological response during sword dancing In these result, hypothesis of the similar blood lactate change between sword dancing and treadmill running could be accepted, but RPE is different response as the different career of sword dance.

Effect of TiO2@Carbon Nanotubes and Praseodymium on the Microhardness and Corrosion Properties of AZ91 Alloy

Qianwen Ran,Hong Yan,Jiajia He,Ning Li,Yushun Lei 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.8

Effect of 1 wt% TiO2@carbon nanotubes (TiO2@CNTs) and 1 wt% praseodymium (Pr) on the microhardness and corrosionproperties of AZ91 magnesium alloy were discussed. The microhardness test, electrochemistry test that AZ91 magnesiumalloy with 1 wt% TiO2@CNTs and 1 wt% Pr addition exhibits excellent microhardness (111 HV), low corrosion currentdensity (0.165 mA·cm−2), and low polarization resistance (537.15 Ω·cm2) compared with AZ91 magnesium alloy (89 HV,0.184 mA·cm−2, 261.06 Ω·cm2). After 1 wt% TiO2@CNTs and 1 wt% Pr added to AZ91, the average crystallite size wasreduced and microhardness was increased. Additionally, the Al11Pr3phase formed by the combination of Pr and Al transformedthe morphology of β-Mg17Al12 phase into weeny particles and decreased the volume fraction of β-Mg17Al12 phase. The reduction and refinement of cathode phase (β-Mg17Al12 phase) weakened the micro-galvanic corrosion and sloweddown the corrosion rate.

Protective Effect of Curcumin and Aqueous Extract of Onchengyeum on CCl_(4)-induced Hepatotoxicity

Seung, Keum Ran,Jung, Ki Hwa 덕성여자대학교 대학원 2005 덕성여자대학교 대학원 논문집 Vol.7 No.-

An aqueous extract of oriental herbal composition named Onchengyeum and curcumin, an antioxidant isolated from turmeric (Curcuma longa Linné) reduced hepatotoxicity induced by carbon tetrachloride (CCl_(4)). Improved liver function was observed by measuring the activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), blood urea nitrogen (BUN), creatinine (CRE), total cholesterol (TCHO), triglyceride (TG), low density lipoprotein cholesterol (LDL-CHO), high density lipoprotein cholesterol (HDL-CHO), total protein (TP), albumin (ALB) and total bilirubin (BIL) in serum. Hepatic parameters monitored were levels of cholesterol (CHO), triglyceride (TG), malondialdehyde (MDA) and content of cytochrome P450 (CYP), level of glutathione (GSH), activities of NADPH-CYP reductase, superoxide dismutase (SOD), catalase (CAT), glutathione S-transferase (GST), glutathione reductase (GR), glutathione peroxidase (GPx). The histopathological examination showed that the treatment of Onchengyeum and curcumin relieved the ballooning degeneration of hepatocytes which had been generated by CCl_(4). The results suggested that hepatoprotective effects of Onchengyeum and curcumin possibly are due to their promising antioxidative activity.

Determination of Acyl-lysophosphatidic Acid in Plasma by Tandem Mass Spectrometry

Yoon, Hye-Ran 덕성여자대학교 약학연구소 2005 藥學論文誌 Vol.16 No.1

Analysis of acyl lysophosphatidic acids(LPAs) has clinical importance as a potential biomarker for ovarian and other gynecological cancers or obesity in the aspect of prevention. Here we report simple sample preparation and analytical method developed with high sensitivity and specificity for the early detection of gynecological cancers to improve the overall outcome of this disease. We established a novel quantification method of acyl-LPAs in plasma by electrospray negative ionization tandem mass spectrometry (MS-MS) using multiple reaction monitoring mode without conventional TLC step. Protein-bound lipids, acyl-LPAs in plasma were extracted with methanol : chloroform (2:1) containing LPA C14:0 as internal standard under acidic condition. Following back extraction with chloroform and water, centrifuged lower phase was evaporated and reconstituted in methanol and then analyzed. Using ESI-MS-MS with negative ionization MRM mode, all the species of LPAs were completely separated from plasma matrix without severe interferences. For MRM mode, Q1 ions selected were m/z 409, 433, 435, 437 and 457 which corresponds to molecular mass [M-H]- of C16:0, C18:2, C18:1, C18:0 and C20:3 LPA, respectively. Q2 ions selected for MRM was m/z 79, phosphoryl product. Using MS/MS with MRM mode, all the species of LPAa were completely separated from plasma matrix without severe interferences. This method allowed simultaneous detection and quantification of different species of LPAs in a plasma over a linear dynamic range of 0.01 - 25 (mol/L. The method detection limit was 0.3 pmol/ml with correlation coefficient of 0.9983 in most LPAs analyzed. When applied to the plasmas with normal and gynecological cancer patient, this new method differentiated two different groups by way of total LPA level.

巴金의 《추운 밤》의 현실주의 연구

朴蘭英 中國語文硏究會 1992 中國語文論叢 Vol.5 No.-

巴金小说中的韩国人形象研究——以《火》为中心

박난영 水原大學校 2014 論文集 Vol.28 No.-

This thesis examines Bajin's understanding of Koreans through observing Korean figures in <The Story of Hair> and 《Fires》. Firstly, because the basis for the two pieces was You Ja-myung, an pro-independece anarchist in China, his life will be explored in advance. After Korea became separated, studies on the independence movement of nationalistic or communistic perspective was active while research on anarchists were rare. Shedding new light upon his activity may fill up the vacancy created meanwhile. Secondly, borderless friendship between Korean and Chinese anarchists who stand up against oppressors hindering construction of a free, equal society during the Sino-Japanese War will be appraised. It may allow us to have a closer look at the original form of a cosmopolitan we now aspire. As observed in <The Story of Hair> and 《Fires》, Bajin understands Korean's circumstances mainly through interacting with Korean anarchists and builds friendships transcending nationality. In the end, the perspective toward viewing human and the world and acting accordingly is a matter of importance in value judgment not only in the past history but also in current cases.

1920년대 巴金 아나키즘 연구

박난영 중국어문연구회 2000 中國語文論叢 Vol.19 No.-

本論文是以1920年代巴金的無政府主義爲硏究對象, 把1920年代以他的人生歷程, 劃分爲成都市期, 上海·南京時期以及法國時期, 來探討巴金無政府主義思想. 在成都時期, 巴金從新文化運動潮流中接受無政府主義而希望卽刻實現萬人享樂的新社會. 他參加 '均社'以後, 自稱爲無政府主義者, 不但批判以政府·法律·資本家委象徵的現存社會制度, 而且更要建立以自由和平等爲基礎的無政府共産主義社會. 在上海·南京時期, 他以飜譯無政府主義的理論著作以及編寫革命傳記, 種介紹無政府主義的一般宣傳, 深入地探討無政府主義的根底和原理, 他主張在自由聯合的基礎上, 以互助的形式來創造全人類所需要的麵包, '麵包'與 '自由'的綜合表現就是克魯泡特金的理想的無政府共産主義社會, 這也就是巴金的理想. 在法國時期, 他爲了營球意大利無政府主義自薩珂和凡宰特運動, 而接觸世界著名的無政府主義者. 他藉着出版<平等>, 不但把世界無政府主義運動的動向介紹到中國, 而且探討在中國如何進行無政府主義運動. 在這種活動的根底上, 具有超越民族主義的限制而追求無政府主義的世界性和普遍性. 巴金把無政府主義一直作爲自己的信仰, 一般來說, 大家都認爲無政府主義是不可能現實的一個夢想. 但是改變現實的實踐運動, 不是由特定的理念所獨占而 完成的. 無政府主義主張由互相扶助的共同體來代替資本主義的競爭體制, 由自由主義的自治社會來代替權威的階級獨裁, 由小規模聯合社會來代替强權的國家體制. 這樣, 無政府主義才是二十一世紀時代的一個座標.

當歸四逆湯이 Endotoxin으로 誘發된 白鼠의 血栓症에 미치는 影響

崔蘭淑,金塋均 동의대학교 한의학연구소 1998 동의한의연구 Vol.2 No.-

The experiment reached these conclusions in consequence of measurement of effect of Dangguisayouktang on the intravascular coagulation induced by Endotoxin in Rats 1. Leukocyte increased in number significantly on the sample's seacond day in comparison with the control group. 2. Hematocrit increased in rate significantly oil the sample's first and third day in comparison with the control group. 3. Hemoglobin increased in quantity significantly on sample's third day in comparison with the control group. 4. MCV had not any significant change in comparison with the control group. 5. Platelet decreased in number significantly on the sample's second day in comparison with the control group. 6. Prothrombin time decreased significantly on the sample's first day in comparison with the control group. 7. FDP concentration increased on the sample's second day in comparison with the control group.

균형직교 중심합성계획법

정란숙,김기호 중앙대학교 통계연구소 1998 統計論文集 Vol.- No.5

중심합성계획은 반응표면방법론에서 일반적으로 사용하는 반응표면계획법이다. 이때 중심합성계획이 같은 블록크기와 직교블록을 만족하도록 적절한 축점의 값 α을 찾아준다. 본 연구에서는 실험의 편리함과 분석의 효율성을 고려하여 이러한 균형직교 중심합성계획법을 연구하였다.