중국 “신창타이” 시대의 재정지출이 취업에 미치는 영향

심권평 ( Shen Quan-ping ),김종섭 ( Kim Jong-sup ) 국제지역학회 2017 국제지역학회 춘계학술대회 Vol.2017 No.-

2007년 이후 중국경제는 고속성장에서 중·고속성장으로 변화되면서 “신창타이”시대에 진입함과 더불어 경제·사회적으로 큰 변화를 나타내고 있으며 새로운 패러다임하에 취업문제가 큰 관심을 받게 되었다. 따라서 국가경제의 발전과 조절에서 중요한 역할을 하고 있는 재정지출이 취업에 대하여 어떤 영향을 미치고, 지역별로 어떤 차이를 보이며, 그 영향이 어떻게 변화되는지를 파악하는 것이 본 연구의 목적이다. 연구목적을 달성하기 위하여 중국의 31개 성·시 패널자료를 이용하여 2SLS방법을 적용하였다. 신창타이모형(2008-2015년)과 전체기간모형(1998-2015년)으로 구분하여 분석한 결과, 신창타이모형에서 재정지출이 도시취업률에 미치는 영향이 총취업률보다 더 크고, 고소득지역에 미치는 영향이 저소득지역보다 더 크게 나타났다. 의료위생·과학기술지출은 총취업률에 긍정적 영향을 주고, 사회보장 및 취업·교육지출은 도시취업률에 긍정적 영향을 주는 것으로 나타났다. 전체기간모형에서는 재정지출이 취업에 미치는 영향패턴이 신창타이모형과 비슷하게 나타났지만 탄력성측면에서 큰 차이를보였다. 따라서 “신창타이”시대에 진입하면서 재정지출이 취업에 미치는 효과는 증가되고 있는 실정이며, 재정지출 구조의 변화를 이루어야 “신창타이”시대에 재정지출이 취업에 미치는 효율성이 증가될 수 있을 것이다. Under the new normal, the China`s economy growth has changed rapid growth to moderate growth since 2007. With new paradigm, China is facing an abnormally severe employment situation. Also the financial expenditure is an important macro adjustment method. The research analyzes both implications of financial expenditures to employment in China, and the trend of implication in different regions. The research was conducted by 2SLS method using the panel data of 31 Chinese local governments(provinces, cities, and autonomous districts) during 1998 to 2015. The main findings are as follows. In the new normal model(2008-2015), the financial expenditure to urban employment have higher effect than total employment. Also, higher income region have more positive effect than lower income region. Medical, technology expenditure have positive effect to total employment, social security, education expenditure have positive effect to urban employment. In the total model(1998-2015) have similar results with new normal model, but the elasticity is more higher than total model. Ultimately, it can be seen that the efficiency of financial expenditure is lower than new normal model. The government should improve the expenditure structure, so as to promote the effect of financial expenditure to employment in new normal economy.

중국 “신창타이” 시대의 재정지출이 취업에 미치는 영향

심권평 ( Shen Quan-ping ),김종섭 ( Kim Jong-sup ) 국제지역학회 2017 국제지역연구 Vol.21 No.2

2007년 이후 중국경제는 고속성장에서 중·고속성장으로 변화되면서 “신창타이”시대에 진입함과 더불어 경제·사회적으로 큰 변화를 나타내고 있으며 새로운 패러다임 하에 취업문제가 큰 관심을 받게 되었다. 따라서 국가경제의 발전과 조절에서 중요한 역할을 하고 있는 재정지출이 취업에 대하여 어떤 영향을 미치고, 지역별로 어떤 차이를 보이며, 그 영향이 어떻게 변화되는지를 파악하는 것이 본 연구의 목적이며, 31개 성·시 패널자료를 이용하였다. 신창타이기간(2008-2015년)과 전체기간(1998-2015년)으로 구분하여 분석한 결과, 신창타이기간에서 재정지출이 도시취업률에 미치는 영향이 총취업률보다 더 크고, 고소득지역에 미치는 영향이 저소득지역보다 더 크게 나타났다. 의료위생·과학기술지출은 총취업률에 긍정적 영향을 주고, 사회보장 및 취업·교육지출은 도시취업률에 긍정적 영향을 주는 것으로 나타났다. 전체기간에서는 재정지출이 취업에 미치는 영향패턴이 신창타이기간 분석과 비슷하게 나타났지만 탄력성측면에서 큰 차이를 보였다. 따라서 “신창타이”시대에 진입하면서 재정지출이 취업에 미치는 효과는 긍정적인 것으로 나타났다. 사회보장 및 취업·교육·의료위생·과학기술부문 지출을 확대하고 경제건설, 일반행정과 같은 지출의 감소 등 재정지출 구조를 변화시켜야 “신창타이”시대에 있어서 재정지출의 취업에 대한 효율성을 증가시킬 수 있을 것이다. Under the new normal, the China`s economy growth has changed rapid growth to moderate growth since 2007. With new paradigm, China is facing an abnormally severe employment situation. Also the financial expenditure is an important macro adjustment method. The research analyzes both implications of financial expenditures to employment in China, and the trend of implication in different regions. The research was conducted by 2SLS method using the panel data of 31 Chinese local governments(provinces, cities, and autonomous districts) during 1998 to 2015. The main findings are as follows. In the new normal model(2008-2015), the financial expenditure to urban employment have higher effect than total employment. Also, higher income region have more positive effect than lower income region. Medical, technology expenditure have positive effect to total employment, social security, education expenditure have positive effect to urban employment. In the total model(1998-2015) have similar results with new normal model, but the elasticity is more higher than total model. Ultimately, it can be seen that the efficiency of financial expenditure is lower than new normal model. The government should increase the proportion of expenditure in fields of social security, education, medical, technology, and improve the expenditure structure. So as to promote the effect of financial expenditure to employment in new normal economy.

Ginsenoside Rg1 activates ligand-independent estrogenic effects via rapid estrogen receptor signaling pathway

Quan-Gui Gao,Li-Ping Zhou,Vien Hoi-Yi Lee,Hoi-Yi Chan,Cornelia Wing-Yin Man,Man-Sau Wong 고려인삼학회 2019 Journal of Ginseng Research Vol.43 No.4

Background: Ginsenoside Rg1 was shown to exert ligand-independent activation of estrogen receptor(ER) via mitogen-activated protein kinaseemediated pathway. Our study aimed to delineate themechanisms by which Rg1 activates the rapid ER signaling pathways. Methods: ER-positive human breast cancer MCF-7 cells and ER-negative human embryonic kidneyHEK293 cells were treated with Rg1 (10 12M, 10 8M), 17ß-estradiol (10 8M), or vehicle. Immunoprecipitationwas conducted to investigate the interactions between signaling protein and ER in MCF-7 cells. To determine the roles of these signaling proteins in the actions of Rg1, small interfering RNA or theirinhibitors were applied. Results: Rg1 rapidly induced ERa translocation to plasma membrane via caveolin-1 and the formation ofsignaling complex involving linker protein (Shc), insulin-like growth factor-I receptor, modulator ofnongenomic activity of ER (MNAR), ERa, and cellular nonreceptor tyrosine kinase (c-Src) in MCF-7 cells. The induction of extracellular signal-regulated protein kinase and mitogen-activated protein kinase kinase(MEK) phosphorylation in MCF-7 cells by Rg1 was suppressed by cotreatment with small interferingRNA against these signaling proteins. The stimulatory effects of Rg1 on MEK phosphorylation in thesecells were suppressed by both PP2 (Src kinase inhibitor) and AG1478 [epidermal growth factor receptor(EGFR) inhibitor]. In addition, Rg1-induced estrogenic activities, EGFR and MEK phosphorylation in MCF-7 cells were abolished by cotreatment with G15 (G protein-coupled estrogen receptor-1 antagonist). Theincrease in intracellular cyclic AMP accumulation, but not Ca mobilization, in MCF-7 cells by Rg1 could beabolished by G15. Conclusion: Ginsenoside Rg1 exerted estrogenic actions by rapidly inducing the formation of ER containingsignalosome in MCF-7 cells. Additionally, Rg1 could activate EGFR and c-Src ER-independentlyand exert estrogenic effects via rapid activation of membrane-associated ER and G protein-coupled estrogenreceptor.

Review : Perspective on Peroral Endoscopic Myotomy for Achalasia: Zhongshan Experience

( Quan Lin Li ),( Ping Hong Zhou ) The Editorial Office of Gut and Liver 2015 Gut and Liver Vol.9 No.2

Worldwide, peroral endoscopic myotomy (POEM) has achieved remarkable initial outcomes in the treatment of achalasia. In China, POEM has developed very quickly since the first case was performed in our center in August 2010. With experience, we have successfully performed POEM for special cases (such as pediatric patients, patients with sigmoid-type esophagus, and patients with recurrent symptoms after previous surgery) and have altered our technique to achieve long-term symptom remission and simplify the POEM procedure. These changes include posterior wall incision, full-thickness myotomy, a “push-and-pull” technique for myotomy, and water-jet assisted POEM. In this article, our experiences in POEM are summarized, including changes in technique, applications of the procedure, and the management of possible complications. (Gut Liver, 2015;9:152-158)

Magnetic Properties in Iron Film System Deposited on Liquid Surfaces

Jian-Ping Xie,Quan-Lin Ye,Xiao-Jun Xu,Gao-Xiang Ye 한국자기학회 2008 한국자기학회 학술연구발표회 논문개요집 Vol.- No.-

Ginsenoside Rg1 activates ligand-independent estrogenic effects via rapid estrogen receptor signaling pathway

Gao, Quan-Gui,Zhou, Li-Ping,Lee, Vien Hoi-Yi,Chan, Hoi-Yi,Man, Cornelia Wing-Yin,Wong, Man-Sau The Korean Society of Ginseng 2019 Journal of Ginseng Research Vol.43 No.4

Background: Ginsenoside Rg1 was shown to exert ligand-independent activation of estrogen receptor (ER) via mitogen-activated protein kinase-mediated pathway. Our study aimed to delineate the mechanisms by which Rg1 activates the rapid ER signaling pathways. Methods: ER-positive human breast cancer MCF-7 cells and ER-negative human embryonic kidney HEK293 cells were treated with Rg1 ($10^{-12}M$, $10^{-8}M$), $17{\beta}$-estradiol ($10^{-8}M$), or vehicle. Immunoprecipitation was conducted to investigate the interactions between signaling protein and ER in MCF-7 cells. To determine the roles of these signaling proteins in the actions of Rg1, small interfering RNA or their inhibitors were applied. Results: Rg1 rapidly induced $ER{\alpha}$ translocation to plasma membrane via caveolin-1 and the formation of signaling complex involving linker protein (Shc), insulin-like growth factor-I receptor, modulator of nongenomic activity of ER (MNAR), $ER{\alpha}$, and cellular nonreceptor tyrosine kinase (c-Src) in MCF-7 cells. The induction of extracellular signal-regulated protein kinase and mitogen-activated protein kinase kinase (MEK) phosphorylation in MCF-7 cells by Rg1 was suppressed by cotreatment with small interfering RNA against these signaling proteins. The stimulatory effects of Rg1 on MEK phosphorylation in these cells were suppressed by both PP2 (Src kinase inhibitor) and AG1478 [epidermal growth factor receptor (EGFR) inhibitor]. In addition, Rg1-induced estrogenic activities, EGFR and MEK phosphorylation in MCF-7 cells were abolished by cotreatment with G15 (G protein-coupled estrogen receptor-1 antagonist). The increase in intracellular cyclic AMP accumulation, but not Ca mobilization, in MCF-7 cells by Rg1 could be abolished by G15. Conclusion: Ginsenoside Rg1 exerted estrogenic actions by rapidly inducing the formation of ER containing signalosome in MCF-7 cells. Additionally, Rg1 could activate EGFR and c-Src ER-independently and exert estrogenic effects via rapid activation of membrane-associated ER and G protein-coupled estrogen receptor.

On a second order parallel variable transformation approach

Li-Ping Pang,Zun-Quan Xia,Li-Wei Zhang 한국전산응용수학회 2003 Journal of applied mathematics & informatics Vol.11 No.1-2

Protective Effects of Chalcone Derivatives for Acute Liver Injury in Mice

Li-Ping Guan,Ji-Xing Nan,Xue-Jun Jin,Qing-Hao Jin,곽경철,채규윤,Zhe-Shan Quan 대한약학회 2005 Archives of Pharmacal Research Vol.28 No.1

The hepatoprotective effects of chalcone derivatives were evaluated in D-galactosamine/ lipopolysaccharide (D-GalN/LPS)-induced fulminant hepatic failure in mouse. Thirteen chalcone derivatives were synthesized for study and their hepatoprotective effects were evaluated by assessing aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels in serum. Chalcone preparations were injected into mice at 12 h and 1 h before intraperitoneal injection of D- GalN/LPS. After abdominal administration, changes in AST and ALT between the control and treated groups were observed. Ten of the synthesized chalcone derivatives exhibited inhibitory effects on D-GalN/LPS-induced levels of AST and ALT in mice. Compounds 2, 3, 8, 9, and 12 markedly reduced serum AST and ALT at 8 h, inhibited hepatocyte necrosis and showed significant hepatoprotective activities. The activity of compound 3 was compared with the bifendate (DDB) through oral administration. Compound 3 showed much higher inhibitory effects than bifendate for decreasing AST and ALT activity. The results indicate that compound 3 has strong hepatoprotective activity through suppression of tumor necrosis factoralpha (TNF-alpha) preduction, reduction of the histological change in the liver, and attenuated of hepatocyte apoptosis confirmed by DNA fragmentation assay.

Calculation of Life-Time Death Probability due Malignant Tumors Based on a Sampling Survey Area in China

Yuan, Ping,Chen, Tie-Hui,Chen, Zhong-Wu,Lin, Xiu-Quan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.10

Purpose: To calculate the probability of one person's life-time death caused by a malignant tumor and provide theoretical basis for cancer prevention. Materials and Methods: The probability of one person's death caused by a tumor was calculated by a probability additive formula and based on an abridged life table. All data for age-specific mortality were from the third retrospective investigation of death cause in China. Results: The probability of one person's death caused by malignant tumor was 18.7% calculated by the probability additive formula. On the same way, the life-time death probability caused by lung cancer, gastric cancer, liver cancer, esophageal cancer, colorectal and anal cancer were 4.47%, 3.62%, 3.25%, 2.25%, 1.11%, respectively. Conclusions: Malignant tumor is still the main cause of death in one's life time and the most common causes of cancer death were lung, gastric, liver, esophageal, colorectal and anal cancers. Targeted forms of cancer prevention and treatment strategies should be worked out to improve people's health and prolong life in China. The probability additive formula is a more scientific and objective method to calculate the probability of one person's life-time death than cumulative death probability.

Technical Note : The FasT-Fix Repair Technique for Ramp Lesion of the Medial Meniscus

( Wei Ping Li ),( Zhong Chen ),( Bin Song ),( Rui Yang ),( Wei Quan Tan ) 대한슬관절학회 2015 대한슬관절학회지 Vol.27 No.1

Introduction: This technical note describes a new arthroscopic technique to repair the peripheral attachment lesion of the posterior horn of the medial meniscus. The operation was performed under arthroscopy using a standard anterior portal. Surgical Technique: A FasT-Fix needle was inserted obliquely close to the tibial plateau and the first implant was inserted into the joint capsule depending on its bending angle underneath the meniscus. The second implant was inserted through 1/3 periphery of the meniscus into the meniscocapsular area. The pre-tied self-sliding knot was tensioned to achieve secure fixation of the posterior meniscal peripheral attachment at the original attachment point. Materials and Methods: From August 2011 to February 2014, 23 knees were diagnosed as ramp lesion, underwent meniscal repair using FasT-Fix technique. Results: All patients were followed up for average 14 months. The Lysholm score improved from preoperative 64.4±4.52 to postoperative 91.2±4.60. Conclusions: We believe that the FasT-Fix technique via the standard anterior portal can be a more convenient and less traumatic alternative for repair of the peripheral attachment lesion of the posterior horn of the medial meniscus in the anterior cruciate ligament deficient knee.