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      • KCI등재

        Studies on the influence factors of wind dynamic responses on hyperbolic cooling tower shells

        Jun-Feng Zhang,Qing-Shuai LIU,Yao-Jun Ge,Lin Zhao 국제구조공학회 2019 Structural Engineering and Mechanics, An Int'l Jou Vol.72 No.5

        Wind induced dynamic responses on hyperbolic cooling tower (HCT) shells are complicated functions of structure and wind properties, such as the fundamental frequency fmin, damping ratio ζ, wind velocity V, correlationship in meridian direction and so on, but comprehensions on the sensitivities of the dynamic responses to these four factors are still limited and disagree from each other. Following the dynamic calculation in time domain, features of dynamic effects were elaborated, focusing on the background and resonant components σB and σR, and their contributions to the total rms value σT. The σR is always less than σB when only the maximum σT along latitude is concerned and the contribution of σR to σT varies with responses and locations, but the σR couldn’t be neglected for structural design. Then, parameters of the above four factors were artificially adjusted respectively and their influences on the gust responses were illustrated. The relationships of σR and the former three factors were expressed by fitted equations which shows certain differences from the existing equations. Moreover, a new strategy for wind tunnel tests aiming at surface pressures and the following dynamic calculations, which demands less experiment equipment, was proposed according to the influence from meridian correlationship.

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        Sentinel lymph Node mapping versus systematic pelvic lymphadenectomy on the prognosis for patients with intermediate-high-risk Endometrial Cancer confined to the uterus before surgery: trial protocol for a non-inferiority randomized controlled trial (SNE

        Jun Guan,Yu Xue,Rong-yu Zang,Ji-hong Liu,Jian-qing Zhu,Ying Zheng,Bo Wang,Hua-ying Wang,Xiao-jun Chen 대한부인종양학회 2021 Journal of Gynecologic Oncology Vol.32 No.4

        Background: Sentinel lymph node (SLN) mapping has been recommended as an alternative staging approach to lymphadenectomy for apparent uterine-confined endometrial cancer (EC). However, the prognostic value of SLN mapping alone instead of systematic lymphadenectomy on EC patients remains unclear. Methods: A multi-center, open label, non-inferiority randomized controlled trial has been designed to identify if SLN mapping alone is not inferior to pelvic lymphadenectomy on prognosis of patients with intermediate-high-risk EC clinically confined to uterus. Eligible patients will be 1:1 randomly assigned to accept SLN mapping or pelvic lymphadenectomy. The primary endpoint is the 2-year progression-free survival (PFS). The second points are the 5-year PFS, 5-year overall survival, surgery-related adverse events and life quality. A total of 780 patients will be enrolled from 6 hospitals in China within 3-year period and followed up for 5 years. Trial Registration: ClinicalTrials.gov Identifier: NCT04276532

      • KCI등재

        Rapid Analysis of Melamine Content in Powdered and Liquid Milk Using Fourier Transform Infrared Spectroscopy

        Jun Wang,Soojin Jun,Qing X. Li 한국식품과학회 2009 Food Science and Biotechnology Vol.18 No.5

        Melamine is a chemical intermediate to manufacture amino resins and plastics, which cannot be used as food additive since it can cause kidney stones. A qualitative determination method of melamine residue in powdered and liquid milk was developed using Fourier transform infrared (FTIR) spectroscopic technique. The calibration sets consisted of 21 standard melamine solutions, in which 1% trichloroacetic acid aqueous solution and acetonitrile (3:1, v/v) were used as solvent. The model was validated using 10 standard melamine solutions which were unused to build up the calibration set. Infrared (IR) absorbance peaks specific to almost all chemical groups in melamine molecule were shown in the spectral range between 1,100 and 1,800/㎝. Combined partial least squares (PLS)-2<SUP>nd</SUP> derivative calibration model coupled with mean centering (MC) mathematical enhancement showed the highest correlation coefficients (R²>0.99). In brief, the FTIR technique can be used for quantitative analysis of melamine in milk samples.

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      • SCIESCOPUSKCI등재
      • KCI등재

        Lobeglitazone, A Peroxisome Proliferator-Activated Receptor-Gamma Agonist, Inhibits Papillary Thyroid Cancer Cell Migration and Invasion by Suppressing p38 MAPK Signaling Pathway

        Jun-Qing Jin,한정선,하정훈,백한상,임동준 대한내분비학회 2021 Endocrinology and metabolism Vol.36 No.5

        Background: Peroxisome proliferator-activated receptor-gamma (PPAR-γ) ligands have been widely shown to correlate with epithelial-mesenchymal transition (EMT) and cancer progression. Lobeglitazone (LGZ) is a novel ligand of PPAR-γ; and its role inEMT and metastasis in papillary thyroid carcinoma (PTC) is poorly understood. We aimed to investigate the role of LGZ in metastatic behavior of PTC cells. Methods: Half maximal inhibitory concentration (IC50) values of LGZ in BRAF-mutated PTC cell lines (BCPAP and K1) were determined using MTT assay. Rosiglitazone (RGZ), the PPAR-γ ligand was used as a positive control. The protein expression ofPPAR-γ, cell-surface proteins (E-cadherin, N-cadherin), cytoskeletal protein (Vimentin), transcription factor (Snail), p38 mitogenactivated protein kinase (MAPK), extracellular signal-regulated kinase (ERK) 1/2 pathway, and matrix metalloproteinase (MMP)-2expression were measured using Western blotting. Changes in E-cadherin expression were also determined using immunocytochemistry. Cell migration and invasion were analyzed using wound healing and Matrigel invasion assays. Results: Treatment with LGZ or RGZ significantly inhibited transforming growth factor-beta1 (TGF-β1)-induced EMT-associatedprocesses such as fibroblast-like morphological changes, EMT-related protein expression, and increased cell migration and invasionin BCPAP and K1 cells. LGZ restored TGF-β1-induced loss of E-cadherin, as observed using immunocytochemistry. Furthermore,LGZ and RGZ suppressed TGF-β1-induced MMP-2 expression and phosphorylation of p38 MAPK, but not ERK1/2. Althoughthere was no change in PPAR-γ expression after treatment with LGZ or RGZ, the effect of downstream processes mediated by LGZwas hampered by GW9662, a PPAR-γ antagonist. Conclusion: LGZ inhibits TGF-β1-induced EMT, migration, and invasion through the p38 MAPK signaling pathway in a PPAR-γ-dependent manner in PTC cells.

      • Development of Automatic Measuring System for Fish Length on Board

        ( Jun-qing Huang ),( Sin-chen Li ),( Ching-lu Hsieh ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1

        In order to meet requirement from International Organizations, each far sea vessel needs report fish length of its catch. Currently, the length is manually measured and recorded which is laborious, time consuming, and tends to manual errors. Therefore, argues occur occasionally between vessel managers and government agents. It needs new approach to improve. This study developed an automatic measuring and recording system for fish length which consists of object detecting unit, length measuring unit, guiding slider (chain type or pneumatic type), PLC (programmable logic controller), and PC (personal computer). The system detected and measured fish length, once the carried fish enter the detecting zoon on deck. Fish length was measured by sensing the signal of object existence by a sensor on the slider. The lasting time of detected object (fish) and the slider speed were multiplied to obtain fish length. This operation was processed by a computer program in Visual Basic. The length data can also be saved in a file along with date, time, and its catch position (longitude and latitude) when worked with GPS (global positioning system). The system was tested in room with four boxes of length of 37, 63, 90, and 126 cm. The accuracy in length was about 95 to 97%, according to test results. Factors influencing on the accuracy included response time of the sensor, moving speed of the slider, and the distance between sensor and object. Real fish (yellow fin tuna) samples were also tested in room and in a CT7 vessel. The length accuracy was about 90 to 95% when a modified coefficient was adopted in the computer program. Detection part of fish (such as fish back or fish abdomen), the height of sensor position, luminance of detection environment were the factors affecting the accuracy. Test result also showed the automatic system completed one reading in 3 second which reduced the time in more than 50% compared to the manual operation. Meanwhile, the system also can avoid the manual record error and work with electronic monitoring system (EMS) by sending catch data thru satellite in real time from far sea to control center on land so as to offer better quality of length data for fishery and nature resource management.

      • KCI등재
      • KCI등재

        Fermented cottonseed meal improves production performance and reduces fat deposition in broiler chickens

        Niu Jun Li,Wei Lian Qing,Luo Yuan Qing,Yang Wen Ting,Lu Qi Cheng,Zheng Xin Xia,Niu Yu Jie,Sheng Wen,Cheng Hong,Zhang Wen Ju,Nie Cun Xi 아세아·태평양축산학회 2021 Animal Bioscience Vol.34 No.4

        Objective: This study was conducted to investigate the effect of fermented cottonseed meal (FCSM) on growth performance, carcass traits, and fat deposition in white-feather broiler chickens. Methods: A total of 480 male one-day-old white-feather broiler chickens were selected randomly and divided into four groups with six replicates of 20 chickens in each. The experimental chickens were fed diets including 3%, 6%, or 9% FCSM fermented by Candida tropicalis until 42 days old. In the experiment, the chickens of the control group were fed soybean meal. Results: FCSM supplementation linearly decreased the feed conversion ratio from d 15 to 21 and d 36 to 42, respectively (p<0.05). The percentage of carcass and semi-eviscerate increased in response to dietary FCSM supplementation at d 21 (p<0.05). The percentage of eviscerated and semi-eviscerate of 3FCSM was higher than that in other groups at d 35 (p<0.05). At the age of 42 d, the percentage of carcass increased in a quadratic way among increasing FCSM in diets (p<0.05). The subcutaneous fat thickness linearly decreased with the increasing levels of FCSM at d 21 (p<0.05). Gompertz and Logistic functions provided a better fit on abdominal fat and subcutaneous fat, respectively. The best fitted equation predicted that the maximum growth rate of abdominal fat weight and subcutaneous fat thickness occurred at d 28. FCSM had no significant effects on the shape of growth curve of abdominal fat weight and subcutaneous fat thickness, but reduced the height of the curve. Birds receiving the 6FCSM diet for 21 d had smaller adipocyte surface and lower serum glucose as well as triglyceride concentration. Conclusion: FCSM is beneficial for broiler chickens as it positively affects their growth and carcass in addition to altering their fat deposition. Objective: This study was conducted to investigate the effect of fermented cottonseed meal (FCSM) on growth performance, carcass traits, and fat deposition in white-feather broiler chickens.Methods: A total of 480 male one-day-old white-feather broiler chickens were selected randomly and divided into four groups with six replicates of 20 chickens in each. The experimental chickens were fed diets including 3%, 6%, or 9% FCSM fermented by <i>Candida tropicalis</i> until 42 days old. In the experiment, the chickens of the control group were fed soybean meal.Results: FCSM supplementation linearly decreased the feed conversion ratio from d 15 to 21 and d 36 to 42, respectively (p<0.05). The percentage of carcass and semi-eviscerate increased in response to dietary FCSM supplementation at d 21 (p<0.05). The percentage of eviscerated and semi-eviscerate of 3FCSM was higher than that in other groups at d 35 (p<0.05). At the age of 42 d, the percentage of carcass increased in a quadratic way among increasing FCSM in diets (p<0.05). The subcutaneous fat thickness linearly decreased with the increasing levels of FCSM at d 21 (p<0.05). Gompertz and Logistic functions provided a better fit on abdominal fat and subcutaneous fat, respectively. The best fitted equation predicted that the maximum growth rate of abdominal fat weight and subcutaneous fat thickness occurred at d 28. FCSM had no significant effects on the shape of growth curve of abdominal fat weight and subcutaneous fat thickness, but reduced the height of the curve. Birds receiving the 6FCSM diet for 21 d had smaller adipocyte surface and lower serum glucose as well as triglyceride concentration.Conclusion: FCSM is beneficial for broiler chickens as it positively affects their growth and carcass in addition to altering their fat deposition.

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