Up-regulation of Thy-1 Promotes Invasion and Metastasis of Hepatocarcinomas

Cheng, Bian-Qiao,Jiang, Yi,Li, Dong-Liang,Fan, Jing-Jing,Ma, Ming Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4

Increasing evidence has revealed that thy-1 was a potential stem cell marker of liver cancer, but no data have been shown on how thy-1 regulates the pathophysiology of liver cancer, such as proliferation, apoptosis, invasion and migration. We previously demonstrated that thy-1 was expressed in about 1% of hepg2 cells, thy-1+hepg2 cells, but not thy-1-, demonstrating high tumorigenesis on inoculation $0.5{\times}10^5$ cells per BACA/LA mouse after 2 months. In the present study, our results showed that higher expression of thy-1 occurs in 72% (36/50 cases) of neoplastic hepatic tissues as compared to 40% (20/50 cases) of control tissues, and the expression of thy-1 is higher in poorly differentiated liver tumors than in the well-differentiated ones. In addition, thy-1 expression was detected in 85% of blood samples from liver cancer patients, but none in normal subjects or patients with cirrhosis or hepatitis. There was a significant negative correlation between thy-1expression and E-cadherin expression (a marker of invasion and migraton), but not between thy-1 expression and AFP expression in all the liver cancer and blood samples. We further investigated the relationship between thy-1 and E-cadherin in liver cancer hepg2 cell line which was transfected with pReceiver-M29/thy-1 eukaryotic expression vector followed by aspirin treatment. Lower expression of E-cadherin but higher expressions of thy-1 were detected in hepg2 cells transfected with pReceiver-M29/thy-1. Taken together, our study suggested that thy-1 probably regulates liver cancer invasion and migration.

Preparation, surface characteristic and photoactive activitiesof Ni₂FeV₃O₁₁ semiconductor nanoparticles

Qiao, X.,Yang, L.,Li, Y.,Wan, Y.,Huang, Y.,Cheng, H.,Seo, H.J. North-Holland 2016 Materials letters Vol.163 No.-

Ni<SUB>2</SUB>FeV<SUB>3</SUB>O<SUB>11</SUB> nanorods were prepared by the sol-gel method via film-coating and subsequent heating. The sample was conducted by the crystal structure refinement confirming a pure triclinic phase with space group P-1. The surface characteristics were investigated by the measurements such as scanning electron microscope (SEM), transmission electron microscopy (TEM), specific surface area, and energy-dispersive X-ray spectroscopy (EDX). The photo-physical properties of Ni<SUB>2</SUB>FeV<SUB>3</SUB>O<SUB>11</SUB> nanorods were measured by the UV-vis absorption spectrum, and the photodegradation for methylene blue solutions (MB). This vanadate semiconductor has band-gap energy of 1.85eV and presents an efficient photocatalytic activity driven by visible-light. Moreover, the nanorods are magnetically recoverable after the photocatalysis.

Visualization of Peripheral Pulmonary Artery Red Thrombi Utilizing Optical Coherence Tomography

Cheng Hong,Wei Wang,Nan-shan Zhong,Guang-qiao Zeng,Nuo-fu Zhang 대한영상의학회 2013 Korean Journal of Radiology Vol.14 No.5

Optical coherence tomography (OCT) is a new imaging technique capable of obtaining high-resolution intravascular images and has been used in interventional cardiology. However, an application of OCT in pulmonary arteries had seldom been documented. In this case, OCT imaging is performed in peripheral pulmonary arteries and shows mural red thrombi. Subsequently, the red thrombi are aspirated and confirmed by a histological examination. These findings suggest that OCT may be a useful tool to depict peripheral pulmonary artery thrombi.

Preparation and spectral characteristics of Ce3+-activated boroaluminate LaAl2B3O9

Qiao, X.,Cheng, Y.,Qin, C.,Tao, Z.,Huang, Y.,Cai, P.,Chen, C.,Seo, H. J. Springer Science + Business Media 2015 APPLIED PHYSICS A MATERIALS SCIENCE AND PROCESSING Vol.118 No.2

Coprecipitation synthesis, structure and photoluminescence properties of Eu³⁺-doped sodium barium borate

Qiao, X.,Cheng, Y.,Qin, L.,Qin, C.,Cai, P.,Kim, S.I.,Seo, H.J. Elsevier Sequoia 2014 JOURNAL OF ALLOYS AND COMPOUNDS Vol.617 No.-

Micro-sized phosphors of Eu<SUP>3+</SUP>-doped NaBaBO<SUB>3</SUB> (0.5-12mol%) were prepared by the modified co-precipitation synthesis. The samples were characterized by scanning electron micrograph (SEM) images and electron dispersive X-ray (EDX). The polycrystalline samples are well developed to the regular plate-like particles with the uniform morphology. The single crystal-phase NaBaBO<SUB>3</SUB> of the Eu<SUP>3+</SUP>-doped sample was confirmed by X-ray powder diffraction (XRD) measurements and the structure refinement. The optical properties are evaluated by photoluminescence (PL) excitation and emission spectra, and decay curves. The absolute luminescence quantum efficiency (QE) and the activation energy (ΔE) are reported. Eu<SUP>3+</SUP>-doped NaBaBO<SUB>3</SUB> presents a bright red-emitting color under the excitation of near-UV light around 400nm. The maximum absolute QE of NaBaBO<SUB>3</SUB>:Eu<SUP>3+</SUP> is estimated to be 53% at 300K. The phosphor shows an excellent thermal stability on temperature quenching effects. The results were discussed on the relationship between the structure and the luminescence properties.

Preparation, characterization and high quantum efficiency of yellow-emitting CsVO₃ nanofibers

Qiao, X.,Li, Y.,Wan, Y.,Huang, Y.,Cheng, H.,Seo, H.J. Elsevier Sequoia 2016 JOURNAL OF ALLOYS AND COMPOUNDS Vol.656 No.-

The self-activated yellow-emitting CsVO<SUB>3</SUB> nanofibers were prepared by the hydrothermal reaction method. The structural refinement was conducted on the base of XRD measurement. The surface properties of the CsVO<SUB>3</SUB> nanofibers were investigated using Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), and Energy Dispersive Spectrometry (EDS). One of the morphological characterizations is the high length-diameter ratio with diameters of 100-150 nm and lengths of tens of micrometers. The UV-vis absorption spectrum and the electronic band structures of CsVO<SUB>3</SUB> nanofiber show a direct allowed electronic gap with band energy of 2.997 eV. The luminescence properties such as photoluminescence spectra, decay lifetime, color coordinates and the absolute internal quantum efficiency (η) were studied. Notably, CsVO<SUB>3</SUB> nanofibers present a bright yellow luminescence with a high quantum efficiency of 85%. It is suggested that CsVO<SUB>3</SUB> nanofibers could be used for efficient lighting and display.

Hydrothermal synthesize and photocatalytic ability of a new silver vanadate semiconductor K_2/5Ag_3/5VO₃ with stable α-AgVO₃ structure

Qiao, Xuebin,Huang, Yanlin,Cheng, Han,Seo, Hyo Jin Elsevier 2016 Materials letters Vol.164 No.-

<P><B>Abstract</B></P> <P>A silver vanadate semiconductor K<SUB>2/5</SUB>Ag<SUB>3/5</SUB>VO<SUB>3</SUB> with the stable α-AgVO<SUB>3</SUB> structure has been prepared via the hydrothermal method. The structural refinements were completed. Similar to the well-known β-AgVO<SUB>3</SUB>, K<SUB>2/5</SUB>Ag<SUB>3/5</SUB>VO<SUB>3</SUB> also keeps one-dimensional crystallization habit with a high ratio of length to diameter. The surface was characterized by the SEM, TEM, energy dispersive spectrometer (EDS) spectrum and nitrogen adsorption–desorption isotherms. The UV–vis absorption spectrum shows that K<SUB>2/5</SUB>Ag<SUB>3/5</SUB>VO<SUB>3</SUB> nanowire has narrow band energy (2.02eV) characterized by indirect allowed electronic transition. K<SUB>2/5</SUB>Ag<SUB>3/5</SUB>VO<SUB>3</SUB> nanowires present a very good dispersion in water. Photocatalysis was tested by the photo-degradation of methylene blue (MB) solution. The textile structure of the nanowires makes recovery possible by filtering after photocatalytic reactions<B>.</B> K<SUB>2/5</SUB>Ag<SUB>3/5</SUB>VO<SUB>3</SUB> nanowires show effective photocatalytic ability under visible-light irradiation.</P> <P><B>Highlights</B></P> <P> <UL> <LI> K<SUB>2/5</SUB>Ag<SUB>3/5</SUB>VO<SUB>3</SUB> semiconductor was developed by the hydrothermal method. </LI> <LI> K<SUB>2/5</SUB>Ag<SUB>3/5</SUB>VO<SUB>3</SUB> presents stable α-AgVO<SUB>3</SUB> structure with narrow band (2.02eV). </LI> <LI> It keeps one-dimensional crystallization with a high ratio of length to diameter. </LI> <LI> The nanowires present very good dispersion in water and can be well recycled. </LI> <LI> K<SUB>2/5</SUB>Ag<SUB>3/5</SUB>VO<SUB>3</SUB> has effective photocatalytic ability under visible-light irradiation. </LI> </UL> </P>

Network Intrusion Detection Based on Directed Acyclic Graph and Belief Rule Base

Bang-Cheng Zhang,Guan-Yu Hu,Zhi-Jie Zhou,You-Min Zhang,Pei-Li Qiao,Lei-Lei Chang 한국전자통신연구원 2017 ETRI Journal Vol.39 No.4

Intrusion detection is very important for network situation awareness. While a few methods have been proposed to detect network intrusion, they cannot directly and effectively utilize semi-quantitative information consisting of expert knowledge and quantitative data. Hence, this paper proposes a new detection model based on a directed acyclic graph (DAG) and a belief rule base (BRB). In the proposed model, called DAG-BRB, the DAG is employed to construct a multi-layered BRB model that can avoid explosion of combinations of rule number because of a large number of types of intrusion. To obtain the optimal parameters of the DAG-BRB model, an improved constraint covariance matrix adaption evolution strategy (CMA-ES) is developed that can effectively solve the constraint problem in the BRB. A case study was used to test the efficiency of the proposed DAG-BRB. The results showed that compared with other detection models, the DAG-BRB model has a higher detection rate and can be used in real networks.

Water Inflow Prediction and Grouting Design for Tunnel considering Nonlinear Hydraulic Conductivity

Pan Cheng,Lianheng Zhao,Qiao Li,Liang Li,Shuoyun Zhang 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.9

Grouting prevents groundwater leakage into tunnels, based on the exponent model that expresses the nonlinear variation of the hydraulic conductivity of the surrounding rock, the formulas for predicting the magnitude of water inflow and outer water pressure of the lining after grouting are deduced. The parameter analysis shows how the water inflow decreases as the hydraulic conductivity of the grouting circle diminishes and the thickness of the grouting circle increases. When the parameter α (attenuation coefficient), which expresses the decreasing amplitude of the permeability coefficient of the surrounding rock with depth, is greater than 0, the water inflow increases until it reaches a maximum at a certain depth, and then the inflow decreases to 0 if deep enough. After considering the variation in the hydraulic conductivity of the surrounding rock, the thickness and hydraulic conductivity of the grouting circle may be designed to be too large to reduce the magnitude of the water inflow. Meanwhile, to reach the limited drainage criterion of the tunnel groundwater, the grouting circle thickness decreases gradually as α increases after the nonlinear variation of the hydraulic conductivity of the surrounding rock, which can reduce the cost for plugging the groundwater. Thus, it is critical to consider hydraulic conductivity variation during water inflow predicting and grouting when designing tunnels.

Emulsifier-Free Synthesis of Crosslinkable ABA Triblock Copolymer Nanoparticles via AGET ATRP

Chuanjie Cheng,Liang Shen,Quanlei Fu,Zhongbin Liu,Yongluo Qiao,Changqing Fu 한국고분자학회 2011 Macromolecular Research Vol.19 No.10

A crosslinkable ABA triblock copolymer was synthesized from allylic methacrylate (AMA) monomer using a poly(ethylene oxide)-based macromolecule as both an initiator and emulsifier. The “two-step” controlled/living radical polymerization can be conducted via activator generated by electron transfer (AGET) atom transfer radical polymerization (ATRP). Cheap and commercially available N,N-dimethyldodecylamine (DMDA) was found to be a good ligand for the AGET ATRP reaction. The linear ABA triblock copolymer that contains pendent allylic groups can undergo crosslinking under UV irradiation conditions, which indicates that the environmentally friendly method has potential applications in UV curing coatings and UV curing inks, etc..