Characterization of a novel variant HMW‐glutenin gene from Elymus canadensis

Qian‐Tao Jiang,Yu‐Ming Wei,Tao Liu,Ji‐Rui Wang,Zhi‐En Pu,Xiu‐Jin Lan,You‐Liang Zheng,Zhen‐Xiang Lu 한국유전학회 2010 Genes & Genomics Vol.32 No.4

High molecular weight (HMW) glutenin subunits (GS) play a key role in the determination of end‐use quality of wheat and other cereal crops. In this study, we report the isolation and characterization of both promoter region and ORF of novel HMW‐GS allele 1St1.3 from a perennial Triticeae species,Elymus canadensis. The amino acid (AA) sequences of E. canadensis 1St1.3 were deduced as 434 aa. Its protein primary structure comprises a signal peptide with a conserved N‐terminal domain, a central repetitive domain and a C‐terminal domain. E. canadensis 1St 1.3 possesses several distinct characteristics which are different from those of wheat HMW‐GSs. The N‐terminal domains of E. canadensis 1St 1.3 resemble that of y‐type subunits, while their C‐terminal domains are more similar to x‐type subunits. The deletion of 85 bp fragment has been observed in promoter region of 1St 1.3, however which has not interrupted the expression of this gene. Our results indicate that 1St 1.3 is novel HMW‐GS variants which will be valuable for enhancing our understanding of structural differentiation and the evolutionary relationship among HMW‐GSs in Triticeae species.

총성 없는 전쟁터 : 1950년대 중국에서의 북한문학 번역장

등천 ( Deng¸ Qian ) 민족문학사학회·민족문학사연구소 2020 민족문학사연구 Vol.74 No.-

본고에서는 1950년부터 1960년까지 중국에서 번역된 북한문학 작품들을 전반적으로 검토함으로써 1950년대 중국에서 북한문학 번역의 전모, 특징과 의의를 살펴보고 아울러 번역과 전쟁의 관계를 조명했다. 우선, 평화 시기와 달리 1950년대에 번역된 북한문학 작품들은 강한 시효성, 호소력과 대중성을 드러냈다. 장르별로 보면 르포르타주, 시가, 아동문학, 북한, 희곡 등을 폭넓게 번역함으로써 다양한 독자층을 최대한 포섭했다. 주제별로 보면 조선 인민의 수난과 투쟁, 미 제국주의의 침략과 폭행, 중· 조(中朝) 인민의 전우애를 형상화한 작품들을 번역함으로써 동맹국으로서의 상상된 공동체를 구축했다. 1950년대 북한문학 번역의 또 다른 특징은 동맹국 사이의 협업 번역으로 꼽힌다. 중국측에서는 일본어와 러시아어에 능통한 베테랑 번역자, 대학에 재직 중인 한인 교원, 한반도에서 귀국한 화교(華僑) 등 다양한 번역진을 조직하여 북한문학을 적극적으로 도입했다. 북한 측에서는 중국어에 능통한 번역자를 동원하여 자국문학을 계획적으로 중국에 수출했다. 6·25전쟁의 군사적 충돌과 이데올로기 간의 대치는 번역의 장에서 작용하여 문학 텍스트에 교묘하게 녹아들었다. 북한 작가 이북명의 소설 「악마」는 두 차례의 중국어 번역을 통해 각기 다른 양상으로 드러났다. 베이징 대학 한인 교원 마초군의 충실한 번역태도와 달리, 『인민문학』판 역본에는 편집자가 교묘한 첨삭을 통해 ‘사랑’과 ‘원한’의 이원적 감성 구조를 부각시키는 한편 전쟁으로 인해 조성된 부정적 감정을 대폭 은폐시켰다. 요컨대 1950년대 북한문학 번역장에서 선택과 배제, 강조와 은폐의 메커니즘이 작동하여 전쟁의 ‘실상’을 재구성하고 냉전의 심리적인 토대를 구축했다. 이런 측면에서 보면 1950년대 중국에서 활발하게 펼쳐진 북한문학 번역장은 이데올로기 투쟁의 ‘총성 없는 전쟁터’라 할 수 있다. In the early period after the foundation of the People’s Republic of China translation was institutionalized and entailed a political effect, which demonstrated in national translation program. It laid an institutional foundation for the translation of North Korean literature during the War to Resist U.S. Aggression and Aid Korea. The translation of North Korean literature in the 1950s was not only second only to Soviet literature in scale and quantity, but also reflected the publicity and propaganda function of wartime translation, thus presenting a special translation ecology. The paper, based on a survey of translation works of North Korean published in China from 1949 to 1960, through quantitative analysis and text reading, reveals three features of wartime translation. Firstly, the political orientation of the selection of source texts is prominent as well as popular. Secondly, import national translation by China and export national translation by DPRK, direct and indirect translation, foreign and local translators coexist simultaneously, which constitutes a pluralistic translation model. Thirdly, rewriting strategy is adopted to strengthen the Cold War mentality and weaken the negative emotions caused by the war, in order to demonstrate the justice of the war and prove the legitimacy of the People’s Republic of China. The authors contend that the translation of North Korean literature in the 1950’ subjectively demonstrated the wartime demands of the National Translation Program, and objectively participated in the construction of the literary genealogy of the War to Resist U.S. Aggression and Aid Korea.

How Does Power Distance Belief Impact Variety-Seeking Behavior? A Moderated Mediation Approach

Qi An,Jinzhe Yan,Yeonggil Kim The International Academy of Global Business and T 2023 The International Academy of Global Business and T Vol.19 No.6

Purpose - This research aims to enhance knowledge of variety-seeking behavior by establishing a novel antecedent based on consumer internal characteristics instead of external stimuli. The report also argues that the insights gleaned can illuminate a method to analyze consumer decision-making based on intrinsic motivation. This study evaluated a potential connection between power distance belief and variety-seeking behavior. This study evaluates variety-seeking behavior by brand, color, taste, and fashion preferences. Varietyseeking behavior is essential in understanding consumer choices. This paper aims to find the mechanism of the relation between power distance belief with variety-seeking behavior, along with the boundary condition of variety-seeking behavior. Design/Methodology/Approach - This study performed three experiments for measurement and hypothesis testing. This study employed analysis of variance, multiple regression, and process macro for moderated mediation testing with SPSS 28.0. Findings - This research confirms the prediction that higher power distance beliefs tend to elect variety through Study 1, and that risk-seeking mediates the moderation of boredom between power distance belief and variety-seeking behavior through Study 2. The authors conclude by discussing the implications for the application of the theory for managers. Research Implications - These contributions provide professionals with practical consequences for a variety of marketing tasks, such as market segmentation, product extension and innovation, and advertising guides.

Almost Sure Stability of Dual Switching Continuous-time Nonlinear System With Deterministic and Stochastic Subsystems

Qian-qian Mu,Fei Long,Qi-xiang Wang,Lang Zhang,Li-po Mo 제어·로봇·시스템학회 2024 International Journal of Control, Automation, and Vol.22 No.1

In this paper, the almost surely globally asymptotical stability and the almost surely exponential stability for dual switching continuous-time nonlinear system are investigated by using the probability analysis method and stochastic Multi-Lyapunov function, respectively. Different from the previous research results, it is the first time that dual switching continuous-time nonlinear system is used as a study object to investigate its switching stability. Then, the probability analysis method is used to overcome the deficiency that the ergodicity no longer holds due to the variable transition rate of Markov process. Some sufficient conditions for the globally asymptomatic stability almost surely and the almost surely exponential stability of dual switching continuous-time nonlinear system are given under the pre-designed deterministic switching strategy. Finally, two numerical examples are provided to verify the effectiveness of the proposed approach.

The XPD Lys751Gln Polymorphism has Predictive Value in Colorectal Cancer Patients Receiving Oxaliplatin-Based Chemotherapy: a Systemic Review and Meta-analysis

Qian, Ying-Ying,Liu, Xin-You,Pei, Dong,Xu, Jia-Li,Shen, Hua,Chen, Xiao-Feng,Liu, Yi-Qian,Shen, Li-Zong,Shu, Yong-Qian Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.22

Background: The predictive value of the xeroderma pigmentosum group D (XPD) Lys751Gln polymorphism regarding clinical outcomes of patients with colorectal cancer (CRC) receiving oxaliplatin-based chemotherapy has been evaluated in numerous published studies, but the results remain inconclusive. Therefore, we performed a meta-analysis to determine the precise role of the XPD Lys751Gln polymorphism in this clinical situation and optimize individual chemotherapy. Materials and Methods: A multiple search strategy was used to identify eligible studies. Pooled odds ratios (ORs), generalized odds ratio (ORG) and their 95% confidence intervals (CIs) were used to estimate the objective response, while hazard ratios (HRs) with 95%CIs were used for progression-free survival (PFS) and overall survival (OS). Results: A total of 17 studies including 2,286 patients met the inclusion criteria. Overall, the XPD 751Gln allele was associated with a non-significant reduced objective response to oxaliplatin-based chemotherapy in all patients or in the Asian and Caucasian subgroups. However, poor PFS and OS of CRC patients treated with oxaliplatin-based regimens were significantly related to the XPD 751Gln allele in the dominant model (PFS: HR=2.10, 95%CI: 1.65-2.67; OS: HR=3.18, 95%CI: 1.57-6.47). On stratified analysis by ethnicity, these relationships were more pronounced in Asians (PFS: HR=2.49, 95%CI: 1.79-3.47; OS: HR=5.25, 95%CI: 3.46-7.94) than in Caucasians (PFS: HR=1.73, 95%CI: 1.22-2.46; OS: HR=1.78, 95%CI: 1.06-2.99). Conclusions: The XPD Lys751Gln polymorphism may have prognostic value in patients with CRC undergoing oxaliplatin-based chemotherapy.

Highly Efficient Shoot Regeneration from Cotyledonary Nodes of Vegetable Soybean

Qian-Qian Liu,Gang Chen,Jun-Yi Gai,Yue-Lin Zhu,Li-Fei Yang,Guo-Ping Wei,Cong Wang 한국원예학회 2010 원예과학기술지 Vol.28 No.2

풋콩(Glycine max (L.) Merrill) 6개 품종의 자엽절 절편체로부터 thidiazuron(TDZ)과 NAA 농도를 달리한 배지에서 신초의 효율적인 재분화를 조사한 후, 가장 효과가 좋은 생장조절물질 조합으로 배지 종류, 접종방법 및 품종별 신초 재분화율을 조사하였다. 또한 절편체를 배지에 수직 또는 수평으로 치상하는 방법과 B5, 1/2 B5, MS, 1/2 MS, MSB(MS salts + B5 organics) 등의 5가지 기본 배지에 관하여 시험하였다. B5 배지에 1㎎?L<SUP>-1</SUP> TDZ, 0.05㎎?L<SUP>-1</SUP> NAA, 5㎎?L<SUP>-1</SUP> AgNO₃를 첨가한 처리에서 6개 품종의 신초 재분화율이 55.3-88.9%로 높았다. ‘L?ling No. 1’의 경우 수직으로 치상하는 것이 수평으로 치상하는 것보다 신초 재분화율이 37.5% 더 높았다. 따라서 풋콩은 TDZ를 처리한 B5 배지에 자엽절을 수직으로 치상할 때 신초 재분화율이 높았다. To establish a highly efficient system for shoot regeneration in vegetable soybean (Glycine max (L.) Merrill), explants were obtained from six genotypes and adventitious shoots were regenerated from cotyledonary nodes cultured on medium supplemented with different concentrations of N-phenyl-N′-1, 2, 3-thiadiazol-5-ylurea (thidiazuron TDZ) and 1-naphthylacetic acid (NAA). The most effective combination of plant growth regulators was selected first and then the effects of medium types, inoculation methods and genotypic differences on shoot regeneration were studied. The explants were inserted either vertically or horizontally into the medium and five basal media, including B5, ½ B5, MS, ½ MS, and MSB (MS salts and B5 organics), were tested. The shoot regeneration frequency of the six genotypes ranged from 53.5% to 88.9% and three of them reached 88.9%, 87.5% and 83.3%, respectively, on B5 medium supplemented with 1 ㎎?L<SUP>-1</SUP> TDZ, 0.05 ㎎?L<SUP>-1</SUP> NAA, and 5 ㎎?L<SUP>-1</SUP> AgNO₃. The shoot regeneration frequency of explants cultured on B5 medium was significantly higher than that of the other four basal media. The vertically inserted explants were found to yield a higher shoot regeneration frequency than that of horizontally inserted ones; the maximum difference of regenerating percentages between the two methods was 37.5%. In summary, TDZ was an efficient plant growth regulator for shoot induction. B5 medium and vertically inserted explants promoted shoot regeneration. We believe this highly efficient shoot regeneration system will provide foundation for the further transgenic studies in vegetable soybean.

Hepatoprotective Effects of Curcuminoids Against Oleic Acid-induced Lipid Accumulation in HepG2 Cells

Qian Qian Lee,Young Seob Lee(이영섭),Seon Min Oh(오선민),Dam Hee Kang(강담희),Da Hye Yoon(윤다혜),Doo Jin Choi(최두진),Dae Young Lee(이대영),Kyung Sook Han(한경숙),Geum Soog Kim(김금숙),Dong Hwi Kim(김동휘),Dong Yeul Kwon(권동열) 한국약용작물학회 2020 한국약용작물학회 학술대회논문집 Vol.2020 No.1

Stigma and Efficacy of Zhizhu Kuanzhong Capsules Versus Doxepin in the Treatment of Refractory Functional Dyspepsia: A Randomized Controlled Trial

Qian-Qian Wang,Li Cheng,Bi-Yu Wu,Hong-Yi Qiu,Ping Xu,Bo Wang,Xiu-Juan Yan,Sheng-Liang Chen 대한소화기 기능성질환∙운동학회 2023 Journal of Neurogastroenterology and Motility (JNM Vol.29 No.3

Background/AimsStigma related with antidepressants is prevalent in patients with functional dyspepsia. It affects medication compliance and efficacy. Herbal medicine acquired a deep-rooted cultural identity in relieving dyspeptic symptoms in Asians. The research was designed to compare the effectiveness of Zhizhu Kuanzhong capsules (ZZKZ) versus doxepin hydrochloride (doxepin) on alleviating stigma and medication nonadherence among patients with refractory FD (rFD). MethodsPatients with rFD from February 2021 to February 2022 were randomly allocated to receive either doxepin (n = 56) or ZZKZ (n = 57) combined with omeprazole for 4 weeks. Medication possession ratio (MPR), the disease- and medication-associated stigma were analyzed. The scales were utilized to assess dyspeptic symptoms (Leeds Dyspepsia Questionnaire) and psychological conditions (Generalized Anxiety Disorder Questionnaire and Patient Health Questionnaire). ResultsThe MPR values for ZZKZ were significantly higher than those for doxepin (P < 0.001). The stigma scores decreased in ZZKZ group while increased in doxepin group compared to baseline after treatment. The proportion of patients showing ZZKZ-associated stigma was significantly lower than doxepin-associated stigma (P < 0.001). The MPR values were negatively correlated with post-treatment stigma scores in both groups (P < 0.001). Dyspeptic symptoms and psychological condition were improved in both groups after treatment, with no significant difference on post-treatment Leeds Dyspepsia Questionnaire, Generalized Anxiety Disorder Questionnaire, or Patient Health Questionnaire scores between 2 groups. ConclusionZZKZ is superior to doxepin in alleviating stigma and medication non-adherence, with comparable efficacy in improving dyspeptic symptoms and psychological condition of patients with rFD.

Suppressing Erwinia carotovora Pathogenicity by Projecting N-Acyl Homoserine Lactonase onto the Surface of Pseudomonas putida Cells

( Qian Qian Li ),( Hong Ni ),( Shan Meng ),( Yan He ),( Zi Niu Yu ),( Lin Li ) 한국미생물 · 생명공학회 2011 Journal of microbiology and biotechnology Vol.21 No.12

N-Acyl homoserine lactones (AHLs) serve as the vital quorum-sensing signals that regulate the virulence of the pathogenic bacterium Erwinia carotovora. In the present study, an approach to efficiently restrain the pathogenicity of E. carotovora-induced soft rot disease is described. Bacillus thuringiensis-derived N-acyl homoserine lactonase (AiiA) was projected onto the surface of Pseudomonas putida cells, and inoculation with both strains was challenged. The previously identified N-terminal moiety of the ice nucleation protein, InaQ-N, was applied as the anchoring motif. A surface display cassette with inaQ-N/ aiiA was constructed and expressed under the control of a constitutive promoter in P. putida AB92019. Surface localization of the fusion protein was confirmed by Western blot analysis, flow cytometry, and immunofluorescence microscopy. The antagonistic activity of P. putida MB116 expressing InaQ-N/AiiA toward E. carotovora ATCC25270 was evaluated by challenge inoculation in potato slices at different ratios. The results revealed a remarkable suppressing effect on E. carotovora infection. The active component was further analyzed using different cell fractions, and the cell surface-projected fusion protein was found to correspond to the suppressing effect.

A Preventive Maintenance Scheduling Problem with Random Interval Time

Qian Qian Zhao,Won Young Yun,Alfonsus Julanto Endharta 한국경영과학회 2018 한국경영과학회 학술대회논문집 Vol.2018 No.04