Investigation on the Effect of Asymmetric Cyclic Loading on Ratcheting Deformation and Bulk Texture Development in HSLA Steel

Pushpendra Kumar Dwivedi,R. Vinjamuri,S. K. Sahoo,Krishna Dutta 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.8

Ratcheting deformation in association with bulk texture evolution in HSLA steel is studied in this investigation. The cyclicdeformation behaviors and damage modes of the specimens are obtained at room temperature, employing asymmetric stresscontrolledtests under various combinations of mean stress and stress amplitudes. Bulk texture measurements of the specimensare done adopting an X-ray diffraction analysis. The results exhibit an increase in strain accumulation from 0.23 to 30.61%associated with a sharp reduction in ratcheting life from 3320 to 880 cycles by the increment in mean stress/stress amplitude. A continuous cyclic softening until the final failure is observed for all the ratcheting tests. It is noticed that variation of meanstress is more detrimental than stress amplitude in controlling strain accumulation while the effect of stress amplitude is morepronounced than mean stress for the reduction of ratcheting life. The fracture surface morphology indicates typical striationformation in the crack propagation region along with overload failure. The bulk texture studies indicate that there is a transitionbetween ‘ϒ’ fiber and ‘ζ’ fiber during all loading conditions. The texture intensity is increased from 5.71 to 11.68 withprogressive ratcheting strain accumulation. Here also, influence of stress amplitude is more significant than the mean stress.

A Review on Venom Enzymes Neutralizing Ability of Secondary Metabolites from Medicinal Plants

Pushpendra Singh,Mohammad Yasir,Risha Hazarika,Sunisha Sugunan,Rahul Shrivastava 대한약침학회 2017 Journal of pharmacopuncture Vol.20 No.3

Objectives: Medicinal plants are vital sources of bioactive compounds that are useful for the treatment of patients with snake bites or are indirectly applicable for boosting the effects of conventional serum therapy. These plants are being used traditionally by local healers and tribes for the treatment of patients with snake bites and therefore can be used as an alternative against snake envenomation. Scientifically, using the secondary metabolites of plants to neutralize venom enzymes has an extra benefit of being based on traditional knowledge; also, the use of such metabolites for the treatment of patients with snake bites is cheaper and the treatment can be started sooner. Methods: All the available information on various secondary metabolites exhibiting venom neutralizing ability were collected via electronic search (using Google books, Pubmed, SciFinder, Scirus, Google Scholar, and Web of Science) and articles of peer-reviewed journals. Results: Recent interest in different plant has focused on isolating and identifying of different phytoconstituents that exhibit Phospholipase A2 activity and other venom enzyme neutralizing ability. In this support convincing evidence in experimental animal models are available. Conclusion: Secondary metabolites are naturally present, have no side effect, are stable for a long time, can be easily stored, and can neutralize a wide range of snake enzymes, such as phospholipase A2, hyaluronidase, protease, L-amino acid oxidase, 5’nucleotidase, etc. The current review presents a compilation of important plant secondary metabolites that are effective against snake venom due to enzyme neutralization.

Effects of carbamate pesticides intermediates on Escherichia coli membrane architecture: An in vitro and in silico approach

Pushpendra Singh,Manish Kumar Tripathi,Mohammad Yasir,Ashish Ranjan,Rahul Shrivastava 환경독성보건학회 2021 환경독성보건학회지 Vol.36 No.3

Methyl isocyanate (MIC), a low molecular weight synthetic aliphatic compound, having an isocyanate group (−NCO), has industrial application. In this study, the effects of methyl isocyanate and its mechanism on outer membrane protein of Escherichia coli were observed using experimental and computational methods. In vitro exposure of N-succinimidyl N-methylcarbamate (NSNM) a synthetic analogue of MIC on E. coli to a final concentration of 2 mM was found to affect the growth curve pattern and changes in cell morphology. Molecular docking studies of MIC and NSNM with E. coli outer membrane protein (OmpW, OmpX, OmpF OmpA), and periplasmic domain (PAL) were performed. The in-silico results revealed that outer membrane protein OmpF showed the highest negative binding energy, i.e. ΔG -4.11 kcal/mole and ΔG -3.19 kcal/mole by NSNM and MIC as compared to other proteins. Our study concludes that methyl isocyanate retains lethal toxicity which leads to cell death due to the membrane protein damage of E. coli membrane.

Multi-objective optimization of electric-discharge machining process using controlled elitist NSGA-II

Pushpendra S. Bharti,S. Maheshwari,C. Sharma 대한기계학회 2012 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.26 No.6

Parametric optimization of electric discharge machining (EDM) process is a multi-objective optimization task. In general, no single combination of input parameters can provide the best cutting speed and the best surface finish simultaneously. Genetic algorithm has been proven as one of the most popular multi-objective optimization techniques for the parametric optimization of EDM process. In this work, controlled elitist non-dominated sorting genetic algorithm has been used to optimize the process. Experiments have been carried out on die-sinking EDM by taking Inconel 718 as work piece and copper as tool electrode. Artificial neural network (ANN) with back propagation algorithm has been used to model EDM process. ANN has been trained with the experimental data set. Controlled elitist non-dominated sorting genetic algorithm has been employed in the trained network and a set of pareto-optimal solutions is obtained.

Progress in hybrid greenhouse solar dryer (HGSD): A review

Singh, Pushpendra,Gaur, Manoj K.,Kushwah, Anand,Tiwari, G.N. Techno-Press 2019 Advances in energy research Vol.6 No.2

The world population reaches to about 7.7 billion in 2018 from 6.2 billion in 2000. This much growth in population results in increased energy demand and increased food supply. As the conventional energy sources are limited. These may deplete soon if consumed at this rate. So, the world is switching towards the utilization of non-conventional sources of energy. Energy from sun is the best method as it can not only solve the energy issue but also helps in meeting food demand by conserving it. Greenhouses are made for the purpose of food conservation. Various types of solar dryers are developed by researchers till now and still the effort is being putted to make them more efficient. Hybrid greenhouse is also effort toward utilization of solar energy in more efficient way. The paper presents the heat and mass transfer analysis of hybrid greenhouse solar dryer developed by different researchers till now. The review helps the researcher in understanding the heat and mass transfer taking place inside the hybrid greenhouse and how it can be further improved.

A Review on Venom Enzymes Neutralizing Ability of Secondary Metabolites from Medicinal Plants

Singh, Pushpendra,Yasir, Mohammad,Hazarika, Risha,Sugunan, Sunisha,Shrivastava, Rahul KOREAN PHARMACOPUNCTURE INSTITUTE 2017 Journal of pharmacopuncture Vol.20 No.3

Objectives: Medicinal plants are vital sources of bioactive compounds that are useful for the treatment of patients with snake bites or are indirectly applicable for boosting the effects of conventional serum therapy. These plants are being used traditionally by local healers and tribes for the treatment of patients with snake bites and therefore can be used as an alternative against snake envenomation. Scientifically, using the secondary metabolites of plants to neutralize venom enzymes has an extra benefit of being based on traditional knowledge; also, the use of such metabolites for the treatment of patients with snake bites is cheaper and the treatment can be started sooner. Methods: All the available information on various secondary metabolites exhibiting venom neutralizing ability were collected via electronic search (using Google books, Pubmed, SciFinder, Scirus, Google Scholar, and Web of Science) and articles of peer-reviewed journals. Results:Recent interest in different plant has focused on isolating and identifying of different phytoconstituents that exhibit Phospholipase A2 activity and other venom enzyme neutralizing ability. In this support convincing evidence in experimental animal models are available. Conclusion: Secondary metabolites are naturally present, have no side effect, are stable for a long time, can be easily stored, and can neutralize a wide range of snake enzymes, such as phospholipase A2, hyaluronidase, protease, L-amino acid oxidase, 5'nucleotidase, etc. The current review presents a compilation of important plant secondary metabolites that are effective against snake venom due to enzyme neutralization.

How emotionally intelligent employees manage their internal employability through role-based job crafting? – evidence from public sector enterprises

Sameer Sanjeet Kumar,Priyadarshi Pushpendra 한국행정학회 2023 International Review of Public Administration Vol.28 No.3

Acknowledging the relevance of work environment in influencing job-related choices, this paper examines the relationship between emotional intelligence, role-based job crafting i.e. task, relational and cognitive crafting, job autonomy and internal employability. The role of job autonmy as a moderator and role-based job crafting as mediator between emotional intelligence and internal employability has also been examined. The study was conducted on 296 managers working in Indian public sector enterprises and found interesting findings including a positive and direct effect of emotional intelligence on all three forms of role-based job crafting and internal employability. The results for mediation effect of job crafting and moderation effect of job autonomy varied depending upon the form of role-based job crafting. The paper discusses theoretical implications and practical relevance of these findings and may provide a direction for interlinking job demands-resources and conservation of resource theories.

PCR-SSCP of Serum Lysozyme Gene (Exon-III) in Riverine Buffalo and Its Association with Lysozyme Activity and Somatic Cell Count

Sahoo, Nihar Ranjan,Kumar, Pushpendra,Bhushan, Bharat,Bhattacharya, T.K.,Sharma, Arjava,Dayal, Sanker,Pankaj, Prabhat Kumar,Sahoo, Monalisa Asian Australasian Association of Animal Productio 2010 Animal Bioscience Vol.23 No.8

Serum lysozyme gene is one of the important genes influencing the immune system as its product can cause lysis of bacterial cell wall by cleaving the peptidoglycan layer. The present investigation on the serum lysozyme gene of Indian riverine buffalo was undertaken with the objectives to identify and characterize single nucleotide polymorphic patterns by PCR-SSCP method as well as to study the effect of different genotypes on serum lysozyme activity and somatic cell count. A total of 280 animals comprising four different famous bubaline breeds (Murrah, Mehsana, Surti and Bhadawari), spread over six different farms across the country were used for this study. A 276 bp (partial intron 2, complete exon 3 and partial intron 3) fragment of lysozyme gene was screened for polymorphism using the SSCP technique. Four genotypes namely AA, AB, BC and AC were observed, out of which BC genotype was found to be the most frequent. Among these three alleles, C allele (0.38) was most prevalent in these populations. Various SSCP allelic variants were cloned for sequencing and sequences were submitted to NCBI Genbank. From the alignment of the nucleotide sequences of various allelic variants, it was found that there were differences in 12 positions among the alleles, out of which maximum variation (at 8 places) was found in the intronic region. The allele A was closer to allele-C than allele-B. Allele B was phylogenetically equidistant from both of the other alleles. Mean lysozyme activity determined in serum samples of different animals of Murrah buffalo was $27.35{\pm}2.42\;{\mu}g$ per ml of serum, whereas the mean somatic cell count was $1.25{\pm}0.13{\times}10^5$ cells per ml of milk. The SSCP pattern-wise effects of various genotypes on lysozyme activity and SCC were analyzed. Although the mean values were apparently different in various genotypes, these differences were statistically non-significant. It can be concluded that the riverine buffaloes are sufficiently polymorphic with respect to serum lysozyme gene. The absence of AA genotype in Bhadawari breed of buffalo can be considered as a marker for breed characterization. The difference of four nucleotides in exon-3 indicates high selection pressure on the gene.

Interplay of organizational identification, regulatory focused job crafting and job satisfaction in management of emerging job demands: evidence from public sector enterprises

Sanjeet Kumar Sameer,Pushpendra Priyadarshi 한국행정학회 2021 International Review of Public Administration Vol.26 No.1

Public sector enterprises (PSEs) face market complexities like any other commercial organization. To ensure sustenance of such enterprises, effective management of emerging job demands by their employees is crucial. Acknowledging relevance of this issue, the present study examines the role of employees’ organizational identification, as a job resource, in promotion- and preventionfocused job crafting and its effect on job satisfaction, by applying job demands-resources and regulatory focus theories. Data collected through survey questionnaire from 433 executives of public sector energy companies of India were analyzed to test hypotheses. The study found a positive effect of organizational identification on promotion- and prevention-focused job crafting and job satisfaction. Promotion-focused job crafting partially mediated the relationship of organizational identification and job satisfaction unlike prevention-focused job crafting. These unique findings may be useful from the perspective of effective job demands-resources management in a dynamic and complex operating environment of PSEs. Theoretical contributions and practical implications have been discussed.

The double burden of malnutrition among adults in India: evidence from the National Family Health Survey-4 (2015-16)

Mili Dutta,Y Selvamani,Pushpendra Singh,Lokender Prashad 한국역학회 2019 Epidemiology and Health Vol.41 No.-

OBJECTIVES: India still faces the burden of undernutrition and communicable diseases, and the prevalence of overweight/obesity is steadily increasing. The discourse regarding the dual burden of underweight and overweight/obesity has not yet been widely explored in both men and women. The present study assessed the determinants of underweight and overweight/obesity in India among adult men and women aged 15-49. METHODS: Population-based cross-sectional and nationally representative data from the National Family Health Survey-4 (2015-16), consisting of a sample of men and women, were analyzed. Stratified 2-stage sampling was used in the NFHS-4 study protocol. In the present study, bivariate and adjusted multinomial logistic regression analyses were performed to determine the correlates of underweight and overweight/obesity. RESULTS: The results suggested a persistently high prevalence of underweight coexisting with an increased prevalence of overweight/obesity in India. The risk of underweight was highest in the central and western regions and was also relatively high among those who used either smoking or smokeless tobacco. Overweight/obesity was more prevalent in urban areas, in the southern region, and among adults aged 35-49. Furthermore, level of education and wealth index were positively associated with overweight/obesity. More educated and wealthier adults were less likely to be underweight. CONCLUSIONS: In India, underweight has been prevalent, and the prevalence of overweight/obesity is increasing rapidly, particularly among men. The dual burden of underweight and overweight/obesity is alarming and needs to be considered; public health measures to address this situation must also be adopted through policy initiatives.