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Pradyumna Raval,Alistair I.W. Mayne,Phey Ming Yeap,Thomas Barry Oliver,Arpit Jariwala,Sankar Sripada 대한고관절학회 2019 Hip and Pelvis Vol.31 No.1
Purpose: Occult hip fractures in the elderly can be missed on standard radiographs and are a known cause of morbidity. These are generally diagnosed on either magnetic resonance imaging (MRI) or computed tomography scan, depending upon local hospital policy. While there is an abundance of literature on hip fractures in general, little is known about the clinical outcome of patients with occult hip fractures. The aim of this study was to review the demographics, injury characteristics, management and clinical outcome of patients diagnosed with occult femoral neck fractures on MRI. Materials and Methods: Using an existing hospital database, a retrospective analysis of all patients with occult hip fractures diagnosed by MRI scan from 2005 to 2014 was conducted. Results: Sixty-four patients (23 males and 41 females) were included. The mean duration of hospitalisation was 16 days. A significantly higher percentage of patients were discharged to their pre-existing residence compared to National Institute for Health and Care Excellence (NICE) commissioning guidelines (66% vs. 45%). The 30-and 60-day mortalities were 3% and 10%, respectively. Mortality was lower in patients who underwent internal fixation (n=3/31) compared with those undergoing replacement (hemi/total hip arthroplasty) (n=5/12) (P=0.056). Conclusion: Patients with occult hip fractures diagnosed on an MRI scan are more likely to be discharged to their pre-existing residence and have lower mortality rates compared to NICE guidelines and National Hip Fracture Database (NHFD).
Pradyumna Agasthi,Sai Harika Pujari,Farouk Mookadam,Andrew Tseng,Nithin R. Venepally,Panwen Wang,Mohamed Allam,John Sweeney,Mackram Eleid,Floyd David Fortuin,David R. Holmes Jr,Nirat Beohar,Reza Arsan 연세대학교의과대학 2020 Yonsei medical journal Vol.61 No.6
Purpose: Cardiac power (CP) index is a product of mean arterial pressure (MAP) and cardiac output (CO). In aortic stenosis, however, MAP is not reflective of true left ventricular (LV) afterload. We evaluated the utility of a gradient-adjusted CP (GCP) index in predicting survival after transcatheter aortic valve replacement (TAVR), compared to CP alone. Materials and Methods: We included 975 patients who underwent TAVR with 1 year of follow-up. CP was calculated as (CO×MAP)/[451×body surface area (BSA)] (W/m2). GCP was calculated using augmented MAP by adding aortic valve mean gradient (AVMG) to systolic blood pressure (CP1), adding aortic valve maximal instantaneous gradient to systolic blood pressure (CP2), and adding AVMG to MAP (CP3). A multivariate Cox regression analysis was performed adjusting for baseline covariates. Receiver operator curves (ROC) for CP and GCP were calculated to predict survival after TAVR. Results: The mortality rate at 1 year was 16%. The mean age and AVMG of the survivors were 81±9 years and 43±4 mm Hg versus 80±9 years and 42±13 mm Hg in the deceased group. The proportions of female patients were similar in both groups (p=0.7). Both CP and GCP were independently associated with survival at 1 year. The area under ROCs for CP, CP1, CP2, and CP3 were 0.67 [95% confidence interval (CI), 0.62–0.72], 0.65 (95% CI, 0.60–0.70), 0.66 (95% CI, 0.61–0.71), and 0.63 (95% CI 0.58–0.68), respectively. Conclusion: GCP did not improve the accuracy of predicting survival post TAVR at 1 year, compared to CP alone.
Sahoo, Pradyumna Kumar,Jana, Debarshi,Mandal, Palash Kumar,Basak, Samindranath Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15
Background: Invasion of breast cancer cells into blood and lymphatic vessels is one of the most important steps for metastasis. In this study the prognostic relevance of lymphangiogenesis and lymphovascular invasion (LVI) in breast cancer patients was evaluated in terms of survival. Materials and Methods: This retrospective study concerned 518 breast cancer patients who were treated at Department of Surgical Oncology, Saroj Gupta Cancer Centre and Research Institute, Kolkata-700063, West Bengal, India, a reputed cancer centre and research institute of eastern India between January 2006 and December 2007. Results: The median overall survival and disease free survival of the patients were 60 months and 54 months respectively. As per Log-rank test, poor overall as well as disease free survival pattern was observed for LVI positive patients as compared with LVI negative patients (p<0.01). Also poor overall as well as disease free survival pattern was observed for perineural invasion (PNI) positive patients as compared to PNI negative patients (p<0.01). Conclusions: From this study it is evident that LVI and PNI are strongly associated with outcome in terms of disease free as well as overall survival in breast cancer patients. Thus LVI and PNI constitute potential targets for treatment of breast cancer patients. We advocate incorporating their status into breast cancer staging systems.
Pairaiturkar, Pradyumna Purushottam,Sudame, Onkar Shekhar,Pophale, Chetan Shashikant The Korean Neurosurgical Society 2019 Journal of Korean neurosurgical society Vol.62 No.4
Objective : To evaluate 3-dimensional magnetic resonance imaging (MRI) of Kambin's safe zone to calculate maximum cannula diameter permissible for safe percutaneous endoscopic lumbar discectomy. Methods : Fifty 3D MRIs of 19 males and 31 females (mean, 47 years) were analysed. Oblique, axial and sagittal views were used for image analysis. Three authors calculated the inscribed circle (cannula diameter) individually, within the neural (original) and bony Kambin's triangle in oblique views, disc heights on sagittal views and root to facet distances at upper and lower end plate levels on axial views and their averages were taken. Results : The mean root to facet distances at upper end plate level measured on axial sections increased from $3.42{\pm}3.01mm$ at L12 level to $4.57{\pm}2.49mm$ at L5S1 level. The mean root to facet distances at lower end plate level measured on axial sections also increased from $6.07{\pm}1.13mm$ at L12 level to $12.9{\pm}2.83mm$ at L5S1 level. Mean maximum cannula diameter permissible through the neural Kambin's triangle increased from $5.67{\pm}1.38mm$ at L12 level to $9.7{\pm}3.82mm$ at L5S1 level. The mean maximum cannula diameter permissible through the bony Kambin's triangle also increased from $4.03{\pm}1.08mm$ at L12 level to $6.11{\pm}1mm$ at L5S1 level. Only 2% of the 427 bony Kambin's triangles could accommodate a cannula diameter of 8mm. The base of the bony Kambin's triangle taken in oblique view (3D MRI) was significantly higher than the root to facet distance at lower end plate level taken in axial view. Conclusion : The largest mean diameter of endoscopic cannula passable through "bony" Kambin's triangle was distinctively smaller than the largest mean diameter of endoscopic cannula passable through "neural" Kambin's triangle at all levels. Although proximity of exiting root to the facet joint is always taken into consideration before PELD procedure, our 3D MRI based anatomical study is the first to provide actual maximum cannula dimensions permissible in this region.
T. K. Pradyumna,Kangcheol Cho,Minseong Kim,Woojin Choi 전력전자학회 2022 JOURNAL OF POWER ELECTRONICS Vol.22 No.5
Battery capacity is a parameter that has a very close association with the state of health (SoH) of a Li-ion battery. Due to the complex electrochemical mechanisms behind the degradation of battery life, the estimation of SoH encounters many difficulties. To date, experiment-based methods, model-based methods, and data-driven models have been developed to estimate capacity using data from charging curves. In the case of EVs and HEVs, due to the unpredictable charge patterns employed by users, it is not known how much charging data will be available to predict the capacity at a given point in time. This paper presents a method to accurately estimate capacity using impedance curves obtained from an electrochemical impedance spectroscopy (EIS) test and a convolutional neural network (CNN). The CNN model was trained using the impedance data of a single cell collected at different SoH values, and the trained model was verified using the impedance data of eight other cells. The maximum error in the prediction was found to be 0.57 (% capacity) and the RMS error was found to be 0.233 (% capacity). These results illustrate the accuracy and robustness of the proposed model.
Atul Bhattad,JAHAR SARKAR,Pradyumna Ghosh 대한설비공학회 2018 International Journal Of Air-Conditioning and Refr Vol.26 No.1
Energy and economic analyses of corrugated plate evaporator have been performed in this study by using brine-based hybrid nanofluids as secondary refrigerant for low temperature applications (milk chilling, ice making and fish freezing). Various hybrid nanofluids containing alumina with different nanoparticles (copper, silver and multi walled carbon nanotube) dispersed in ethylene glycol/water, propylene glycol/water, calcium chloride/water and potassium acetate/water brines have been considered. A comparison has been made based on overall heat transfer coefficient, evaporator size (heat transfer area), pump work, COP, annual cost and payback period. The maximum reduction in heat transfer area has been observed for PG brine-based alumina–silver hybrid nanofluid. Whereas, the maximum reduction in pump work and augmentation in COP have been obtained for PG brine-based alumina–MWCNT hybrid nanofluid. EG brine-based Alumina–Cu hybrid nanofluid yields minimum annual cost. Most of the nanofluids (except PG brine-based Al2O3–Ag nanofluid) seem to be not beneficial for practical use due to comparatively long payback period; however, that can be significantly reduced in future by decreasing nanoparticle cost and increasing nanofluid stability. The present study reveals that the brine-based hybrid nanofluids may be the potential option as next generation secondary refrigerants for low temperature applications.