Possible Epithelial Ovarian Cancer Association with HPV18 or HPV33 Infection

Zhang, Pei-Pei,Zhou, Lei,Cao, Jia-Shi,Li, Yi-Ping,Zeng, Zhi,Sun, Ni,Shen, Li,Zhu, Hao-Yue,Ruan, Yang,Zha, Wen-Ting,Wang, Xin-Yu,Zhang, Ke-Qiang,Zhang, Ran Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.6

The present study was conducted to investigate the prevalence of HPV infection in epithelial ovarian cancer (EOC) in Hunan province. DNA samples were collected from paraffin embedded ovarian tissue from 322 patients with EOC, 99 with ovarian benign tumors and 199 normal persons. The polymerase chain reaction and direct sequencing were used to identify the HPV types in the samples. The relationship between the infection of human papillomavirus (HPV) and the epithelial ovarian carcinoma (EOC) was investigated combined with clinical data. The prevalence of HPV18 and HPV33 in EOC group and benign group was higher than in the normal group. HPV18 and HPV33 may play a role in the development of both EOC and ovarian benign tumor and may participate in the development of EOC with traditional risk factors, family history and abortion, possibly exerting synergistic effects.

從簡帛符號看古今人在標點方面的不同觀念

沈培(Shen Pei) 중국문화연구학회 2006 중국문화연구 Vol.0 No.9

죽간과 비단에 쓰인 문장 중간에 쓰인 부호들이 적지 않다. 지금 현대인의 시각에 서 보면, 어떤 곳은 표점부호를 사용할 필요가 없고, 어떤 곳은 표점부호를 사용할 없다. 필자는 현대인이 문장부호를 보는 태도로 이런 부호들을 이해해서는 안 된다는 점을 설명하고자 한다. 고대인이 사용한 이런 부호들은 말할 때 멈춤을 표시하기 위해서 사용하였고, 때때로 동시에 강조를 표시하거나 잘못 읽을 수 있는 부분을 표시하기 위해서 사용한 것이다.

Antibacterial and Antitumor Macrolides from Streptomyces sp. Ls9131

Pei-Ji Zhao,Li-Ming Fan,Guo-Hong Li,Na Zhu,Yue-Mao Shen 대한약학회 2005 Archives of Pharmacal Research Vol.28 No.11

Four compounds, including two novel macrolides, were isolated from an endophyte Streptomyces sp. ls9131 of Maytenus hookeri. Spectral data indicated that these compounds were dimeric dinactin (1), dimeric nonactin (2), cyclo-homononactic acid (3), and cyclo-nonactic acid (4). Bioassay results showed that dimeric dinactin had strong antineoplastic activity and antibacterial activity.

Numerical modelling of a shear-thickening fluid damper using optimal transit parameters

Pei-Ching Chen,Chung-Han Yu,Yohanes K. Surjanto,Shen-Kai Peng,Kuo-Chun Chang 국제구조공학회 2022 Smart Structures and Systems, An International Jou Vol.30 No.5

The viscosity of a shear-thickening fluid damper (STFD) can increase dramatically when the STFD undergoes highrate of excitation. Therefore, accurate numerical modelling of the STFD has been considered difficult due to this distinct feature. This study aims to develop a numerical model to accurately simulate the response of the STFD. First, a STFD is designed, fabricated, and installed in the laboratory. Then, performance tests are conducted in which sine waves with nine frequencies at three amplitude levels are adopted as the displacement excitations to the STFD. A novel numerical model which contains two parameter sets of the discrete Bouc-Wen model as well as two parameters for transiting the two parameter sets. Therefore, a total number of eighteen parameters need to be identified in the damper model. The symbiotic organisms search is applied to optimize the parameters. Numerical simulation results demonstrate that the proposed STFD model with transit parameter sets outperforms the conventional discrete Bouc-Wen model. The proposed STFD model can be applied to analyses of structures in which STFDs are installed in the future.

3-Deazaneplanocin A is a Promising Therapeutic Agent for Ovarian Cancer Cells

Shen, Liang,Cui, Jing,Pang, Ying-Xin,Ma, Yan-Hui,Liu, Pei-Shu Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.5

Background: Recent studies have shown that 3-deazaneplanocin A (DZNep), a well-known histone methyltransferase inhibitor, disrupts polycomb-repressive complex 2 (PRC2), and induces apoptosis, while inhibiting proliferation and metastasis, in cancer cells, including acute myeloid leukemia, breast cancer and glioblastoma. However, little is known about effects of DZNep on ovarian cancer cells. Materials and Methods: We here therefore studied DZNep-treated A2780 ovarian cancer cells in vitro. Proliferation of ovarian cancer cells under treatment of DZNep was assessed by MTT and apoptosis by flow cytometry. Cell wound healing was applied to detect the migration. Finally, we used q-PCR to assess the migration-related gene, E-cadherin. Results: DZNep could inhibit the proliferation of A2780 and induce apoptosis Furthermore, it inhibited migration and increased the expression of E-cadherin (P<0.05). Conclusion: DZNep is a promising therapeutic agent for ovarian cancer cells, with potential to inhibite proliferation, induce apoptosis and decrease migration.

독곽점초간차기사칙(讀郭店楚簡箚記四則)

심배 중국어문학회 2001 中國語文學誌 Vol.9 No.-

본 논문은 필자가 $lt;郭店楚幕竹簡$gt; 을 읽으며 쓴 答記이다. 첫째, $lt;五行$gt;편의 $quot;淸$quot;자는 古書의 관련된 문장과 대비해보았을 때 簡文과 馬王堆 帛書本 $lt;五行$gt; 의 $quot;晴$quot;과 같이 $quot;淸楚$quot; , $quot;淸晳$quot;의 $quot;淸$quot;으로 읽어야한다. 혹자가 이들를 모두 $quot;精$quot;으로 읽는 것은 합당하지 않다. 두번째,$lt;成之聞之$gt; 편의 $quot;成言$quot;을 $quot;盛言$quot; 으로 읽는 것은 옳지 않다. $quot;成言$quot;은 $quot;成基要約之言$quot;의 뜻이다. 셋째, $lt;六德$gt; 편의 $quot;爾$quot;자는 허사이며 $quot;也$quot;에 해당한다. 넷째, $lt;六德$gt; 편의 $quot;多$quot;는 $quot;과$quot; 혹은 $quot;可$quot;의 음을 가지고 있으므로 $quot;何$quot;와 통용할수 있으며, $quot;爲什마$quot;의 뜻을 나타낸다.

Influence of Curcumin on HOTAIR-Mediated Migration of Human Renal Cell Carcinoma Cells

Pei, Chang-Song,Wu, Hong-Yan,Fan, Fan-Tian,Wu, Yi,Shen, Cun-Si,Pan, Li-Qun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.10

Background: This study investigated the influence of curcumin on HOX transcript antisense RNA (HOTAIR)-mediated migration of cultured renal cell carcinoma (RCC) cells. Materials and Methods: Five RCC cell lines (769-P, 769-P-vector, 769-P-HOTAIR, 786-0, and Kert-3 ) were maintained in vitro. The expression of HOTAIR mRNA was determined by quantitative real-time PCR and cell migration was measured by transwell migration assay. The effects of different concentrations of curcumin (0 to $80{\mu}mol/L$) on cell proliferation was determined by the CCK-8 assay and influence of non-toxic levels (0 to $10{\mu}M$) on the migration of RCC cells was also determined. Results: Comparison of the 5 cell lines indicated a correlation between HOTAIR mRNA expression and cell migration. In particular, the migration of 769-P-HOTAIR cells was significantly higher than that of 769-P-vector cells. Curcumin at $2.5-10{\mu}M$ had no evident toxicity against RCC cells, but inhibited cell migration in a concentration-dependent manner. Conclusions: HOTAIR expression is correlated with the migration of RCC cells, and HOTAIR may be involved in the curcumin-induced inhibition of RCC metastasis.

Antibacterial and Antitumor Macrolides from Streptomyces sp. Is9131

Zhao Pei-Ji,Fan Li-Ming,Li Guo-Hong,Zhu Na,Shen Yue-Mao The Pharmaceutical Society of Korea 2005 Archives of Pharmacal Research Vol.28 No.11

Four compounds, including two novel macrolides, were isolated from an endophyte Streptomyces sp. Is9131 of Maytenus hookeri. Spectral data indicated that these compounds were dimeric dinactin (1), dimeric nonactin (2), cyclo-homononactic acid (3), and cyclo-nonactic acid (4). Bioassay results showed that dimeric dinactin had strong antineoplastic activity and antibacterial activity.

Optimal Blood Suppression Inversion Time Based on Breathing Rates and Heart Rates to Improve Renal Artery Visibility in Spatial Labeling with Multiple Inversion Pulses: A Preliminary Study

Yigang Pei,Fang Li,Hao Shen,Xueying Long,Hui Liu,Xiaoyi Wang,Jinkang Liu,Wenzheng Li 대한영상의학회 2016 Korean Journal of Radiology Vol.17 No.1

Objective: To determine whether an optimal blood suppression inversion time (BSP TI) can boost arterial visibility and whether the optimal BSP TI is related to breathing rate (BR) and heart rate (HR) for hypertension subjects in spatial labeling with multiple inversion pulses (SLEEK). Materials and Methods: This prospective study included 10 volunteers and 93 consecutive hypertension patients who had undergone SLEEK at 1.5T MRI system. Firstly, suitable BSP TIs for displaying clearly renal artery were determined in 10 volunteers. Secondly, non-contrast enhanced magnetic resonance angiography with the suitable BSP TIs were performed on those hypertension patients. Then, renal artery was evaluated and an optimal BSP TI to increase arterial visibility was determined for each patient. Patients’ BRs and HRs were recorded and their relationships with the optimal BSP TI were analyzed. Results: The optimal BSP TI was negatively correlated with BR (r1 = -0.536, P1 < 0.001; and r2 = -0.535, P2 < 0.001) and HR (r1 = -0.432, P1 = 0.001; and r2 = -0.419, P2 = 0.001) for 2 readers (κ = 0.93). For improving renal arterial visibility, BSP TI = 800 ms could be applied as the optimal BSP TI when the 95% confidence interval were 17–19/min (BR1) and 74–82 bpm (HR1) for reader#1 and 17–19/min (BR2) and 74–83 bpm (HR2) for reader#2; BSP TI = 1100 ms while 14–15/min (BR1, 2) and 71–76 bpm (HR1, 2) for both readers; and BSP TI = 1400 ms when 13–16/min (BR1) and 63–68 bpm (HR1) for reader#1 and 14–15/min (BR2) and 64–70 bpm (HR2) for reader#2. Conclusion: In SLEEK, BSP TI is affected by patients’ BRs and HRs. Adopting the optimal BSP TI based on BR and HR can improve the renal arterial visibility and consequently the working efficiency.

Low-voltage blue light emission from n-ZnO/p-GaN heterojunction formed by RF magnetron sputtering method

Yanwei Shen,Xiang Chen,Xiaoqin Yan,Fang Yi,Zhiming Bai,Xin Zheng,Pei Lin,Yue Zhang 한국물리학회 2014 Current Applied Physics Vol.14 No.3

High quality n-ZnO/p-GaN heterojunction was fabricated by growing highly crystalline ZnO epitaxial films on commercial p-type GaN substrates via radio frequency (RF) magnetron sputtering. Low-voltage blue light emitting diode with a turn-on voltage of w2.5 V from the n-ZnO/p-GaN heterojunction was demonstrated. The diode gives a bright blue light emission located at w460 nm and a low threshold voltage of 2.7 V for emission. Based on the results of the photoluminescence (PL) and electroluminescence (EL) spectra, the origins of the EL emissions were studied in the light of energy band diagrams of ZnOeGaN heterojunction, and may attribute to the radiative recombination of the holes in p-GaN and the electrons injected from n-ZnO, which almost happened on the side of p-GaN layer. These results may have important implications for developing short wavelength optoelectronic devices.