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Jan Jozefczuk,Ewa Konopka,Joanna Beata Bier1a,Ilona Trojanowska,Agnieszka Sowin´ska,Rafa1 Czarnecki,Lucjan Sobol,Pawe1 Jo´zefczuk,Weronika Surd,Bo_zena Cukrowska 한국식품영양과학회 2018 Journal of medicinal food Vol.21 No.2
There is evidence that children with autism spectrum disorders (ASDs) display an increased immune reactivity against gluten, which is supposed to be the effect of intestinal barrier abnormalities. The aim of study was to evaluate the relation of antibody induced by gluten to zonulin and intestinal fatty acid binding proteins (I-FABP), that is, serological markers of an impaired gut barrier. The study included 77 patients with ASDs. Zonulin, I-FABP, celiac-specific antibodies, anti-gliadin antibodies (AGA), and antibodies against neural transglutaminase 6 (TG6) of immunoglobulin (Ig) A and IgG classes were detected in sera. Celiac-specific antibodies were negative in all ASD children, four children (5.2%) had positive anti-TG6 antibodies, and increased AGA-IgG production was found in 21 patients (27.3%). Mean levels of zonulin and I-FABP in ASD patients were similar to those found in healthy controls and revealed a negative correlation with age, whereas regression analysis revealed a significant positive relationship between antibody production and the age. Serum concentrations of zonulin and I-FABP showed no statistically significant association with antibody positivity. An increased production of antibodies related to gliadin and neural TG6 in ASD children is not related to serological markers of an impaired intestinal barrier.
Karol Fija kowski,Pawe Nawrotek,Magdalena Struk,Marian Kordas,Rafa Rakoczy 한국자기학회 2013 Journal of Magnetics Vol.18 No.3
This work presents results of the study which concerns the influence of the rotating magnetic field (RMF) on the growth rate, cell metabolic activity and ability to form biofilms by E. coli and S. aureus. Liquid cultures of the bacteria were exposed to the RMF (RMF frequency f = 1-50 Hz, RMF magnetic induction B = 22-34 mT, time of exposure t = 60 min, temperature of incubation 37℃). The present study indicate the exposition to the RMF, as compared to the unexposed controls causing an increase in the growth dynamics, cell metabolic activities and percentage of biofilm-forming bacteria, in both S. aureus and E. coli cultures. It was also found that the stimulating effects of the RMF exposition enhanced with its increasing frequencies and magnetic inductions.
The management of post-transplantation recurrence of hepatocellular carcinoma
Luckshi Rajendran,Tommy Ivanics,Marco PAW Claasen,Hala Muaddi,Gonzalo Sapisochin 대한간학회 2022 Clinical and Molecular Hepatology(대한간학회지) Vol.28 No.1
The annual incidence of hepatocellular carcinoma (HCC) continues to rise. Over the last two decades, liver transplantation (LT) has become the preferable treatment of HCC, when feasible and strict selection criteria are met. With the rise in HCC-related LT, compounded by downstaging techniques and expansion of transplant selection criteria, a parallel increase in number of post-transplantation HCC recurrence is expected. Additionally, in the context of an immunosuppressed transplant host, recurrences may behave aggressively and more challenging to manage, resulting in poor prognosis. Despite this, no consensus or best practice guidelines for post-transplantation cancer surveillance and recurrence management for HCC currently exist. Studies with adequate population sizes and high-level evidence are lacking, and the role of systemic and locoregional therapies for graft and extrahepatic recurrences remains under debate. This review seeks to summarize the existing literature on post-transplant HCC surveillance and recurrence management. It highlights the value of early tumour detection, re-evaluating the immunosuppression regimen, and staging to differentiate disseminated recurrence from intrahepatic or extrahepatic oligo-recurrence. This ultimately guides decision-making and maximizes treatment effect. Treatment recommendations specific to recurrence type are provided based on currently available locoregional and systemic therapies.
디테트라하이드로퍼퓨릴프로판과 용매를 포함하는 이성분계의 상평형 연구
박종기 ( Jong Kee Park ),빈영욱 ( Young Wook Bin ),노경호 ( Kyoung Ho Paw ),박소진 ( So Jin Park ) 한국공업화학회 2011 공업화학 Vol.22 No.4
디테트라하이드로퍼퓨릴프로판(Ditetrahydrofurfurylpropane, DTHFP, (CH2CH2CH2OCH)2C(CH3)2)과 용매인 사이클로헥산 (Cyclohexane), 노말헵탄(n-Heptane), 테트라하이드로퓨란(Tetrahydrofuran), 그리고 물을 포함하는 각 이성분계의 기액 상평형을 측정하였다. 기액 상평형 측정은 DTHFP의 농도가 낮은 영역에 대하여 실시하였다. NRTL 모델을 이용하여 기액 상평형을 해석하였으며 측정된 실험자료를 이용하여 NRTL 모델의 이성분계 상호작용 매개변수를 회귀분석하였다. Vapor liquid equilibria were measured for the binary systems of ditetrahydrofurfurylpropane (DTHFP) and some solvents such as cyclohexane, n-heptane, tetrahydrofuran, and water. Binary vapor liquid equilibria were measured for the diluted concentration range of DTHFP. NRTL model was used to analyze the measured data. With the experimental data, binary interaction parameters of the NRTL model were regressed.
Refractive Index and Surface Relief Grating Formation in DNA Based Dye-Doped Films
Alexandrina Tane,Francois Kajzar,Roxana Zgarian,Ileana Rau,Dawid Grabarek,Pawe Karpinski,Andrzej Miniewicz 한국고분자학회 2013 Macromolecular Research Vol.21 No.3
The refractive index and surface relief grating formation in deoxyribonucleic (DNA) based thin films,functionalized with the well known fluorophore LDS698, was studied in holographic two beam coupling geometry and as function of the polarization of incident laser beams. The DNA biopolymer used was functionalized with cetyltrimethylammonium chloride (CTMA) surfactant. If both beams polarization are parallel (p-p) a refractive index grating is formed, as is usually observed, this is also the case when both beams polarizations are perpendicular (sp). This fact is tentatively interpreted as due to the DNA matrix chirality. Also formation of a surface relief refractive index grating is observed in these materials for the first time, in contrary to earlier observations reported in literature. This effect is tentatively explained as due to the creation of an electrostatic bond between DNA and the guest molecules,which are electrically charged.
( Radoslaw Sikora ),( Elzbieta Grzesiuk ),( Sikora Anna ),( Justyna Wojtowicz Sienko ),( Piotr Piela ),( Urszula Zielenkiewicz ),( Karolina Tomczyk Zak ),( Aleksandra Chojnacka ),( Pawe Kowalczyk ),( 한국미생물 · 생명공학회 2011 Journal of microbiology and biotechnology Vol.21 No.3
Ferric ion-respiring microorganisms (FRMs) are a group of prokaryotes that use Fe(III) as well as other metals as terminal electron acceptors in the process of anaerobic respiration. Special attention is paid to a biotechnological significance of FRMs because of their potential role in electricity production in microbial fuel cells (MFCs) where the terminal acceptor of the electrons during anaerobic respiration is not a ferric ion but the anode. One of the best known FRMs is the Shewanellaceae family. Most of the Shewanella species have been isolated from marine environments. In this report, sugar beet molasses and ferric oxide were successfully used in the selection of a bacterial consortium capable of dissimilatory Fe(III) reduction in a long-term continuous culture. The inoculum was a sample of eutrophic lake bottom sediment. Among the bacteria present in this culture were representatives of the Enterobacteriaceae, and the genera Pseudomonas, Arcobacter, and Shewanella. Two non-marine Fe(III)-reducing Shewanella-related clones named POL1 and POL2 were isolated. The abilities of the POL1 and POL2 isolates to metabolize a panel of 190 carbon sources were examined using a BIOLOG assay. The results confirmed the abilities of the shewanellas to utilize a broad range of carbon substrates. The utility of the POL1 and POL2 isolates in H-type MFCs operating on pyruvate or molasses was demonstrated. The operation of the MFC with shewanellas cultured on molasses was shown for the first time. A two-stage character of the fuel cell polarization curves, not previously noted in Shewanella MFC studies, was observed.
Nor Naimah Rosyadah Ahmad,Yang Lee,Mohamad Rezi Abdul Hamid,Tinia Idaty Mohd Ghazi,Rizwan Nasir,Choe Peng Leo,Siaw Paw Koh,Jagadeesh Pasupuleti,Sieh Kiong Tiong 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.128 No.-
Membrane-based separation is a promising technology for hydrogen separation and purification due toits low energy consumption. Conventional membranes, such as polymeric membranes, often suffer frompermeability-selectivity trade-offs weakening their potential for challenging gas separations. Metalorganicframeworks (MOFs) with uniform apertures, high porosities, large internal surface areas, and tunablefunctionalities make them excellent fillers in mixed matrix membranes (MMMs) fabrication forhydrogen separation. This review evaluates current state-of-the-art MMMs performances, explores thechallenges in MMMs fabrication, and discusses current strategies in MOF-based MMMs fabrication andmodification aspects to enhance the membrane performance, specifically for H2/CO2, H2/CH4, and H2/N2 separation. Moreover, the hydrogen separation performance of MOF-based MMMs at elevated temperaturesand pressure and improvement in antiaging and antiplasticization properties are discussed indetail. The outlook and perspectives for MOF-based MMMs for hydrogen separation are also provided. This review offers insight into the potential of MOFs as porous fillers in MMMs fabrication for hydrogenseparation application.