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      • KCI등재

        Influence of firing temperature on selected mechanical properties of alluvial clay blended with a limestone and kaolin mixture

        Mengue Paulette Cathy,Mbessa Michel,Cengiz Özgür,Kaze Rodrigue Cyriaque,Salman Alomayri Thamer,Pettang Chrispin 한국자원공학회 2023 Geosystem engineering Vol.26 No.4

        The present study investigated the feasibility of low-energy and low-cost production of ceramic products from widely available alluvial clay in Batchenga, Cameroon, using low firing temperatures. A mixture consisting of 70% kaolin and 30% limestone was prepared and used as an additive in fired alluvial clay bricks. A series of samples was prepared in which the additive made up 5, 10 or 15% of the clay products, and the samples were heated at 700, 750, 800, 850 or 900 °C. The raw materials and ceramic products were characterised using x-ray diffractometry, scanning electron microscopy, bulk density, porosity, thermogravimetry and differential scanning calorimetry analysis. The results revealed that products with 10% additive showed improved mechanical performance and densification after heating at all tested temperatures. A compressive strength of 28 MPa was recorded when the product was heated at 800 °C. A drastic decrease in performance was observed for all samples heated at above 800 °C; this was likely due to the conversion of CaCO3 into CaO, resulting in the appearance of voids within the matrix that weakened the structure. This is in line with the high-water absorption and porosity values recorded. The resultant ceramic products have potential for use in engineering applications.

      • The Movement Sciences and Dance Research : Past, Present, and Future

        Co^te'-Laurence, Paulette 한국체육무용국제교류학회 2001 한국체육무용국제교류학회지 Vol.7 No.-

        It is a great honor to be here today among such a prominent group of delegates. I thank the Organizing Committee for this exciting opportunity. The theme of the conference, which focuses on how we, as researchers and educators, may contribute to improve the quality of human life, covers a wide spectrum of disciplines. Dance science, one of these research areas, addresses an art that represents one of many categories of human physical activities. What differentiates dance from sport and other physical activities is its intent. Unlike sports where the primary intent is to perform to a level that enables victory over an opponent, the intent of dance is to communicate a message to an audience. How, therefore, may dance contribute to improve the quality of human life? Todays education policymakers increasingly promote a holistic approach to curriculum development, an approach that may help younger generations to cope with contemporary societys challenging lifestyle changes. The arts, more specifically dance, is amongst the few cultural activities which promote opportunities to enjoy beauty, express views, emotions, dreams, and ideas, and even challenge the status quo. As spectators, creators, or performers, experiencing the arts can enrich our lives in a number of ways. Engage in multisensory visualization for a moment to appreciate the joy of making beautiful music, watching a play, dancing, or admiring a favorite painters masterpiece in a spacious museum. The arts can complement an individuals intellectual, physical, and affective needs for a balanced life. What do we know about dance, about learning dance skills? What do we know about instructional methods and cognitive processes which lead to superior performance? Answers to these questions may be found in the movement sciences, In fact, many of the areas of specialization listed for this conference do include dance. There are research areas such as dance training, dance medicine, dance technology, dance psychology, and dance biomechanics. This paper will concentrate mainly on the contribution of the discipline of motor learning to dance science. A brief historical background will first be presented, followed by the present status of dance science, and future directions. However, I would like to conclude this introduction by offering a general definition of dance, based on Hannas (1999) theory. First, dance consists of expressive movements and specialized skills. Professional dancers, like top athletes, have developed their motor skills over years of rigorous training. They have developed superior motor control for highly complex and aesthetically pleasing movements. These dancers communicate the artists message to an audience. Second, dance is generally performed with others on a limited space. This implies that dancers must synchronize their movements and relate to each other. Third, dance movements are rhythmical and performed to music or some form of accompaniment. Some choreographies are performed to highly complex music, which increases the level of difficulty of dance skills. For example, the dance Gloria by Mark Morris, was intended to illustrate the great music of Vivaldi. Finally, dance is a culturally influenced activity which has symbolic potential. It has, and continues to play a crucial role in world communities, as a vehicle for communication and a reflection of social values.

      • KCI등재

        Comparison of Fixed versus Calculated Activity of Radioiodine for the Treatment of Graves Disease in Adults

        Abigail U. Canto,Paulette N. Dominguez,Cecilia A. Jimeno,Jerry M. Obaldo,Ruben V. Ogbac 대한내분비학회 2016 Endocrinology and metabolism Vol.31 No.1

        Background: Radioactive iodine as a treatment modality has been shown in several studies to be a safe and effective therapy for Graves disease. However, there is still no uniformity regarding optimal dosing method. The aim of this study is to compare the efficacy of calculated and fixed dosing of radioiodine for the treatment of Graves disease. Methods: A hundred twenty-two patients diagnosed with Graves disease were randomized to receive either fixed or calculated dose of radioiodine. Those randomized to fixed activity received either low fixed activity at 9.9 mCi for thyroid gland size <40 g or high fixed activity at 14.9 mCi for thyroid gland size 40 to 80 g, and those grouped to calculated activity received 160 µCi/g of thyroid tissue adjusted for 24 hours radioiodine uptake. Thyroid function tests (free thyroxine [T4] and thyroid stimulating hor mone [TSH]) were monitored at 10, 16, and 24 weeks after radioactive iodine therapy. The primary outcome, treatment failure was defined as persistently elevated free T4 and low TSH. Results: Of the 122 patients randomized, 56 in the fixed dose group and 56 in the calculated dose group completed the follow up. At the end of 6 months, the percentage of treatment failure was 37.50% in the calculated dose group versus 19.64% in the fixed dose group with a relative risk of 0.53 (95% confidence interval, 0.28 to 0.98) favoring the fixed dose group. Conclusion: Fixed dose radioiodine has a significantly lower incidence of persistent hyperthyroidism at 6 months post-radioac tive therapy.

      • KCI등재

        Design synthesis and optimization of a 4-SPS intrinsically compliant parallel wrist rehabilitation robotic orthosis

        Hussain Shahid,Jamwal Prashant K,Van Vliet Paulette 한국CDE학회 2021 Journal of computational design and engineering Vol.8 No.6

        Neuroplasticity allows the human nervous system to adapt and relearn motor control following stroke. Rehabilitation therapy, which enhances neuroplasticity, can be made more effective if assisted by robotic tools. In this paper, a novel 4-SPS parallel robot has been developed to provide recovery of wrist movements post-stroke. The novel mechanism presented here was inspired by the forearm anatomy and can provide the rotational degrees of freedom required for all wrist movements. The robot design has been discussed in detail along with the necessary constructional, kinematic, and static analyses. The spatial workspace of the robot is estimated considering various dimensional and application-specific constraints besides checking for singular configurations. The wrist robot has been further evaluated using important performance indices such as condition number, actuator forces, and stiffness. The pneumatic artificial muscles exhibit varying stiffness, and therefore, workspace points are reached with different overall stiffness of the robot. It is essential to assess robot workspace points that can be reached with positive forces in actuators while maintaining a positive definite overall stiffness matrix. After the above analysis, design optimization has been carried out using an evolutionary algorithm whereby three critical criteria are optimized simultaneously for optimal wrist robot design.

      • KCI등재

        Regulation of HBV-specific CD8+ T cell-mediated inflammation is diversified in different clinical presentations of HBV infection

        Colin M. Dinney,Lu-Dong Zhao,Charles D. Conrad,Jay M. Duker,Richard O. Karas,Zhibin Hu,Michele A. Hamilton,Thomas R. Gillis,Thomas M. Parker,Bing Fan,Andrew H. Advani,Fred B. Poordad,Paulette L. Fauce 한국미생물학회 2015 The journal of microbiology Vol.53 No.10

        Chronic HBV infection is the leading cause of liver cirrhosis and hepatic cancer, but the individual responses toward HBV infection are highly variable, ranging from asymptomatic to chronic active hepatitis B inflammation. In this study, we hypothesized that the different individual responses to HBV infection was associated with differences in HBV-specific CD8+ T cell-mediated inflammation and cytotoxicity. Blood samples were collected from subjects with asymptomatic HBV-infection, subjects undergoing active chronic HBV flares (active CHB), and subjects with HBV-infected hepatocellular carcinoma (HBV-HCC). By tetramer staining, we found that all three groups had similar frequencies of HBVspecific CD8+ T cells. However, after HBV peptide stimulation, the HBV-specific CD8+ T cells in asymptomatic subjects had significantly stronger interferon gamma (IFN-γ), tumor necrosis factor alpha (TNF-α), and CD107a expression than those in active CHB and HBV-HCC patients. Examination of surface marker expression revealed that the PD-1-Tim-3- double-negative cell population was the main contributor to HBV-specific inflammation. In active CHB patients and HBV-HCC patients, however, the frequencies of activated PD-1-Tim-3- cells were significantly reduced. Moreover, the serum HBV DNA titer was not correlated with the frequencies of HBV-specific CD8+ T cells but was inversely correlated with the frequencies of IFN-g-expressing and CD107a-express cells in response to HBV stimulation. Together, our data demonstrated that the status of HBVspecific CD8+ T cell exhaustion was associated with different clinical outcomes of chronic HBV infection.

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