300명 환자 수지 재접합수술의 임상적고찰

한현언 대한성형외과학회 1992 Archives of Plastic Surgery Vol.19 No.3

On May 23, 1962, Malt and McKahnn of Boston replantated the amputated right arm of a 12-year-old boy. Postoperatively the boy survived with his arm restored. Following this replantationin Boston, surgery in Korea has developed much since the first replantation of a severed left finger was successfully tried at the Kyung Hee University Medical Center in 1975. The replantation operation should not only succeed but also ensure a proper function of the replantated hand and digits. Between January 1989 and July 1991, the author has operated on 300 patients. The author's modified method of replantation procedures is as follows : The flexor tendon is repaired first and bone fixation work is done next; then the nerves were repaired before vessels were repaired. The result was that the digit was neurorraphically complete with its sensations and functions restored to it. The following results were obtained from the clinical analyses and follow-up of the patients : 1. The highest percentage of the patients belongs to the third decade with 133 cases(44.3%) and the male to female ration is 9 to 1. 2. Patients transferred from other hospitals amount to 129 cases (43%) 3. As for territorial distribution, Kyunggi Province topped with 192 cases (64%) 4. The most common level of amputation is in proximal phalanageal bone and proximal phalangeal joint with 242 digits (39.9%) 5. The success rate in all the operations is 97 percent.

Chitosan 첨가에 의한 육제품 개발에 관한 연구(Ⅰ) : The Effect on Sausage Batter Color 소시지 Batter의 발색에 미치는 영향

김언현 건국대학교 자연과학연구소 1999 建國自然科學硏究誌 Vol.10 No.1

This study aimed for the examination of color characteristics and safaty of sodium nitrite - free sausage products. Experiments were carried out on the frankfurter sausage batter which was stored at 5℃ for 3 days. Physicochemical characteristics of sausages batter treated processed with low density chitosan+G.D.L.(glucono-δ-lactone) solution were evaluated during the storage time. pH in sausage batters with chitosan were lowered than nitrite treated one. Gel strength in sausage batter with chitosan was significantly higher than nitrite gel. In sausage batter phase, chitosan enhanced stability of all sausage batter color compare with nitrite treated one except lightness.

인삼 조사포닌이 다이옥신-노출 기니픽의 혈액화학 지수에 미치는 효과

김언현 建國大學校 自然科學硏究所 2001 建國自然科學硏究誌 Vol.12 No.-

본 연구는 자성 기니픽에 있어 2,3,7,8-tetrachlo rodibenzo-p-dioxin (TCDD)-유도 독성에 대한 홍삼 조사포닌의 방어 효과를 구명하기 위하여 수행되었다. 총 80마리의 자성 기니픽 (800 ± 20g)을 8군으로 나누어 Gl (정상 대조군)에 대하여는 TCDD의 운반체와 생리식염수를, G2 (TCDD단독 투여군)에게는 TCDD (1 μg/kg b.w.)와 생리식염수를 복강 주사하였다. 한편, G3, G4 (조사 포닌 단독투여군), G5, G6군 (조사포닌 전 투여군)과 G7, G8 (조사포닌 후 투여군)에 대하여는 각각 홍삼 조사포닌[10 (G3, G5, G7), 20 mg/kg b.w. (G4, G6, G8)]을 TCDD 투여 7일전 혹은 TCDD 투여 7일 후부터 각각 5주 혹은 3주간 복강 주사하였으며, TCDD (1 μg/kg b.w.)는 1회 복강으로 주사하였다. G2군의 경우 체중은 TCDD-노출 후 3일째부터 유의하게 감소한 반면, 사포닌단독 투여군인 G2, G4군과 전 투여군인 G5, G6군에 있어서는 실험기간 동안 정상 대조군에 비하여는 체중 증가가 억제되나 G2군에 비하여는 유의하게 증가 (p<0.01) 하였으며, 홍삼 조사포닌 후 투여군인 G7, G8군에 있어서도 조사포닌 투여 전까지는 G5군과 유사한 경향을 나타냈으나 조사포닌 투여 후부터는 G2군에 비하여 체중 감소가 현저히 억제 되있다. G2군에서는 잘 알려진 바와 같이 간, 비장, 췌장, 신장 및 심장기능과 관련된 임상화학 지수가 유의하게 증가하거나 감소한 반면, 홍삼 조사포닌 처리군인 전투여군과 동시 투여군 모두에서는 유의하게 억제되는 것을 관찰할 수 있었다(p<0.05). 이상의 결과는 인삼의 주요 활성성분으로 알려진 조사포닌이 다이옥신에 의하여 유도되는 독성을 방어하며 이러한 방어 효과는 성별과 무관하게 발현되었다. This study was carried out to investigate the effect of crude ginseng saponin (CGS) on blood chemical parameters in adult female guinea pigs exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). A total of 80 guinea pigs (800 ± 20g) were divided into 8 groups; group 1 (normal control group) was given vehicle (corn oil containing small amount of acetone and MDSO) and saline; group 2 (single TCDD-treated) received TCDD (1 μg/kg, i.p.) and saline (i.p.); group 3 and 4 were administered CGS at a daily i.p. doses of 10 and 20 mg/kg for 4 weeks, respectively; groups 5 and 6 were administered CGS (10 and 20 mg/kg, respectively) for 5 weeks starting 1 week before TCDD-exposure; groups 7 and 8 were administered CGS (10 and 20 mg/kg, respectively) for 3 weeks from 1 week after TCDD-exposure. CGS was prepared by Diaion HP-20 adsorption chromatography. Body weights of G2 were significantly decreased from the 2nd week after TCDD-exposure (p<0.01). Body weights of the CGS-treated groups were also decreased by TCDD-exposure but the weight loss was greatly retarded compared with that of G2. Increase in blood glucose, amylase, lipase, total cholesterol, triglyceride, AST and LDL-cholesterol levels by TCDD exposure was significantly attenuated by the CGS-treatment (p<0.05). From these results, we found that saponin, the main active ingredient of ginseng, played a protective role in TCDD-induced toxicity and ginseng protected female animals from dioxin-induced toxic manifestation.

糖類의 添加가 肉의 細菌性腐敗에 미치는 影響

金彦玄 건국대학교 1979 論文集 Vol.9 No.1

This experiments were carried out to investigate the effect of sugars on psychrophillic's spoilage in ground meat. Change of pH value, utilization of sugars and determination of sugars in proper level to prolongation of shelf were studied during storage at 5℃. The results obtained were summarized as follow; 1.PH value in 2% glucose treated ground beef was 5.25 (pork, 5.1), in 5 % glucose treated ground beef was 5.15 (pork, 4.45) and in 10% glucose treated ground beef was 4.5 (pork, 4.1). 2.Growth of variouse micro-organisms in ground beef samples containing 2 % glucose after 9 days at 5℃ were as follow; ① Average total aerobes counts in control(beef) were 8.3×109 cells/g (pork,1.2×1010 cells/g) and in glucose treated were 6.0×107cells/g (pork, 7.8×105 cells/g) ② Average coliformbacteria control were 3.5×105 cells/g (fork, 3.6×105 cells/g) and in glucose treated were 2.4×103 cells/g (park 2.8×104 cells/g) ③ Average lactic acid producing bacteriacounts in control were 5.8×107cell/g (pork 5.5×107cells/g and in glucose treated were 5.7×106 cells/g (pork, 4.5×106 cells/g) ④ Average lactobacillus counts in control were 3.6×105 cells/g (pork, 3.3×105 cells/g) and in treated were 4.2×106 cells/g) but, there was no indication of bacterial interaction between Lactobacillus and pseudomonas species. 3.In glucose treated samples, all added glucose was depleted completely when 12 days (9 days in pork) was passed in 2% glucose containing ground beef, 16 days(same days in pork) in 5 % glucose containting one. And pH started to rise from this pont. 4.The addition of glucose to ground meat more prolonged its average shelf life at refrigerated temperature (5℃) than control one. 7 days(8 days in pork) in 2% glucose level, 9 days(10 days in pork) in 5 % glucose level and 12 days(same in pork) in 10 % glucose level were prolonged than control meats.

Epidemic Modelling for Identifing Risk factor Associated with Highly Pathogenic Avian Influenza subtype H5N8 Outbreaks on Broiler Duck Farms in South Korea

Woo-Hyun Kim(Woo-Hyun Kim),Jae-Uk An(Jae-Uk An),Junhyung Kim(Junhyung Kim),Oun-Kyong Moon(Oun-Kyong Moon),SunHak Bae(SunHak Bae),Seongbeom Cho(Seongbeom Cho) 한국예방수의학회 2018 한국예방수의학회 학술대회자료집 Vol.2018 No.-

코딩 교육을 위한 그래픽 기반의 게임 제작 도구 개발

박현식(Hyun Sik Park),박민우(Min Woo Park),나정일(Jeong Il Na),한경현(Kyung-Hyun Han),황성운(Seong Oun Hwang) 대한전자공학회 2019 대한전자공학회 학술대회 Vol.2019 No.11

Research on changes in social perceptions of games, software education, and coding education is being actively conducted. One of the most important things in the education of young students is how to draw their attentions. Games are powerful tools to draw their interests, and we suggest a simple and easy way to create a game.

Risk Factors Associated with Highly Pathogenic Avian Influenza (HPAI) subtype H5N8 Outbreaks on Broiler Duck Farms in South Korea

Woo-Hyun Kim(Woo-Hyun Kim),Jae-Uk An(Jae-Uk An),Junhyung Kim(Junhyung Kim),Oun-Kyong Moon(Oun-Kyong Moon),SunHak Bae(SunHak Bae),Seongbeom Cho(Seongbeom Cho) 한국예방수의학회 2017 한국예방수의학회 학술대회자료집 Vol.2017 No.-

승용차 외장측면거울 주위의 유동 특성

한용운(Yong Oun Han),김정현(Jung Hyun Kim),황인호(In Ho Hwang),서정복(Jung Bok Seo),임병훈(Byung Hoon Lim),정의헌(Ui Hyun Jung) 대한기계학회 2007 대한기계학회 춘추학술대회 Vol.2007 No.5

In order to investigate the vortex body frame interaction around the side mirror of a passenger car velocity vector fields in the wake, pressure distributions and boundary layer flows over both the mirror surface and the mirror housing, have been measured by several experimental tools. It was resulted that only within an half downstream distance of the mirror span there appears the recirculation zone, and also found that vortex trail towards to the driver side window between A and B pillars, making the acoustic noise and vibration. Wake vortex rolls up after this recirculating zone and makes the trail of the vortex center towards the driver side window, which was also confirmed by measurements of wake velocity vectors in the vertical sections of the trail and visualization over the side mirror surfaces as well. It was also observed that total pressure distribution over the mirror surface has the minimum peak near the lower tip region which can be considered as the origin of the vortex center. It can be concluded that the geometrical modification of the lower tip and the upper root area of the mirror housing is the key to control the wake vortex.

갈륨액체금속 이온원과 인듐액체금속 이온원의 빔 특성에 대한 연구

현정우,임연찬,정강원,정원희,박철우,이종향,강승언 한국공작기계학회 2005 한국공작기계학회 춘계학술대회논문집 Vol.2005 No.-

본 연구에서는 인듐 액체금속이온원을 제작하여 빔 특성에 대해 연구를 하였으며, 기존에 연구를 하였던 갈륨 액체금속이온원의 빔특성과 비교 분석 하였다. 빔특성 분석을 위해 빔 안정도, 전류-전압특성곡선, 에너지 퍼짐을 측정하였다. 액체금속이온원에 사용되는 액체금속 저장소 및 바늘전극(tip)은 500μm의 직경을 갖는 텅스텐을 사용하였으며, 국내에서 제작된 제품을 사용하였다. 액체금속 저장소의 구조는 이전에 구상하여 연구가 이루어진 6개의 pre-etching된 텅스텐와이어(wire)가 묶여진 형태를 사용하였다.

Expression of Epidermal c-Kit+ of Vitiligo Lesions Is Related to Responses to Excimer Laser

( Oun Jae Park ),( Ji Su Han ),( Sang Hyung Lee ),( Chan Sik Park ),( Chong Hyun Won ),( Mi Woo Lee ),( Jee Ho Choi ),( Sung Eun Chang ) 대한피부과학회 2016 Annals of Dermatology Vol.28 No.4

Background: The survival and growth of melanocytes are controlled by the binding of stem cell factor to its cell surface receptor c-kit+ (CD117). We have observed that c-kit+ melanocytes existed in some lesions of vitiligo, while Melan A+ cells were absent. Objective: To verify possible relation between c-kit+ expression and treatment response in non-segmental vitiligo lesions Methods: Skin biopsies were done from the center of the 47 lesions from the 47 patients with non-segmental vitiligo. Expression of c-kit+ and Melan A, and amounts of melanin in the epidermis were assessed in each lesion, and treatment responses to excimer laser were evaluated. Results: Thirty-five of the 47 lesions (74.5%) had c-kit+ phenotypes. There was significant difference of c-kit staining value between good responders in 3 months of excimer laser treatment (average of 24 sessions) and the others. Conclusion: c-Kit expression in vitiliginous epidermis may be related to better treatment responses to excimer laser. (Ann Dermatol 28(4) 457∼463, 2016)