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      • IgG3결핍 천식 환자에서 면역 글로불린 치료로 호전된 1례

        김희규,옥철호,정만홍 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.2

        반복적인 호흡기 감염으로 천식 악화가 재발되는 환자는 면역 결핍이 그 원인일 수 있다. 저자들은 20년 전부터 기관지 천식으로 진단받고 최근 들어 잦은 호흡기 감염과 천식 악화가 발생한 환자에서 IgG3결핍을 확인하여 면역 글로불린 투여 후 임상적으로 호전된 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Asthma is precipitated into acute episode of airway obstruction by respiratory infection. Also, some immunological abnormalities including deficiencies of IgG subclasses are reported in patients with asthma. A 65 year old woman, who has a 20 years history of bronchial asthma and allergic rhinitis, has been suffering from recurrent upper and lower respiratory infection for 2 years. She has been admitted frequently by asthma exacerbation. We evaluated her immunoglobulin level. IgG subclass III level was reduced at 14.3 mg/dl (normal range 23.0~196.0 mg/dl) with other IgG subclass profiles in the normal range. So, we administrated IVIG (intravenous immunoglobulin) monthly 0.4 g/kg dose for symptomatic IgG3 deficiency. She was much improved in clinical course : without asthma exacerbation, recurrent respiratory infection, and need for antibiotics. So, the symptomatic IgG subclass deficient patients may be candidates for IVIG replacement.

      • 민간부문 건설사업관리 활성화방안

        이정희,장홍진,구교진,김옥규,현창택,김양현 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1

        Since, korean government introduced Construction Management system by the law in 1997, only a few public construction projects have been adopted the system Nevertheless there are many laws which are related in public construction projects, Construction Management is positively carried out by non-government. About the activation plan of Construction Management questionnaire was inquired by experts in construction. The purpose of this study is to give a solution by finding out the problem of the laws, reconstructions remodelings.

      • 일부지역 중·고등학생들의 흡연실태 조사연구

        신옥순,남철현,김복용,최연희,박선희,박경옥,구재희 慶山大學校 保健福祉硏究所 2002 保健福祉硏究 Vol.7 No.-

        This study was conducted to examine aspects of middle and high school students' drinking and smoking with analysis of related factors. The subjects of this study was 540 students in Kyungbuk Province. Data were collected from July, 2002 to September, 2002. The results of this study can be summarized as follows. 1. 43.6% of the boy students experienced smoking, while 12.2% of the girl students experienced it. 5.3% of the students at academy schools experienced smoking, while 44.7% of the students at vocational schools experienced it. 11.4% of the middle school students experienced smoking, while 33.9% of the high school students experienced it. 15.5% of them who lived in towns or villages experienced smoking and 38.3% of them who lived in small or medium sized cities experienced it.37.5% of the students who belonged to the lower economic class experienced smoking and 20.7% of the students who belonged to the upper economic class experienced it. 24.0% of the students who belonged to the middle economic class experienced it. It appears that the respondents showed significantly different smoking experience rates by gender, school types, grades, the number of family members, residences, and economic classes. 2. 14.5% of the respondents who lived with grandparents and parents experienced smoking and 26.5% of them who lived with parents experienced it. The smoking rate was significantly high in the groups of having one-parent, being unsatisfied with family life, making poor grades in studies, and having the father or the mother working as a salesperson. 3. 45.3% of the respondents who were unsatisfied with family life experienced smoking. The smoking rate of the respondents who were unsatisfied with it was significantly higher than that of the other groups. On the other hand, the smoking rates were not significantly different by daily life, schoolmate relation, health condition, and feeling stress. 4. According to smoking rate by frequency of drinking, 16.4% of the respondents who drank less than once a month smoked and 54.8% of them who drank more than twice a month smoked. The more frequently they drank, the higher their smoking rate was. Those who did exercise displayed significantly higher smoking rate than those who did not do exercise. Among the rates of the respondents' agonies, family disharmony was 50.5% and love problem was 39.2%. Economic condition preblem was 34.6%. It appeared that smoking was most influenced by the family disharmony. 5. The factors significantly influencing smoking experience were gender, school grade, schoolmate relation, score in studies, and exercise. From above results, it can be concluded that the students' smoking is a serious problems which can be resolved by simple approaches because it is interrelated complicatedly with gender, grade, family, school, etc. Schools, related organizations, and the government must closely work together to maximize the effectiveness of policy implementation concerning the smoking and drinking problem of the middle and high school students.

      • SCOPUSKCI등재

        뇌졸중환자의 사회적 재적응과 관련요인

        조남옥,서문자,김금순,김인자,최희정,정성희 성인간호학회 2001 성인간호학회지 Vol.13 No.1

        Social readjustment is very important in rehabilitation of stroke survivors. The purpose of this study was to examine the level of social readjustment and related factors in stroke survivors. Especially, to find the most useful predictor for social readjustment is a major point of this research. The study included 254 outpatients who were given follow-up care after discharge from. Occupational rehabilitation and resumption of the perceived meaningful social activity prios to the stroke were used to measure social readjustment. The resumptions of first meaningful social activity was the best predictor for life satisfaction in stroke survivors(r=.245, p<.01). The substance of perceived meaningful social activities were job, meeting with friends, hobby and activities for the family. The sum of meaningful social activities (r = 175. p<.01) and occupational rehabilitation (r= 116, p<.05) were significantly related to life satisfaction. There were significant difference in IADL, depression and life satisfaction according to resumption of meaningful social activity. But, occupational rehabilitation was not related to depression. The level of social readjustment was different between occupational rehabilitation and resumption of meaningful social activity. It was 45.7% in the first meaningful social activity and 36.6% in occupational rehabilitation. The related factors with resumption of the first meaningful social activity were that of IADL, depression, illness intrusiveness and cognitive function. And the level of IADL, illness intrusiveness, cognitive function, and age were significantly related to occupational rehabilitation. In conclusion, we suggest that the resumption of the first meaningful activity in stroke survivors is the best predictor of social rehabilitation. Thus. nurses need to work for resumption of meaningful activity as well as occupational rehabilitation.

      • Baroque藝術의 文獻的 考察 : Baroque란 단어를 중심으로 Centering on the World "Baroque"

        林玉姬 群山大學校 1984 論文集 Vol.9 No.-

        The history of Music is a flow without cease, whose art is transmitted by apprenticeship from father to son, from teacher to pupil. Men of music, who are men of religious, earthly, and social classes, change their desire with slow tempo. It is obvious that the taste of the musician of a (and all) generation should be changed, but often make a steady progress without a serious gap. No composer has been aware that he himself has arrived at the end of a period because basing on tradition, all of the creative musicians make a steady progress according to the changing taste. The late works of J.S.Bach publicly admited the past and simultaneously opened the door between classicism and Romanticism. In the "Logical draft for church music," Bach wrote that "since our artistic technique has been advanced and our taste has been very changed, it thus seems that the mode of premusic does not entertain us now." And he did not refer to the basic turnabout of history or to the generation gap and the opening of a new generation. But reconsidering the history of music from a distance, a contrast comes into existence. Blasting on this contrast, we can understand the guality of each other and decide the boundary between the adjacent periods from a distance. Of course, to demarcate the border line between them is not easy, but choosing the Baroque period from the late sixteenth century to the mid-eighteenth century, this thesis aims at discussing the Baroque Music through arts including architecture, painting and literature.

      • KCI등재

        피질하 혈관성 치매와 호모시스테인 및 MTHFR C677T 유전자 다형성의 상관관계

        김희진,김지영,김숙희,김원기,김용성,최병옥 대한치매학회 2004 Dementia and Neurocognitive Disorders Vol.3 No.2

        Background: Subcortical ischemic vascular dementia (SIVD) frequently causes dementia in elderly people, and elevated plasma homocysteine concentrations have been reported to be associated with vascular dementia. Although the homozygous C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene can induce hyperhomocysteinemia, the association between MTHFR C677T polymorphism and SIVD has not been studied. Therefore, we examined the association of SIVD with plasma homocysteine concentration and MTHFR C677T polymorphism. Methods: We enrolled 58 patients with vascular dementia (VaD), 43 patients with SIVD, 69 lacunar infarct patients without vascualr dementia (LOD), and 232 healthy individuals and checked their fasting plasma homocysteine levels and analyzed the C677T polymorphism in the MTHFR gene. Results: The mean plasma homocysteine level in VaD, SIVD, and LOD patients were significantly higher than that in healthy controls (p;0.01). The odds ratio adjusted with age, sex, hypertension, diabetes mellitus, and smoling were significantly higher in VaD (OR, 2.74; 95% CI, 1.04 to 7.23) and SIVD (OR, 3.12; 95% CI, 1.09 to 8.96) than that in controls. Compared with LOD, it was significantly higher in SIVD, but not in VaD (OR, 4.50; 95% CI, 1.05 to 19.26). In SIVD patients, the OR of plasma homocysteine level was higher in the TT genotype than those in the CC genotype (OR, 1.59; 95% CI, 1.01 to 2.49). Conclusions: Our findings suggest that elevated plasma homocysteine concentration and the MTHFR 6777 genotype are associated with SIVD.

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