Effects of Varying Levels of Whole Cottonseed on Blood, Milk and Rumen Parameters of Dairy Cows

Oguz, F. Karakas,Oguz, M.N.,Buyukoglu, T.,Sahinduran, S. Asian Australasian Association of Animal Productio 2006 Animal Bioscience Vol.19 No.6

Four lactating Holstein cows were used in a $4{\times}4$ Latin-square design to determine the effects of various levels of whole cottonseed (WCS) in diets on parameters including milk (yield and fat content), rumen fluid (pH, ammonia and TVFA) and blood (${\beta}$-carotene, vit. A, vit. E, urea, $NH_3$, Ca, P and Mg levels). Cows consumed 0, 1, 2 or 3 kg WCS per day. No significant differences were observed among the groups on analysed parameters except plasma vitamin E concentration. In addition, when the amount of cottonseed was increased, milk yield and milk fat content also tended to increase but this increase was not statistically significant. In conclusion, feeding of WCS up to 3 kg per day with ad libitum maize silage did not cause negative effects on milk yield, milk fat and blood vitamin levels in the short term in dairy cows.

A study on the topographical and geotechnical effects in 2-D soil-structure interaction analysis under ground motion

Oguz Akin Düzgün,Ahmet Budak 국제구조공학회 2011 Structural Engineering and Mechanics, An Int'l Jou Vol.40 No.6

This paper evaluates the effects of topographical and geotechnical irregularities on the dynamic response of the 2-D soil-structure systems under ground motion by coupling finite and infinite elements. A numerical procedure is employed, and a parametric study is carried out for single-faced slope topographies. It is concluded that topographic conditions may have important effects on the ground motion along the slope. The geotechnical properties of the soil will also have significantly amplified effects on the whole system motion, which cannot be neglected for design purposes. So, dynamic response of a soil-structure systems are primarily affected by surface shapes and geotechnical properties of the soil. Location of the structure is another parameter affecting the whole system response.

A novel design procedure for tractor clutch fingers by using optimization and response surface methods

Oguz Dogan,Fatih Karpat,Celalettin Yuce,Necmettin Kaya,Nurettin Yavuz,Hasan Sen 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.6

This paper presents a methodology for re-designing a failed tractor transmission component subjected to cyclic loading. Unlike other vehicles, tractors cope with tough working conditions. Thus, it is necessary to re-design components by using modern optimization techniques. To extend their service life, we present a design methodology for a failed tractor clutch power take-off finger. The finger was completely re-designed using topology and shape optimization approach. Stress-life based fatigue analyses were performed. Shape optimization and response surface methodology were conducted to obtain optimum dimensions of the finger. Two design parameters were selected for the design of experiment method and 15 cases were analyzed. By using design of the experiment method, three responses were obtained: Maximum stresses, mass, and displacement depending on the selected the design parameters. After solving the optimization problem, we achieved a maximum stress and mass reduction of 14% and 6%, respectively. The stiffness was improved up to 31.6% compared to the initial design.

Effects of Lycopene Alone or Combined with Melatonin on Methotrexate-Induced Nephrotoxicity in Rats

Oguz, Elif,Kocarslan, Sezen,Tabur, Suzan,Sezen, Hatice,Yilmaz, Zehra,Aksoy, Nurten Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.14

Methotrexate (Mtx), used for its anticancer and immunsuppresive properties, is known to be a nephrotoxic agent. We aimed to investigate the effects of lycopene (Lyc) alone or combined with melatonin (Mel) on Mtxinduced nephrotoxicity since both of these agents have antioxidant and anti-inflammatory effects. Nephrotoxicity was induced by intraperitoneal administration of methotrexate at a dose of 20 mg/kg. Treatment both with Lyc alone and Lyc combined with Mel provided significant reduction in tumor necrosis factor-alpha, interleukin 1-beta and ceruloplasmin levels in Mtx administered rats. Hovewer, Lyc combined with Mel provided a significant reduction also in NO levels. Hstopathological examination showed that there was an obvious improvement in the degenerative changes compared to Mtx administrated group with the Lyc combined Mel group giving best protection. In conclusion Lyc alone and combined with Mel provided significant improvement against renal damage caused by Mtx, preseumably via antioxidant and anti-inflammatory activities.

Effects of Surface Shapes and Geotechnical Conditions on the Ground Motion

Oguz Akin Düzgün,Ahmet Budak 대한토목학회 2015 KSCE JOURNAL OF CIVIL ENGINEERING Vol.19 No.5

The influences of surface geometry and local soil properties on ground motion are parametrically studied. The system response is numerically evaluated. In the modelling, finite and infinite elements are applied. Three types of topography (single-faced slopes, canyons and ridges) are taken into account. According to the results, topographic conditions, depth of the rigid bedrock and geotechnical properties have significance in the alteration of ground motion at the irregular soil surface and its surroundings. For all selected surface shapes, the most critical cases occur at top corners especially when the slope gets steeper. These cases are independent on the natural period of structures. The results correspond with those earthquakes where topographical effects are observed and could be seemed to be worthwhile from the perspective of earthquake engineering and seismology.

Impact of multiple firings and resin cement type on shear bond strength between zirconia and resin cements

Oguz, Ece Irem,Ozgur, Merve Erdog,Sungur, Sercan,Uctasli, Sadullah The Korean Academy of Prosthodonitics 2020 The Journal of Advanced Prosthodontics Vol.12 No.4

PURPOSE. The aim of this study was to evaluate the effect of multiple firings on the bond strength between yttriatetragonal zirconia polycrystals (Y-TZP) and 2 types of resin cements. MATERIALS AND METHODS. Sixty 3Y-TZP specimens (LAVA Frame Multi) were divided into 3 groups depending on the following firing procedures: (1) 2-firing cycles, (2) 5-firing cycles, (3) 10-firing cycles. Two samples from each group were investigated by using SEM to determine the morphological changes. All specimens were treated with 125 ㎛ airborne-particle abrasion and the surface roughness of each specimen was measured. The specimens from each firing group were then further divided into 2 subgroups (n = 9) to apply 2 types of resin cement (MDP-free resin cement: RelyX Unicem-RU, and MDP containing resin cement: Panavia F 2.0-PA). The shear bond strength (SBS) test was performed and failure types of all the debonded specimens were classified by using a stereomicroscope as adhesive, cohesive, and mixed. The statistical analysis of surface roughness and SBS data were performed by using 1-way ANOVA and 2-way ANOVA followed by Tukey-HSD tests (α=.05). Failure modes were calculated as a percentage for each group. RESULTS. The bond strength of RU and PA to the specimens obtained with 2 firings were not statistically different from each other (P=.1). However, the SBS values of PA were found to be significantly higher than RU for the specimens obtained with 5 and 10 firing cycles (P=.001 and P=.02, respectively). Surface roughness analysis revealed no statistical difference between groups (P=.2). The SEM analysis of samples fired 5- and 10- times showed irregularities and boundary loss in zirconia grains, and empty spaces between zirconia grains. CONCLUSION. The bond strength of PA cement was higher than that of RU to the zirconia subjected to repeated firings (5 and 10 firing cycles). When zirconia is subjected to multiple firings, using MDP-containing resin cement can be recommended.

Predicting the stiffness of shear diaphragm panels composed of bridge metal deck forms

Oguz O. Egilmez 국제구조공학회 2017 Steel and Composite Structures, An International J Vol.24 No.2

The behavior of building industry metal sheeting under shear forces has been extensively studied and equations have been developed to predict its shear stiffness. Building design engineers can make use of these equations to design a metal deck form bracing system. Bridge metal deck forms differ from building industry forms by both shape and connection detail. These two factors have implications for using these equations to predict the shear stiffness of deck form systems used in the bridge industry. The conventional eccentric connection of bridge metal deck forms reduces their shear stiffness dramatically. However, recent studies have shown that a simple modification to the connection detail can significantly increase the shear stiffness of bridge metal deck form panels. To the best of the author's knowledge currently there is not a design aid that can be used by bridge engineers to estimate the stiffness of bridge metal deck forms. Therefore, bridge engineers rely on previous test results to predict the stiffness of bridge metal deck forms in bracing applications. In an effort to provide a design aid for bridge design engineers to rely on bridge metal deck forms as a bracing source during construction, cantilever shear frame test results of bridge metal deck forms with and without edge stiffened panels have been compared with the SDI Diaphragm Design Manual and ECCS Diaphragm Stressed Skin Design Manual stiffness expressions used for building industry deck forms. The bridge metal deck form systems utilized in the tests consisted of sheets with thicknesses of 0.75 mm to 1.90 mm, heights of 50 mm to 75 mm and lengths of up to 2.7 m; which are representative of bridge metal deck forms frequently employed in steel bridge constructions. The results indicate that expressions provided in these manuals to predict the shear stiffness of building metal deck form panels can be used to estimate the shear stiffness of bridge metal deck form bracing systems with certain limitations. The SDI Diaphragm Design Manual expressions result in reasonable estimates for sheet thicknesses of 0.75 mm, 0.91 mm, and 1.21 mm and underestimate the shear stiffness of 1.52 and 1.90 mm thick bridge metal deck forms. Whereas, the ECCS Diaphragm Stressed Skin Design Manual expressions significantly underestimate the shear stiffness of bridge metal deck form systems for above mentioned deck thicknesses.

Season of Diagnosis and Survival of Advanced Lung Cancer Cases - Any Correlation?

Oguz, Arzu,Unal, Dilek,Kurtul, Neslihan,Aykas, Fatma,Mutlu, Hasan,Karagoz, Hatice,Cetinkaya, Ali Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.7

Introduction: The influence of season at diagnosis on cancer survival has been an intriguing issue for many years. Most studies have shown a possible correlation in between the seasonality and some cancer type survival. With short expected survival, lung cancer is an arena that still is in need of new prognostic factors and models. We aimed to investigate the effect of season of diagnosis on 3 months, 1 and 2 years survival rates and overall survival of non small cell lung cancer patients. Materials and Methods: The files of non small cell lung cancer patients that were stages IIIB and IV at diagnosis were reviewed retrospectively. According to diagnosis date, the patients were grouped into 4 season groups, autumn, winter, spring and summer. Results: A total of 279 advanced non small cell lung cancer patients' files were reviewed. Median overall survival was 15 months in the entire population. Overall 3 months, 1 and 2 years survival rates were 91.0%, 58.2% and 31.2% respectively. The season of diagnosis was significantly correlated with 3 months survival rates, being diagnosed in spring being associated with better survival. Also the season was significantly correlated with T stage of the disease. For 1 and 2 years survival rates and overall survival, the season of diagnosis was not significantly correlated. There was no correlation detected between season and overall survivals according to histological subtypes of non small cell lung cancer. Conclusion: As a new finding in advanced non small cell lung cancer patients, it can be concluded that being diagnosed in spring can be a favorable prognostic factor for short term survival.

Electroanalytical Determination of Copper(II) Ions Using a Polymer Membrane Sensor

Oguz Ozbek,Meliha Burcu Gurdere,Caglar Berkel,Omer Isildak The Korean Electrochemical Society 2023 Journal of electrochemical science and technology Vol.14 No.1

In this study, a new potentiometric sensor selective to copper(II) ions was developed and characterized. The developed sensor has a polymeric membrane and contains 4.0% electroactive material (ionophore), 33.0% poly(vinyl chloride) (PVC), 63.0% bis(2-ethylhexyl)sebacate (BEHS) and 1.0% potassium tetrakis(p-chlorophenyl)borate (KTpClPB). This novel copper(II)-selective sensor exhibits a Nernstian response over a wide concentration range from 1.0×10^-6 to 1.0×10^-1 mol L^-1 with a slope of 29.6 (±1.2) mV decade^-1, and a lower detection limit of 8.75×10-7 mol L^-1. The sensor, which was produced economically by synthesizing the ionophore in the laboratory, has a good selectivity and repeatability, fast response time and stable potentiometric behaviour. The potential response of the sensor remains unaffected of pH in the range of 5.0-10.0. Based on the analytical applications of the sensor, we showed that it can be used as an indicator electrode in the quantification of Cu²⁺ ions by potentiometric titration against EDTA, and can also be successfully utilized for the determination of copper(II) ions in different real samples.

Lack of any Association between Blood Groups and Lung Cancer, Independent of Histology

Oguz, Arzu,Unal, Dilek,Tasdemir, Arzu,Karahan, Samet,Aykas, Fatma,Mutlu, Hasan,Cihan, Yasemin Benderli,Kanbay, Mehmet Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1

Introduction: Lung cancer, the leading cause of cancer deaths, is divided into 2 main classes based on its biology, therapy and prognosis: non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Many cases are at an advanced stage at diagnosis, which is a major obstacle to improving outcomes. It is important to define the high risk group patients for early diagnosis and chance of cure. Blood group antigens are chemical components on erythrocyte membranes but they are also expressed on a variety of epithelial cells. Links between ABO blood groups with benign or malignant diseases, such as gastric and pancreas cancers, have been observed for a long time. In this study, we aimed to investigate any possible relationship between lung cancer histological subtypes and ABO-Rh blood groups. Materials and Methods: The files of 307 pathologically confirmed lung cancer patients were reviewed retrospectively. Cases with a serologically determined blood group and Rh factor were included and those with a history of another primary cancer were excluded, leaving a total of 221. The distribution of blood groups of the lung cancer patients were compared with the distribution of blood groups of healthy donors admitted to the Turkish Red Crescent Blood Service in our city in the year 2012. Results: There was no significant difference between patients with lung cancer of either type and the control group in terms of distribution of ABO blood groups and Rh factor (p: 0.073). There was also no relationship with non small cell cancer histological subtypes. Conclusions: In this study, we found no relationship between the ABO-Rhesus blood groups and NSCLC and SCLC groups. To our knowledge this is the first analysis of ABO blood groups in SCLC patients.