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      • SCIESCOPUSKCI등재

        Diversity and Ecology of Myxomycetes from Kütahya and Konya (Turkey) with Four New Records

        Ocak, Ijlal,Konuk, Muhsin The Korean Society of Mycology 2018 Mycobiology Vol.46 No.3

        In this study, we examined myxomycetes that developed in moist chamber cultures of substrata material collected from $K{\ddot{u}}tahya$ and Konya provinces in Turkey. We collected bark samples from living trees, plant litter from the ground, standing dead wood or stumps, and downed and decayed wood or bark and placed them in the moist chamber cultures. We identified 36 species belonging to 12 genera of myxomycetes. The species determined are listed, and four new records, Didymium balearicum Ing, Macbrideola oblonga Pando & Lado, Paradiacheopsis erythropodia (Ing) Nann-Bremek. and Perichaena pedata (Lister & G. Lister) G. Lister, are added to the mycoflora of Turkey.

      • SCIESCOPUSKCI등재

        The Effects of Restricted Feeding and Feed Form on Growth, Carcass Characteristics and Days to First Egg of Japanese Quail (Coturnix coturnix japonica)

        Ocak, N.,Erener, G. Asian Australasian Association of Animal Productio 2005 Animal Bioscience Vol.18 No.10

        A study was conducted to determine the effects of restricted feeding and feed form on the growth performance, characteristics of carcass and digestive tract, and days to first egg of Japanese quail (JQ, Coturnix coturnix japonica). A total of 240 oneweek-old JQ chicks were allocated randomly into 4 experimental groups that consisted of 3 replicates according to a 2${\times}$2 factorial arrangement for two feeding methods (ad libitum, AF and restricted feeding, RF) and two diet forms (mash, MD and crumble, CD). The JQ chicks were placed in a room with floor battery brooders and fed a commercial starter diet from 7 to 14 d of age. According to the experimental design, four treatments (1: ad libitum MD, 2: restricted MD, 3: ad libitum CD, and 4: restricted CD) were applied. Feed restriction was applied by 30% reduction of ad libitum feed intake for both MD and CD from 15 to 28 d of age. All birds were fed ad libitum with treatment diets from 29 d of age until the first laid egg seen (45 d of age). The commercial starter diet, MD and CD were in the same nutrient content (240 g crude protein with 13.4 MJ ME per kg diet). The body weight and overall feed conversion ratio (g feed/g gain) were higher (p<0.05) for the AF quails than the RF at 42 d of age. Carcass weights, dressing percentage and percentage yields of breast and back were similar for AF and RF groups at 42 d of age. The RF delayed (p<0.05) onset of egg production 2 days compared to the AF. Quail fed with the CD showed higher value (p<0.05) for carcass weight and dressing percentage at 42 d of age compared to birds fed with the MD. The interaction effect of feeding method${\times}$feed form on any of the studied parameters was not significant. The results suggest that feed restriction as in the present study can achieve a better feed conversion without reduction in carcass weight, and a significant benefit of feeding the crumble diet over the mash diet was obtained in terms of carcass weight in the JQ.

      • KCI등재
      • KCI등재

        Diversity and Ecology of Myxomycetes from Kutahya and Konya (Turkey) with Four New Records

        ( Ijlal Ocak ),( Muhsin Konuk ) 한국균학회 2018 Mycobiology Vol.46 No.3

        In this study, we examined myxomycetes that developed in moist chamber cultures of substrata material collected from K€utahya and Konya provinces in Turkey. We collected bark samples from living trees, plant litter from the ground, standing dead wood or stumps, and downed and decayed wood or bark and placed them in the moist chamber cultures. We identified 36 species belonging to 12 genera of myxomycetes. The species determined are listed, and four new records, Didymium balearicum Ing, Macbrideola oblonga Pando & Lado, Paradiacheopsis erythropodia (Ing) Nann-Bremek. and Perichaena pedata (Lister & G. Lister) G. Lister, are added to the mycoflora of Turkey.

      • XELOX Plus Bevacizumab vs. FOLFIRI Plus Bevacizumab Treatment for First-line Chemotherapy in Metastatic Colon Cancer: a Retrospective Study of the Anatolian Society of Medical Oncology

        Duran, Ayse Ocak,Karaca, Halit,Besiroglu, Mehmet,Bayoglu, Ibrahim Vedat,Menekse, Serkan,Yapici, Heves Surmeli,Yazilitas, Dogan,Bahceci, Aykut,Uysal, Mukremin,Sevinc, Alper,Hacibekiroglu, Ilhan,Aksoy, Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23

        Background: XELOX plus bevacizumab (XELOX-Bev) and FOLFIRI plus Bevacizumab (FOLFIRI - Bev) treatments are an effective strategies patients with metastatic colorectal cancer (mCRC).The aim of this study was to compare efficacy of first-line XELOX-Bev treatment vs FOLFIRI-Bev treatment for mCRC. Materials and Methods: A total of 409 patients with mCRC who received chemotherapy were included and divided into 2 groups. Group 1 (n=298) received XELOX-Bev and Group 2 (n=111) FOLFIRI-Bev. Comparisons were made in terms of overall (OS) and progression-free (PFS) survival, response rate (RR), and grade 3-4 toxicity. Results: Median follow-up was 11 months in Group 1 and 15 months for Group 2. Complete remission was observed in 29 (9.7%) and 2 (1.8%) patients, partial remission in 139 (46.6%) and 27 (24.5%), stable disease in 88 (29.5%) and 49 (44.1%) and progressive disease in 42 (14.1%) and 33 (30.0%) patients in Group 1 and 2, respectively. Median OS was 25 months (range 2-57 months, 95%CI; 22.2-27.7) for Group 1 and 20 months (range 1-67 months, 95%CI; 16.8-23.1) for Group 2 (p=0.036). Median PFS was 9.6 months (range 2-36 months, 95%CI; 8.8-10.4) for Group 1 and 9 months (range 1-44 months, 95%CI; 7.4-10.5) for Group 2 (p=0.019). Objective RR was 56.4% in Group 1 and 26.1% in Group 2 (p<0.001). Conclusions: First-line XELOX-Bev is more effective with a better response rate, prolongation of median PFS/OS, and a superior safety profile compared with FOLFIRI-Bev.

      • Albumin-globulin Ratio for Prediction of Long-term Mortality in Lung Adenocarcinoma Patients

        Duran, Ayse Ocak,Inanc, Mevlude,Karaca, Halit,Dogan, Imran,Berk, Veli,Bozkurt, Oktay,Ozaslan, Ersin,Ucar, Mahmut,Eroglu, Celalettin,Ozkan, Metin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15

        Background: Prior studies showed a relationship between serum albumin and the albumin to globulin ratio with different types of cancer. We aimed to evaluate the predictive value of the albumin-globulin ratio (AGR) for survival of patients with lung adenocarcinoma. Materials and Methods: This retrospective study included 240 lung adenocarcinoma patients. Biochemical parameters before chemotherapy were collected and survival status was obtained from the hospital registry. The AGR was calculated using the equation AGR=albumin/(total protein-albumin) and ranked from lowest to highest, the total number of patients being divided into three equal tertiles according to the AGR values. Furthermore, AGR was divided into two groups (low and high tertiles) for ROC curve analysis. Cox model analysis was used to evaluate the prognostic value of AGR and AGR tertiles. Results: The mean survival time for each tertile was: for the $1^{st}$ 9.8 months (95%CI:7.765-11.848), $2^{nd}$ 15.4 months (95%CI:12.685-18.186), and $3^{rd}$ 19.9 months (95%CI:16.495-23.455) (p<0.001). Kaplan-Meier curves showed significantly higher survival rates with the third and high tertiles of AGR in comparison with the first and low tertiles, respectively. At multivariate analysis low levels of albumin and AGR, low tertile of AGR and high performance status remained an independent predictors of mortality. Conclusions: Low AGR was a significant predictor of long-term mortality in patients with lung adenocarcinoma. Serum albumin measurement and calculation of AGR are easily accessible and cheap to use for predicting mortality in patients with lung adenocarcinoma.

      • SCOPUSKCI등재

        The Intraoperative Corneal Pachymetry Changes during Accelerated Corneal Cross-linking in Progressive Keratoconus Patients with Thin Corneas

        Serap Yurtta er Ocak,Mehmet Serhat Mangan,Mustafa Nuri Elç , ioğ , lu 대한안과학회 2021 Korean Journal of Ophthalmology Vol.35 No.6

        Purpose: To report the intraoperative corneal pachymetry changes during accelerated corneal cross-linking (A-CXL) in progressivekeratoconus patients with thin corneas. Methods: Thirty-six eyes (mean age, 22.26 ± 4.02 years) with progressive keratoconic thin corneas (<400 μm without epithelium)who underwent A-CXL with ultraviolet (UV)-A (UVA) (9 mW/cm2) using isotonic riboflavin5-phosphate 0.1% with 1.1%hydroxypropyl methycellulose (RF-HPMC, MedioCROSS M) were included in this retrospective study. Intraoperative cornealpachymetric changes were noted before the procedure, after removal of epithelium, after RF-HPMC instillation, before andafter UV irradiation. The mean of corneal pachymetric values were compared statistically. Results: The mean corneal pachymetry reduced from 415.72 ± 29.66 to 369.50 ± 23.45 μm after removal of the epithelium(p < 0.05). After the application of RF-HPMC solution the mean thinnest corneal pachymetry (TCP) increased to 412.89 ±26.94 μm. Statistically significant increase was observed in TCP after saturation with RF-HPMC (p = 0.001). The mean cornealpachymetry before and after UVA irradiation was 419.86 ± 10.41 and 417.47 ± 8.25 μm, respectively (p > 0.05). Conclusions: Isotonic RF-HPMC lead to a significant increase in intraoperative mean TCP. RF-HPMC seems to be a favorableriboflavin option in keratoconus patients with thin corneas.

      • KCI등재

        Impact of the COVID-19 pandemic on diabetic ketoacidosis management in the pediatric intensive care unit

        Kahveci Fevzi,Ocak Buse Önen,Gün Emrah,Gurbanov Anar,Uçmak Hacer,Aslan Ayşen Durak,Ceran Ayşegül,Özen Hasan,Balaban Burak,Botan Edin,Şıklar Zeynep,Berberoğlu Merih,Kendirli Tanıl 대한중환자의학회 2023 Acute and Critical Care Vol.38 No.3

        Background: Diabetic ketoacidosis (DKA) is a common endocrine emergency in pediatric patients. Early presentation to health facilities, diagnosis, and good management in the pediatric intensive care unit (PICU) are crucial for better outcomes in children with DKA. Methods: This was a single-center, retrospective cohort study conducted between February 2015 and January 2022. Patients with DKA were divided into two groups according to pandemic status and diabetes diagnosis. Both groups were examined in two subcategories (pandemic status: pre-pandemic vs. pandemic; and diabetes diagnosis status: previously diagnosed vs. newly diagnosed).Results: The study enrolled 59 patients, and their mean age was 11±5 years. Forty (68%) had newly diagnosed type 1 diabetes mellitus (T1DM), and 61% received follow-up in the pre-pandemic period. Blood glucose, blood ketone, potassium, phosphorus, creatinine, and alanine transaminase levels were significantly higher in the new-onset T1DM group compared with the previously diagnosed group (P=0.01, P=0.02, P=0.01, P=0.039, and p=0.001, respectively). In patients with newly diagnosed T1DM, length of PICU stays were longer than in those with previously diagnosed T1DM (28.5±8.9 vs. 17.3±6.7 hours, p<0.005). The pandemic group was compared with pre-pandemic group, there was a statistically significant difference in laboratory parameters of pH, HCO3, and lactate and also Pediatric Risk Of Mortality (PRISM) III score. All patients survived, and there were no neurologic sequelae. Conclusion: Patients admitted during the pandemic period were admitted with more severe DKA and had higher PRISM III scores. During the pandemic period, there was an increase in the incidence of DKA in the participating center compared to that before the pandemic. Although the reason for this is not fully known, it could be public health presentations were not effective during the coronavirus disease 2019 (COVID-19) period.

      • SCIESCOPUSKCI등재

        Canonical Correlation Analysis for Estimation of Relationships between Sexual Maturity and Egg Production Traits upon Availability of Nutrients in Pullets

        Cankaya, Soner,Ocak, Nuh,Sungu, Murat Asian Australasian Association of Animal Productio 2008 Animal Bioscience Vol.21 No.11

        In this study, canonical correlation analysis (CCA) was applied to estimate the relationship between three different sexual maturity traits (X set: days to first egg (DFE), weight of the first egg (WFE), body weight at first egg (BWFE)) and level of nutrient intake (Y set: energy (EI) and protein intake (PI)) or the egg production traits at two different periods (Z set: number of egg (NE1 and NET) and weight of egg (WE1 and WET) from 22 to 25 (Wfirst) and 22 to 33 wk of age (Wall), respectively), which were measured from 64 egg-type pullets (Isa Brown) manipulated for time of access to energy and protein sources to onset of egg production. Partial CCA (PCCA) was used to eliminate the contribution of differences in the levels of nutrient intake to canonical variables for X and Z sets at the first production period. Estimated canonical correlation coefficients between X set and Y set (0.429, p = 0.042), X set and Z set (0.390, p = 0.007 for Wfirst) and within Z set (between Wfirst and Wall; 0.780, p<0.001), and partial canonical correlation coefficient between X set and Z set (0.415, p = 0.009) were significant. Canonical weights and loadings from CCA indicated that the BWFE had the largest contribution compared to the DFE and WFE to variation of egg number produced at two different periods. The results from PCCA indicated that the contribution of PI and EI to the degree of the correlation between canonical variables for X and Z sets were unfavourable. In conclusion, the effect of body weight at sexual maturity upon the availability of nutrients can have a higher contribution to variation of egg production in pullets if the contribution of differences in nutrient intakes to onset of egg production were eliminated.

      • SCIESCOPUSKCI등재

        Growth Performance, Meat Quality and Caecal Coliform Bacteria Count of Broiler Chicks Fed Diet with Green Tea Extract

        Erener, Guray,Ocak, Nuh,Altop, Aydin,Cankaya, Soner,Aksoy, Hasan Murat,Ozturk, Ergin Asian Australasian Association of Animal Productio 2011 Animal Bioscience Vol.24 No.8

        This study was conducted to investigate the effect of dietary green tea extract (GTE) on the performance, carcass and gastrointestinal tract (gut) traits, caecal coliform bacteria count, and pH and color (CIE $L^*$, $a^*$, and $b^*$) values of the breast muscle in broilers. A total number of 600 day-old broilers (Ross 308) was allocated to three treatments with four replicates containing 50 (25 males and 25 females) birds. The dietary treatments consisted of the basal diet as the control (0GTE) and diets with GTE at 0.1 (0.1GTE) or 0.2 (0.2GTE) g/kg. Body weights and the feed intake of broilers were measured at 1, 21 and 42 days, the feed intake was measured for different periods and the feed conversion ratio was calculated accordingly. At 42 day four birds per replicate were slaughtered for the determination of carcass and organ weights, caecal coliform bacteria count, and also quality of the breast muscle. The dietary GTE increased the body weight, feed efficiency, carcass weight and dressing percentage and decreased caecal coliform bacteria count of broilers (p<0.05). The 0GTE broilers consumed (p<0.01) less feed than the 0.1GTE birds in the entire experimental period. The relative abdominal fat weight and gut length of broilers in the 0.2GTE were tended to be lower (p<0.07) than those in the 0GTE group. The breast meat from 0.1GTE birds had a lower pH value when compared to that from 0GTE birds. The 0.1GTE broilers had lighter breast meat than 0GTE and 0.2GTE birds. The dietary GTE increased $a^*$ and $b^*$ values of the breast meat. Thus this product appeared to have a measurable impact on CIE color values of the breast meat in broilers. The results of the present study may indicate that the improved production results in the group with added GTE are directly connected with physiological mechanisms such as the regulation of the caecal micro-flora.

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