THE EXCHANGE RATE DETERMINATION IN RUSSIAN FEDERATION AND THE REPUBLIC OF KOREA

Naumova T.S.,Novicov I.A. 한국로고스경영학회 2008 한국로고스경영학회 학술발표대회논문집 Vol.2008 No.5월

Whole human exome capture for high-throughput sequencing

Naumova, Anna,Kim, Dae-Won,Nam, Seong-Hyeuk,Kim, Ryong Nam,Choi, Sang-Haeng,Park, Hong-Seog Canadian Science Publishing 2010 Genome Vol.53 No.7

<P> We captured the whole human exome by hybridization using synthesized oligonucleotides, based on a high-density microarray design, and we sequenced those captured human exons using high-throughput sequencing on a Genome Sequencer FLX instrument. Of the uniquely mapped reads, 71% fell within target regions, and these corresponded to coverage of 94% of human genes, 87% of exons, and 70% of the total base-pair length of the CCDS set. Our study provides strong evidence for the practical usefulness of this method on a genome-wide scale, showing the resequenced whole human exome database with 501 microRNAs and 307 novel SNPs. </P>

Spin valve with a composite dysprosium-based pinned layer as a tool for determining Dy nanolayer helimagnetism

L.I. Naumova,M.A. Milyaev,R.S. Zavornitsy,T.P. Krinitsina,V.V. Proglyado,V.V. Ustinov 한국물리학회 2019 Current Applied Physics Vol.19 No.11

Spin valves with nanostructure CoFe/Dy/CoFe and three-layer structures metal/Dy/metal were prepared by magnetron sputtering. The measurements of field dependences of magnetoresistance and magnetization were held at different temperatures. The changes of magnetotransport properties of spin valve containing CoFe/Dy/ CoFe structure were used for getting information on the magnetic ordering in the dysprosium layer. The characteristic changes of magnetotransport properties caused by the formation of helical ordering in dysprosium layer were detected. Special attention was paid to the estimation of Neel temperature and to the investigation of microstructure of dysprosium nanolayer.

Mobility of magnetic helicoid in holmium nano-layer

R.S. Zavornitsyn,L.I. Naumova,M.A. Milyaev,M.V. Makarova,V.V. Proglyado,I.K. Maksimova,V.V. Ustinov 한국물리학회 2020 Current Applied Physics Vol.20 No.12

Spin valves with holmium layers and three-layer structures metal/Ho/metal were prepared by magnetron sputtering. A holmium layer in the spin valves is polycrystalline with weak axial <002> texture. The structural coherence length along the hexagonal c-axis is approximately 2/5 of the total thickness of the holmium layer. Field dependences of the spin valves magnetoresistance were measured at different temperatures. Correlation was revealed between magnetic state in holmium layer and the shape of magnetoresistive curve. Deviation of magnetic moments of the reference layer and the adjacent part of holmium from the applied magnetic field was investigated. The field induced mobility of the magnetic helicoid in holmium layers was revealed.

THE METHODOLOGY OF STUDYING VIEWERS’ PERCEPTION OF AN ANIMATED CHARACTER USING PSYCHOPHYSIOLOGICAL APPROACHES

Natalia V. Galkina,Anna A. Naumova,Marina Y. Sheresheva 글로벌지식마케팅경영학회 2018 Global Marketing Conference Vol.2018 No.07

Introduction The article presents a technique for studying the perception of images of animated characters based on the application of psychophysiological methods of recording data in combination with classical sociological methods. The theoretical justification of the EEG, GSR, PPG and video-oculography methods application in testing affective stimuli is provided. The applications of the technique at various stages of creating animated characters are presented. The main advantages of the technique are noted: the ability to work with a target audience starting from the age of 3 years old and the recording of physiological data directly while viewing a stimulus material. One of the most topical objectives for the authors of animation films is the creation of animated characters, which elicits viewers’ sympathy, influences general perception of the movie and affects its distribution and final box office. The methodology that allows to study a perception of characters at different stages of its creation, from conception to final embodiment, will help authors to make changes and adjustments before moving to another technological stage, which will reduce production costs and more accurately meet the needs of the audience. The advantage of the proposed methodology on the one hand, is the efficiency of working with child audience, which is the most difficult in terms of obtaining valid information. On the other hand, it is the possibility of obtaining data directly during the perception of stimuli, which is impossible while using sociological methods. Theoretical development The EEG method is an integral component of classical neuromarketing studies of perception of audiovisual materials, allowing assessing the attractiveness and motivational component in the choice situation. A significant number of scientific publications demonstrate the correlation between the arousal of positive emotions and the activation of the left hemisphere. This is determined by the lower power of the alpha rhythm in the left frontal lobe as compared to the right one. While a person experiences negative emotion, the right frontal lobe is more active, thus, the alpha rhythm power is lower there (Rusalov, 1988, 1999; Aftanas, 2000; Vecchiato, et al. 2011; Ravaja, 2013, Harmon-Jones, et al. 2009). In our methodology the stimuli attractiveness index is calculated based on the EEG data. The high index scores are associated with positive emotions and the interest to object; low scores are associated with negative feelings and indifference. Changes in the indicators of the vegetative nervous system activity are strongly connected to an emotional manifestation; these changes are caused by anatomical and physiological conditions. Numerous studies have demonstrated that a decrease in the amplitude of the plethysmogram is observed when a person experiences negative emotions. On the contrary, an increase in the amplitude is observed during positive emotions experience (Sylvia, et al, 2008; Kreibig, et al., 2007). The emotional involvement indicator refers to the power of emotional inclusion when viewing a character. It is calculated by the registration of vegetative indices related to emotions (EDA, plethysmogram, breathing). Interest is a cognitive need to learn about what is happening on the screen; it reflects the direct interest in visual information. The understanding of interest is mostly based on the psychological researches (Izard, 1999; Silvia, 2006), however, the intensity of the parameter can correlate with objective physiological indicators based on oculomotor activity. The process of the characters’ image scanning is accompanied by the distribution of attention to individual areas of interest (Jenkin, 2001). In this methodology we allocated the areas of interest according to a different character or a separate element of the visual image of the hero. Research design The method is based on a complex approach combining neurophysiological methods of recording physiological reactions while the demonstration of animated characters’ images in combination with sociological research methods used after the stimuli demonstration. The developed technique allows the use of any audiovisual materials created at different stages of work on a character as stimuli (design of character, design of character accessories, character model in static in 2D or 3D, technological test from 10 to 30 seconds). The data was recorded via the high-speed remote binocular eye-tracking system RED250, the professional computer polygraph (PCP) “Energia” and the electroencephalograph B-AlertX24. Result and conclusion 20 images of animated movie characters were tested on 150 respondents during the research (a child audience of animated films and an adult audience with children aged 3-8 years, who make the decision to choose an animated film). A restriction for the EEG method has been found in working with children under 7 years old. At this age the analyzed rhythms are slowed down and not completely formed. The analysis of this group of respondents was focused on vegetative indices. The predicting method of perception of animated characters’ images allows us to define the evaluation parameters of the image of the animated character in terms of attractiveness, emotional involvement and interest. The methodology will be further developed and will include a differential analysis of emotional reactions by virtue of the electroencephalography method in response to the presentation of characters or video samples. The commercial use of the technique is planned for the purpose of testing characters at all stages of animation film production.

Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites

Liu, Ce Feng,Brandt, Gabriel S.,Hoang, Quyen Q.,Naumova, Natalia,Lazarevic, Vanja,Hwang, Eun Sook,Dekker, Job,Glimcher, Laurie H.,Ringe, Dagmar,Petsko, Gregory A. National Academy of Sciences 2016 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.113 No.43

<P>The transcription factor T-bet (Tbox protein expressed in T cells) is one of the master regulators of both the innate and adaptive immune responses. It plays a central role in T-cell lineage commitment, where it controls the T(H)1 response, and in gene regulation in plasma B-cells and dendritic cells. T-bet is a member of the Tbox family of transcription factors; however, T-bet coordinately regulates the expression of many more genes than other Tbox proteins. A central unresolved question is how T-bet is able to simultaneously recognize distant Tbox binding sites, which may be located thousands of base pairs away. We have determined the crystal structure of the Tbox DNA binding domain (DBD) of T-bet in complex with a palindromic DNA. The structure shows a quaternary structure in which the T-bet dimer has its DNA binding regions splayed far apart, making it impossible for a single dimer to bind both sites of the DNA palindrome. In contrast to most other Tbox proteins, a single T-bet DBD dimer binds simultaneously to identical half-sites on two independent DNA. A fluorescence-based assay confirms that T-bet dimers are able to bring two independent DNA molecules into close juxtaposition. Furthermore, chromosome conformation capture assays confirm that T-bet functions in the direct formation of chromatin loops in vitro and in vivo. The data are consistent with a looping/synapsing model for transcriptional regulation by T-bet in which a single dimer of the transcription factor can recognize and coalesce distinct genetic elements, either a promoter plus a distant regulatory element, or promoters on two different genes.</P>

Top Non-collinear Spin Valves with a Composite Free Layer for Hysteresis-free GMR Sensors

V. V. Ustinov,M. A. Milyaev,L. I. Naumova,T. P. Krinitsina,V. V. Proglyado,E. I. Patrakov 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.63 No.3

Top spin valves of Ta/[NiFe/CoFe]/Cu/CoFe/(FeMn, MnIr)/Ta composition with two types ofantiferromagnetic layers (Fe50Mn50 or Mn75Ir25) were prepared by DC magnetron sputtering. Thethree-step method for a free layer coercivity reduction has been used, namely, (i) deposition of acomposite free layer NiFe/CoFe, (ii) optimization of magnetic and nonmagnetic layer thicknesses and(iii) application of a “nearly parallel” anisotropy configuration. It is shown that the coercivity in spinvalves studied can be effectively reduced to a few tenths of an Oersted keeping the magnetoresistancehigher than 8%.