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Language Education Policies on Taiwan: A Case of Comparative Colonialism and Discourse Power
Nathaniel T. Murray(Nathaniel T. Murray ) 전남대학교 교육문제연구소 2023 New Horizons of Educational Research Vol.3 No.1
This article uses theoretical perspectives on colonialism and language planning to compare the language and education policies of two successive regimes on Taiwan: the Japanese colonial administration from 1895-1945, and the Republic of China from 1945 through the Cold War. The case of Taiwan reveals how blurry the distinction between oppression and liberation can become, and how this ambiguity can remain consistent across different regimes and geopolitical circumstances on the same population. This discussion includes some personal anecdotes from the author’s time in Taiwan, exploring how discourse is used to assert power by groups with competing cultural ideologies.
Enzymatic crosslinking-based hydrogel nanofilm for immunoisolation
Nathaniel HWANG 한국생물공학회 2021 한국생물공학회 학술대회 Vol.2021 No.10
Pancreatic β cell therapy for type 1 diabetes is limited by low cell survival rate owing to physical stress and aggressive host immune response. In this study, we demonstrate a multilayer hydrogel nanofilm caging strategy capable of protecting cells from high shear stress and reducing immune response by interfering cell-cell interaction. Hydrogel nanofilm is fabricated by monophenol-modified glycol chitosan and hyaluronic acid that cross-link each other to form a nano-thin hydrogel film on the cell surface via tyrosinase-mediated reactions. Furthermore, hydrogel nanofilm formation was conducted on mouse β cell spheroids for the islet transplantation application. The cytoprotective effect against physical stress and the immune protective effect were evaluated. Last, caged mouse β cell spheroids were transplanted into the type 1 diabetes mouse model and successfully regulated its blood glucose level. Overall, our enzymatic cross-linking-based hydrogel nanofilm caging method will provide a new platform for clinical applications of cell-based therapies.
Evolutionary insights into gymnosperm genomes resulting from the Norway spruce genome project
Nathaniel Street 한국육종학회 2013 한국육종학회 심포지엄 Vol.2013 No.07
Conifers have been the dominant tree species of many forests for more than 200 million years and are currently ecologically and economically extremely important species. Despite their importance there has, to date, been no gymnosperm genome sequence available. We produced a draft assembly of the 20 Gbp Norway spruce (Picea abies) genome. Ab initio gene prediction identified 28,354 well-supported genes representing a gene number similar to the >100 times smaller genome of Arabidopsis thaliana. Analysis of synonymous substitutions per synonymous site (Ks) identified no evidence of a recent whole-genome duplication suggesting that genome expansion resulted from other mechanisms. Repeat analysis showed that the large genome resulted from the slow and steady accumulation of a diverse set of LTR TEs that were not subsequently removed by unequal recombination, as evidenced by a high abundance of complete LTRs with few solo LTRs being identified. We performed low coverage sequencing of Pinus sylvestris, Abies sibirica, Juniperus communis, Taxus baccata and Gnetum gnemon to enable comparative analyses, revealing that the TE diversity is shared among extant conifers. Profiling of 24nt sRNAs, which are known to silence TEs via methylation, was highly tissue-specific and much lower than in other plants. We further identified numerous long (>10,000 bp) introns that arose due to TE insertions and that seem to be shared across gymnosperm species in addition to the genome containing numerous gene-like fragments, most likely representing pseudogenes. We additionally identified 13,031 spruce-specific and 9,686 conserved long non-coding RNAs, 2,719 miRNA candidates and show that the 21nt sRNA population is highly diverse, as reported previously for other conifer species. The availability of a conifer genome will enable further advances in conifer forestry and breeding as well as enabling evolutionary analysis including this previously missing group of land plants.
Musculoskeletal ultrasound: athletic injuries of the lower extremity
Nathaniel B. Meyer,Jon A Jacobson,Vivek Kalia,김성문 대한초음파의학회 2018 ULTRASONOGRAPHY Vol.37 No.3
Athletic injuries of the lower extremities are commonly encountered in clinical practice. While some pathology can be diagnosed on physical exam, others are a clinical dilemma with nonspecific symptomatology. In these situations, ultrasound imaging can be utilized as an exceptional diagnostic tool, offering unique advantages over other imaging modalities. This article will review the imaging characteristics of commonly encountered athletic injuries of the lower extremity.