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      • 배추 생육 중 토양 수용성 양이온의 경시적 변화 모니터링

        김용국(Yong gook Kim),Khok Pros,김경영(Kyoung young Kim),조현종(Hyun Jong Cho),나홍식(Hong Sik Na),한광현(Gwang Hyun Han) 한국토양비료학회 2021 한국토양비료학회 학술발표회 초록집 Vol.2021 No.11

        토양의 치환성 이온 함량이 아닌 식물체에 직접 흡수되는 수용성 이온들을 모니터링 하는 것이 중요하다. 배추가 생육하면서 토양 중 수용성 양이온들의 함량이 어떻게 변하는지 확인하고, 각 이온의 농도에 따라 그에 알맞은 처방이 이루어져야 한다. 토양 시료는 경기도 이천시의 배추 밭에서 정식 이후 16, 35, 48, 70일에 처리구별 각 3반복씩 채취하였다. 처리구는 N 기준 무처리구(Nil), NPK 비료 표준 시비량의 50% 처리구(Con), 100% 처리구(Inf), 그리고 표준 시비량의 50% 처리구에 음폐퇴비가 100%(C100), 200%(C200), 300%(C300) 추가된 처리구가 있다. 채취한 토양은 풍건 후 2 mm 체에 거르고 1:5 비율로 증류수 추출하였으며, Whatman No.2 필터를 사용하여 여과한 후 0.45 μm 실린지 필터로 재 여과하였다. 토양 추출액의 분석은 (주)테크넬 POCT 분석 키트를 사용하였다. 화학비료 처리구의 토양 중 Na의 농도비율은 생육기간 중 꾸준히 증가하는 경향이 있었다. 하지만 K의 농도비율은 시간이 지남에 따라 경시적 감소가 명확하였다. 음폐퇴비 처리구의 경우 토양 중 Na의 농도비율은 생육기간 중 증가하는 경향이었으며, 특히 퇴비 처리수준에 비례하여 높아졌다. Mg의 농도비율은 모든 처리구에서 비슷한 수준을 유지하였다. 모든 처리구에서 토양 중 K의 농도비율 감소는 Na 농도비율의 증가와 상관관계가 높았다.

      • 말기신부전 환자에서 혈액투석 전후의 QT간격분산 비교

        강대웅,정지용,윤나라,안치용,김종오,신병철,정종훈,김현리 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2

        Background: Some cases of QT interval, corrected QT interval (QTc), QT dispersion (QTd) and corrected QT dispersion (QTcd) have been reported in ESRD, but these results are variable and the influence of a hemodialysis is still controversial, In this study, we investigated the effect of hemodialysis on QT and QTc interval and QT and QTc dispersion in patients with ESRD 15 min before and 15 minute after each hemodialysis. Methods: Sixty-seven patients with ESRD (men 33 & women 34) on three-times stable hemodialysis (>3 months) were randomly enrolled. Fifty control subjects with a similar age and normal renal function were enrolled from this hospital. Routine biochemical studies were measured pre- and post dialysis, at the time of the ECG. Plasma Na+, K+, BUN, creatinine, ionized calcium and phosphate were checked. Twelve-lead electrocardiographs were performed at 10㎜/mv and 50㎜/s using a HewIett-Packard Pagewriter 100, before and after a single hemodialysis session.The QT interval was measured from the onset of the QRS complex to the end of the T wave. If the end of the T wave was not clear in a particular lead then it was excluded from analysis. When U waves were present, the end of the T wave was taken as the nadir between the T and U waves. Each QT interval was corrected for heart rate using Bazett's formula (QTc==QT/√(RR)) (ms). The difference between maximal and minimal QT interval duration was defined as QT dispersion (QTd) in each of the 12 leads. Result: This study demonstrates that QT, QTd, QTcd is higher in hemodialysis patients compared with control subjects, and QT and QTd rise postdialysis to levels comparable to those seen acutely following myocardial infarction, when patients are at greatly increased risk of potentially fatal ventricular arrhythmias, Conclusions: QT interval and QT dispersion, markers of risk for arrhythmias and sudden death, are elevated in hemodialysis patients, and rise postdialysis. QT interval and QT dispersion is an easily obtainable, noninvasive, simple, inexpensive, and widely available method of risk stratification in uremic patients receiving chronic dialysis. Additional studies are needed to clarity whether increased postdialysis QT dispersion results in an increased occurrence of arrhythmias.

      • 만성중이염의 골도청력변화

        박선홍,노용훈,이도용,나한조,김용기,최봉남,도남용 朝鮮大學校 附設 醫學硏究所 1996 The Medical Journal of Chosun University Vol.21 No.1

        We have usually experienced bone conduction impairment in chronic otitis media, but it is unclear that raised bone conduction threshold is due to the reflection of cochlear dam- age and / or Carhart effect ( an artificial elevation of bone conduction threshold due to conductive defect ) or both. The purpose of this study is to verify the influence of the artificial elevation of the bone conduction threshold in chronic otitis media and to estimate Carhart effect. A total of 336 cases of tympanoplasty with unilateral chronic otitis media without any other causes of sensorineural hearing loss was studied. The average threshold levels of the bone conduction in diseased ears ranged from 18.5dB at 4kHz to 12.1dB at 250Hz The longer duration of the disease, the larger perforation size, the more severe damage of the middle ear structure and the presence of the cholesteatoma made bone conduction threshold increased. The postoperative thresholds of bone conduction were Improved in 36 cases (40.4%) of the 89 cases that underwent operation with type I tympanoplasty technique without electrie drilling. The degree of the maximal improvement was 14.3dB at 2000Hz and the minimum was 8.8dB at 250Hz. but these result did differ from a statistically significant degree. The result suggest that the bone conduction threshold in chronic otitis media is elevated artificially by conductive defect and improved by successful reconstructive surgery.

      • 후두 및 하인두 암종에서 p53단백 발현과 Espstein-Barr Virus 검출

        최영환,도남용,나한조,이도용,노용훈,김완수,최종선 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

        Background and Objectives : When p53 cancer suppressor gene, occurs gene deletion or point mutation, malignancy develops by loss of p53 function with abnormal p53 protein. The Epstein-Barr virus (EBV) is the causative agent of certain type of lymphoma and undifferentiated nasopharyngeal carcinoma. However, the role of EBV as a causative factor in other head &eck tumors is not fully elucidated except nasopharyngeal carcinoma. This study, the author examined that p53 expression and detection rate of EBV correlate to development of laryngeal and hypopharyngeal squamous cell carcinoma(SCC) and play the possible role of prognostic indicators. Materials and Methods : Formalin-fixed, paraffin-embedded tissue specimen from 32 cases of larynx and hypopharyngeal squamous cell carcinomas were studied by immunohistochemical staining for p53 and EBV. The results of analysis were compared with clinicopathological parameters. Results : p53 expression was 56.3% (18 cases) and the detection rate of EBV was 43.6% (14 cases) of 32 cases in laryngeal and hypopharyngeal squamous cell carcinomas. p53 expression was correlate with histologic grade (p<05) only. Detection of EBV was not correlate with clinicopathological parmeters. Conclusion : These results suggest p53 expression and the detection of EBV may be related with development of laryngeal and hypopharyngeal squamous cell carcinoma. And, the expression of p53 protein can be used as a prognosticator in laryngeal and hypopharyngeal squamous cell carcinoma under certain limitation.

      • 과수병해충 피해증상 진단프로그램

        김동순,김기홍,전흥용,나승용,최용문,임명순 한국농업정보과학회 2000 농업정보과학 Vol.2 No.1

        A diagnosis program of damage-symptom caused by fruit tree pest was developed using Portable Document Format (Docucom PDF). To construct program structure, the damage patterns of plants cased by pests and the morphological rhararteristics of pests were sorted by plant organs. Diagnoses are rallied out by selecting a host species > document symptoms arranged by plant organs > comparing similar symptoms of pests using step by step menu through damage symptoms. In addition, pest information can be accessed either through the scientific or common name of the pest organism.

      • Acute inflammation reveals GABAA receptor‐mediated nociception in mouse dorsal root ganglion neurons via PGE <sub>2</sub> receptor 4 signaling

        Jang, In Jeong,Davies, Alexander J.,Akimoto, Nozomi,Back, Seung Keun,Lee, Pa Reum,Na, Heung Sik,Furue, Hidemasa,Jung, Sung Jun,Kim, Yong Ho,Oh, Seog Bae John Wiley and Sons Inc. 2017 Physiological reports Vol.5 No.8

        <P><B>Abstract</B></P><P>Gamma‐aminobutyric acid (GABA) depolarizes dorsal root ganglia (DRG) primary afferent neurons through activation of Cl<SUP>−</SUP> permeable GABAA receptors but the physiologic role of GABAA receptors in the peripheral terminals of DRG neurons remains unclear. In this study, we investigated the role of peripheral GABAA receptors in nociception using a mouse model of acute inflammation. In vivo, peripheral administration of the selective GABAA receptor agonist muscimol evoked spontaneous licking behavior, as well as spinal wide dynamic range (WDR) neuron firing, after pre‐conditioning with formalin but had no effect in saline‐treated mice. GABAA receptor‐mediated pain behavior after acute formalin treatment was abolished by the GABAA receptor blocker picrotoxin and cyclooxygenase inhibitor indomethacin. In addition, treatment with prostaglandin E2 (PGE<SUB>2</SUB>) was sufficient to reveal muscimol‐induced licking behavior. In vitro, GABA induced sub‐threshold depolarization in DRG neurons through GABAA receptor activation. Both formalin and PGE<SUB>2</SUB> potentiated GABA‐induced Ca<SUP>2+</SUP> transients and membrane depolarization in capsaicin‐sensitive nociceptive DRG neurons; these effects were blocked by the prostaglandin E2 receptor 4 (EP4) antagonist AH23848 (10 <I>μ</I>mol/L). Furthermore, potentiation of GABA responses by PGE<SUB>2</SUB> was prevented by the selective Na<SUB>v</SUB>1.8 antagonist A887826 (100 nmol/L). Although the function of the Na<SUP>+</SUP>‐K<SUP>+</SUP>‐2Cl<SUP>‐</SUP> co‐transporter NKCC1 was required to maintain the Cl<SUP>‐</SUP> ion gradient in isolated DRG neurons, NKCC1 was not required for GABAA receptor‐mediated nociceptive behavior after acute inflammation. Taken together, these results demonstrate that GABAA receptors may contribute to the excitation of peripheral sensory neurons in inflammation through a combined effect involving PGE<SUB>2</SUB>‐EP4 signaling and Na<SUP>+</SUP> channel sensitization.</P>

      • Parkinson's Disease 환자의 배뇨장애에 관한 연구

        나용길 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.2

        Parkinson's disease is one of the most common neurologic conditions causing voiding dysfunction. It is supposed that 35% to 75% of patients with Parkinson's disease will have symptoms of neurogenic voiding dysfunction. Carefully performed urodynamic investigation is the key to understanding the pathophysiology of Parkinson's disease and forms the basis for reasonable treatment. We evaluated the 20 cases of Parkinson's disease who were admitted to Chungnam National University Hospital from Aug., 1995 to Nov., 1996. Symptoms of voiding dysfunction were presented in 70% of the patients. The presenting symptoms were urgency and frequency(64%), obstructive symptoms(21%), and mixed irritative and obstructive symptoms(15%). Detrusor hyperreflexia was the most common urodynamic finding(55%), and normal(20%), impaired detrusor contractility(15%), detrusor areflxia(10%) were in order. There was a poor correlation between the parkinsonian patient's urologic symptoms and the urodynamic findings.

      • 가로변건축물의 외관디자인 특성과 인지평가에 관한 연구 : 광주광역시 충장로 1~3가를 중심으로 Focused on Choongjang-ro 1~3ga, Kwangju city

        나경천,윤지민,조용준 朝鮮大學校 建設技術硏究所 1999 建設技術硏究 Vol.19 No.2

        As the sense of value is changed into focus on quality from quantity according to the improvement of living standard, the concerns on the street landscape is greatly increasing. It means the urban value is extended to the cultural value of beauty and comfort in the formation of efficiency-centered industrial society. The city with beautiful street landscape is varied depending on the observer's viewpoint, but it must offer the pleasure with visual and thinking excitement with beautiful and ordered maintenance of the city. But, the current street has merely function of road for passage and move to destination and shows confusion and disorder in its. appearance because building owners and architects approached the street with private position for the expression of inner space rather than public position for beautiful landscape and administrative departments also developed construction and maintenance without independent landscape construction system for each street. Especially, administration focuses on the pursuit of urban convenience and efficiency, but it neglects the preservation and regeneration of local characteristics and after all the city is unified without special personality. This study reveals the physical characteristics of street landscape of Choongjang-ro, the typical pedestrian street of Kwangju city, offers the basic materials required for setting the future street plan for making it discriminated and characteristic street of Kwangju and the concrete research results are as follows. 1. The buildings at Choongiang-ro, Kwangju have mostly patterns of narrow and long front by the influence of small site location, the density of such small buildings led to discontinuance of visual stream and there is rare to back the building front for the security of commercial supremacy or secure the public site and it has low qualitative level of street landscape for pedestrians. Sufficient considerations should be given in the stage of planning the building faced with Choongiang-ro for the qualitative improvement of skeet landscape. 2. Street landscape of Choongjang-ro, Kwangju city has disordered appearance of buildings due to the confusion and disharmony of outdoor signboards for public relation and the quality of street landscape is reduced. So the design which can recognize the use of buildings in harmony with design patterns of neighboring buildings is required. That is, design should be made to make the exterior of buildings show it function and use. 3. Since the frequent interception and qualitative lowering of street landscape are resulted from the inconsistent number, size and location of all signboards attached to buildings on Choongjang-ro street, the size of outdoor signboards should be limited according to the concrete standards including the area of occupancy or front area of building of each business and the arrangement of maintenance policy of outdoor signboards is very urgent. It is found that the quality of street landscape is determined by interactions of various factors including the form of fixtures such as ad signboard, kind of business and the supply of public site as well as the form of design pattern of buildings faced with the street.

      • SCOPUSSCIEKCI등재

        변환요소에 따른 LOOPED WIRE의 탄성 변화에 관한 연구

        나용인,김상철 대한치과교정학회 1995 대한치과교정학회지 Vol.25 No.3

        Canine retraction spring과 같은 looped wire에서, 각 변환요소에 따라 변하는 탄성 정도를 알아보기 위하여, wire의 재료, 굵기, loop에 소요된 길이, loop의 모양, gabling의 여부 등 5가지의 변환요소를 설정하여, 각 wire activation시의 탄성을 range, force, stiffness등의 면에서 알아보고자 하였다. wire의 재료적인 면에서 Hi-T (Unitek Co.)와 blue Elgiloy (Rocky Mountain Orthodontics)를 선택하였으며, 굵기로는 .016˝x .022˝와 .018˝x .025˝를 선택하였다. loop 자체에 소요된 wire 길이를 15mm와 20mm의 두가지로, loop의 모양을 vertical open loop과 vertical closed loop의 두가지로, gabling의 양을 0˚와 30˚의 두가지로 하여 각각 제작하였다. 따라서 wire의 재료와 굵기, loop의 길이와 모양, gabling의 5가지 변환요소에 따라 32개군으로 구분되었으며, 각 군의 시료수는 8개씩으로, 총 256개의 시료를 대상으로 하였다. Instron(4202, Instron Co, USA)을 사용하여 각 시료의 하중변형곡선을 얻었으며 elastic limit에서의 하중과 변형을 계측하고, 그때의 stiffness(force/range)를 산출하여, ANOVA 등의 통계처리로 32개군 간의 상관성을 조사하였다. 그 결과 wire의 재료, 굵기, loop의 길이, 모양, gabling 모두가 looped wire의 하중 변형도에 유의한 영향을 미치는 것을 관찰할 수 있었으며, 탄성범위에서의 force는 Hi-T, .016˝x .022˝, loop 길이 20mm, open loop, non-gable군에서 가장 적었으며, blue Elgiloy, .018˝x .025˝, loop 길이 15mm, closed loop, non-gable군에서 가장 컸다. 탄성범위에서의 range는 Hi-T, .018˝x .025˝, loop 길이 15mm, open loop, non-gable군이 가장 적었으며, Hi-T, .016˝x .022˝, loop 길이 20mm, closed loop, gable군에서 가장 컸다. 또한 Looped wire의 탄성에 가장 큰 영향을 미치는 변환요소는 loop의 모양과 길이였으며, gabling의 영향이 가장 적었다. The purpose of this study was to evaluate and compare the effect of the variable factors of wire on the elastic properties of looped rectangular wire. Five variable factors were presented - material(Hi-T, blue Elgiloy), wire size(016˝x .022˝, .018˝x .025˝), loop length(15mm, 20mm), loop configuration(open loop, closed loop), gabling (non-gable, gable). So, the total 256 specimens were divided into 32 groups, and each of those was pulled on Instron testing machine. The load-deflection curve of each wire was obtained, from which force, range in elastic limit, and stiffness were computed and analyzed statistically. The results were obtained as follows : 1. All of the variable factors - wire material, size, loop length, loop configuration, and gabling - took a significant effect on load-deflection rate of looped wire. 2. The force at elastic limit was the smallest in the group of Hi-T, 016˝x.022˝, 20mm loop length, open loop, non-gable, and the largest in the group of blue Elgiloy, .018˝x.025˝, 15mm loop length, closed loop, non-gable. 3. The range at elastic limit was the smallest in the group of Hi-T, .018˝x.025˝, 15mm loop length, open loop, non-gable, and the largest in the group of HI-T, 016˝x.022˝, 20mm loop length, closed loop, gable. 4. Loop configuration and loop length were most effective factors on the elastic properties of looped wires, and gabling was the least effective.

      • 골반경수술 146예에 대한 임상적 고찰

        나준희,김용만,남주현,김영탁,김종혁,목정은 울산대학교 의과대학 1995 울산의대학술지 Vol.4 No.2

        Pelviscopic surgery has been reported to have minimal tissue damage and bleeding, and to reduce cost and recovery time for patients undergoing a variety of procedures. The field of gynecologic operations that can be performed by pelviscopic procedures has expanded rapidly. This report is a retrospective review of 146 cases of pelviscopic surgery from January, 1991 to February 1996 to evaluate the efficacy of pelviscopic surgery in gynecologic patients. The results of this review were summarized as follows; 1. The majority of patients was between 21 and 40 years of age(84.2%), mean age was 33.1 years. 2. Preoperative clinical indications were adnexal mass 77 cases(52.7%), ectopic pregnancy 48 cases(33.9%), uterine myoma 9 cases(6.2%), and etc. 3. Types of surgery were salpingectomy 43 cases(29.5%), salpingoophorectomy 41cases(28.1%), LAVH 9 cases(6.2%) and etc. 4. The previous operation history was found in 34 cases(23.3%), and the type of previous operation were Cesarean section 11 cases(32.4%), appendectomy 10 cases(29.4%), and there were 5 cases of previous history of ectopic pregnancy. 5. The mean duration of hospitalization was 5.8 days.

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