Studies on the Effects of Biomedicinal Agents on Serum Concentration of Ca2+ , P and ALP Activity in Osteoporosis-Induced Rats

Sang-keun Kim,Myung-hun Lee,Man-hee Rhee 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2

on the Effects of Biomedicinal Agents on Serum Concentration of Ca2+, P andALP Activity in Osteoporosis-Induced RatsSang-keun Kim, Myung-hun Lee1 and Man-hee Rhee2College of Veterinary Medicine, Chungnam National University, 220 Gungdong, Yusong-Gu, Daejeon 305-764, Korea1National Veterinary Research and Quarantine Service, Anyang 430-824, Korea2College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, KoreaReceived April 3, 2003 / Accepted July 9, 2003J. Vet. Sci. (2003), 4(2), 151-154JOURNAL OFVeterinaryScience*Corresponding author: Sang-keun Kim Dept. of Vet. Med., Chungnam National University, Daejeon 305764, Korea Tel: +82-42-821-6754, Fax: +82-42-821-6754 E.-mail: kskkim@cnu.ac.kr

大田市圈內의 河川 汚染度(1981)

明平根,成洛道,朴勝熙,鄭憲俊,吳仁敎 순천향대학교 1982 논문집 Vol.5 No.4

An investigation of the water quality for the streams of Daejon area in Chung-nam province, korea, was conducted from January to December 1981. By this analysis of water quality for the streams of Daejon area, annual mean values of BOD: 49.3㎎/l, COD: 33.4㎎/l, DO: 7.5㎎/l, SS: 39.1㎎/l were determined respectively and those values of parameters were comparatively high. The increasing order of the water pollution for the streams of Daejon area was as follows; confluence place Daewha-Dang (D)> Yudeung Stream (B)> Daejon Stream (A)> Gab Stream (C). Therefore, it suggest that the water pollution of the streams of Daejon area have greatly influenced upon the water quality of Kum River in Chungnam and Jon-buk province.

초경 시작 시기가 여성 정신분열병 환자의 병의 경과에 미치는 영향

김진훈,윤선욱,배명지,임선진,정은기,장동원 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.5

Objectives : The protective effects of estrogen against the development of schizophrenia have been investigated in various perspectives, Previous studies showed patients with earlier age of menarche had later onset of schizophrenia and less frequent admissions. This study was performed to evaluate the effect of the age of menarche on subsequent courses including hospitalizations, suicidal attempts, Physical harm to others, and psychotic symptoms in women with schizophrenia. Methods : Self-report menarche age, onset of psychotic symptoms, and clinical status were collected in a sample of 108 Premenopausal women with the diagnosis of schizophrenia. Results : There was significant correlation between the age of menarche and the frequency of admissions (r=.321, p=.006). Also, Patients with history of physical harms to others showed later age of menarche than those without (t=2.025, df=106, p=.045). Conclusion : In women with schizophrenia, the age of onset of menarche affects subsequent courses indicated by frequency of admissions and violent behaviors. It is suggested that identifying the age of menarche might be helpful to predict the courses in women with schizophrenia. Further investigations regarding the relationship between estrogen and the courses of Schizophrenia in women are needed.

R&D에서의 공공/민간 파트너십에 관한 연구

강명헌 단국대학교 산업연구소 2000 산업연구 Vol.22 No.-

소설〈혼불〉에 나타난 통과의례와 복식 분석(Ⅰ)

柳志憲,韓明淑 服飾文化學會 1997 服飾文化硏究 Vol.5 No.2

韓國電子産業의 構造 및 總要素生産性 分析

姜明憲 단국대학교 산업연구소 1988 산업연구 Vol.11 No.-

고 사구체전 저항의 신장에서 수출소동맥 이완에 대한 신혈역학적 반응 : 수학적 접근

양훈모,주명찬 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.1

To progressive increases in efferent arteriolar resistance (RE), GFR responds with an initial increase followed by a decrease. The biphasic response implies that the response of GFR to RE varies depending on the renal hemodynamic conditions. We studied, with a glomerular model, the mechanism of deterioration of renal function during angiotensin I converting enzyme inhibitor (ACEI) in the kidney with renal artery stenosis. The glomerular model was based on a simulation of flow along a glomerular capillary with negligible resistance and uniform ultrafiltration coefficient (kf, 0.09 nl·sec-1·mmHg-1). The control preglomerular resistance (RPRE) and RE were 0.071 and 0.081 mmHg·min·ml-1, respectively. The effect of renal artery stenosis is to increase RPRE by inserting a fixed stenotic resistance in series with the afferent arteriolar resistance, and RPRE which is the sum of the resistances of stenosed renal artery and afferent arteriole is increased in the kidney with stenosed renal artery. Since the higher RPRE is associated with greater reduction in GFR in response to reduction in RE, the kidney with stenosed renal artery will respond with severer decrease in GFR to postglomerular vasodilation. In addition, the preglomerular vasodilation which accounts for the major compensatory response to renal hypotension in the normal kidney becomes less and less effective in recovering PG and GFR during a decrease in renal artery pressure as the resistance caused by the stenosis becomes greater. The model has shown that these two factors contributed to the greater reduction in GFR (34ml·min-1 during renal artery stenosis vs. 46.5ml·min-1 during control) despite an increase in kf (40%) during ACEI in the kidney with renal artery stenosis (resistance; 0.082 mmHg·min·ml-1). In conclusion, severer deterioration of renal function in response to ACEI administration in the kidney with renal artery stenosis results from the reduced ability of RPRE to decrease in response to hypotension and the increased sensitivity of GFR to a decrease in RE when RPRE is increased.

飽和度에 따른 三軸壓縮强度의 特性 硏究

최명진,고영현,상현규,김팔규 忠南大學校 産業技術硏究所 1999 산업기술연구논문집 Vol.14 No.1

Lately,the study of the soil behavior and mainly related to the degree of saturation. But most soils in the ground actually exist not in the saturated condition but in the unsaturated one. The foundation bases adn the soils used for construction material are almost such unsaturated soil as granite soil in Korea. The griaxial test are used in order to examine the strength characters of the unsaturated soil in this research, reappeared in-situ field condition for the undaturated soil through the UU-test in the laboratory and examined strength character. The variation of shear strength accrding to the increase of the degree of saturation is measured as the result and the proposed formula are suggested

생쥐 대장 평활근 세포에서 내향 정류성 칼륨 전류의 특성 연구

이은주,김명,정명섭,조향훈,김기훈,하현철,김준수,최석,전제열 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2

Objectives: K^(+) channels play an important role in regulating cellular excitability. The aim of this study was to know whether or not inward rectifier K^(+) channel exists in colonic smooth muscle cells. Methods: Mouse colonic smooth muscle cells were isolated using collagenase, and then we recorded their membrane currents using a whole-cell patch clamp technique. Results: With 90 mM K^(+) in bath, hyperpolarization-induced inward currents from -120 mV to 20 mV with 400 ms duration at a holding potential of -10 mV showed rapid activation, inactivation and inward rectification. The inactivation showed single exponential time course. Reduction of external K^(+) to 60 mM decreased the amplitudes of the currents in whole test voltage range and shifted the reversal potential to more negative potential. The inactivation process and peak currents of hyperpolarization-induced inward currents were not affected by removing external Na^(+). External Ba^(+) blocked hyperpolarization-induced inward currents by dose-dependent manner and pure Ba^(+)-sensitive currents showed strong inward rectification. Cs^(+) also suppressed hyper- polarization-induced inward currents. Ba^(+) and Cs^(+)-induced inhibitiOn of hyperpolarization-induced inward currents was voltage-dependent, and the extent of inhibition increasing with membrane hyperpolarization. Conclusions: These results suggest that inward rectifier KU channels may exist in proximal colonic smooth muscle and may play an important role in regulating membrane potential.

꿈 分析을 통한 精神治療 修練

申明淑,姜錫憲 大韓神經精神醫學會 1983 신경정신의학 Vol.22 No.2

정신치료의 修練을 目的으로 著者들을 포함한 7명의 수련의가 Supervisor의 주제하에 1981년 3월부터 11월까지 8개월간 慶北醫大 神經精神醫學 敎實에서 週1回 90分間 19回의 꿈 分析時間을 시도하였다. 19回의 錄音된 꿈 분석 資料를 정리하고 參加者들의 反應을 設問紙로 조사하고 集團討論을 거쳐 다음의 결과를 要約한다. 參加者 전원은 꿈 분석시간이 정서적으로 유익한 同察精神治療의 經驗으로 느꼈다. 참여자들의 轉移現象은 權威者를 둘러싼 兩價感情이 주류를 이루었고 이는 꿈 분석을 주도한 Supervisor의 現實的 役割이 크게 작용함을 알았다. Supervisor는 자신의 逆轉移感精을 과다한 꿈 解釋으로 방어할려는 경향이 있음을 자각하게 되었다. 꿈 분석시간에 참가한 수련의 전원은 정신치료의 基本槪念 습득에 도움이 되었다고 反應하였고 특히 꿈 해석의 技法을 배우는데 유익하였다고 보고하였다. 19회의 꿈 분석시간에 보고된 전체꿈 수는 122개였으며 이들 꿈을 몇가지의 주제별로 분류해보면 依存·獨立의 葛騰(26%), 敵愾心과 功擊心의 表現(21%), 無力 또는 無能感(15%), 兩價感情(8%), 排斥感(5%), 憂혈(3%) 등이었다. 꿈 내용에 있어서 수련기관이 그 배경으로 등장하는 경우가 전체 꿈의 32%나 되었으며 따라서 수련의의 정신과 수련에 따른 갈등의 一面을 表現, 解消되거나 現實的 調整이 가능한 예가 많았다. 이상에서 볼때 集團 꿈 分析時間이 정신치료 수련에 유용하게 利用될 수 있다고 본다.정신치료의 修練을 目的으로 著者들을 포함한 7명의 수련의가 Supervisor의 주제하에 1981년 3월부터 11월까지 8개월간 慶北醫大 神經精神醫學 敎實에서 週1回 90分間 19回의 꿈 分析時間을 시도하였다. 19回의 錄音된 꿈 분석 資料를 정리하고 參加者들의 反應을 設問紙로 조사하고 集團討論을 거쳐 다음의 결과를 要約한다. 參加者 전원은 꿈 분석시간이 정서적으로 유익한 同察精神治療의 經驗으로 느꼈다. 참여자들의 轉移現象은 權威者를 둘러싼 兩價感情이 주류를 이루었고 이는 꿈 분석을 주도한 Supervisor의 現實的 役割이 크게 작용함을 알았다. Supervisor는 자신의 逆轉移感精을 과다한 꿈 解釋으로 방어할려는 경향이 있음을 자각하게 되었다. 꿈 분석시간에 참가한 수련의 전원은 정신치료의 基本槪念 습득에 도움이 되었다고 反應하였고 특히 꿈 해석의 技法을 배우는데 유익하였다고 보고하였다. 19회의 꿈 분석시간에 보고된 전체꿈 수는 122개였으며 이들 꿈을 몇가지의 주제별로 분류해보면 依存·獨立의 葛騰(26%), 敵愾心과 功擊心의 表現(21%), 無力 또는 無能感(15%), 兩價感情(8%), 排斥感(5%), 憂鬱(3%) 등이었다. 꿈 내용에 있어서 수련기관이 그 배경으로 등장하는 경우가 전체 꿈의 32%나 되었으며 따라서 수련의의 정신과 수련에 따른 갈등의 一面을 表現, 解消되거나 現實的 調整이 가능한 예가 많았다. 이상에서 볼때 集團 꿈 分析時間이 정신치료 수련에 유용하게 利用될 수 있다고 본다. Seven psychiatric residents have experienced 19 successive series of group dream sessions as a method of psychotherapy training. The dream sessions were conducted by the senior author (psychotherapy supervisor) in the department of neuropsychiatry, Kyung-Pook University Hospital, and the sessions lasted for 8 months' duration from March to November, 1981. Each dream session ran for 90 minutes on the weekly one time basis. Dream sessions primarily consisted of reporting manifest dreams of all participants, of freely associating to the dream images, and of discussing the materials. The supervisor tried to interpret the dream material psychotherapeutically. All dream sessions were tape-recorded. The presupposed purpose of group dream sessions was to experience the psychotherapeutic situation and to understand basic concepts of dynamic psychotherapy as well as to have insight into their own emotional problems. To evaluate the effects of dream sessions, the authors reviewed all the recordings of the dream sessions after 10 months after the termination of the sessions. In addition, the authors had individual interviews and one group discussion with all participants to evaluate the after effects. A questionnaire composed of 32 items was applied to the participants of analyzing the data of the experience. The results could be summarized as follows; All participants of the group dream session agreed that the experience was a kind of insight group psychotherapy with highly emotional atmosphere; each session had been rather terse and characterized by lack of verbal exchange, but was followed by extra group talking when the supervisor was absent. Main subjects of and emotional conflicts among the participants. The nature of the transference of the participants was colored by the authority problem toward the supervisor; the reason for this could be partly explained by the fact that the supervisor also serves as a real figure (director of the psychiatric department). The supervisor himself gained insight into his own countertransference of domineering tendency, which manifested in the form of excessive and sometimes rather critical interpretations. The total number of manifest dreams reported during 19 sessions was 122, which counted 1 dream for each member in a session. As to the contents of the manifest dreams, the author could identify several categories of central themes; dependence-independence conflicts(26%), expression of hostility and aggressive impulse(21%), helplessness(15%), overt ambivalence(8%), feeling of rejection(5%), depression(3%), and others. It is interesting that the pictorial background in the manifest dreams frequently showed the training hospital; around one third of all dreams. Accordingly, the members could express various emotional conflicts of the psychiatric training and the conflicts could by worked through. Finally, the reaction to the dream session was particulary impressive in that their previous concepts about psychotherapy became vividly clear from their own experience of dream sessions; in terms of the basic concepts of the unconsious, transference, resistence and others. The authors felt that the group dream sessions could be a useful tool for learning and teaching dynamic psychotherapy.