경구면역을 통한 항원 특이적 IgA 항체 합성에 있어 Cholera Toxin과 Alginate-Microsphere의 효과

송민형,유진수,권명상,성승룡,김용희,권익찬,정서영,양재명,김평현 大韓免疫學會 1996 大韓免疫學會誌 Vol.18 No.3

Secretory (S-IgA) isotype antibody (Ab) is known to play an essential role in the primary defense against various infectious agents in mucosal tissue. However, it has been mostly unsuccessful in the induction of antigen (Ag)-specific IgA Ab response in this site by peroral vaccination. In the present study, we investigated the effect of cholera toxin (CI) as a mucosal adjuvant and alginates-microspheres as a carrier on BSA-specific IgA Ab response in gut-associated lymphoid tissue`(GALT). Peroral immunization of BSA plus CT conferred a great BSA-specific IgA response but IgG response on intestinal fluid (IF). In contrast, intraperitoneal immunization of BSA with Freund's adjuvant readily induced BSA-specific IgG response but IgA response in IF. Further, number of CT specific IgA-secreting cells was substantially increased in mesenteric lymph node when CT-encapsulated-VI alginates-microspheres was administered perorally. Taken together, these results indicate that peroral immunization of soluble antigen in combination of CT or microspheres significantly enhances antigen-specific IgA response in GALT.

과수병해충 피해증상 진단프로그램

김동순,김기홍,전흥용,나승용,최용문,임명순 한국농업정보과학회 2000 농업정보과학 Vol.2 No.1

A diagnosis program of damage-symptom caused by fruit tree pest was developed using Portable Document Format (Docucom PDF). To construct program structure, the damage patterns of plants cased by pests and the morphological rhararteristics of pests were sorted by plant organs. Diagnoses are rallied out by selecting a host species > document symptoms arranged by plant organs > comparing similar symptoms of pests using step by step menu through damage symptoms. In addition, pest information can be accessed either through the scientific or common name of the pest organism.

국내건설공사 사례를 기준한 건설클레임 집중관리 대상선정 프로세스 모델

강명용,민경석 남서울대학교 2007 남서울대학교 논문집 Vol.13 No.3

ABSTRACT : Recently, construction claims have been increased for protecting the rights of construction participants and obtaining the profit of construction projects.There are a lot of unpredictable and uncertain factors in construction projectand these fators cannot be stipulated clearly in contracts. For this reason, a chance of construction claims and disputes is always latent and construction disputes are occurred frequently while construction project are accomplished. Sound contractual relationship between owners and contractors can be maintained and contract clauses can be modified reasonably through construction claims. Although construction claims have theses good effects, construction claims can induce owners and contractors to an antagonism and lead to vast time and economic damages when construction claims develop disputes such as an arbiration and a litigation.

건강한 한국인에서의 배변 조영술 소견

나용호,장명규,김태현,김형언,유광현,진경민 大韓消化器病學會 1995 大韓消化器病學會誌 Vol.27 No.3

저수준 문자 영상의 인식에 관한 연구

공용해,김명숙,최인석 순천향대학교 부설 산업기술연구소 1999 순천향 산업기술연구소논문집 Vol.5 No.2

Low quality character images include a lot of variousness and noises, so the use of a single classifier is difficult to achieve a high recognition performance. For this, we experimented various feature extraction methods suitable for low quality images and constructed a classifier-pair that uses two complementary features. The experimental result using this classifier-pair was very effective for the recognition of low quality character images.

Chromobacterium chocolatum에서의 lipase유전자분리 및 발현

안용현,장지명 단국대학교 2000 論文集 Vol.35 No.-

A kind of vitamin B group. (+)-biotin has been known to have an influence on the growth of an organism and used for feeding material. Biotin has been synthesized by chemical method, and then crystallized with d-ephedrine to get the optically pure form. Lipase have been used for the resolution of chiral compound from racemic mixture. One of intermediates in the biotin synthesis is a diester which is a meso compound. Chromobacterium chocolatum has applied to hydrolyze one methyl ester group. The mono ester was successfully used for the synthesis of (+)-biotin as well as high optical purity. The goal of this research is the genetic cloning of lipase which hydrolyze the dimethyl ester from Chromobacterium chocolatum and identify its enzymatic reaction.

Poly-β(1,4)-D-glucosamine-g-polyethyleneoxide의 합성 및 물성에 관한 연구

주상명,장광태,성용길 동국대학교 자연과학연구원 1995 자연과학연구 논문집 Vol.15 No.-

Poly-β(1,4)-D-glucosamine derived from poly-β(1,4)-N-acetyl-D-glucosamine by treating with alkaline solution has been reported to be a promising polymer not only in the chemical field but also in biomedical area. Poly-β(1,4)-D-glucosamine used in this experiment was seen about 93 percentage of degree of deacetylation by heterogeneous alkaline soultion. Poly-β(1,4)-D-glucosamine-g-polyethyleneoxide was synthesized by homogeneous method. Various molecular weights of polyethyleneoxide as a hydrophilic and flexible spacer were introduced to Poly-β(1,4)-D-glucosamine to produce Poly-β(1,4)-D-glucosamine-g-polyethyleneoxide. The synthesized copolymers are characterized by FT-IR, elemental analysis, thermogravimetric analyzer, and differential scanning calorimetry.

1980년대 항공기 사고에 대한 Database 연구

황명신,송용규 한국항공대학교 1994 論文集 Vol.32 No.-

본 연구는 1980년에서 1989년까지 발생된 전세계 각종 항공기 사고에 대하여 사고관련 자료들을 취합하여 사고관련 database를 구축하고, 이들 자료들로 부터 항공기 사고관련 원인을 분석하여 항공기 사고 발생을 방지할 수 있는 자료들을 제공하기 위한 것이다. In this paper we present the Aircraft Accident Database which had been occurred from 1980 to 1989. From this Database, we analyse the possible Aircraft Accident reasons, and represent some special topics on accident.

이산대수문제에 기반한 그룹 비밀키 분배 및 갱신프로토콜

오명옥,김성열,정일용 조선대학교 전자정보통신연구소 2001 電子情報通信硏究所論文誌 Vol.4 No.2

본 논문에서는 ID 보안 기술에 기반을 둔 디지털서명, 키분배 기법을 이용하여 그룹 비밀키의 분배와 갱신을 위한 효율적인 프로토콜을 제안한다. 제안된 프로토콜의 안전성은 이산대수 어려움에 근거하고 있으며 단말기의 저장능력과 처리의 능력이 적을 경우도 적절하게 운영될 수 있고, 그룹 내에서 제외하고자하는 통화자가 동시에 여러 명일 경우에도 적용할 수 있다. 또한 통화자의 변동 없이 그룹 비밀키를 변경하고자 하는 경우에도 용이하게 키를 갱신할 수 있도록 설계되었다

파라콰트 중독에서의 항산화치료

권운용,조유환,송형곤,김명천,이중의,서길준,윤여규 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4

Background: Paraquat causes severe tissue toxicity when ingested, but has no effective treatment modality. We have shown that high dose vitamin C has effective antioxidant activities against the paraquat intoxication in a previous animal experiment. This study was designed to evaluate the effect of antioxidant therapy with high dose vitamin C and vitamin E in human cases of paraquat intoxication. Methods: From August 1999 to August 2001, 19 paraquat intoxication patients who visited the emergency department of the Seoul National University Hospital and the Kyounghee University Hospital were enrolled to this study. They were devided into two groups, a control group(9 patients) and a study group(10 patients). The control group received only conservative managements including gastro-intestinal decontaminati-on. The study group received conservative managements plus the antioxidant therapy which was composed of vitamin C 24 gm/day intravenously and 20 gm/day orally, and vitamin E 1.6 gm/day orally. Results: In the study group, 5 of 10 patients(50%) survived, but all patients of the control group died(p=0.003). There were no significant differences in age, sex, and usage of gastric lavage and activated charcoal between the two groups. Difference in ingested amount of paraquat between the two groups could not be analyzed due to the inexact and subjective measuring methods based on patients' histories. Conclusion: Antioxidant therapy with high dose vitamin C and vitamin E is effective in vival rate in paraquat intoxicated patients.