Conceptual Study for Tissue-Regenerative Biodegradable Magnesium Implant Integrated with Nitric Oxide-Releasing Nanofi bers

Jin‑Kyung Jeon,Hyunseon Seo,Jimin Park,Soo Ji Son,Yeong Rim Kim,Eun Shil Kim,Jong Woong Park,Woong‑Gyo Jung,Hojeong Jeon,Yu‑Chan Kim,Hyun‑Kwang Seok,Jae Ho Shin,Myoung‑Ryul Ok 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.4

The excessive initial corrosion rate of Mg is a critical limitation in the clinical application of biodegradable Mg implantsbecause the device loses its fi xation strength before the fractured bone heals. This study suggests a new approach to overcomethis hurdle by accelerating tissue regeneration instead of delaying the implant biodegradation. As angiogenesis is anessential process in early bone regeneration, a Mg implant coated with electrospun nanofi bers containing nitric oxide (NO),which physiologically promotes angiogenesis, is designed. The integrated device enables adjustable amounts of NO to bestored on the NO donor-conjugated nanofi ber coating, stably delivered, and released to the fractured bone tissue near theimplanted sites. An in vitro corrosion test reveals no adverse eff ect of the released NO on the corrosion behavior of the Mgimplant. Simultaneously, the optimal concentration level of NO released from the implant signifi cantly enhances tube networkformation of human umbilical vein endothelial cells without any cytotoxicity problem. This indicates that angiogenesis canbe accelerated by combining NO-releasing nanofi bers with a Mg implant. With its proven feasibility, the proposed approachcould be a novel solution for the initial stability problem of biodegradable Mg implants, leading to successful bone fi xation.

Distal Femoral Medial Opening Wedge Osteotomy for Post-Traumatic, Distal Femoral Varus Deformity

Myoung­Soo Cha,송시영,Koo-Hyun Jung,Young-­Jin Seo 대한슬관절학회 2019 대한슬관절학회지 Vol.31 No.1

Restoration of neutral mechanical alignment of the lower limb is an important factor in the treatment of unicompartmental arthrosis. Traditionally, medial opening wedge high tibial osteotomy has been widely performed to correct varus malalignment with unicompartmental arthrosis. However, an ideal indication for the high tibial osteotomy is the knee with metaphyseal tibial varus malalignment. The basic principle of corrective osteotomy is performing an osteotomy at the center of the deformity to prevent abnormal joint line obliquity. If pathologic distal femoral varus deformity is the cause of genu varum, the osteotomy should be performed in the distal femur. Reports of medial opening wedge distal femoral osteotomy (DFO) to correct varus malalignment are rare. We present a case of this very rare and challenging condition in a 47­year­old male, which was successfully treated by medial opening wedge DFO.

폴리에스테르 섬유 감량시스템용 프로세서 타이트레이터 개발

조진호,이흥락,이종현,김명남,구성모,김무영,진경찬,유병희,강민수,김국진 경북대학교 센서기술연구소 1993 연차보고서 Vol.1993 No.-

폴리에스테르 섬유 감량시스템의 제어를 위해서는 처리조 내에서 감량되는 섬유가 목표 감량치에 도달했는지를 판단해 주는 장치가 필요하다. 본 연구에서는 가성소다용액의 초농도 및 섬유 감량 정도의 정확한 측정과 감량 종료시간의 산출 및 이에 따른 종료신호를 발생할 수 있는 폴리에스테르 섬유 감량기 전용의 자동적정장치를 개발하였다. To control caustic soda treatment system for the polyester fabric reduction, we need the device to determine that the fabric has been arrived target reduction value. In this study, we develope an automatic process titrator for the caustic soda treatment system. Major functions of the target titrating system are accurate measurements of the caustic soda concentration and then producing the end point signal for caustic soda treatment system.

하치조신경 및 설신경 손상 평가를 위한 한국인 정상 성인의 하순-이부 및 혀의 감각 조사

이종호,이세영,송승일,이은진,안강민,김성민,명훈,황순정,서병무,최진영,정필훈,김명진 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.2

In the head and neck area, there are so many sensory nerves, which are sometimes injuried iatrogenically or inadvertently so that involved patients complained of the loss of sensations. In such cases, it is important to judge the degree of injuries and regeneration of nerve for better diagnosis and treatment. Seddon and Sunderland's classification, which is commomly used, is focused on histological change and nerve conduction. As times goes by, it is difficult to access patient's sensory disturbance by this method. Until now, so many methods such as contract threshold, direction, two-point discrimination, pin prick, thermal discrimination and current perception threshold have been introduced for sensory evaluation. However, there hasn't been enough information regarding each methodology nor integrated standard methodology for the measurement. the purpose of this study is to get Korean adult normative sensory values of lower lip,chin and tongue using modified methods of contact thershold, ditection, two point discrimination, pin prick, thermal discrimination and assess degree of regeneration of sensory nerve damage.

비복신경이식을 이용한 긴 거리의 말초신경 결손부 수복

이종호,이세영,김명진,이은진,안강민,김성민,최원재,명훈,황순정,서병무,최진영,정필훈 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.2

The surgery of oral and maxillofacial area poses the risk of cranial nerve damage such as trigeminal nerve or facial nerve. Inferior alveolar nerve is prone to damage in the third molar extraction, implant installation, orthognathic surgery, open reduction and rigid fixation, and tumor ablation surgery. On the other hands,facial nerve is likely to be damaged or sacrificed with trauma or parotidectomy. In case of inferior alveolar nerve injury, the incidence is reported to be about 1.3%. The nerve function will almost recover in minimal damage, but it won't recover at last in total damage of a part of nerve unit. In latter cases, nerve regeneration in intended by allograft as nerve substitute or various route of merve condit. But the recovery with autograft is believed to be most relialbe mrthod in the rapair of long-span(longer than 15㎜)nerve defect. We have performed autologous sural nerve graft in the repair of nerve defect, which is caused by resection of benign or malignant tumor. Hereby we report the method of nerve harvesting, recovery of defected peripheral nerve and the complications of donor site with the discussion of sural nerve anatomy.

진행된 HIV 감염 환자에서 십이지장의 미란성 병변으로 발현한 Mycobacterium genavense 감염 1예

진상만,박종선,김홍빈,오명돈,최강원,김희연,국윤호,김남중 대한감염학회 2007 감염과 화학요법 Vol.39 No.4

Mycobacterium genauense는 최근에 알려진 미코박테륨으로서, 식욕 부진, 체중 감소, 설사, 림프절 병증 등 파종성 Myocobacterium avium-intracellulare complex 감염과 유사한 임상상을 보이며, 위장관 침범을 잘 하는 것으로 알려져 있으나 아직 국내에서 증례는 보고된 바가 없다. 저자들은 진행된 HIV 감염 환자에서 십이지장의 미란성 병변으로 발현한 Mycobacterium genavense 감염 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. 환자는 상복부 동통과 발열, 설사로 내원하였다. 십이지장의 미란성 병변에서 시행한 조직검사에서 항산균이 가득 차있는 거품세포가 관찰되었으며, 이 검체에서 16S rRNA 유전자의 중합연쇄반응 검사를 시행하여 Mycobacterium genavense를 확인하였다. Mycobacterium genavense, first identified in 1990, is known as a pathogen that mimics disseminated Myocobacterium avium-intracellulare complex (MAC) infection with particular propensity for the gastrointestinal tract. In Korea, no case with the organism has been reported. Herein we report a case of Mycobacterium genavense infection that manifested with erosive lesion of duodenum in a patient with acquired immune deficiency syndrome. The patient presented with epigastric pain and fever, diarrhea. Duodenal biopsy showed histiocytic infiltration with numerous acid-fast bacilli. Identification of the mycobacterial isolate by the polymerase chain reaction restriction analysis of 16S rRNA gene revealed Mycobacterium genavense.

SVD 알고리즘 및 HMM을 이용한 얼굴 및 눈 패턴 검출

진경찬,김명남,신장규,손병기,조진호 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

The studies about automatic pattern detection of the eye and face from the human image acquired by the CCD image sensor have good applicabilities in the industry, home automation, and data communication field. In general, pattern detection method consists of feature based matching and template matching. In feature based matching, the feature vector is extracted with DLM(dynamic linking matching), EBGM(elastic bunch graph matching), HMM(hidden markov model) matching and knowledge based matching using statistical characteristics. In template matching, in general, the template vector is extracted with PCA(principal component analysis). When these method applied in the face and eye detection, each method has its own merits and some disadvantage. Therefore, by combined utilization of SVD(singular value decomposition) and HMM algorithm, is expected that we can selectively make use of each methods advantage and it result in improved detection accuracy. In this paper, we proposed the method for face and eye detection, which was combined by the two algorithms, to be suitable for the high speed image processing using DSP chip or microprocessor. In the beginning, template matching was followed by a template extraction using batch SVD algorithm and then face pattern was classified and recognized by HMM algorithm which is one of feature based matching technique. Finally, eye pattern detection was performed by pattern search neural network utilizing eigeneye image.

투기, 구기, 라켓경기 선수의 피하지방 두께와 근질량 비교분석

최명진,안세옥 경희대학교 사회체육연구소 1996 體育科學論叢 Vol.- No.9

The purpose of this study was to discriminate the characteristics of muscle mass and skinfold thickness in made cdlesiate athletes 120 athletes from three parts of sport events who were 20∼22 years old (mean 21 age years). with ape of 21 years ANOVA. swbjects were 120 1. The maximal upper arm girth means corrected for the tricep skinfold thickness were ranged from 26.05 for the taekwondo to 31.41 for the judo. Judo was one of the greatest maximal upper arm girth means corrected for the tricep skinfold thickness in all sports (rugby, table tennis, handball, badminton, taekwondo). By scheffe test, judo and rugby is different from other sports. 2. The maximal forearm girth means were ranged from 26.13 for the taekwondo to 29.28 for the judo. Judo was one of the greatest maximal forearm arm girth means corrected for the tricep skinfold thickness in all sports (rugby, table tennis, handball, badminton, taekwondo). By scheffe test, rugby was different from taekwondo, Judo was different from taekwondo, handball, badminton, table tennis. 3. The mid thigh girth means corrected for the front thigh skinfold thickness were ranged from 50.75 for the table tennis to 57.09 for the rugby. Rugby was one of the greatest maximal mid thigh girth means corrected for the tricep skinfold thickness in all sports (rugby, table tennis, handball, badminton, taekwondo). By scheffe test, judo was different from table tennis. Rugby was different from taekwondo, handball, badminton, table tennis. 4. The maximal calf girth means corrected for the calf skinfold thickness were ranged from 34.69 for the Table tennis to 39.61 for the rugby, Rugby was one of the greatest maximal calf girth means corrected for the tricep skinfold thickness in all sports (rugby, table tennis, handball, badminton, taekwondo). By scheffe test, rugby was different from badminton. judo different from taekwondo, handball, badminton, table tennis. 5. The muscle mass were ranged from 41.88 for the table tennis to 53.07 for the rugby. Rugby had significantly greater muscle mass than other sports (judo, handball, taekwondo, badminton, table tennis). By scheffe test, rugby was different from taekwondo and judo was different from other sports (handball, taekwondo, badminton, table tennis). 6. The percentage of body mass was ranged from 61.29 for the Judo to 64.34 or the handball. Handball had significantly greater a percentage of body mass than other sports (badminton, taekwondo, rugby, table tennis, judo). By scheffe test, fudo is only different from handball. 7. The sum of skinfold thickness was ranged from 24.9mm for the taekwondo to 36.9mm for the judo. Judo had significantly greater the sum of skinfold thickness than other sports (rugby, badminton, table tennis, handball, taekwondo). By scheffe test, Judo is different from taekwondo and handball.

특징형상개념을 이용한 CNC선반용 CAD/CAM시스템 개발

조진문,김석일,서명원 한국항공대학교 1995 論文集 Vol.33 No.-

Most of CAD/CAM systems for CNC lathe have been developed as the form of automatic programming systems which can generate autormatically or interactively the NC code from the process sheets and design drawings of products. But these systems have some problems during the modeling process of product shap since the shape is not described by the features intimate with system users such as chamfering, rounding, groove, arc and so on. Therfore, in this paer, the feature based CAD/CAM system for CNC lathe which is able to represent the truned product shapes by the typical features, is developed. Especially the system has the various capabilities such as the automatic determination of cutting domains, the automatic generation of CL data and NCcode, the real time cutting simulation for verification of NC code, the DNC operation and so on.

목적있는 운동훈련이 편마비 환자의 좌우 대칭적 서기자세에 미치는 영향

김명진 한국전문물리치료학회 1997 한국전문물리치료학회지 Vol.4 No.1