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강명구 중앙대학교 의과대학 의과학연구소 2009 中央醫大誌 Vol.34 No.1/2
Purpose: We aimed to compare the executive functioning and alcohol relapse risk between alcohol dependent male inpatients with history of familial alcoholism (FHP) and male inpatients without history of familial alcoholism (FHN), and to examine the relationship of the executive function with alcohol relapse risk in alcohol dependent male patients. Methods: The Alcohol Dependence Scale (ADS), the Advance Warning-signs of Relapse Questionnaire (AWARE), Beck Depression Inventory (BDI), Epworth Sleepiness Scale (ESS) and executive function test battery were administered to 31 subjects with alcohol dependence (21: FHP, 10: FHN). The executive function test battery included the controlled oral word association test (COWAT), digit span test (DST), stroop color-word test (SCWT) and similarity test (ST). Results: There were significant differences in the ST scores between FHP and FHN. In all subjects, the DST, ST, COWAT scores were negatively correlated with the AWARE scores. Conclusions: The impairment of executive function of FHP is severer than that of FHN. The executive function of the male alcohol dependent inpatients was associated with the alcohol relapse risk.
이명구 서울보건대학 1995 서울보건대학 부설 한국보건과학연구소 논문집 Vol.1 No.1
Tower cranes are broadly used in the sites constructing high-structure and have a structural sensitiveness. Therefore, accidents have often happened by the deficiency of laborer's understanding and safety of structure. On this study, the cause is investigated for a collapsed tower crane and the counterplans are presented for a prevention of the same disaster in the future. Generally, the accident of tower crane have happened at assembling or disassembling. Therefore, in order to estimate the safety of climbing procedure and device, structure analysis and the sieries of indoor test were carried out. With the random samples gathered in the accident sites, crack investigation test of welded point, chemical component test of members and load test were carried out. And the design of climbing device was scrutinized and the effect of the defect of maintance and control was analyzed. From the result of a sieries of test and analysis, this tower crane was satisfied for the required strength but had become superannuation by the defects of welded points. On the other hand, in order to prevent a collapse by the defect of supporting points, an improvemental idea was presented and an importance of maintenance and control was inspired.
이명구 서울保健大學 1997 論文集 Vol.17 No.1
Damage estimation of bridge structures has recently received considerable attention in the light of maintenance and retrofitting of existing structures under service loads and after natural disasters. A method for the damage assessment of bridge structures using a damage index technique is presented. The damage index is formulated for the changes of modal properties due to the stiffness changes. To verify the method which is presented, numerical analysis and dynamic test are conducted on simple beams. Each simple beam is subjected to different damage scenarios, i. e., locations and degree of damage. Based on the results of this study, it is found that the proposed method is capable of detecting inflicted damages using the eigenvalue of only first mode.
McCoy 세포에서 Chlamydia trachomatis의 병원성 인자에 관한 연구
강정숙,최지영,차영주,김영주,김덕례,여명구,박열 조선대학교 생명과학연구소 1998 생명과학 연구 Vol.6 No.-
본 연구는 병원성 세균인 Chlamydia trachomatis(C. trachomatis)가 숙주세포에침습시 C. trachomatis의 병원성 인자와 C. trachomatis와 상호작용하는 숙주 세포막의 인자를 규명함으로써 숙주세포에 대한 감염율을 향상시켜 보다 향상된 진단 방법을 개발하기 위하여 수행하였다. C. trachomatis로 감염된 세포에서 기본소체의 막 단백질을 분리한 결과 각 혈청형의 39 kDa과 42 kDa에서 major outer membranes(MOMPs)이 관찰되었으며, 혈청형 E와 G의 MOMPs는 42.5 kDa으로 동일하였지만 혈청형 F, H, I, 그리고 K의 MOMPs는 각각 다르게 관찰되었다. C. trachomatis가 숙주세포로 침습시 관련된 병원성 인자에 대하여 조사하고자 단층세포로 배양된 배양용기에 C. trachomatis를 24, 48 그리고 73시간대별로 접종시켜 관찰한 결과 72시간의 MOMPs의 양이 가장 많이 증가하였으며 이 결과로 MOMPS이 C. trachomatis 병원성에 중요한 작용을 함을 확인할 수 있었다. C. trachomatis가 침습시 숙주세포의 막 단백질 변화양상을 관찰하기 위해 정상세포와 C. trachomatis로 1, 2, 3 그리고 4시간대별로 접종 시간을 달리한 숙주세포의 막 단백질을 분리한 결과 42 kDa의 단백질 양이 Chlamydia에 감염된 세포 내에서 증가됨을 관찰할 수 있었다. 이로 42 kDa의 막 단백질이 침습시 숙주세포 표면에 대한 수용체로서 작용함을 알 수 있었다. The present study was performed to analyze the pathogenic factors involved in the invasion process of Chlamydia trachomatis(C. trachomatis) into McCoy cells. In this study, elementary bodies(EBs) of C. trachomatis serotypes(E, F, G, H, I, K and LGV) could be isolated by the method of Percoll density gradient centrifugation and the pathogens of serotypes were also compared from whole-cell lysates by using sodium dodecyl sulfate-polyacrylamide gel elelectrophoresis. All chlamydial serotypes showed a single predominant protein ranging from 39 to 42 kDa. The major outer membrane proteins(MOMPs) of the E and G serotypes had an identical molecular weight of 42.5 kDa. In contrast, the MOMPs of the F, H, I and K serotypes were showed different molecular weights of MOMPs. By immunoblotting with anti-MOMP antibody it was revealed that the quantify of MOMPs was time-dependently increased when McCoy cells were infected with Chlamydia for 24, 48 and 72 hr. These results indicated that MOMPs are closely related to chlamydial infection into the host cell.
Relativistic Radiation Hydrodynamic Equations in Cylindrical Coordinates
Myeong-Gu Park 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.2I
In many astrophysical systems such as accretion disks and jets, radiation interacts with relativistically moving matter. With applications to such systems in mind, I use the covariant tensor conservation laws to derive special relativistic, time-dependent, three-dimensional energy and momentum equations for matter and radiation in cylindrical coordinates. The equations can be conveniently applied to various radiation hydrodynamic processes with cylindrical symmetry. Radiation moments, like the radiation energy density, flux, and pressure, are defined in the comoving (with the flow) frame first and then transformed to the corresponding covariant quantities. The interaction between matter and radiation is also described in the comoving frame while the equations are represented in coordinates that are fixed with respect to the central object. As a concrete example, the relativistic equations of motion for a cylindrical gas flow interacting with a spherically symmetric radiation field are presented.0002