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      • SCIESCOPUS

        Seismic shear strengthening of R/C beams and columns with expanded steel meshes

        Morshed, Reza,Kazemi, Mohammad Taghi Techno-Press 2005 Structural Engineering and Mechanics, An Int'l Jou Vol.21 No.3

        This paper presents results of an experimental study to evaluate a new retrofit technique for strengthening shear deficient short concrete beams and columns. In this technique a mortar jacket reinforced with expanded steel meshes is used for retrofitting. Twelve short reinforced concrete specimens, including eight retrofitted ones, were tested. Six specimens were tested under a constant compressive axial force of 15% of column axial load capacity based on original concrete gross section, $A_g$, and the concrete compressive strength, ${f_c}^{\prime}$. Main variables were the spacing of ties in original specimens and the volume fraction of expanded metal in jackets. Original specimens failed before reaching their nominal calculated flexural strength, $M_n$, and had very poor ductility. Strengthened specimens reached their nominal flexural strength and had a ductility capacity factor of up to 8 for the beams and up to 5.5 for the columns. Based on the test results, it can be concluded that expanded steel meshes can be used effectively to strengthen shear deficient concrete members.

      • KCI등재

        Culture Conditions for In Vitro Maturation of Abattoir Derived Oocytes of Native Zebu Cows of Bangladesh

        Morshed, S.M. Niyaz,Bhuiyan, Mohammad Musharraf Uddin,Rahman, Mohammad Moshiur,Singha, Joydev Kumer,Juyena, Nasrin Sultana The Korean Society of Embryo Transfer 2014 한국동물생명공학회지 Vol.29 No.3

        The objectives of the study were to determine an effective culture dish, culture duration and protein supplementation in medium for in vitro maturation (IVM) of oocytes of native zebu cows in Bangladesh. The ovaries of cows were collected from local slaughterhouse followed by aspiration of follicular fluid. The cumulus-oocyte-complexes (COCs) with more than 3 compact cumulus cell layers were cultured in tissue culture medium (TCM) 199 for maturation. The maturation of oocytes was determined by observing polar body under microscope. To determine an effective culture dish, 130 COCs derived from 48 ovaries in a well of 4-well dish and 102 COCs derived from 36 ovaries in drops covered with mineral oil within 35 mm petri dish were cultured for 24 hours. The rate of maturation of oocytes did not vary between 4-well dish ($51.3{\pm}15.0%$) and drops in petri dish ($52.4{\pm}11.6%$). To determine the effective culture duration, 185 COCs derived from 62 ovaries were cultured in drops for 18, 21, 24 and 27 hours. The rate of maturation of occytes ranged from $51.9{\pm}9.4%$ (18 hours) to $59.0{\pm}17.1%$ (27 hours) and the difference in maturation rate among different culture durations was not significant (P>0.05). To determine an effective protein supplementation, 63 oocytes from 19 ovaries were cultured separately in TCM 199 supplemented with either fetal bovine serum (FBS) or bovine serum albumin (BSA). The rate of maturation was significantly (P<0.01) higher in medium supplemented with FBS ($55.63{\pm}16.19%$) than that of BSA ($14.82{\pm}9.36%$). In conclusion, COCs of native zebu cows can be cultured for IVM either in 4-well culture dish or droplets in petri dish for 18 to 27 hours in medium supplemented with FBS.

      • KCI등재후보

        Bayesian Conway-Maxwell-Poisson (CMP) regression for longitudinal count data

        Morshed Alam,Yeongjin Gwon,Jane Meza The Korean Statistical Society 2023 Communications for statistical applications and me Vol.30 No.3

        Longitudinal count data has been widely collected in biomedical research, public health, and clinical trials. These repeated measurements over time on the same subjects need to account for an appropriate dependency. The Poisson regression model is the first choice to model the expected count of interest, however, this may not be an appropriate when data exhibit over-dispersion or under-dispersion. Recently, Conway-Maxwell-Poisson (CMP) distribution is popularly used as the distribution offers a flexibility to capture a wide range of dispersion in the data. In this article, we propose a Bayesian CMP regression model to accommodate over and under-dispersion in modeling longitudinal count data. Specifically, we develop a regression model with random intercept and slope to capture subject heterogeneity and estimate covariate effects to be different across subjects. We implement a Bayesian computation via Hamiltonian MCMC (HMCMC) algorithm for posterior sampling. We then compute Bayesian model assessment measures for model comparison. Simulation studies are conducted to assess the accuracy and effectiveness of our methodology. The usefulness of the proposed methodology is demonstrated by a well-known example of epilepsy data.

      • KCI등재

        Atomic boundary position and steric effects on ion transport and separation through nanoporous graphene membrane

        Morshed Mahmud,김보흥 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.2

        The electrostatic attraction between ions and water is the primary reason for the change in ion bare diameter, which plays a crucial role in saltwater transportation. This study utilizes molecular dynamics (MD) to analyze saltwater transport through a nanoporous graphene membrane by pressure-driven flow. In this work, we describe the impact of pore diameter atomic boundary position on single-ion transportation and signify the steric effect of ions on the water mass flow rate and velocity profile. Due to hydration layer formation, ions hinder the water molecules from their regular velocity, which also decreases the flow rate of water molecules. Interestingly, a significant deviation for different atomic boundary positions is observed for ion rejection for pore diameters less than 1 nm. However, for larger pore diameters, the ion rejection closely matches the atomic boundary position specified by a 2 % water density drop inside the nanopore.

      • SCOPUSKCI등재
      • Approaching Hydration Boundary on Ion Transport and Separation through Nanoporous Graphene Membrane

        Morshed Mahmud,BoHung Kim 대한기계학회 2021 대한기계학회 춘추학술대회 Vol.2021 No.6

        Due to the polarization of water molecules, the hydration sphere around a single ion increases the effective size of the ion. This phenomenon is called a steric effect that plays a key role in ion transport and separation through a nanopore. Using molecular dynamics (MD) simulation, this transport mechanism of ions through a nanoporous graphene membrane (NPGM) has been analyzed. To induce the water flowrate and ion transport, a pressure-driven flow is generated using specular reflection wall movement at a constant speed for both reservoirs. MD simulations were performed for four different pore sizes to see the scale effect on ion transport. It was observed that ion transportation is proportional to the pore boundary increment due to the shifting of the hydration boundary around a single ion. To investigate this incident, we defined different boundary positions of the hydration layer around a single ion based on the ion water distance. Since the ion transport and separation through the nanopore is very sensitive to the small change in pore diameter, t he exact boundary of pore diameter also needs to be defined. In this consequence, we defined different pore boundaries and predicted the approximate pore boundary of the nanopore based on the Sampson flow equation as a comparison with MD measured data. In the end, after compared with the approximate pore boundary, we establish a maximum hydration boundary of ion that approaches the nanopore concerning the hydration energy in each layer.

      • Association between Angiotensin I-Converting Enzyme Gene Polymorphism and Hypertension in Selected Individuals of the Bangladeshi Population

        Morshed, Mahboob,Khan, Haseena,Akhteruzzaman, Sharif 생화학분자생물학회 2002 Journal of biochemistry and molecular biology Vol.35 No.3

        The genetic factors that contribute to the development of coronary artery disease (CAD) are poorly understood. It is likely that multiple genes that act independently or synergistically contribute to the development of CAD and the outcome. Recently, an insertion/deletion (I/D) polymorphism of the human angiotensin I-converting enzyme (ACE) gene, a major component of the renin-angiotensin system (RAS), was identified. The association of the ACE gene D allele with essential hypertension and CAD has been reported in the African-American, Chinese, and Japanese populations. However, other studies have failed to detect such an association. It has been suggested that these inconsistencies may be due to the difference in backgrounds of the population characteristics. In the present study, we investigated the I/D polymorphism of the ACE gene in 103 subjects of both sexes, consisting of 59 normal controls and 44 patients with hypertension. The allele and genotype frequency were significantly different between the hypertensive and control groups (p < 0.01). Among the three ACE I/D variants, the DD genotype was associated with the highest value of the mean systolic blood pressure [SBP] and mean diastolic blood pressure [DBP] (p = < 0.05) in men, but not in women. In the overall population, the mean SBP and DBP was highest in DD subjects, intermediate in I/D subjects, and the least in II subjects.

      • KCI등재

        Application of remote sensing for salinity based coastal land use zoning in Bangladesh

        Morshed Md. Manjur,Sarkar Showmitra Kumar,Zzaman Md. Rashed Uz,Islam Md. Mazharul 대한공간정보학회 2021 Spatial Information Research Vol.29 No.3

        Rising soil and water salinity is a major concern for coastal areas. Salt-water shrimp aquaculture is a land use mal-adaption to the rising salinity trend, and is contributing to the salinity expansion as well as lowering land productivity in the coastal areas of Bangladesh. This paper aims to propose a salinity-based land use zoning to restrict salinity expansion and to reduce land use conflicts. An integrated salinity detection technique combing field soil samples, a geographic information system and remote sensing were used. Subsequently, two determining factors of land suitability—soil salinity and distance from saline water sources—were used to identify zones for paddy/crop, mixed use and shrimp. The study districts witnessed rising salinity between 1990 and 2016, and thereby, decreasing suitable land are for paddy/crop by 20.96% of the agricultural area. The land suitability for paddy, mixed use and shrimp zones was found to be 51.88%, 29.36% and 18.76% of the study area, respectively. The proposed zoning strategy of this paper can be used as a quick and efficient tool for baseline information for integrated coastal zone management plan.

      • Pharmacophore Identification and Validation Study of CK2 Inhibitors Using CoMFA/CoMSIA

        Morshed, Mohammad Neaz,Muddassar, Muhammad,Pasha, Farhan Ahmad,Cho, Seung Joo Blackwell Publishing Ltd 2009 Chemical biology & drug design Vol.74 No.2

        <P>Protein kinase CK2, also known as casein kinase-2, has been found to be involved in cell growth, proliferation and suppression of apoptosis, which is related to human cancers. The series of compounds were identified as casein kinase-2 inhibitors and their inhibitory activities are a function of a variation of their structures. The current study deals with the pharmacophore identification and, accordingly, the three-dimensional quantitative structure–activity relationship model development using Pharmacophore Alignment and Scoring Engine. Several hypotheses were developed for the molecular alignments. On the basis of statistical values, the best-fitted model was identified and the same alignment was used for 3D-QSAR using comparative molecular field analysis/comparative molecular similarity index analysis. Both the CoMFA (<I>R</I> <SUP>2</SUP><SUB>CV</SUB><I> </I>= 0.58, <I>R</I> <SUP>2</SUP> = 0.82 and <I>r</I> <SUP>2</SUP><SUB>pred</SUB> = 0.62) and the comparative molecular similarity index analysis (<I>R</I> <SUP>2</SUP><SUB>CV</SUB> = 0.74, <I>R</I> <SUP>2</SUP><I> </I>= 0.98 and <I>r</I> <SUP>2</SUP><SUB>pred</SUB> = 0.81) gave reasonable results. Besides pharmacophore-based alignment, the maximum common substructure-based alignment was also used for the comparative molecular field analysis and comparative molecular similarity index analysis. The pharmacophore-based alignment was more prominent and it has provided important information for the modelling of potent inhibitors. The overall study implies that a highly positive and bulky group with H-bond donating property is desirable around the nitrogen atom adjacent to the pyrrolidine ring.</P>

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