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Morgana Camacho,Karl J. Reinhard 대한기생충학열대의학회 2019 The Korean Journal of Parasitology Vol.57 No.6
There is often the risk of confusing pollen grains with helminth eggs from archaeological sites. Thousands to millions of pollen grains can be recovered from archaeological burial sediments that represent past ritual, medication and environment. Some pollen grain types can be similar to parasite eggs. Such a confusion is represented by the diagnosis of enterobiasis in ancient Iran. The authors of this study confused a joint-pine (Ephedra spp.) pollen grain with a pinworm egg. This paper describes the specific Ephedra pollen morphology that can be confused with pinworm eggs.
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Andiara E. Freitas,Morgana Moretti,Josiane Budni,,Grasiela O. Balen,Sinara C. Fernandes,Patricia O. Veronezi,Melina Heller,Gustavo A. Micke,Moacir G. Pizzolatti,Ana Lu´cia S. Rodrigues 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.11
Bark infusion of Tabebuia avellanedae Lorentz ex Griseb is consumed in tropical America folk medicine for the treatment of several diseases, including depressive disorders. It was recently demonstrated that the extract from this plant has antidepressant properties. The present study was aimed at investigating the contribution of N-methyl-D-aspartate (NMDA) receptors and the L-arginine–nitric oxide (NO)–cyclic guanosine 3050-monophosphate (cGMP) pathway to the antidepressantlike action of the ethanolic extract from T. avellanedae (EET) in the tail suspension test (TST). The anti-immobility effect of the extract (30 mg/kg, orally [p.o.]) was prevented by pretreatment of mice with NMDA (0.1 pmol/site, intracerebroventicular [i.c.v.]), L-arginine (750 mg/kg, intraperitoneally [i.p.]), and sildenafil (5 mg/kg, i.p.). Additionally, the combination of MK-801 (0.01 mg/kg, p.o.), 7-nitroindazole (25 mg/kg, i.p.), and 1H-[1,2,4]oxadiazole[4,3-a]quinoxalin-1-one (ODQ) (30 pmol/site, i.c.v.) with a subeffective dose of EET (1 mg/kg, p.o.) produced a synergistic antidepressant-like effect in the TST, without causing significant alterations in the locomotor activity. Moreover, the administration of an effective dose of EET (30 mg/kg, p.o.) produced a reduction in NOx levels in the cerebral cortex. Conversely, a subeffective dose of EET (1 mg/kg, p.o.) caused no changes in the cortical NOx levels. Results suggest that the antidepressant-like effect of EET in the TST is dependent on a blockade of NMDA receptor activation and inhibition of NO-cGMP synthesis, significantly extending literature data about the antidepressant-like action of this plant and reinforcing the notion that this plant may be useful in the management of depressive disorders.
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Pinworm Infection at Salmon Ruins and Aztec Ruins: Relation to Pueblo III Regional Violence
Karl J Reinhard,Morgana Camacho 대한기생충학열대의학회 2019 The Korean Journal of Parasitology Vol.57 No.6
The study of coprolites has been a theme of archaeology in the American Southwest. A feature of archaeoparasitology on the Colorado Plateau is the ubiquity of pinworm infection. As a crowd parasite, this ubiquity signals varying concentrations of populations. Our recent analysis of coprolite deposits from 2 sites revealed the highest prevalence of infection ever recorded for the region. For Salmon Ruins, the deposits date from AD 1140 to 1280. For Aztec Ruins, the samples can be dated by artifact association between AD 1182-1253. Both sites can be placed in the Ancestral Pueblo III occupation (AD 1100-1300), which included a period of cultural stress associated with warfare. Although neither of these sites show evidence of warfare, they are typical of large, defensible towns that survived this time of threat by virtue of large populations in stonewalled villages with easily accessible water. We hypothesize that the concentration of large numbers of people promoted pinworm infection and, therefore, explains the phenomenal levels of infection at these sites.
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Karina Laurenti Sato,Luciana Sayuri Sanada,Morgana Duarte da Silva,Rodrigo Okubo,Kathleen A. Sluka 대한통증학회 2020 The Korean Journal of Pain Vol.33 No.2
Background: Transcutaneous electrical nerve stimulation (TENS), manual acupuncture (MA), and spinal cord stimulation (SCS) are used to treat a variety of pain conditions. These non-pharmacological treatments are often thought to work through similar mechanisms, and thus should have similar effects for different types of pain. However, it is unclear if each of these treatments work equally well on each type of pain condition. The purpose of this study was to compared the effects of TENS, MA, and SCS on neuropathic, inflammatory, and non-inflammatory pain models. Methods: TENS 60 Hz, 200 μs, 90% motor threshold (MT), SCS was applied at 60 Hz, an intensity of 90% MT, and a 0.25 ms pulse width. MA was performed by inserting a stainless-steel needle to a depth of about 4-5 mm at the Sanyinjiao (SP6) and Zusanli (ST36) acupoints on a spared nerve injury (SNI), knee joint inflammation (3% carrageenan), and non-inflammatory muscle pain (intramuscular pH 4.0 injections) in rats. Mechanical withdrawal thresholds of the paw, muscle, and/or joint were assessed before and after induction of the pain model, and daily before and after treatment. Results: The reduced withdrawal thresholds were significantly reversed by application of either TENS or SCS (P < 0.05). MA, on the other hand, increased the withdrawal threshold in animals with SNI and joint inflammation, but not chronic muscle pain. Conclusions: TENS and SCS produce similar effects in neuropathic, inflammatory and non-inflammatory muscle pain models while MA is only effective in inflammatory and neuropathic pain models.
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The Use of Cryotherapy in the Gout Pain Control: A Systematic Review
Alana Ludemila de Freitas Tavares,Iranilda Moha Ross,Lilian Araujo Pradal,Morgana Neves,Bárbara Heloise Trombetta Jamilk,Gladson Ricardo Flor Bertolini KEMA학회 2021 근골격계과학기술학회 Vol.5 No.1
Background Gout traditional treatment consists of anti-inflammatory drugs, analgesics and other rheumatic controllers, however, the occurrence of drug interactions occurs with a certain degree of toxicity, requiring that other methods be used to relieve symptoms. An alternative treatment is cryotherapy due to its capacity for analgesia. Purpose The aim of this study was to conduct a systematic review that addressed the literature with production on gouty arthritis and its treatment with cryotherapy. Study design Systematic review Methods This review was described according to the items requested by the PRISMA system. This is a systematic review of publications from the year 2000 to the year 2019 in the following white literature databases PubMed, LILACS, SciELO, Web of Science, Science Direct, Scopus, Cochrane, PEDro and in the gray literature a Google Scholar database. The electronic databases were consulted from November 2019. Results After searching the databases, reading and selection, two studies contemplated the methodological criteria of eligibility, being of the same authorship, both with more than ten years of publication, using similar methods of application of ice. Conclusions It was found that, despite the scarcity of studies that addressed the topic, the articles found show reasonable rigor methodological and homogeneous results, demonstrating that cryotherapy helps in reducing the pain of individuals with gout, however, there is little evidence to support this hypothesis.
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