http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Regional Distribution of Hepatitis C Virus Infection in the Republic of Korea, 2007-2011
( Geun Yong Kwon ),( Hyung Min Lee ),( Jin Gwack ),( Sang Won Lee ),( Moran Ki ),( Seung Ki Youn ) 대한소화기학회 2014 Gut and Liver Vol.8 No.4
Background/Aims: In Korea, hepatitis C is included as an infectious disease in a sentinel surveillance system. Recently, a large variation in hepatitis C incidence between different regions in Korea has been noticed. The current study verified the nationwide distribution of hepatitis C infection for effective prevention and management. Methods: We counted the number of hepatitis C patients who visited a hospital per county using the National Health Insurance database from 2007 to 2011. The age-adjusted prevalence ratio was used, and the age adjustment method was used as an indirect standardization method. Disease mapping and spatial analysis were conducted using a geographic information system. Results: The annual prevalence of diagnosed hepatitis C was approximately 0.12% to 0.13% in Korea. The age-adjusted prevalence ratios in Busan, Jeonnam, and Gyeongnam were high (1.75, 1.4, and 1.3, respectively). The three regions in the southern coastal area of the Korean Peninsula were identified as a high-prevalence cluster (Moran`s index, 0.3636). Conclusions: The present study showed that hepatitis C infection has very large regional variation, and there are several high-risk areas. Preventive measures focusing on these areas should be applied to block the transmission of hepatitis C and reduce the disease burden. (Gut Liver 2014;8:428-432)
Risk of Hepatocellular Carcinoma in Korean Patients with Metabolic Syndrome: A Big Data Analysis
( Moran Ki ),( Hwa Young Choi ),( Bo Hyun Kim ),( Joong-won Park ) 대한간학회 2016 춘·추계 학술대회 (KASL) Vol.2016 No.1
Aims: The Metabolic syndrome (MetS) and/or its individual componentshave been linked to the development of various cancers. Recentstudies have suggested MetS as a risk factor of hepatocellular carcinoma(HCC). However, the association between MetS and HCC is incontroversial especially in an HBV- and HCV-endemic area. We evaluatedthe association between the MetS and HCC in Korea.Methods: The HCC incidences according to the MetS were analyzedin general population by using the Health Examination Cohort dataof National Health Insurance. We followed all 112,794 people whowere 40-79 years old and had health examination in 2002 or 2003.According to limited source justification, the criteria for MetS areas follows: BMI 25+, hypertension SBP 130+ or DBP 85+, fastingblood glucose (FBG) 100mg/dL+ and total cholesterol (TC) 240mg/dL+. Cox proportional hazard regression models were used.Results: Out of 112,794 people, 40,443(35.9%) had one,26,410(23.4%) had two, 19,874(17.6%) had three, and 1,604(1.4%)had four components of MetS. HCC incidence rates for 10 yearswere 1.27% for one, 1.38% for two, 0.59% for three, and 1.12%for four components groups of MetS. Univariate analysis on risk ofHCC showed significant results with hypertension (HR: 1.184), FBG(HR: 1.256) and TC (HR: 0.676). However, after adjusting for age,sex, alcohol drinking, and viral hepatitis (B and/or C), only TC (HR:0.717) showed a significant result. After excluding TC which showedprotective effect, adjusted HRs of BMI, FBG, and hypertension werenot significant (1.016, 1.046 and 1.038, respectively).Conclusions: MetS may not be a significant risk for HCC developmentin a Korean population-based study. A subsequent analysis of theHCC risk and MetS is currently under way in the second set includingdata of triglyceride and HDL-cholesterol.
Moran Ki 한국역학회 2020 Epidemiology and Health Vol.42 No.-
In about 20 days since the diagnosis of the first case of the 2019 novel coronavirus (2019-nCoV) in Korea on January 20, 2020, 28 cases have been confirmed. Fifteen patients (53.6%) of them were male and median age of was 42 years (range, 20-73). Of the confirmed cases, 16, 9, and 3 were index (57.2%), first-generation (32.1%), and second-generation (10.7%) cases, respectively. All first-generation and second-generation patients were family members or intimate acquaintances of the index cases with close contacts. Fifteen among 16 index patients had entered Korea from January 19 to 24, 2020 while 1 patient had entered Korea on January 31, 2020. The average incubation period was 3.9 days (median, 3.0), and the reproduction number was estimated as 0.48. Three of the confirmed patients were asymptomatic when they were diagnosed. Epidemiological indicators will be revised with the availability of additional data in the future. Sharing epidemiological information among researchers worldwide is essential for efficient preparation and response in tackling this new infectious disease.
Moran, John B. Asian Australasian Association of Animal Productio 2009 Animal Bioscience Vol.22 No.12
This review presents a series of Key Performance Indicators (KPI) to assist Asian smallholder dairy farmers in identifying the possible causes for their poor farm performance and profitability. When assessing farm profitability, these indicators can be split into two types, those diagnosing problems with feeding management and those indicating poor herd management. As home grown forage is generally cheaper to source than purchased forage, the more produced on farm, the better. Too many stock on limited land is a common feature on Asian dairy small holdings. Unlike other classes of livestock, milking cows have very high nutrient requirements, therefore high quality forages and concentrates are essential for profitable dairying. Milk income less feed cost is one of the simplest and easy to measure indicators of farm profitability and is also quick to respond to small changes in farm practices. Problems with herd management can be diagnosed using measures such as the proportion of cows actually milking in the herd or their peak yield and persistency of production. There are also simple indicators of herd reproductive performance and of health and growth of young stock that assist in searching for the underlying causes of poor farm profitability.
Causes and countermeasures for repeated outbreaks of hepatitis A among adults in Korea
Moran Ki,Hyunjin Son,Bo Youl Choi 한국역학회 2019 Epidemiology and Health Vol.41 No.-
The 2019 hepatitis A outbreak has become increasingly prevalent among adults in Korea and is the largest outbreak since that in 2009-2010. The incidence in the current outbreak is highest among adults aged 35-44 years, corresponding to the peak incidence among those aged 25-34 years 10 years ago. This may indicate a cohort effect in the corresponding age group. Causes of these repeated outbreaks of hepatitis A in Korea are low level of immunity among adults, Korean food culture that consumes raw seafood such as salted clam and inadequate public health system. Among countermeasures, along with general infectious disease control measures including control of the infectious agent, infection spread, and host, urgent actions are needed to review the vaccination policy and establish an adequate public health system.