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Interaction between body mass index (BMI) and dyslipidemia
Jin Mok Kim,Mi Hyeon Jin,Choung Gun Kim,Dawon Kang,Jae-Hyeon Cho 한국예방수의학회 2024 예방수의학회지 Vol.48 No.1
This study examined the relationship between Body mass index (BMI) classification and the occurrence of dyslipidemia using 3 years of health examination data from a university hospital in Changwon, and seeked to find other factors that affect dyslipidemia. Multivariate logistic regression analysis investigated the most common risk factors for developing dyslipidemia and used Kaplan-Meier survival curves to predict the probability of developing dyslipidemia according to BMI class. We then analyzed the effects of metabolic indicators such as smoking habits, alcohol consumption, blood pressure, glucose, hemoglobin A1c (HbA1c), and insulin. The Type I error rate was controlled through Bonferroni correction for multiple comparisons to extract reliable statistical data. in the present study, these results showed that the probability of developing dyslipidemia was high in the obese group, and confirmed that lifestyle habits such as smoking and drinking were highly correlated with the occurrence of dyslipidemia. Therefore, we suggest that dyslipidemia management and prevention strategies require public health policies that comprehensively manage lifestyle factors such as gender and weight management, smoking cessation, and drinking habits.
하현목 ( Hyeon Mok Ha ) 인도철학회 2014 印度哲學 Vol.0 No.42
나가르주나가 自性(svabhava)의 空性(sunyata)을 천명한 이후, 자성과 의존은 인도 철학에서 주요 논제 가운데 하나가 되었다. 유자성론자들과 중관학파는 이 주제에 대해 오랜 기간 논쟁을 해 왔다. 핵심 쟁점은 자성과 의존의 개념을 존재론적으로 어떻게 설명하는가이다. 이에 관해 먼저 유자성론자들은 자성을 만들어지거나 다른 것에 의존하지 않는 것으로 파악한다. 그들은 자성이 실재한다고 주장한다. 유자성론자들은 存在(sattva)와 非存在(asattva), 有法(dharmin)과 法 (dharma)이 모두 자성을 가지고 실재한다고 주장한다. 또한 그들은 자성을 가지고 있는 존재들이 상호 의존하는 것으로 이해한다. 반면에 중관학파는 유자성론자들이 주장하는 자성이 실재하지 않는다고 비판한다. 이 학파에서는 존재와 비존재, 유법과 법이 각각 상호 의존하여 존재하는 것이므로 無自性(nihsvabhava) 이라고 말한다. 또한 중관학파는 존재와 비존재의 관계를 개념적 의존으로 파악하고, 유법과 법의 관계를 존재론적 의존으로 파악한다. Ever since Nagarjuna, the founder of the Buddhist Madhyamaka school, made clear that intrinsic nature (svabhava) is empty (sunya), svabhava and dependence had became one of the main theses in Indian religious philosophy. Philosophers who believe that svabhava is real and Madhyamaka school took a long debate on this subject. One of the points at issue is how to explicate the concepts of svabhava and dependence in ontological dimension. Philosophers who believe that svabhava is real accepted svabhava as the thing which does not depend on cause (hetu) and condition (pratyaya). They also claims that svabhava is real. In their view, existence, nonexistence, dharmin and dharma are regarded as substantial existence. They also grasped existences having svabhava as interdependent relationship. The Madhyamaka philosophers, on the other hand, deny theview that svabhava is real. This is based on the Buddha`s theory of dependent origination (prati.tyasamutpa.da). This philosophical system claims that existence, nonexistence, dharmin, and dharma have no svabhava because they are existent by mutual dependence. This philosophical system also grasps the relation between existence and nonexistence as conceptual dependence, and the relation between dharmin and dharma as ontological dependence.
A novel approch of usage of Gram staining to indentify Mycobacterium tuberculosis from tissues
Jin Mok Kim(Jin Mok Kim),Ji Eun Oh(Ji Eun Oh),Reye Kim(Reye Kim),Yeong-Jin Heo(Yeong-Jin Heo),Jae-Hyeon Cho(Jae-Hyeon Cho) 한국예방수의학회 2023 예방수의학회지 Vol.47 No.1
Tuberculosis is a potentially deadly infectious disease caused by the Mycobacterium tuberculosis (M. tuberculosis). Tuberculosis is diagnosed by proving the M. tuberculosis in sputum samples based on the results of acid-resistant staining, culture, and nucleic acid amplification tests. However, there is a report that the detection rate of M. tuberculosis is low in acid-resistant staining using tissue specimens. It has been suspected that the cause is a potential loss of acid resistance by the organic solvents used for tissue specimen preparation. Therefore, this study was pursued to find out if Gram staining and fluorescent staining in addition to acid-resistant staining would be helpful in diagnosing tuberculosis. We used four tissue (lung, small intestine, large intestine, and lymph node) samples with chronic granulomatous inflammation observed in HE staining and positive results in real-time PCR. These detection rates and staining properties were investigated through microscopic examination using the Ziehl-Neelsen, Gram, and Auramin rhodamine staining. In this studies, M. tuberculosis were observed by Ziehl-Neelsen, Gram, and Auramin rhodamine staining in all four samples. In the evaluation of clinical microbiology proficiency testing (CMPT), the Ziehl-Neelsen and Gram staining were the same result, but the Auramin rhodamine staining was relatively low. These data indicated that Gram staining is useful for detecting M. tuberculosis in formalin-fixed tissue specimens. Therefore, if the Ziehl-Neelsen and Gram staining are combined as the M. tuberculosis staining method in tissue specimens, a better direction may be provided for tuberculosis diagnosis.
Echinostoma ilocanum Infection in Oddar Meanchey Province, Cambodia
Woon-Mok Sohn,Hyeong-Jin Kim,Tai-Soon Yong,Keeseon S. Eom,Hoo-Gn Jeong,Jae-Kwang Kim,A-Reum Kang,Mok-Ryun Kim,Jung-Mi Park,Soo-Hyeon Ji,Muth Sinuon,Duong Socheat,Jong-Yil Chai 대한기생충학열대의학회 2011 The Korean Journal of Parasitology Vol.49 No.2
Fecal examinations using the Kato Katz technique were performed on a total of 1,287 villagers (945 students and 342 general inhabitants) of Oddar Meanchey Province, Cambodia in May 2007 and November 2009. The overall intestinal helminth egg positive rate was 23.9%, and the most prevalent helminth species was hookworms (21.6%). Other helminth eggs detected included echinostomes (1.0%), Enterobius vermicularis (0.8%), small trematode eggs (0.7%), which may include Opisthorchis viverrini and Haplorchis spp., and Hymenolepis nana (0.4%). In order to recover adult echinostomes, we treated 2 patients with 10-15 mg/kg praziquantel and purged. Total 14 adult echinostomes, 1 and 13 worms from each patient, were collected. The echinostomes characteristically had 49-51 collar spines and 2 round or slightly lobated testes. They were identified as Echinostoma ilocanum (Garrison, 1908) Odhner, 1911. So far as literature are concerned, this is the first record on the discovery of human E. ilocanum infection in Cambodia.
목동현(Dong Hyeon Mok),이우석(WooSeok Lee),김종승(JongSeung Kim),정현동(Hyun Dong Jung),장호연(Ho Yeon Jang),문성진(SungJin Moon),이채연(ChaeHyeon Lee),백서인(Seoin Back) 한국세라믹학회 2022 세라미스트 Vol.25 No.2
Towards a sustainable energy future, it is essential to develop new catalysts with improved properties for key catalytic systems such as Haber-Bosch process, water electrolysis and fuel cell. Unfortunately, the current state-of-the-art catalysts still suffer from high cost of noble metals, insufficient catalytic activity and long-term stability. Furthermore, the current strategy to develop new catalysts relies on “trial-and-error” method, which could be time-consuming and inefficient. To tackle this challenge, atomic-level simulations have demonstrated the potential to facilitate catalyst discovery. For the past decades, the simulations have become reasonably accurate so that they can provide useful insights toward the origin of experimentally observed improvements in catalytic properties. In addition, with the exponential increase in computing power, high-throughput catalyst screening has become feasible. More excitingly, recent advances in machine learning have opened the possibility to further accelerate catalyst discovery. Herein, we introduce recent applications and challenges of computation and machine learning for catalyst discovery.
Bak, So Hyeon,Kim, Sung Mok,Park, Sung-Ji,Kim, Min-Ji,Choe, Yeon Hyeon Korean Society of Magnetic Resonance in Medicine 2017 Investigative Magnetic Resonance Imaging Vol.21 No.1
Purpose: To evaluate quantification results of single breath-hold (SBH) magnetic resonance (MR) cine imaging compared to results of conventional multiple breath-hold (MBH) technique for left ventricular (LV) function in patients with cardiac arrhythmia. Materials and Methods: MR images of patients with arrhythmia who underwent MBH and SBH cine imaging at the same time on a 1.5T MR scanner were retrospectively reviewed. Both SBH and MBH cine imaging were performed with balanced steady state free precession. SBH scans were acquired using temporal parallel acquisition technique (TPAT). Fifty patients ($65.4{\pm}12.3years$, 72% men) were included. End-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), ejection fraction (EF), myocardial mass, and LV regional wall motion were evaluated. Results: EF, myocardial mass, and regional wall motion were not significantly different between SBH and MBH acquisition techniques (all P-values > 0.05). EDV, ESV, and SV were significant difference between the two techniques. These parameters for SBH cine imaging with TPAT tended to lower than those in MBH. EF and myocardial mass of SBH cine imaging with TPAT showed good correlation with values of MBH cine imaging in Passing-Bablok regression charts and Bland-Altman plots. However, SBH imaging required significantly shorter acquisition time than MBH cine imaging ($15{\pm}7sec$ vs. $293{\pm}104sec$, P < 0.001). Conclusion: SBH cine imaging with TPAT permits shorter acquisition time with assessment results of global and regional LV function comparable to those with MBH cine imaging in patients with arrhythmia.