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Global patterns of hepatocellular carcinoma management from diagnosis to death: the BRIDGE Study
Park, Joong-Won,Chen, Minshan,Colombo, Massimo,Roberts, Lewis R,Schwartz, Myron,Chen, Pei-Jer,Kudo, Masatoshi,Johnson, Philip,Wagner, Samuel,Orsini, Lucinda S,Sherman, Morris Wiley-Blackwell Publishing 2015 Liver International Vol.35 No.9
<P><B>Background & Aims</B></P><P>Hepatocellular carcinoma (HCC) is the second most common cause of cancer deaths worldwide. The global HCC BRIDGE study was a multiregional, large-scale, longitudinal cohort study undertaken to improve understanding of real-life management of patients with HCC, from diagnosis to death.</P><P><B>Methods</B></P><P>Data were collected retrospectively from January 2005 to September 2012 by chart reviews of eligible patients newly diagnosed with HCC at participating institutions.</P><P><B>Results</B></P><P>Forty-two sites in 14 countries contributed final data for 18 031 patients. Asia accounted for 67% of patients, Europe for 20% and North America for 13%. As expected, the most common risk factor was hepatitis C virus in North America, Europe and Japan, and hepatitis B virus in China, South Korea and Taiwan. The most common Barcelona Clinic Liver Cancer stage at diagnosis was C in North America, Europe, China and South Korea, and A in Taiwan and Japan. Across all stages, first HCC treatment was most frequently transarterial chemoembolization in North America, Europe, China and South Korea, percutaneous ethanol injection or radiofrequency ablation in Japan and resection in Taiwan. Survival from first HCC treatment varied significantly by region, with median overall survival not reached for Taiwan and 60, 33, 31, 24 and 23 months for Japan, North America, South Korea, Europe and China respectively (<I>P</I> < 0.0001).</P><P><B>Conclusions</B></P><P>Initial results from the BRIDGE study confirm previously reported regional trends in patient demographic characteristics and HCC risk factors, document the heterogeneity of treatment approaches across regions/countries and underscore the need for earlier HCC diagnosis worldwide.</P>
Ziyang Lu,Zehui Yu,Minshan Song,XINLIN LIU,Yang Liu,Yongsheng Yan,Pengwei Huo,Hongjun Dong,Fei Chen,Song Han 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.1
A novel functional inorganic imprinted ZnFe2O4@Ag3PO4/SiO2 photocatalyst was synthesized by a facile sol–gel method combined with the surface imprinting technique, which possessed excellent stability. By optimizing the amount of materials, we determine the preferable addition amounts of tetraethoxysilane (TEOS) and tetracycline to be 0.06 mL and 0.06 g, respectively. This as-prepared functional inorganic imprinted ZnFe2O4@Ag3PO4/SiO2 photocatalyst was proved to not only exhibit high photocatalytic activity (the photodegradation rate was 61.52% under the simulated sunlight irradiation of 60 min), but also possess a strong oriented ability to selectively recognize and photocatalyze tetracycline (the coeficient of selectivity (k selectivity) was 5.14 for ciprofloxacin and 3.63 for gatifloxacin). Moreover, the functional inorganic imprinted ZnFe2O4@Ag3PO4/SiO2 photocatalyst prepared with SiO2 as the inorganic imprinted layer has good stability and can be recycled many times. This work not only puts forward a novel design idea of functional semiconductor materials but also is expected to be widely applied to the oriented catalysis for a target substance according to the practical requirement.
Research and practice of health monitoring for long-span bridges in the mainland of China
Li, Hui,Ou, Jinping,Zhang, Xigang,Pei, Minshan,Li, Na Techno-Press 2015 Smart Structures and Systems, An International Jou Vol.15 No.3
The large number of long-span bridges constructed in China motivates the applications of structural health monitoring (SHM) technology. Many bridges have been equipped with sophisticated SHM systems in the mainland of China and in Hong Kong of China. Recently, SHM technology has been extended to field test systems. In this view, SHM can serve as a tool to develop the methods of life-cycle performance design, evaluation, maintenance and management of bridges; to develop new structural analysis methods through validation and feedback from SHM results; and to understand the behavior of bridges under natural and man-made disasters, rapidly assess the damage and loss of structures over large regions after disasters, e.g., earthquake, typhoon, flood, etc. It is hoped that combining analytical methods, numerical simulation, small-scale tests and accelerated durability tests with SHM could become the main engine driving the development of bridge engineering. This paper demonstrates the above viewpoint.
Research and practice of health monitoring for long-span bridges in the mainland of China
Hui Li,Jinping Ou,Xigang Zhang,Minshan Pei,Na Li 국제구조공학회 2015 Smart Structures and Systems, An International Jou Vol.15 No.3
The large number of long-span bridges constructed in China motivates the applications ofstructural health monitoring (SHM) technology. Many bridges have been equipped with sophisticated SHMsystems in the mainland of China and in Hong Kong of China. Recently, SHM technology has beenextended to field test systems. In this view, SHM can serve as a tool to develop the methods of life-cycleperformance design, evaluation, maintenance and management of bridges; to develop new structuralanalysis methods through validation and feedback from SHM results; and to understand the behavior ofbridges under natural and man-made disasters, rapidly assess the damage and loss of structures over largeregions after disasters, e.g., earthquake, typhoon, flood, etc. It is hoped that combining analytical methods,numerical simulation, small-scale tests and accelerated durability tests with SHM could become the mainengine driving the development of bridge engineering. This paper demonstrates the above viewpoint.
Ziyang Lu,Zehui Yu,Jinbo Dong,Xinyu Xiong,Lin Gao,Minshan Song,Yang Liu,Di Fan,Yongsheng Yan,Pengwei Huo 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2018 NANO Vol.13 No.2
The novel magnetic PW-doped PEDOT (PW@PEDOT) imprinted photocatalyst with good reproducibility was prepared by the surface imprinting technique and microwave heating method. Due to the existence of PW@PEDOT and imprinted cavity in the imprinted layer, the as-prepared magnetic PW@PEDOT imprinted photocatalyst not only had higher photocatalytic activity, but also had the excellent specific recognition ability for selective photodegradation of TC. This paper proposed a new idea to prepare the imprinted photocatalysts.