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Effect of rain on flutter derivatives of bridge decks
Ming Gu,Shu-zhuang Xu 한국풍공학회 2008 Wind and Structures, An International Journal (WAS Vol.11 No.3
Flutter derivatives provide the basis of predicting the critical wind speed in flutter and buffeting analysis of long-span cable-supported bridges. Many studies have been performed on the methods and applications of identification of flutter derivatives of bridge decks under wind action. In fact, strong wind, especially typhoon, is always accompanied by heavy rain. Then, what is the effect of rain on flutter derivatives and flutter critical wind speed of bridges? Unfortunately, there have been no studies on this subject. This paper makes an initial study on this problem. Covariance-driven Stochastic Subspace Identification (SSI in short) which is capable of estimating the flutter derivatives of bridge decks from their steady random responses is presented first. An experimental set-up is specially designed and manufactured to produce the conditions of rain and wind. Wind tunnel tests of a quasi-streamlined thin plate model are conducted under conditions of only wind action and simultaneous wind-rain action, respectively. The flutter derivatives are then extracted by the SSI method, and comparisons are made between the flutter derivatives under the two different conditions. The comparison results tentatively indicate that rain has non-trivial effects on flutter derivatives, especially on and , and thus the flutter critical wind speeds of bridges.
Equivalent static wind loads for stability design of large span roof structures
Gu, Ming,Huang, Youqin Techno-Press 2015 Wind and Structures, An International Journal (WAS Vol.20 No.1
Wind effects on roofs are usually considered by equivalent static wind loads based on the equivalence of displacement or internal force for structural design. However, for large-span spatial structures that are prone to dynamic instability under strong winds, such equivalent static wind loads may be inapplicable. The dynamic stability of spatial structures under unsteady wind forces is therefore studied in this paper. A new concept and its corresponding method for dynamic instability-aimed equivalent static wind loads are proposed for structural engineers. The method is applied in the dynamic stability design of an actual double-layer cylindrical reticulated shell under wind actions. An experimental-numerical method is adopted to study the dynamic stability of the shell and the dynamic instability originating from critical wind velocity. The dynamic instability-aimed equivalent static wind loads of the shell are obtained.
Gu, Ming,Li, Su-Yi,Huang, Xin-En,Lin, Yan,Cheng, Hong-Yan,Liu, Lin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.11
Objective: This study was performed to evaluated the efficacy and safety of continuous infusional paclitaxel and 5-Fu as first-line chemotherapy in patients with advanced esophageal squamous cell cancer (ESCC). Methods: A total of 22 patients with advanced esophageal squamous cell cancer with no indications for surgery and radiation therapy, or recurrent patients were enrolled from October 2008 to November 2010. All were treated with PTX 20 $mg/m^2$ was administered through a 16 hours continuous intravenous infusion on days 1 to 3, 8 and 9. DDP 3.75 $mg/m^2$ was given on days 1 to 4 and 8 to 11, continuous infusional 5-FU over 24-hours on days 1 to 5 and 8 to 12 at a dose of 375 $mg/m^2$, and folacin 60 mg orally synchronized with 5-Fu. The treatment was repeated every 21 days for at least two cycles. Results: 22 cases of all enrolled patients could be evaluated for the effect of treatment: 2 cases were CR, 9 cases PR, 5 cases SD and 2 cases PD, giving an overall response rate of 68.2%(15/22). The median time to progression was 7.0 months. The adverse reactions related to chemotherapy were tolerable; the most common toxic effects were marrow depression, alopecia, and fatigue. Conclusion: Low-dose continuous infusional PTX over 16-hours and 5-fu over 24-hours is a promising regimen with good tolerability in treating patients with advanced esophageal squamous cell cancer.
Effect of rain on flutter derivatives of bridge decks
Gu, Ming,Xu, Shu-Zhuang Techno-Press 2008 Wind and Structures, An International Journal (WAS Vol.11 No.3
Flutter derivatives provide the basis of predicting the critical wind speed in flutter and buffeting analysis of long-span cable-supported bridges. Many studies have been performed on the methods and applications of identification of flutter derivatives of bridge decks under wind action. In fact, strong wind, especially typhoon, is always accompanied by heavy rain. Then, what is the effect of rain on flutter derivatives and flutter critical wind speed of bridges? Unfortunately, there have been no studies on this subject. This paper makes an initial study on this problem. Covariance-driven Stochastic Subspace Identification (SSI in short) which is capable of estimating the flutter derivatives of bridge decks from their steady random responses is presented first. An experimental set-up is specially designed and manufactured to produce the conditions of rain and wind. Wind tunnel tests of a quasi-streamlined thin plate model are conducted under conditions of only wind action and simultaneous wind-rain action, respectively. The flutter derivatives are then extracted by the SSI method, and comparisons are made between the flutter derivatives under the two different conditions. The comparison results tentatively indicate that rain has non-trivial effects on flutter derivatives, especially on and $H_2$ and $A_2$thus the flutter critical wind speeds of bridges.
Isolation and Identification of an Autophagy-inducing Compound from Raphani Semen
Ming-Yao Gu,양현옥,권학철,Min Ok Song,Hyeonseok Ko,차진욱,이원종 한국생약학회 2013 Natural Product Sciences Vol.19 No.3
The autophagy-lysosomal pathway is an important protein degradation system, and its dysfunction has been implicated in a number of neurodegenerative diseases, including Parkinson's disease. Raphani Semen, one of the herbs of Yeoldahanso-tang (YH), has neuroprotective effects via the autophagy pathway. The activity-guided method was used to isolate and identify the components of Raphani Semen. In this experiment, the total extract of Raphani Semen was partitioned to n-butanol, methylene chloride, and water fractions. Flow cytometry data showed that only the water fraction showed autophagy-inducing activity in vitro. Compounds 1 and 2 were isolated from this water fraction by preparative HPLC separation. The structures of compounds 1 and 2 were identified as stachyose and raffinose, respectively, by the analysis of various spectral data (1H NMR, 13C NMR, and MS) and comparisons with standard stachyose and raffinose. Of these two compounds, raffinose showed autophagy-inducing activity in PC12 cells through the mTOR pathway.
Equivalent static wind loads for stability design of large span roof structures
Ming Gu,Youqin Huang 한국풍공학회 2015 Wind and Structures, An International Journal (WAS Vol.20 No.1
Wind effects on roofs are usually considered by equivalent static wind loads based on the equivalence of displacement or internal force for structural design. However, for large-span spatial structures that are prone to dynamic instability under strong winds, such equivalent static wind loads may be inapplicable. The dynamic stability of spatial structures under unsteady wind forces is therefore studied in this paper. A new concept and its corresponding method for dynamic instability-aimed equivalent static wind loads are proposed for structural engineers. The method is applied in the dynamic stability design of an actual double-layer cylindrical reticulated shell under wind actions. An experimental–numerical method is adopted to study the dynamic stability of the shell and the dynamic instability originating from critical wind velocity. The dynamic instability-aimed equivalent static wind loads of the shell are obtained.
Gu Ming,유승훈 한국무역통상학회 2023 무역통상학회지 Vol.23 No.6
RMB internationalization improved in 2013 with the “Belt and Road” initiative. The scheme first regionalized the RMB in Belt and Road nations, then globalized it. Chinese companies’ worldwide development and foreign direct investment have increased due to the “One Belt, One Road” policy. This paper examines how Chinese OFDI affects RMB internationalization under the “Belt and Road” program. The analysis uses ARIMA and combines theoretical and empirical methodologies. The research targets Belt and Road ASEAN nations. The empirical research found that outward foreign direct investment (OFDI) may boost RMB recognition and ASEAN-China economic and financial relations. Thus, it would promote RMB acceptance and globalization in these locations.