French National Network Devoted to Ensure Durable Recycling of Organic Residues in Agriculture:Field Experiment Network, Professional Network and Shared Databases

Michaud Aurelia,Bell Alix,Heurtaux Mathilde,Houot Sabine 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

La formation de l'identité sexuée dans les manuels de lecture de Cours préparatoire en France

MICHAUD Héloïse 프랑스학회 2014 프랑스학연구 Vol.68 No.-

본 연구는 아동들의 정체성 구축, 특히 남자아이 또는 여자아이의 성(싼)정체성이 초등학교에 끼친 영향에 관한 논문이다. 특히 초등학교 1학년 수엽의 교재 내용 속에서 성(性)을 대표하는 것들에 관심을 가졌다. 왜냐하면 6-7세는 아이들이 자신들의 주변의 세계를 구축하는 나이이며 교재는 아동들이 자신의 정체성의 지표를 만들고 형성해나가는 수단이기 때문이다. 특히 고정관념에 의해 성을 대표하는 것들에 대해 관심을 가지고 여섯 종류의 교재 자료집을 선택했다, 이미 굳어진 성(性)을 대표하는 것들이 아이들에게 무엇을 행동 규범으로 제시하는지 알기 위해 조사를 했다. 그 규범들은 차후에 성(性)과 관련된 사회생활에 대한 그들의 시각에 대해 영향을 주고, 진로와 관련하여 그들의 선택을 좌우하는 것들이다. 조사한 교재에서, 여아는 외모, 수동성과 어머니로부터 받은 기질들이 나타나는 반면 남아들은 외향적이며 활동적이고 에너지 넘치며 전복적인 것을 꾀하는 것으로 나타난다. 그래서 이러한 고정관념들이 남아에게는 미래 직업의 활동성과 세계로의 진출을 암시하고, 여아에게는 여인, 어머니, 부인의 미래 역할을 준비하는 것으로 여아들의 활동을 과소평가하고 있다. 교재속의 등장인물들과 동일시하다보면 여아들은 남아들 보다 성공 가능성이 덜해 보인다. 이것이 바로 여아들에게 자신감의 결여 등으로 직업 선택에도 부정적으로 영향을 끼치고 그 결과 여아들은 학교에서는 더 성공하지만 직업의 세계에서는 일자리 가 적으며 월급도 더 적게 받는다는 것을 확인했다.

Inhibitory role of sphingosine 1-phosphate receptor 2 in macrophage recruitment during inflammation.

Michaud, Jason,Im, Dong-Soon,Hla, Timothy Williams Wilkins 2010 JOURNAL OF IMMUNOLOGY Vol.184 No.3

<P>Macrophage recruitment to sites of inflammation is an essential step in host defense. However, the mechanisms preventing excessive accumulation of macrophages remain relatively unknown. The lysophospholipid sphingosine 1-phosphate (S1P) promotes T and B cell egress from lymphoid organs by acting on S1P receptor 1 (S1P(1)R). More recently, S1P(5)R was shown to regulate NK cell mobilization during inflammation, raising the possibility that S1P regulates the trafficking of other leukocyte lineages. In this study, we show that S1P(2)R inhibits macrophage migration in vitro and that S1P(2)R-deficient mice have enhanced macrophage recruitment during thioglycollate peritonitis. We identify the signaling mechanisms used by S1P(2)R in macrophages, involving the second messenger cAMP and inhibition of Akt phosphorylation. In addition, we show that the phosphoinositide phosphatase and tensin homolog deleted on chromosome 10, which has been suggested to mediate S1P(2)R effects in other cell types, does not mediate S1P(2)R inhibition in macrophages. Our results suggest that S1P serves as a negative regulator of macrophage recruitment by inhibiting migration in these cells and identify an additional facet to the regulation of leukocyte trafficking by S1P.</P>

SYMPOSIA / SO5-1 : EXPRESSION OF THE SMALL HSPS OF Drosophila : CELL - AND ORGANELLE - SPECIFIC CHAPERONES ?

(R . M . Tanguay),(S . Michaud),(G . Morrow) 한국생화학분자생물학회 (구 한국생화학회) 1999 6th IUBMB SEOUL CONFERENCE Vol.- No.-

Curing raisins with sulfur dioxide suppresses population growth of Indian meal moth, Plodia interpunctella (Hubner) (Lepidoptera: Pyralidae)

Rezanejad Sirus,Fazel Morteza Mohavedi,Kavusi Aurang,Michaud J.P. 한국응용곤충학회 2022 Journal of Asia-Pacific Entomology Vol.25 No.1

A sulfur dioxide treatment is often used to preserve the color and flavor of raisins. We used a life table approach to examine the effects of residual sulfites on Plodia interpunctella (Hubner) when larvae fed on raisins under controlled laboratory conditions. Raisins were fumigated with 66 g/m 3 or 133 g/m 3 SO 2 for either three or six hours, or received no SO 2 exposure (control). A two sex life table was constructed for insects in each treatment (n = 70 per treatment). Total immature mortality exceeded 90% in 66 g/m 3 SO 2 treatments, and 80% in 133 g/m 3 SO 2 treatments, compared to 28.6% in controls. Sulfur dioxide treatments significantly extended developmental time relative to controls, again more so in the 66 g/m 3 SO 2 treatments than in the 133 g/m 3 treatments, but did not affect the adult longevity of survivors. All SO 2 treatments reduced the fecundity of surviving female moths to a small fraction of controls, without significant differences among them. These effects combined to result in significantly diminished life table parameters in all treatments relative to controls, although generation times were increased more in the 66 g/m 3 SO 2 treatments than in the 133 g/m 3 treatments. These inverse dosagedependent effects may reflect increased feeding avoidance of sulfite residues in the higher dose treatments that resulted in reduced consumption. We conclude that residual sulfur and sulfites deposited on fruit surfaces during SO 2 treatment provide substantial control of P. interpunctella, and should effectively suppress the pro liferation of moths within bulk stores of dried raisins.

Playing snakes and ladders with the common fibular nerve on ultrasound after knee dislocation

Natan Bensoussan,Mathieu Boudier-Revéret,Johan Michaud 영남대학교 의과대학 2022 Yeungnam University Journal of Medicine Vol.39 No.3

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All natural cork composites with suberin-based polyester and lignocellulosic residue

De Oliveira, Hugo,Yoon, Bumyong,Michaud, Vé,ronique,Nam, Jae-Do,Suhr, Jonghwan Elsevier 2017 INDUSTRIAL CROPS AND PRODUCTS Vol.109 No.-

<P><B>Abstract</B></P> <P>Suberin is an aromatic-aliphatic cross-linked polyester structure which constitutes cell wall structures of cork. It is particularly interesting for its use of monomeric compounds towards renewable bio-based polymers. In this study, the extraction of suberin monomers was successfully done by green method using alkaline hydrolysis combined with mechanical grinding. As the mechanical grinding was applied along with hydrolysis process, the maximum yield of depolymerized suberin monomer (DSM) with relatively low energy and less time was acheived. The polarity and functionality of DSM extracted in this study also showed higher values compared to conventional reflux hydrolysis process. Polyesterification and curing behavior of DSM were examined with molecular weights and mechanical properties of the ensuing polyesters. Tensile properties of suberin-based polyesters are reported for the first time that the maximum strength was found to be 7.3MPa while Young‘s modulus was found to be 105MPa. Furthermore, all natural cork composites were fabricated which comprise suberin-based polyester as matrix and lignocellulosic residue as reinforcement, and also reported their significantly enhanced tensile properties showing the great potential as an alternative green polymer composites for various engineering applications.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Suberin extraction process has been developed in efficient way and showed high functionality of suberin monomers, not compromising the maximum yield of suberin monomer. </LI> <LI> The kinetics of polyesterification reaction of suberin monomers showed that the gel point of suberin monomers was estimated to be 3h in 170°C convection oven. </LI> <LI> Synthesis of suberin-based polyesters is optimized by reducing void formations inside the material. </LI> <LI> The maximum tensile strength was found to be 7.3MPa while Young‘s modulus was found to be 105MPa. </LI> <LI> Lignocellulosic residue obtained from extraction process has been incorporated into suberin-based polyester matrix to fabricate all cork-based composites. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>A green composite material was developed by environmentally friendly fabrication process from renewable natural cork, without compromising the mechanical properties of the resultant materials.</P> <P>[DISPLAY OMISSION]</P>

Stress and Manufacturability in Solid-State Lithium-Ion Batteries

Md Raziun Bin Mamtaz,Xavier Michaud,Hongseok Jo,Simon S. Park 한국정밀공학회 2023 International Journal of Precision Engineering and Vol.10 No.4

The increasing demand for higher energy density in energy storage systems has instituted the need for electrodes with higher specific capacity and long-term cyclability. However, conventional Li-ion batteries using liquid electrolytes are incapable of reaching the high energy density requirements due to their incompatibility with these high-capacity electrodes. Moreover, these conventional Li-ion batteries are prone to catch fire due to dendrite growth, interfacial instabilities, liquid leakage, and thermal runaway. In contrast, solid-state batteries (SS-LIBs) are a promising technology which can utilize high theoretical specific capacity anodes such as Li metal and Si-based anodes. SS-LIBs experiences internal stresses in between the layers (of electrodes and electrolyte). During lithiation cycling in a SS-LIB, the electrode layers undergo volumetric, phase, and/or lattice dimensional changes, which induces the structural constraints at the interfaces. These constraints raise internal stresses in different stress concentrated regions, leading to poor interfacial contacts, capacity fading, and possible battery failure. In addition, the practicability of SS-LIBs relies on overcoming the scalability challenges, notably, in handling multilayered structures, homogeneity of the interfacial contact, and a suitable stacking process without damaging the multilayered SS-LIB structure. Herein, we evaluate and discuss the cause and impact of these stress management and manufacturability challenges and provide a review of the studies conducted in tackling these challenges. We aim to guide the readers towards tackling these problems and provide possible shortcomings in these solutions.

Functional Gastrointestinal Disorders Induced by Esophageal Atresia Surgery: Is It Valid in Humans?

( Ugur Halac ),( Marine Revillion ),( Laurent Michaud ),( Frederic Gottrand ),( Christophe Faure ) 대한소화기기능성질환·운동학회 2012 Journal of Neurogastroenterology and Motility (JNM Vol.18 No.4

Background/Aims Functional gastrointestinal disorders (FGID) affect 15%-20% of the general pediatric and adult population. Animal models suggest that a neonatal stress such as invasive procedures and maternal separation could be responsible for visceral hypersensitivity and FGID. We tested the hypothesis that congenital esophageal atresia (EA), a condition corrected during the neonatal period and associated with multiple stresses, is a clinically significant risk factor for the development of FGID later in life. We postulated that, to be clinically significant, the effect of neonatal stress on the incidence of FGID should be as strong as that of enteric infections in the development of irritable bowel syndrome in children. Methods Subjects with EA and healthy controls were enrolled in this multicenter cohort study. Gastrointestinal symptoms were assessed by a questionnaire and FGID was diagnosed using the Rome III criteria. Results Fifty-three children (25 girls, median age, 12 years) with EA were compared to 72 age- and sex-matched controls. Although 11 children with EA (21%) had a FGID diagnosis versus 8 controls (11%), this difference was not significant (χ² = 2.20, P > 0.05). In subjects with EA, the presence of associated malformations, the occurrence of complications during the first month, and the length of hospital stay > 30 days did not influence the incidence of FGID. Chronic abdominal pain was present in 38% of subjects with EA versus 25% of controls (P > 0.05). Conclusions Neonatal stress secondary to surgical correction of EA is not a clinically significant risk factor for the development of FGID in childhood. (J Neurogastroenterol Motil 2012,18:406-411)

Effects of CO2 enrichment, LED inter-lighting, and high plant density on growth of Nicotiana benthamiana used as a host to express influenza virus hemagglutinin H1

Lingling Shang,Linda Gaudreau,Michèle Martel,Dominique Michaud,Steeve Pepin,André Gosselin 한국원예학회 2018 Horticulture, Environment, and Biotechnology Vol.59 No.5

Plants are being recognized as promising hosts for molecular farming and several molecular tools have been developed over the last two decades to optimize recombinant protein yields. However, the effects of basic growth factors on protein yield have been much less studied. Here, we investigated the effects of supplemental light emitting diode (LED) inter-lighting, CO2enrichment, and plant density on growth and recombinant protein yield of Nicotiana benthamiana used as a host to express the vaccine antigen influenza virus hemagglutinin H1. LED inter-lighting improved plant growth and recombinant protein yield on a per-plant basis. CO2 enrichment also enhanced plant growth, but its effect on recombinant protein yield was not significant. By comparison, high plant density decreased recombinant protein production per plant, mainly because of its negative impact on protein accumulation on a per-plant basis. On a whole-crop area basis, supplemental lighting, CO2 enrichment, and high plant density improved plant growth, while only LED inter-lighting and high plant density positively impacted recombinant protein yield. We suggest that LED inter-lighting and an elevated plant density should be used to maximize H1 antigen yield in large-scale protein production systems using N. benthamiana.