http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
연구논문 : 백미밥의 섭취에 따른 영양과 식품 섭취 실태 및 대사증후군 위험수준: 1기(1998), 4기(2007~2009), 6기(2013) 국민건강영양조사 자료를 이용하여
송방방 ( Fang Fang Song ),장진아 ( Jin A Jang ),김양숙 ( Yang Suk Kim ),윤혜려 ( Hei Ryeo Yoon ),조미숙 ( Mi Sook Cho ) 한국식생활문화학회 2015 韓國食生活文化學會誌 Vol.30 No.5
The purpose of this research was to investigate the relationship between white rice consumption and dietary intake, the risk of metabolic syndrome in Korean based on 1st (1998), 4th (2007~2009), 6th (2013) KNHANES. This study included 25,799 subjects who were age 10 or over. Three groups(low, medium, high) were divided according to white rice consumption (per day). In the low group, the meat and oil intake were significantly higher than the high group. In the 1st survey year, the BMI, waist circumstances, hypertriglyceridemia and fasting blood glucose in the high group were higher than other groups, however the 4th and 6th survey year showed no significant results. In the 1st survey year the risk of waist circumstances was higher in the high white rice consumption group and also had high risk with hypertriglyceridemia. Since the lower white rice consumption in 4th than 1st survey year we found no significant results. But in the 6th survey year with the lowest white rice consumption the risk of high diastolic pressure was reduced in high group. Because continuously reduced white rice consumption meantime showed more intake of meat and oil, it can be concluded that defensive effects with the Korean health.
Anticholinesterase and Antioxidant Constituents from <i>Gloiopeltis furcata</i>
Fang, Zhe,Jeong, Su Yang,Jung, Hyun Ah,Choi, Jae Sue,Min, Byung Sun,Woo, Mi Hee The Pharmaceutical Society of Japan 2010 Chemical & pharmaceutical bulletin Vol.58 No.9
<P>Activity-directed isolation of the ethyl acetate, methylene chloride and <I>n</I>-hexane fractions of <I>Gloiopeltis furcata</I> resulted in the isolation of 18 compounds. Their structures were elucidated as 2-(3-hydroxy-5-oxotetrahydrofuran-3-yl)acetic acid (<B>1</B>), glutaric acid (<B>2</B>), succinic acid (<B>3</B>), nicotinic acid (<B>4</B>), (<I>E</I>)-4-hydroxyhex-2-enoic acid (<B>5</B>), cholesterol (<B>6</B>), 7-hydroxycholesterol (<B>7</B>), uridine (<B>8</B>), glycerol (<B>9</B>), 5-(hydroxymethyl)-2-methoxybenzene-1,3-diol (<B>10</B>), (5<I>E</I>,7<I>E</I>)-9-oxodeca-5,7-dienoic acid (<B>11</B>), (<I>Z</I>)-3-ethylidene-4-methylpyrrolidine-2,5-dione (<B>12</B>), dehydrovomifoliol (<B>13</B>), loliolide (<B>14</B>), cholesteryl stearate (<B>15</B>), palmitic acid (<B>16</B>), <I>cis</I>-5,8,11,14,17-eicosapentaenoic acid (<B>17</B>) and α-linolenic acid (<B>18</B>) on the basis of spectroscopic and chemical evidences. Their anticholinesterase and antioxidant activities were evaluated <I>via</I> inhibitory activities on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) as well as scavenging activities on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and peroxynitrite (ONOO<SUP>−</SUP>). All isolated compounds (<B>1</B>—<B>18</B>) exhibited moderate AChE inhibitory activities with IC<SUB>50</SUB> values ranging from 1.14—12.50 μg/ml, whereas <B>1</B>, <B>7</B>, <B>9</B>, <B>17</B>, and <B>18</B> showed mild BChE inhibitory activities with IC<SUB>50</SUB> values ranging from 5.57—15.89 μg/ml. Although most of the compounds isolated were lacking the scavenging activity on DPPH radical and ONOO<SUP>−</SUP>, <B>5</B> and <B>10</B> showed good DPPH radical scavenging activity, and <B>5</B>, <B>10</B>, and <B>16</B> showed potent ONOO<SUP>−</SUP> scavenging activity.</P>
FANG, ZHENGHUAN,JUNG, KYUNG HEE,YAN, HONG HUA,KIM, SOO JUNG,SON, MI KWON,RUMMAN, MARUFA,LEE, HYUNSEUNG,KIM, KI WOON,YOO, HYE-DONG,HONG, SOON-SUN Spandidos Publications 2015 International journal of oncology Vol.47 No.1
<P>Chronic myeloid leukemia (CML) is characterized by a constitutively active Bcr-Abl tyrosine kinase. Although Imatinib has been proven to be an effective drug against CML, its resistance has been observed with disease relapse due to T315I predominant point mutation. Liriodendron tulipifera L., one of the fastest growing hardwood tree species, exerts antioxidant activity and anti-inflammatory effects. However, its anticancer effect has been minimally reported. In this study, we extracted CD-200 from Liriodendron tulipifera L. and investigated its effect on cell survival or apoptosis in CML cells with Bcr-Abl/T315I (BaF3/T315I) as well as wild-type Bcr-Abl (BaF3/WT). CD-200 inhibited cell proliferation in the BaF3/WT cells, and also in the BaF3/T315I cells with Imatinib resistance. Moreover, it strongly inhibited Bcr-Abl signaling pathways in a dose-dependent manner. Also, it significantly increased the sub-G1 phase and the expression of cleaved PARP and caspase-3, as well as the TUNEL-positive apoptotic cells. In addition, we observed that CD-200 induced apoptosis with a loss of mitochondrial membrane potential by decreasing the expression of Mcl-1 and survivin. Furthermore, CD-200 showed a significant inhibition in tumor growth, compared to Imatinib in BaF3/T315I mouse xenograft models. Taken together, our study demonstrates that CD-200 exhibits apoptosis induction and anti-proliferative effect by blocking the Bcr-Abl signaling pathways in the Bcr-Abl/T315I with resistance to Imatinib. We suggest that CD-200 may be a natural product to target Bcr-Abl and overcome Imatinib resistance in CML patients.</P>
Accuracy of computer-guided implant placement in anterior regions
Fang, Yiqin,An, Xueyin,Jeong, Seung-Mi,Choi, Byung-Ho Elsevier 2019 The Journal of prosthetic dentistry Vol.121 No.5
<P><B>Abstract</B></P> <P><B>Statement of problem</B></P> <P>Implant placement in the anterior regions is often challenging because of limited space and bone volume availability.</P> <P><B>Purpose</B></P> <P>The purpose of this clinical study was to investigate the accuracy of computer-guided surgery with a long drill key to place implants in the anterior regions.</P> <P><B>Material and methods</B></P> <P>Computer-guided implant surgery was performed for 32 participants requiring implants in anterior regions. The procedure involved using a 12-mm-long drill key to guide the 2.0-mm-diameter drill. Deviations between the planned and actual implant positions were evaluated by using cone beam computed tomography (CBCT) scans obtained before and after surgery. A <I>t</I> test was used for comparisons between the planned and placed implants and to determine the influence of the arch (maxilla/mandible) and time (immediate/delayed) on accuracy.</P> <P><B>Results</B></P> <P>A total of 40 implants (20 implants in the maxilla and 20 implants in the mandible) were placed. The mean linear deviation was 0.46 mm (range, 0 to 1.15 mm) for the implant shoulder and 0.67 mm (range, 0.14 to 1.19 mm) for the implant apex. The mean angular deviation was 1.40 degrees (range, 0.30 to 2.57 degrees). The mean depth deviation was 0.15 mm (range, 0.10 to 0.82 mm).</P> <P><B>Conclusions</B></P> <P>This clinical study showed that the accuracy of computer-guided implant placement may be enhanced by using a long drill key and may thus enable more accurate implant placement in anterior regions.</P>
Fang, Zhe,Moon, Dong-Cheul,Son, Kun-Ho,Son, Jong-Keun,Min, Byung-Sun,Woo, Mi-Hee Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.1
In this study, quantitative and pattern recognition analysis for the quality evaluation of Cimicifugae Rhizoma using HPLC/UV was developed. For quantitative analysis, three major bioactive phenolic compounds were determined. The separation conditions employed for HPLC/UV were optimized using ODS $C_{18}$ column ($250{\times}4.6mm$, $5{\mu}M$) with isocratic elution of acetonitrile and water with 0.1% phosphoric acid as the mobile phase at a flow rate of 1.0 mL/min and a detection wavelength of 323 nm. These methods were fully validated with respect to the linearity, accuracy, precision, recovery, and robustness. The HPLC/UV method was applied successfully to the quantification of three major compounds in the extract of Cimicifugae Rhizoma. The HPLC analytical method for pattern recognition analysis was validated by repeated analysis of twelve reference samples corresponding to five different species of Cimicifugae Rhizoma and seventeen samples purchased from markets. The results indicate that the established HPLC/UV method is suitable for the quantitative analysis and quality control of multi-components in Cimicifugae Rhizoma.
Quantitative and Pattern Recognition Analyses for the Quality Evaluation of Magnoliae Flos by HPLC
Fang, Zhe,Shen, Chang Min,Moon, Dong-Cheul,Son, Kun-Ho,Son, Jong-Keun,Woo, Mi-Hee Korean Chemical Society 2010 Bulletin of the Korean Chemical Society Vol.31 No.11
In this study, quantitative and pattern recognition analysis for the quality evaluation of Magnoliae Flos using HPLC/UV was developed. For quantitative analysis, eleven major bioactive lignan compounds were determined. The separation conditions employed for HPLC/UV were optimized using ODS $C_{18}$ column ($250{\times}4.6\;mm$, $5\;{\mu}m$) with isocratic elution of acetonitrile and water with 1% acetic acid as the mobile phase at a flow rate of 1.0 mL/min and a detection wavelength of 278 nm. These methods were fully validated with respect to the linearity, accuracy, precision, recovery, and robustness. The HPLC/UV method was applied successfully to the quantification of eleven major compounds in the extract of Magnoliae Flos. The HPLC analytical method for pattern recognition analysis was validated by repeated analysis of twenty one reference samples corresponding to seven different species of Magnoliae Flos and nine samples purchased from market. The results indicate that the established HPLC/UV method is suitable for the quantitative analysis and quality control of multi-components in Magnoliae Flos.
Digital immediate denture: A clinical report
Fang, Jing-Huan,An, Xueyin,Jeong, Seung-Mi,Choi, Byung-Ho Elsevier 2018 The Journal of prosthetic dentistry Vol.119 No.5
<P><B>Abstract</B></P> <P>Fabricating an immediate complete denture in the conventional manner may be complicated and difficult. The purpose of this article was to describe a fully digital workflow used to fabricate an immediate complete denture before removing the teeth and without the use of conventional impressions or stone casts. The digital data for the workflow were acquired using an intraoral scanner and were then used to design the denture base and teeth after deleting any remaining tooth images from the virtual 3-dimensional image of the jaw. The resulting data were exported to a milling machine for denture fabrication.</P>