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Meena, Daleep K.,Akunuri, Shalini,Meena, Preetam,Bhramer, Ashok,Sharma, Shiv D.,Gupta, Rajkumar The Korean Society of Pediatric Gastroenterology 2019 Pediatric gastroenterology, hepatology & nutrition Vol.22 No.4
Purpose: This study aimed to evaluate a possible association between the anti-tissue transglutaminase antibody (anti-tTG) titer and stage of duodenal mucosal damage and assess a possible cut-off value of anti-tTG at which celiac disease (CD) may be diagnosed in children in conjunction with clinical judgment. Methods: This observational study was conducted at a gastroenterology clinic in a tertiary hospital from April 2012 to May 2013. Seventy children between 6-months and 18-years-old with suspected CD underwent celiac serology and duodenal biopsy. Statistical analyses were done using SPSS 16. Diagnostic test values were determined for comparing the anti-tTG titer with duodenal biopsy. An analysis of variance and Tukey-Kramer tests were performed for comparing the means between groups. A receiver operating characteristics curve was plotted to determine various cut-off values of anti-tTG. Results: The mean antibody titer increased with severity of Marsh staging (p<0.001). An immunoglobulin (Ig) A-tTG value at 115 AU/mL had 76% sensitivity and 100% specificity with a 100% positive predictive value (PPV) and 17% negative predictive value (NPV) for diagnosis of CD (p<0.001, 95% confidence interval [CI], 0.75-1). Conclusion: There is an association between the anti-tTG titer and stage of duodenal mucosal injury in children with CD. An anti-tTG value of 115 AU/mL (6.4 times the upper normal limit) had 76% sensitivity, 100% specificity, with a 100% PPV, and 17% NPV for diagnosing CD (95% CI, 0.75-1). This cut-off may be used in combination with clinical judgment to diagnose CD.
Daleep K. Meena,Shalini Akunuri,Preetam Meena,Ashok Bhramer,Shiv D. Sharma,Rajkumar Gupta 대한소아소화기영양학회 2019 Pediatric gastroenterology, hepatology & nutrition Vol.22 No.4
Purpose: This study aimed to evaluate a possible association between the anti-tissue transglutaminase antibody (anti-tTG) titer and stage of duodenal mucosal damage and assess a possible cut-off value of anti-tTG at which celiac disease (CD) may be diagnosed in children in conjunction with clinical judgment. Methods: This observational study was conducted at a gastroenterology clinic in a tertiary hospital from April 2012 to May 2013. Seventy children between 6-months and 18-years-old with suspected CD underwent celiac serology and duodenal biopsy. Statistical analyses were done using SPSS 16. Diagnostic test values were determined for comparing the anti-tTG titer with duodenal biopsy. An analysis of variance and Tukey-Kramer tests were performed for comparing the means between groups. A receiver operating characteristics curve was plotted to determine various cut-off values of anti-tTG. Results: The mean antibody titer increased with severity of Marsh staging ( p <0.001). An immunoglobulin (Ig) A-tTG value at 115 AU/mL had 76% sensitivity and 100% specificity with a 100% positive predictive value (PPV) and 17% negative predictive value (NPV) for diagnosis of CD ( p <0.001, 95% confidence interval [CI], 0.75–1). Conclusion: There is an association between the anti-tTG titer and stage of duodenal mucosal injury in children with CD. An anti-tTG value of 115 AU/mL (6.4 times the upper normal limit) had 76% sensitivity, 100% specificity, with a 100% PPV, and 17% NPV for diagnosing CD (95% CI, 0.75–1). This cut-off may be used in combination with clinical judgment to diagnose CD.
Pt-like hydrogen evolution on a V2O5/Ni(OH)2 electrocatalyst
Meena, Abhishek,Ha, Miran,Chandrasekaran, S. Selva,Sultan, Siraj,Thangavel, Pandiarajan,Harzandi, Ahmad M.,Singh, Bhupendra,Tiwari, Jitendra N.,Kim, Kwang S. The Royal Society of Chemistry 2019 Journal of materials chemistry. A, Materials for e Vol.7 No.26
<P>We report a highly efficient and cost-effective binder-free catalyst for the hydrogen evolution reaction (HER) using V2O5 particles on nickel foam (NF) (V2O5/Ni(OH)2@NF). This low-cost catalyst exhibits Pt-like activity with a low overpotential of 39 mV at 10 mA cm<SUP>−2</SUP> (lowest among V-based materials which are known to be generally non-explosive and safe) and long-term stability in a 1 M KOH solution. The overall performance is highly comparable to that of a commercial 20% Pt/C catalyst on NF. Furthermore, the V2O5/Ni(OH)2@NF outperforms the Pt/C catalyst at a higher current density (100 mA cm<SUP>−2</SUP>) which is more preferable for industrial applications. First principles calculations show that the remarkable HER activity is ascribed to the near-zero adsorption free energy (Δ<I>G</I>H*) on the Ni-site of Ni(OH)2@NF and the Ni- and O-sites of <I>in situ</I> generated V2O5@NF, due to the charge transfer arising from adsorbed O atoms on Ni(111), along with high conductivity of NF. O-adsorption on the Ni transition metal surface downshifts the d-band center of the transition metal, which helps in quick hydrogen desorption by weakening the hydrogen binding strength. As a result, most Ni fcc sites of V2O5/Ni(OH)2@NF are more active than pristine Ni fcc sites. The V2O5/Ni(OH)2@NF catalyst initiates overall water splitting at 1.53 V in a 6 M KOH solution for solar-to-hydrogen generation in a two-electrode set-up using a solar panel.</P>
Aging Mechanism of p-Type Dopingless JLFET: NBTI and Channel-Hot-Carrier Stress
Meena Panchore,Chithraja Rajan 한국전기전자재료학회 2023 Transactions on Electrical and Electronic Material Vol.24 No.2
In this work, an extensive study of the aging mechanisms of the p-type dopingless JLFET (DL JLFET) structure is reported for the first time. The negative-bias-temperature-instability (NBTI) and channel-hot-carrier (CHC) stress conditions are considered for analyzing the aging behavior of p-type DL JLFET. The variations in electrical characteristics of lightly doped DL JLFET are compared with its conventional counterpart JLFET against NBTL and CHC stress. We have shown that JLFET with heavily doped channel region exhibits higher drain current degradation under CHC stress due to high electric field and large gate leakage current. The JLFET has 19% drain current degradation due to CHC stress which is 1.7 times higher than DL JLFET. However, under NBTI stress, the DL JLFET has slightly higher drain current degradation and almost symmetric shift in Vth than JLFET. Hence, this study suggests that dopingless devices are superior candidate for designing aging-resilient and more reliable circuits.
Meena, Vinod Kumar,Ghatak, Himadri Roy The Korean Electrochemical Society 2022 Journal of electrochemical science and technology Vol.13 No.2
The study presents kinetics of degradation and mineralization of an anti-epileptic drug Lamotrigine (LAM) in the aqueous matrix by electrochemical advanced oxidation process (EAOP) on Ti/DSA (Ta<sub>2</sub>O<sub>5</sub>-Ir<sub>2</sub>O<sub>5</sub>) and Stainless Steel (SS) anodes using sodium sulphate as supporting electrolyte. On both the anodes, kinetic behaviour was pseudo-first-order for degradation as well as mineralization of LAM. On Ti/DSA anode, maximum LAM degradation of 75.42% was observed at an associated specific charge of 3.1 (Ah/litre) at a current density of 1.38 mA/cm<sup>2</sup> and 100 ppm Na<sub>2</sub>SO<sub>4</sub> concentration. Maximum mineralization attained was 44.83% at an associated specific charge of 3.1 (Ah/litre) at a current density of 1.38 mA/cm<sup>2</sup> and 50 ppm concentration of Na<sub>2</sub>SO<sub>4</sub> with energy consumption of 2942.71 kWh/kgTOC. Under identical conditions on SS anode, a maximum of 98.92% LAM degradation was marked after a specific charge (Q) of 3.1 (Ah/litre) at a current density of 1.38 mA/cm<sup>2</sup> and 100 ppm concentration of Na<sub>2</sub>SO<sub>4</sub>. Maximum LAM mineralization on SS anode was 98.53%, marked at a specific charge of 3.1 (Ah/litre) at a current density of 1.38 mA/cm<sup>2</sup> and 75 ppm concentration of Na<sub>2</sub>SO<sub>4</sub>, with energy consumption of 1312.17 kWh/kgTOC. Higher Mineralization Current Efficiency (MCE) values were attained for EAOP on SS anode for both degradation and mineralization due to occurrence of combined electro-oxidation and electro-coagulation process in comparison to EAOP on Ti/DSA anode due to occurrence of lone electro-oxidation process.
THE HYDROMAGNETIC FLOW BETWEEN ECCENTRIC CYLINDERS WITH VELOCITY SLIP AT THE CYLINDER WALLS
Meena, S.,Kandaswamy, P. 한국전산응용수학회 1999 Journal of applied mathematics & informatics Vol.6 No.2
The hydrodynamic flow between two eccentric cylinders is examined for small values of modified Reynolds number porosity parameter and the non-dimensional slip velocity parameter in the presence of a radial magnetic field. The stream function and the pres-sure distribution are calculated and the results are presented graph-ically.
Meena Kalyanaraman,Derrick McQueen,Joseph Sykes,Tej Phatak,Farhaan Malik,Preethi S. Raghava 대한소아청소년과학회 2015 Clinical and Experimental Pediatrics (CEP) Vol.58 No.4
Plastibell is one of the three most common devices used for neonatal circumcision in the United States,with a complication rate as low as 1.8%. The Plastibell circumcision device is commonly used underlocal anesthesia for religious circumcision in male neonates, because of cosmetic reasons and easeof use. Occasionally, instead of falling off, the device may get buried under the skin along the shaftof the penis, thereby obstructing the normal flow of urine. Furthermore, the foreskin of neonates ishighly vascularized, and hence, hemorrhage and infection are possible when the skin is cut. Necrosisof penile skin, followed by urethral obstruction and renal failure, is a serious surgical mishap requiringimmediate corrective surgery and medical attention. We report a case of fulminant urosepsis, acuterenal failure, and pyelonephritis in a 4-day-old male neonate secondary to impaction of a Plastibellcircumcision device. Immediate medical management was initiated with fluid resuscitation andmechanical ventilation; thereby correcting life threatening complications. Pediatricians and EmergencyDepartment physicians should be cognizant of the complications from Plastibell circumcision device inorder to institute appropriate and timely management in neonates.
Hydration Products, Morphology and Microstructure of Activated Slag Cement
Meena Murmu,Suresh Prasad Singh 한국콘크리트학회 2014 International Journal of Concrete Structures and M Vol.8 No.1
This paper reports the physical properties and hydration products of slag cement that was prepared by activating ground granulated blast furnace slag with commercial lime and plaster of Paris (POP) as activators. The consistency, setting times and soundness of various mixes of slag-lime-POP is reported. The hydration products and formation of bonds in the paste during setting were studied with the help of SEM, FTIR and XRD tests and the same are correlated to the hydration process. The setting times of the mixes are found to be lower than that of the value prescribed for ordinary Portland cement (OPC). Borax is used as a setting retarder and a borax content of 0.4 % by mass gives setting times that are normally prescribed for OPC. In the early stages of setting C?A?S?H gels are found in this cementing material instead of C?S?H gel, as generally observed in the OPC.