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C. Massimi,A. Borella,S. Kopecky,C. Lampoudis,P. Schillebeeckx,M. C. Moxon,G. Vannini 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23
Transmission, capture and self-indication measurements on^(197)Au have been performed at the neutron time-of-flightfacility GELINA, operated by the European Commission, at EU-JRC-IRMM inBelgium. Part of this work was performed within the framework of the EFNUDATproject, with the objective to improve resonance parameters for the ^(197)Au(n, γ) cross section. Resonance parameters, i.e.,energy, spin, parity, neutron and radiation width, have been deduced in theenergy domain up to 200 eV. A comparison with results of measurementsperformed at RPI and at n_TOF shows a good agreement betweenthe data sets. In particular the nuclear resonance parameters, of the firsts-wave resonance at 4.9 eV, extracted at RPI are in very good agreement withthe results of the present work.
Neutron Resonance Spectroscopy at GELINA
P. Schillebeeckx,A. Borella,S. Kopecky,C. Lampoudis,C. Massimi,M. Moxon 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23
The neutron time-of-flight facility GELINA installed at the JRC-IRMM Geel (B) has been designed to produce cross section data for neutron induced reactions in the resonance region. It is a multi-user facility, providing a pulsed white neutron source, with a neutron energy range between 10 meV and 20 MeV and a time resolution of 1 ns. The research program concentrates on cross section data needs for nuclear energy applications. In this contribution efforts to improve the quality of cross section data in the resonance region are discussed. These efforts include the implementation of self-indication measurements and improved data reduction and resonance analysis procedures. Due to these efforts accurate neutron-induced cross section data and resonance parameters together with their covariance information can be obtained from thermal up to the unresolved resonance region.
( Brigida Barberio ),( Edoardo Vincenzo Savarino ),( Timothy Card ),( Cristina Canova ),( Francesco Baldisser ),( Alessandro Gubbiotti ),( Davide Massimi ),( Matteo Ghisa ),( Fabiana Zingone ) 대한장연구학회 2022 Intestinal Research Vol.20 No.1
Background/Aims: Current literature is lacking in studies comparing the incidence of adverse events (AEs) in patients with inflammatory bowel diseases (IBD) treated with adalimumab (ADA) or vedolizumab (VDZ) in a real-life scenario. Therefore, our primary aim was to compare the AEs occurring in patients taking ADA to those of patients taking VDZ. Methods: In this single center study, data on AEs from IBD patients who underwent treatment with ADA and VDZ were retrospectively collected. AE rates per 100 person-years were calculated. A Cox regression model was used to estimate the hazard ratios of the AEs between the 2 drugs. Results: A total of 16 ADA patients (17.2%) and 11 VDZ patients (7.6%) had AEs causing drug interruption during the study period (P=0.02). Most of the AEs were noninfectious extraintestinal events (50% in ADA and 54.5% in VDZ) while infections accounted for 31.2% of the AEs in patients treated with ADA and 27.3% in those treated with VDZ. The incidence rate of AEs causing withdrawal of therapy was 13.2 per 100 person-years for ADA and 5.3 per 100 person-years for VDZ, corresponding to a 76% lower risk in patients in VDZ. Considering the first year of treatment, we observed 34 subjects treated with ADA (36.5%) having at least 1 AEs and 57 (39.3%) among those taking VDZ (P=0.67). Conclusions: VDZ has a lower incidence rate of AEs causing withdrawal of treatment compared to ADA but a similar risk of AEs not causing drug interruption. Real-life head-to-head studies are still necessary to further explore the safety profile of these drugs. (Intest Res 2022;20:114-123)
Neutron Capture on <SUP>209</SUP>Bi: Determination of the Production Ratio of ^(210m)Bi/^(210g)Bi
F. Gunsing,E. Berthoumieux,A. Borella,T. Belgya,L. Szentmiklosi,P. Schillebeeckx,J. C. Drohe,R. Wynants,N. Colonna,S. Marrone,G. Tagliente,R. Terlizzi,C. Domingo-pardo,J. Tain,T. Martinez,C. Massimi,P 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23
Neutron capture on ^(209)Bi produces either an isomeric state ^(210m)Bi with a half life of 3×10^6 years, or the ground state ^(210g)Bi which decays with a half life of 5 days to the alpha emitter ^(210)Po. Therefore the neutron capture cross section ratio ^(209)Bi(n,γ) ^(210m)^(Bi)/^(210g)Bi plays an important role in predicting the short- and long-term radio-toxicity produced by ^(209)Bi under neutron irradiation. This ratio is dependent on the neutron energy. We have measured this ratio for cold neutrons at the cold neutron beam facility of the Budapest Neutron Centre by observing the population of the ground- and the metastable state using high resolution gamma-ray spectroscopy. The same technique hasbeen used at the pulsed white neutron source GELINA of the IRMM, Geel in combination with the neutron time-of-flight technique. Results for the neutron-energy dependent branching ratio will be presented. In addition we performed simulations using a statistical decay code.