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      • SCOPUSKCI등재

        The Effects of Socio-demographic Characteristics on Indonesian Women's Knowledge of HIV/AIDS: A Cross-sectional Study

        Pradnyani, Putu Erma,Wibowo, Arief,Mahmudah, Mahmudah The Korean Society for Preventive Medicine 2019 Journal of Preventive Medicine and Public Health Vol.52 No.2

        Objectives: The purpose of this study was to characterize Indonesian women's knowledge of HIV/AIDS and to investigate the effects of socio-demographic characteristics thereupon with the goal of supporting the prevention and early detection of HIV/AIDS. Methods: This cross-sectional study was conducted using secondary data from the standard Indonesian Demographic and Health Survey (IDHS) in 2012. A total of 34 984 subjects ranged in age from 15 years to 49 years. Data were analyzed using the chi-square test and logistic regression to identify the effects of socio-demographic characteristics on Indonesian women's knowledge of HIV/AIDS. Results: All socio-demographic characteristics except marital status were related to knowledge of HIV/AIDS among Indonesian women in the univariate analysis (p<0.05). Multivariate analysis revealed that only age group, education level, location of residence, and wealth index were related to Indonesian women's knowledge of HIV/AIDS (p<0.05). Conclusions: Indonesian women's insufficient knowledge related to HIV/AIDS shows that the provision of accurate and comprehensive information related to HIV/AIDS are components of prevention and control interventions that should be improved. With greater knowledge, women are expected to be more likely to determine their own and their partners' human immunodeficiency virus status and to take appropriate preventive steps.

      • SCOPUSKCI등재

        Effect of Tithonia diversifolia Leaf Extract on Leptin, Adiponectin, and Insulin Receptor Levels in Diabetic Rats

        Lailatul Muniroh,Mahmudah,Rondius Solfaine 한국식품영양과학회 2022 Preventive Nutrition and Food Science Vol.27 No.1

        This study aimed to evaluate the effect of Tithonia diversifolia extract (TDE) on leptin, adiponectin, and insulin receptor (IR) concentrations in diabetic rats. Twenty-four Wistar rats were divided into a control and treatment groups (n=6 per group). The control group received normal saline, and the treatment groups received 0.25% sodium carboxy-methyl cellulose, TDE at 100 mg/kg body weight (bw), and catechin at 10 mg/kg bw for 7 days. On day 8, the rats were sacrificed, blood samples were obtained, and leptin, adiponectin, and insulin concentrations were measured using avidin-horseradish peroxidase sandwich-enzyme-linked immunosorbent assay. A calorimetric method was used to measure blood glucose (BG) and total serum cholesterol concentrations. The pancreas and kidneys were collected for the measurement of renal IR and macrophage cluster of differentiation (CD)14 levels using immunohistochemical staining. Acute type 2 diabetes mellitus (T2DM) with elevated BG and total serum cholesterol concentrations was observed in the treatment groups administered streptozotocin. The administration of TDE at 100 mg/kg bw significantly decreased leptin and increased adiponectin concentrations (P≤0.05). Furthermore, TDE treatment significantly increased renal IR and decreased macrophage CD14 levels (P<0.05). Therefore, TDE decreased leptin and BG concentrations by increasing IR levels. TDE also suppressed the necrosis of pancreatic tissues by inhibiting macrophage CD14 expression in diabetic rats. However, further research is necessary to determine the effect of TDE on interleukin and IR levels in the related tissues of patients with T2DM.

      • SCOPUSKCI등재

        Updating Korean Disability Weights for Causes of Disease: Adopting an Add-on Study Method

        Dasom Im,Noor Afif Mahmudah,Seok-Jun Yoon,Young-Eun Kim,Don-Hyung Lee,Yeon-hee Kim,Yoon-Sun Jung,Minsu Ock The Korean Society for Preventive Medicine 2023 예방의학회지 Vol.56 No.4

        Objectives: Disability weights require regular updates, as they are influenced by both diseases and societal perceptions. Consequently, it is necessary to develop an up-to-date list of the causes of diseases and establish a survey panel for estimating disability weights. Accordingly, this study was conducted to calculate, assess, modify, and validate disability weights suitable for Korea, accounting for its cultural and social characteristics. Methods: The 380 causes of disease used in the survey were derived from the 2019 Global Burden of Disease Collaborative Network and from 2019 and 2020 Korean studies on disability weights for causes of disease. Disability weights were reanalyzed by integrating the findings of an earlier survey on disability weights in Korea with those of the additional survey conducted in this study. The responses were transformed into paired comparisons and analyzed using probit regression analysis. Coefficients for the causes of disease were converted into predicted probabilities, and disability weights in 2 models (model 1 and 2) were rescaled using a normal distribution and the natural logarithm, respectively. Results: The mean values for the 380 causes of disease in models 1 and 2 were 0.488 and 0.369, respectively. Both models exhibited the same order of disability weights. The disability weights for the 300 causes of disease present in both the current and 2019 studies demonstrated a Pearson correlation coefficient of 0.994 (p=0.001 for both models). This study presents a detailed add-on approach for calculating disability weights. Conclusions: This method can be employed in other countries to obtain timely disability weight estimations.

      • KCI등재

        The Effects of Socio-demographic Characteristics on Indonesian Women’s Knowledge of HIV/AIDS: A Cross-sectional Study

        Putu Erma Pradnyani,Arief Wibowo,Mahmudah 대한예방의학회 2019 Journal of Preventive Medicine and Public Health Vol.52 No.2

        Objectives: The purpose of this study was to characterize Indonesian women’s knowledge of HIV/AIDS and to investigate the effects of socio-demographic characteristics thereupon with the goal of supporting the prevention and early detection of HIV/AIDS. Methods: This cross-sectional study was conducted using secondary data from the standard Indonesian Demographic and Health Survey (IDHS) in 2012. A total of 34 984 subjects ranged in age from 15 years to 49 years. Data were analyzed using the chi-square test and logistic regression to identify the effects of socio-demographic characteristics on Indonesian women’s knowledge of HIV/AIDS. Results: All socio-demographic characteristics except marital status were related to knowledge of HIV/AIDS among Indonesian women in the univariate analysis (p<0.05). Multivariate analysis revealed that only age group, education level, location of residence, and wealth index were related to Indonesian women’s knowledge of HIV/AIDS (p<0.05). Conclusions: Indonesian women’s insufficient knowledge related to HIV/AIDS shows that the provision of accurate and comprehensive information related to HIV/AIDS are components of prevention and control interventions that should be improved. With greater knowledge, women are expected to be more likely to determine their own and their partners’ human immunodeficiency virus status and to take appropriate preventive steps.

      • SCIESCOPUSKCI등재

        Overview of Helicobacter pylori Infection in Indonesia: What Distinguishes It from Countries with High Gastric Cancer Incidence?

        ( Muhammad Miftahussurur ),( Langgeng Agung Waskito ),( Kartika Afrida Fauzia ),( Isna Mahmudah ),( Dalla Doohan ),( I Ketut Adnyana ),( Ali Khomsan ),( Neneng Ratnasari ),( Yudith Annisa Ayu Rezkitha 대한소화기학회 2021 Gut and Liver Vol.15 No.5

        Helicobacter pylori infects more than half the human population. However, the prevalence in Indonesia is low, as is the prevalence of gastric cancer. Hence, it could be instructive to compare these prevalence rates and their determining factors with those of countries that have high gastric cancer incidence. Ethnicity and genetic characteristics of H. pylori are important determinants of the H. pylori infection rate in Indonesia. The infection rate is higher in Bataknese, Papuans and Buginese than in Javanese, the predominant ethnic group. Ethnicity is also an important determinant of the genetic characteristics of H. pylori. Analysis of CagA in the EPIYA segment showed that the predominant genotypes in Papuans, Bataknese and Buginese are ABB-, ABDand ABC-type CagA, respectively. Meanwhile, in the countries with high gastric cancer incidence, almost all strains had East Asian type CagA. An antibiotic susceptibility evaluation showed that the standard triple therapy can still be used with caution in several cities. There is a very high rate of resistance to second-line regimens such as levofloxacin and metronidazole. Recent studies have shown that furazolidone, rifabutin and sitafloxacin are potential alternative treatments for antibiotic-resistant H. pylori infection in Indonesia. Rather than focusing on early detection and eradication as in countries with high gastric cancer prevalence, countries with low gastric cancer prevalence should focus on screening the several groups that have a high risk of gastric cancer. (Gut Liver 2021;15:653-665)

      • KCI등재

        Safeguarding manuscript-reading tradition as living heritage through ritual: mocoan tradition of an Osing family in Banyuwangi, Indonesia

        Agus Iswanto,Wiwin Indiarti,Mashuri,M. Agus Noorbani,Mahmudah Nur,Fiqru Mafar,Sastri Sunarti 국립민속박물관 2023 International Journal of Intangible Heritage Vol.18 No.-

        Manuscript-reading tradition in Indonesia has recevied little attention by scholars, while in fact this tradition is still practised by communities, in various rituals which may be called ‘living manuscripts’. This study explains how the manuscript-reading tradition can be maintained and preserved as a living heritage. This study focuses on a manuscript-reading session related to a ritual – namely, the mocoan lontar Hadis Dagang – supported only by one Osing family in Banyuwangi, East Java, Indonesia. The study was conducted based on the manuscript, manuscript-reading tradition and the associated ritual, thus requiring an interdisciplinary approach of manuscript studies, tradition studies and community studies. The findings indicate that – a tradition of manuscript reading maintained and preserved by a ritual – can be a living heritage and plays a role in safeguarding another intangible cultural heritage contained in these traditions. The ritual and manuscript-reading tradition, however, are under threat because the family members can no longer perform the manuscript-reading tradition, even though they support the tradition.

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