미세각막절개도 헤드의 선택을 통한 맞춤식각막절개방식의 라식

강민호,송유미,강성민,박영숙,최철영,이윤정,이병로.Min Ho Kang. M.D.. Yoo Mi Song. M.D.. Sung Min Kang. M.D.. Young Sook Park. M.D.. Chul Young Choi. M.D.. Yoon Jung Lee. M.D.. Byung Ro Lee. M.D. 대한안과학회 2006 대한안과학회지 Vol.47 No.2

Purpose: To compare the intraoperative and postoperative complication rates and visual outcomes with M2 130 head (thick flap group) and M2 110 head (thin flap group). Methods: One-hundred-ninety-five eyes of 104 patients who underwent LASIK with the Moria M2 microkeratome and Allegretto-wave laser were reviewed retrospectively. Selection of M2 heads was based on preoperative pachymetry and estimated ablation depth. Intraoperative and postoperative flap-related complications, mean postoperative uncorrected visual acuity (UCVA), and mean spherical equivalent (MSE) were evaluated and compared. Results: Mean follow-up was 8.1 months. The number of eyes, preoperative MSE and mean corneal thickness of M2 130 were 115, -4.04±1.63diopter (D) and 549.40±39.16??m, and 85, -6.61±3.43D and 525.16±24.53 ?m, respectively, in the 110 head group. Mean UCVA and MSE at postoperative 1 week, 3 months and 6 months were 1.00±0.18, -0.26±0.49D; 1.07±0.68, -0.40±0.51D; and 1.01±0.22, -0.51±0.50D, respectively, in the 130 head group, and 0.90±0.23, -0.46±1.02D; 0.91±0.23, -0.67±0.79D; 0.85±0.46, -0.75±0.88D, respectively, in the 110 head group. There were no significant differences in intraoperative and postoperative flap-related complication rates between the two groups (p=0.316). There were no statistically significant differences in postoperative mean UCVA or MSE between the two groups (p>0.05), except for MSE at the third and sixth postoperative months (p=0.005, 0.013). Conclusions: Proper selection of M2 heads by preoperative pachymetry allowed for an adequate residual stroma bed with good visual outcome. Utilizing one single microkeratome and switching between two heads was advantageous and cost-effective.

비타민 D3 의 경구투여 또는 자외선 조사가 브로일러 병아리의 증체 및 비타민 D3 대사에 미치는 영향

장윤환(Y . H . Chiang),황선일(S . I . Hwang),김중달(J . D . Kim),M . F . Holick(M . F . Holick) 한국영양사료학회 1995 韓國營養飼料學會誌 Vol.19 No.6

Vitamin D Is Required for IFN- -Mediated Antimicrobial Activity of Human Macrophages

Fabri, M.,Stenger, S.,Shin, D.-M.,Yuk, J.-M.,Liu, P. T.,Realegeno, S.,Lee, H.-M.,Krutzik, S. R.,Schenk, M.,Sieling, P. A.,Teles, R.,Montoya, D.,Iyer, S. S.,Bruns, H.,Lewinsohn, D. M.,Hollis, B. W.,Hew American Association for the Advancement of Scienc 2011 Science translational medicine Vol.3 No.104

<P>Control of tuberculosis worldwide depends on our understanding of human immune mechanisms, which combat the infection. Acquired T cell responses are critical for host defense against microbial pathogens, yet the mechanisms by which they act in humans remain unclear. We report that T cells, by the release of interferon-γ (IFN-γ), induce autophagy, phagosomal maturation, the production of antimicrobial peptides such as cathelicidin, and antimicrobial activity against Mycobacterium tuberculosis in human macrophages via a vitamin D-dependent pathway. IFN-γ induced the antimicrobial pathway in human macrophages cultured in vitamin D-sufficient sera, but not in sera from African-Americans that have lower amounts of vitamin D and who are more susceptible to tuberculosis. In vitro supplementation of vitamin D-deficient serum with 25-hydroxyvitamin D3 restored IFN-γ-induced antimicrobial peptide expression, autophagy, phagosome-lysosome fusion, and antimicrobial activity. These results suggest a mechanism in which vitamin D is required for acquired immunity to overcome the ability of intracellular pathogens to evade macrophage-mediated antimicrobial responses. The present findings underscore the importance of adequate amounts of vitamin D in all human populations for sustaining both innate and acquired immunity against infection.</P>

Survey of heating and current drive for K-DEMO

Mikkelsen, D.R.,Kessel, C.E.,Poli, F.M.,Bertelli, N.,Kim, K. International Atomic Energy Agency 2018 Nuclear fusion Vol.58 No.3

<P>We present calculations of heating and current drive by neutral injection and by electromagnetic waves in the ion cyclotron, helicon, lower hybrid, and electron cyclotron frequency ranges for the steady state burn conditions in a K-DEMO configuration with <img ALIGN='MIDDLE' ALT='$I_{\rm p}=12.3$ ' SRC='http://ej.iop.org/images/0029-5515/58/3/036014/nfaaa4d2ieqn001.gif'/> MA, <I>a</I>  =  2.1 m, <img ALIGN='MIDDLE' ALT='$R_{\rm o}=6.8$ ' SRC='http://ej.iop.org/images/0029-5515/58/3/036014/nfaaa4d2ieqn002.gif'/> m, <img ALIGN='MIDDLE' ALT='$B_{\rm o}=7.4$ ' SRC='http://ej.iop.org/images/0029-5515/58/3/036014/nfaaa4d2ieqn003.gif'/> T, <img ALIGN='MIDDLE' ALT='$ \newcommand{\nebar}{{\overline{n}_{\rm e}}} \nebar=1.1 \times 10^{20}$ ' SRC='http://ej.iop.org/images/0029-5515/58/3/036014/nfaaa4d2ieqn004.gif'/> m<SUP>−3</SUP>, <img ALIGN='MIDDLE' ALT='$T(0)=40$ ' SRC='http://ej.iop.org/images/0029-5515/58/3/036014/nfaaa4d2ieqn005.gif'/> keV, and <img ALIGN='MIDDLE' ALT='$Z_{\rm eff}=1.5$ ' SRC='http://ej.iop.org/images/0029-5515/58/3/036014/nfaaa4d2ieqn006.gif'/>. Lower hybrid wave current drive calculations comprise a 2D scan over poloidal launcher location and launched <img ALIGN='MIDDLE' ALT='$ \newcommand{\Nparallel}{{n_{\Vert}}} \Nparallel$ ' SRC='http://ej.iop.org/images/0029-5515/58/3/036014/nfaaa4d2ieqn007.gif'/>, at a fixed frequency of 5 GHz. An ICRF frequency scan over 50–100 MHz is based on an ITER-like ICRF midplane antenna; the absorption calculation includes thermal D, T, He, Ar, and W as well as suprathermal beam ions and alphas. Helicon fast wave performance is surveyed by varying frequency over 0.6–2.5 GHz, launched <img ALIGN='MIDDLE' ALT='$ \newcommand{\Nparallel}{{n_{\Vert}}} \Nparallel$ ' SRC='http://ej.iop.org/images/0029-5515/58/3/036014/nfaaa4d2ieqn008.gif'/> from  −1.6 to  −3, and launcher position from top to bottom on the low-field side. An ITER-like 1 MeV neutral beam system with quasi-tangential geometry is scanned over elevation to vary the targeted minor radius. The electron cyclotron survey varies the frequency (190–300 GHz), launcher poloidal location, and the poloidal and toroidal direction of the launched waves. We report for each system the range of minor radius in which current is driven, the current drive efficiency, the optimal system parameters, and typical profiles of driven current. Electron and ion heating profiles are reported for the ICRF and NBI systems.</P>

RF 스위치 적용을 위한 박막 PZT 엑추에이터의 d<SUB>31</SUB> 구동과 d<SUB>33</SUB> 구동 특성 비교

신민재(M. J. Shin),서영호(Y. H. Seo),최두선(D-S. Choi),황경현(K-H. Hwang) 한국정밀공학회 2006 한국정밀공학회 학술발표대회 논문집 Vol.2006 No.5월

In this work, we present the comparison between d<SUB>31</SUB> and d<SUB>33</SUB> mode characterization using the PZT micro-actuator for large displacement. The PZT micro-actuator consisted of Si, PZT, and Pt layer on SOI wafer. The electrode shapes were laminated and interdigitated for d<SUB>31</SUB> and d<SUB>33</SUB> mode, respectively. In order to characterize the actuation mode, we measured the displacement using laser interferometer. The maximum displacement of d<SUB>31</SUB> mode was 12.2㎛ at 10V, the actuation characterization of d<SUB>31</SUB> was better than that of d<SUB>33</SUB> mode. We estimated that displacement of d<SUB>33</SUB> mode would be larger than that of d<SUB>31</SUB> above 30V.

Cyclobuxine D의 토끼 적출 장관에 대한 작용

이종화,박영현,조병헌,김종배,김정목,김유재,김천숙,차영덕,김영석 최신의학사 1988 最新醫學 Vol.31 No.1

한국인에서 DXS7132 유전좌와 GATA31D10 유전좌의 다형성에 관한 연구

안종성,장영길,이숭덕,신창호,이윤성,이정빈 大韓法醫學會 2000 대한법의학회지 Vol.24 No.1

The validation study for two STR loci on X-chromosome, DXS7132 and GATA31D10, was done including allelic distribution and frequency of each allele to use these results for individual identification and paternity testing. For 496 unrelated Koreans, above two STR loci were amplified simultaneously using duplex PCR amplification method. The amplified products were analyzed by polyarylamide gel electrophoresis followed by silver staining. In male DXS7132 locus revealed 7 different alleles ranging from 276bp to 300bp. The largest allele was consisted of 14 repetition of [TCTA] unit and took 0.3417. The allele 15 followed next as 0.3165 and allele 13 as 0.1726. In female general distribution was same except one allele, allele 18 was found additionally. The heterozygosity was 0.7706 and 23 different genotypes were found. Polymorphism information content(PIC) was 0.727. Two cases of mutation were noted in DXS7132 locus In both male and femal 7 different alleles were noted in GATA31D10 locus and the alleles ranged from 195bp to 231bp. The allele 15(199bp) took the majority of all as 0.825. The other alleles showed rather relatively low frequency. The heterozygosity was 0.2385 and 11 different genotypes were found. PIC was 0.2521, and no mutation was noted in GATA31D10 locus. Considering these two loci together, 22 different halpotype were noted.

Directly comparing GW150914 with numerical solutions of Einstein’s equations for binary black hole coalescence

Abbott, B. P.,Abbott, R.,Abbott, T. D.,Abernathy, M. R.,Acernese, F.,Ackley, K.,Adams, C.,Adams, T.,Addesso, P.,Adhikari, R. X.,Adya, V. B.,Affeldt, C.,Agathos, M.,Agatsuma, K.,Aggarwal, N.,Aguiar, O. American Physical Society 2016 Physical Review D Vol.94 No.6

<P>We compare GW150914 directly to simulations of coalescing binary black holes in full general relativity, including several performed specifically to reproduce this event. Our calculations go beyond existing semianalytic models, because for all simulations-including sources with two independent, precessing spins - we perform comparisons which account for all the spin-weighted quadrupolar modes, and separately which account for all the quadrupolar and octopolar modes. Consistent with the posterior distributions reported by Abbott et al. [Phys. Rev. Lett. 116, 241102 (2016)] (at the 90% credible level), we find the data are compatible with a wide range of nonprecessing and precessing simulations. Follow-up simulations performed using previously estimated binary parameters most resemble the data, even when all quadrupolar and octopolar modes are included. Comparisons including only the quadrupolar modes constrain the total redshifted mass M-z epsilon [64 M-circle dot - 82 M-circle dot], mass ratio 1/q = m(2)/m(1) epsilon [0.6; 1], and effective aligned spin chi(eff) epsilon [-0.3, 0.2] where chi(eff) = (S-1/m(1)+S-2/m(2)). (L) over cap /M. Including both quadrupolar and octopolar modes, we find the mass ratio is even more tightly constrained. Even accounting for precession, simulations with extreme mass ratios and effective spins are highly inconsistent with the data, at any mass. Several nonprecessing and precessing simulations with similar mass ratio and chi(eff) are consistent with the data. Though correlated, the components' spins (both in magnitude and directions) are not significantly constrained by the data: the data is consistent with simulations with component spin magnitudes a(1,2) up to at least 0.8, with random orientations. Further detailed follow-up calculations are needed to determine if the data contain a weak imprint from transverse (precessing) spins. For nonprecessing binaries, interpolating between simulations, we reconstruct a posterior distribution consistent with previous results. The final black hole's redshifted mass is consistent with M-f,M-z in the range 64.0 M-circle dot - 73.5 M-circle dot and the final black hole's dimensionless spin parameter is consistent with a(f) = 0.62-0.73. As our approach invokes no intermediate approximations to general relativity and can strongly reject binaries whose radiation is inconsistent with the data, our analysis provides a valuable complement to Abbott et al.</P>

Measurement of D^*+/- meson production in e⁺/-p scattering at low Q²

ZEUS Collaboration,Chekanov, S.,Derrick, M.,Magill, S.,Miglioranzi, S.,Musgrave, B.,Nicholass, D.,Repond, J.,Yoshida, R.,Mattingly, M.C.K.,Jechow, M.,Pavel, N.,Yagues Molina, A.G.,Antonelli, S.,Antoni North-Holland Pub. Co 2007 Physics letters: B Vol.649 No.2

The production of D<SUP>*+</SUP>/-(2010) mesons in e<SUP>+</SUP>/-p scattering in the range of exchanged photon virtuality 0.05<Q<SUP>2</SUP><0.7 GeV<SUP>2</SUP> has been measured with the ZEUS detector at HERA using an integrated luminosity of 82 pb<SUP>-1</SUP>. The decay channels D<SUP>*+</SUP>->D<SUP>0</SUP>π<SUP>+</SUP> with D<SUP>0</SUP>->K<SUP>-</SUP>π<SUP>+</SUP> and corresponding antiparticle decay were used to identify D<SUP>*</SUP> mesons and the ZEUS beampipe calorimeter was used to identify the scattered electron. Differential D<SUP>*</SUP> cross sections as functions of Q<SUP>2</SUP>, inelasticity, y, transverse momentum of the D<SUP>*</SUP> meson, p<SUB>T</SUB>(D<SUP>*</SUP>), and pseudorapidity of the D<SUP>*</SUP> meson, η(D<SUP>*</SUP>), have been measured in the kinematic region 0.02<y<0.85, 1.5<p<SUB>T</SUB>(D<SUP>*</SUP>)<9.0 GeV and |η(D<SUP>*</SUP>)|<1.5. The measured differential cross sections are in agreement with two different NLO QCD calculations. The cross sections are also compared to previous ZEUS measurements in the photoproduction and DIS regimes.

早期破膜에 關한 臨床的 考察

許湘,吳文愛,安東源,申吳永 대한산부인과학회 1972 Obstetrics & Gynecology Science Vol.15 No.7