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      • KCI등재

        Stress concentrations around a circular hole in an infinite plate of arbitrary thickness

        Longchao Dai,Xinwei Wang,Feng Liu 국제구조공학회 2010 Structural Engineering and Mechanics, An Int'l Jou Vol.34 No.2

        This paper presents theoretical solutions for the three-dimensional (3D) stress field in an infinite isotropic elastic plate containing a through-the-thickness circular hole subjected to far-field inplane loads by using Kane and Mindlin’s assumption. The dangerous position, where the premature fracture or failure of the plate will take place, the expressions of the tangential stress at the surface of the hole and the out-of-plane stress constraint factor are found in a concise, explicit form. Based on the present theoretical solutions, a comprehensive analysis is performed on the deviated degree of the in-plane stresses from the related plane stress solutions, stress concentration and out-of-plane constraint, and the emphasis has been placed on the effects of the plate thickness, Poisson’s ratio and the far-field in-plane loads on the stress field. The analytical solution shows that the effects of the plate thickness and Poisson’s ratio on the deviation of the 3D in-plane stress components is obvious and could not be ignored, although their effects on distributions of the in-plane stress components are slight, and that the effect of the farfield in-plane loads is just on the contrary of that of the above two. When only the shear stress is loaded at far field, the stress concentration factor reach its peak value about 8.9% higher than that of the plane stress solutions, and the out-of-plane stress constraint factor can reach 1 at the surface of the hole and is the biggest among all cases considered.

      • SCIESCOPUS

        Stress concentrations around a circular hole in an infinite plate of arbitrary thickness

        Dai, Longchao,Wang, Xinwei,Liu, Feng Techno-Press 2010 Structural Engineering and Mechanics, An Int'l Jou Vol.34 No.2

        This paper presents theoretical solutions for the three-dimensional (3D) stress field in an infinite isotropic elastic plate containing a through-the-thickness circular hole subjected to far-field in-plane loads by using Kane and Mindlin's assumption. The dangerous position, where the premature fracture or failure of the plate will take place, the expressions of the tangential stress at the surface of the hole and the out-of-plane stress constraint factor are found in a concise, explicit form. Based on the present theoretical solutions, a comprehensive analysis is performed on the deviated degree of the in-plane stresses from the related plane stress solutions, stress concentration and out-of-plane constraint, and the emphasis has been placed on the effects of the plate thickness, Poisson's ratio and the far-field in-plane loads on the stress field. The analytical solution shows that the effects of the plate thickness and Poisson's ratio on the deviation of the 3D in-plane stress components is obvious and could not be ignored, although their effects on distributions of the in-plane stress components are slight, and that the effect of the far-field in-plane loads is just on the contrary of that of the above two. When only the shear stress is loaded at far field, the stress concentration factor reach its peak value about 8.9% higher than that of the plane stress solutions, and the out-of-plane stress constraint factor can reach 1 at the surface of the hole and is the biggest among all cases considered.

      • KCI등재

        Identifying long non-coding RNAs and characterizing their functional roles in swine mammary gland from colostrogenesis to lactogenesis

        Shi Lijun,Zhang Longchao,Wang Ligang,Liu Xin,Gao Hongmei,Hou Xinhua,Zhao Fuping,Yan Hua,Cai Wentao,Wang Lixian 아세아·태평양축산학회 2022 Animal Bioscience Vol.35 No.6

        Objective: This study was conducted to identify the functional long non-coding RNAs (lncRNAs) for swine lactation by RNA-seq data of mammary gland. Methods: According to the RNA-seq data of swine mammary gland, we screened lncRNAs, performed differential expression analysis, and confirmed the functional lncRNAs for swine lactation by validation of genome wide association study (GWAS) signals, functional annotation and weighted gene co-expression network analysis (WGCNA). Results: We totally identified 286 differentially expressed (DE) lncRNAs in mammary gland at different stages from 14 days prior to (-) parturition to day 1 after (+) parturition, and the expressions of most of lncRNAs were strongly changed from day –2 to day +1. Further, the GWAS signals of sow milk ability trait were significantly enriched in DE lncRNAs. Functional annotation revealed that these DE lncRNAs were mainly involved in mammary gland and lactation developing, milk composition metabolism and colostrum function. By performing weighted WGCNA, we identified 7 out of 12 lncRNA-mRNA modules that were highly associated with the mammary gland at day –14, day –2, and day +1, in which, 35 lncRNAs and 319 mRNAs were involved. Conclusion: This study suggested that 18 lncRNAs and their 20 target genes were promising candidates for swine parturition and colostrum occurrence processes. Our research provided new insights into lncRNA profiles and their regulating mechanisms from colostrogenesis to lactogenesis in swine. Objective: This study was conducted to identify the functional long non-coding RNAs (lncRNAs) for swine lactation by RNA-seq data of mammary gland.Methods: According to the RNA-seq data of swine mammary gland, we screened lncRNAs, performed differential expression analysis, and confirmed the functional lncRNAs for swine lactation by validation of genome wide association study (GWAS) signals, functional annotation and weighted gene co-expression network analysis (WGCNA).Results: We totally identified 286 differentially expressed (DE) lncRNAs in mammary gland at different stages from 14 days prior to (-) parturition to day 1 after (+) parturition, and the expressions of most of lncRNAs were strongly changed from day –2 to day +1. Further, the GWAS signals of sow milk ability trait were significantly enriched in DE lncRNAs. Functional annotation revealed that these DE lncRNAs were mainly involved in mammary gland and lactation developing, milk composition metabolism and colostrum function. By performing weighted WGCNA, we identified 7 out of 12 lncRNA-mRNA modules that were highly associated with the mammary gland at day –14, day –2, and day +1, in which, 35 lncRNAs and 319 mRNAs were involved.Conclusion: This study suggested that 18 lncRNAs and their 20 target genes were promising candidates for swine parturition and colostrum occurrence processes. Our research provided new insights into lncRNA profiles and their regulating mechanisms from colostrogenesis to lactogenesis in swine.

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