Classification of Pathological Voice Signal with Severe Noise Component

Li, Tao,Jo, Cheolwoo 한국음성과학회 2003 음성과학 Vol.10 No.4

In this paper we tried to classify the pathological voice signal with severe noise component based on two different parameters, the spectral slope and the ratio of energies in the harmonic and noise components (HNR). The spectral slope is obtained by using a curve fitting method and the HNR is computed in cepstrum quefrency domain. Speech data from normal peoples and patients are collected, diagnosed and divided into three different classes (normal, relatively less noisy and severely noisy data). The mean values and the standard deviations of the spectral slope and the HNR are computed and compared with in the three kinds of data to characterize and classify the severely noisy pathological voice signals from others.

Transcriptome analysis reveals distinct innate immunity and ribosomal response at early stage of AcMNPV infection in haemocyte of silkworm resistant and susceptible strains

Li Tao,Qin Sheng,Sun Xia,Zhang Kai-xiang,Ding Xin-yi,Wang Xue-yang,Li Muwang 한국응용곤충학회 2022 Journal of Asia-Pacific Entomology Vol.25 No.3

Baculoviruses are enveloped rod-shaped viruses that with circular double-stranded and large DNA genome. Baculoviruses successfully invade by using the host factors, especially at the process of establishing early infection. In this study, we investigated the different resistant strains of silkworm in response to AcMNPV early infection by RNA-sequencing. Our data revealed that the genes involved in innate immunity and ribosomal proteins were suppressed and cytoskeleton were induced in susceptible strain p50, thus facilitating the viral replication. However, in resistant strain C108, the genes participated in endocytosis and RNA transport were down-regulated, while up-regulation of ribosomal proteins and energy metabolic to inhibit the infection of the virus. These data provide a new sight of the initial host transcriptional responses to viral infection in silkworm.

Predictive value of preoperative lymphocyte-to-monocyte ratio for patients with upper tract urothelial carcinoma

Li, Tao,Xu, Hang,Yang, Lu,Tan, Ping,Wei, Qiang Elsevier 2019 Clinica chimica acta Vol.492 No.-

<P><B>Abstract</B></P> <P><B>Background</B></P> <P>To determine the predictive value of preoperative lymphocyte-to-monocyte ratio (LMR) for pathological and survival outcomes in upper tract urothelial carcinoma (UTUC) after radical nephroureterectomy (RNU).</P> <P><B>Methods</B></P> <P>This retrospective study included 704 UTUC patients between 2008 and 2017. We used a cutoff LMR of 3.6 to evaluate its relationship with oncological outcomes after RNU, using the Kaplan–Meier method and logistic regression models.</P> <P><B>Results</B></P> <P>During median follow-up of 39 months, decreased preoperative LMR was an independent predictor of poor pathological outcomes. Kaplan–Meier analysis revealed that patients with low LMR (<3.6) had poor cancer-specific survival (CSS), recurrence-free survival (RFS), and overall survival (OS); this prognostic value was ascertained for patients with high pathological grade and more advanced stage UTUC, but not for patients with low pathological features. Multivariate Cox proportional hazards model revealed that low LMR was an independent predictor of poor CSS, RFS and OS [hazard ratio (HR) = 1.42, <I>P</I> = 0.02; HR = 1.39, <I>P</I> = 0.008; HR = 1.38, <I>P</I> = 0.017, respectively].</P> <P><B>Conclusion</B></P> <P>Preoperative low LMR was an independent predictor of poor pathological and oncological outcomes of UTUC after RNU. Subgroup analysis confirmed that the prognostic value of LMR was confined to patients with a high pathological grade and more advanced stage tumor.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Preoperative low lymphocyte-to-monocyte ratio (LMR) predicts worse pathologic result for upper tract urothelial carcinoma (UTUC) patients after radical nephroureterectomy (RNU). </LI> <LI> Preoperative low LMR is associated with poor clinical outcomes for UTUC patients after RUN. </LI> <LI> Preoperative low LMR exert a prognostic value mainly for UTUC patient with high pathologic grade and stage tumor. </LI> </UL> </P>

Comparison of structural features and in vitro digestibility of purple yam (Dioscorea alata L.) resistant starches by autoclaving and multi-enzyme hydrolysis

Li, Tao,An, Fengping,Teng, Hui,Huang, Qun,Zeng, Feng,Song, Hongbo 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.1

Resistant starches (RS) were prepared from purple yam by dual autoclaving-retrogradation (DAS), and pullulanase debranching treatment (PDS). DAS and PDS were then hydrolyzed by ${\alpha}-amylase$ and amyloglucosidase to obtain DAS.H and PDS.H. Differences in structural characteristics and in vitro digestibility among the four samples were investigated. The results showed that granules of RS had a rough surface and irregular shape. DAS had the lowest amylose content (29.52%), whereas PDS.H had the highest amylose content (41.96%). The order of crystallinity of the RS was: PDS.H (31.23%) > DAS.H (30.16%) > PDS (21.23%) > DAS (15.30%). Analysis by in vitro digestibility indicated a decreased hydrolysis index and glycemic index due to lower swelling power and water-binding capacity, and a well-ordered double helix structure and more crystallization in PDS.H than in the other RS samples. These results suggest that pullulanase debranching combined with ${\alpha}-amylase$ and amyloglucosidase hydrolysis may produce better RS with improved crystalline structure and higher digestion resistibility.

ON THE INTERACTION BETWEEN THE OF BORDER-FREE SCIENCE AND THE NATIONAL CONSCIOUSNESS

Li Tao,Chen Suping 한국환경보건학회 2001 한국환경보건학회 학술대회 자료집 Vol.2001 No.-

Classification of Pathological Voice Using Artigicial Neural Network with Normalized Parameters

Li, Tao,Bak, II-suh,Jo, Cheolwoo 한국음성과학회 2004 음성과학 Vol.11 No.1

In this paper we examined the effect of normalization on discriminating the pathological voice into normal and abnormal classes using artificial neural network. Average values per each parameter were used to normalize each set of parameter values. Artificial neural networks were used as classifiers. And the effect of normalization was evaluated by comparing the discrimination results between original and normalized parameter sets.

毛宗岗《三国演义》评点中的诗性结构观研究

李?(Li Tao) 동아인문학회 2019 동아인문학 Vol.47 No.-

With regard to the structural problems of Chinese Ming and Qing Dynasties" novels, under the influence of Western causal traditions and their structural views, there has always been a saying of “episodic”. However, if we take the traditional Chinese view of nature, we can see the poetic structure of Chinese classical novels. Mao Zonggang revealed this in the practice of the commentary of The Romance of the Three Kingdoms. He commented on the external structure of the Romance of the Three Kingdoms and conveyed the concept of its historical cycle with a “circular” structure; And he sorted out the sub-structure chapters of The Romance of the Three Kingdoms by adopting a repetitive(反复), uplifting (起兴), dualistic(对偶) and other poetic way to pinpoint the ideals of Confucian politics. This paper believes that Mao Zonggang"s commentary on the structure of The Romance of the Three Kingdoms reflects a poetic structure that is different from the West. This kind of poetic structure takes the classical tradition of Chinese literary narrative, and combines lyrics with historical narratives to form a new tradition. The “weaving” of structure takes on the dual mission of “Zhu”(杼) and “Xu”(序), making the narrative of chinese classical literature combines the tradition of “Shi Yan Zhi”(诗言志) and the tradition of “Wen Yi Zai Dao”(文以载道) through the poetic structure, forming the national style of “singing story”.

Antifungal Activity and Action Mode of Pinocembrin from Propolis against Penicillium italicum

Litao Peng,Shuzhen Yang,Yunjiang Cheng,Feng Chen,Siyi Pan,Gang Fan 한국식품과학회 2012 Food Science and Biotechnology Vol.21 No.6

The antifungal activity and possible mode of action of pinocembrin isolated from propolis against Penicillium italicum were investigated. Pinocembrin exhibited strong antifungal activity against P. italicum in a dosedependent manner. Respiration rates of P. italicum during spore germination and mycelial growth were significantly inhibited when exposure to pinocembrin. The respirations of mitochondria in state 2 and state 3 from mycelia were significantly inhibited in the presence of this compound. The phosphorylated adenosine nucleotides levels in hyphae of P. italicum treated with pinocembrin were significantly low and energy charge value became unstable. Unltrastructure of hyphae was seriously damaged with pinocembrin incubation for 24 h, which was further confirmed by the increase of relative ionic leakage and soluble protein loss of P. italicum mycelia treated with pinocembrin. It was concluded that pinocembrin inhibited the mycelial growth of P. italicum by interfering energy homeostasis and cell membrane damage of the pathogen. Pinocembrin would be a promising bioactive compound for treatment of P. italicum infections on postharvest citrus fruit.

Potassium Humate-Derived Nitrogen-Doped Activated Carbons with Narrow Micropore Size Distribution for High-Performance Supercapacitors

Lingli Xie,Litao Kang,Yae Li,Mangwei Cui,Bo Chang,Haiwei Jiang,Lili Gao,Xiaomin Wang,Shan Yun 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2017 NANO Vol.12 No.4

Micro-porous activated carbons (ACs) with a narrow pore size distribution of 0.4–0.6 nm and high specific surface areas (1160–1315 m2 · g-1) are prepared from environment-friendly, lowgrade potassium humate (HA-K, carbon resource) and mild activating agent potassium acetate (CH3COOK). Microstructure characterizations indicate that the introduction of activating agent CH3COOK is a key step to achieve high specific surface area and carbonization degree. These ACs contain small amount of oxygen and nitrogen, and show obvious pseudo-capacitance besides double layer capacitance. As a result, the optimized ACs achieve high specific capacitances of 311 F · g-1 and 317 F · g-1 at 0.1 A · g-1 in 2 M KOH and 1 M H2SO4 aqueous electrolytes, respectively. This sample also shows a good charge-discharge cycling stability within 10 000 cycles.

Control of Citrus Green and Blue Molds by Chinese Propolis

Shuzhen Yang,Litao Peng,Yunjiang Cheng,Siyi Pan,Feng Chen 한국식품과학회 2010 Food Science and Biotechnology Vol.19 No.5

Green and blue molds, caused by Penicillium digitatum and Penicillium italicum, respectively, are economically important postharvest diseases of citrus fruits. In this study, Chinese propolis ethyl acetate extract (PEAE) was evaluated to control P. digitatum and P. italicum on postharvest citrus fruits. The results indicated PEAE strongly inhibited mycelia growth and induced hyphae prominent abnormal morphological alterations. Also, PEAE had strong detrimental effect on spore germination of the tested pathogens in a concentrationdependent manner. For in vivo tests, PEAE could both reduce decay caused by P. digitatum and P. italicum respectively in wound-inoculated fruit and naturally infected fruit; meanwhile, no negative influences on the overall quality of the citrus fruits were observed with PEAE treatment. Therefore, PEAE could be used as a natural antifungal agent to control citrus blue and green mold.