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Three species of the family Noctuidae (Lepidoptera) new to China
Hui-Lin HAN,Zhao-Yao DUAN,Zhi-Wei FENG2 한국곤충학회 2008 Entomological Research Vol.38 No.3
Three species of the family Noctuidae –- Phlogophora striatovirens (Moore, 1867), Usbeca kulmburgi (Rebel, 1918) and Feliniopsis leucostigma (Moore, 1867) –- are reported for the first time from China. Photographs of adults and genital characteristics are provided.
Feng-Jie Lin,Xian-Dong Lin,Lu-Ying Xu,Shi-Quan Zhu 한국분자세포생물학회 2020 Molecules and cells Vol.43 No.10
To elucidate the mechanism of action of HOXA11-AS in modulating the cisplatin resistance of nasopharyngeal carcinoma (NPC) cells. HOXA11-AS and miR-454-3p expression in NPC tissue and cisplatin-resistant NPC cells were measured via quantitative reverse transcriptase polymerase chain reaction. NPC parental cells (C666-1 and HNE1) and cisplatin-resistant cells (C666-1/DDP and HNE1/DDP) were transfected and divided into different groups, after which the MTT method was used to determine the inhibitory concentration 50 (IC50) of cells treated with different concentrations of cisplatin. Additionally, a clone formation assay, flow cytometry and Western blotting were used to detect DDP-induced changes. Thereafter, xenograft mouse models were constructed to verify the in vitro results. Obviously elevated HOXA11-AS and reduced miR-454-3p were found in NPC tissue and cisplatin-resistant NPC cells. Compared to the control cells, cells in the si-HOXA11-AS group showed sharp decreases in cell viability and IC50, and these results were reversed in the miR-454-3p inhibitor group. Furthermore, HOXA11-AS targeted miR-454-3p, which further targeted c-Met. In comparison with cells in the control group, HNE1/DDP and C666-1/DDP cells in the si-HOXA11-AS group demonstrated fewer colonies, with an increase in the apoptotic rate, while the expression levels of c-Met, p-Akt/Akt and p-mTOR/mTOR decreased. Moreover, the si-HOXA11-AS-induced enhancement in sensitivity to cisplatin was abolished by miR-454-3p inhibitor transfection. The in vivo experiment showed that DDP in combination with si-HOXA11-AS treatment could inhibit the growth of xenograft tumors. Silencing HOXA11-AS can inhibit the c-Met/AKT/mTOR pathway by specifically upregulating miR-454-3p, thus promoting cell apoptosis and enhancing the sensitivity of cisplatin-resistant NPC cells to cisplatin.
Feng Lin,Wenming Jiang 한국원자력학회 2018 Nuclear Engineering and Technology Vol.50 No.8
Nuclear-related facilities can be detrimentally affected by ground vibrations due to the collapse ofadjacent cooling towers in nuclear power plants. To reduce this hazard risk, a design-oriented accelerationresponse spectrum (ARS) was proposed to predict the dynamic responses of nuclear-related facilitiessubjected to ground vibrations. For this purpose, 20 computational cases were performed basedon cooling tower-soil numerical models developed in previous studies. This resulted in about 2664ground vibration records to build a basic database and five complementary databases with considerationof primary factors that influence ground vibrations. Afterwards, these databases were applied to generatethe design-oriented ARS using a response spectrum analysis approach. The proposed design-orientedARS covers a wide range of natural periods up to 6 s and consists of an ascending portion, a plateau,and two connected descending portions. Spectral parameters were formulated based on statisticalanalysis. The spectrum was verified by comparing the representative acceleration magnitudes obtainedfrom the design-oriented ARS with those from computational cases using cooling tower-soil numericalmodels with reasonable consistency.
Feng Lin,Hongzhi Li 한국원자력학회 2017 Nuclear Engineering and Technology Vol.49 No.5
Nuclear power plants under expansion and under construction in China are mostly located in coastal areas, which means they are at risk of suffering strong earthquakes and subsequent tsunamis. This paper presents a safety analysis for a new reinforced concrete containment vessel in such events. A finite element method-based model was built, verified, and first used to understand the seismic performance of the containment vessel under earthquakes with increased intensities. Then, the model was used to assess the safety performance of the containment vessel subject to an earthquake with peak ground acceleration (PGA) of 0.56g and subsequent tsunamis with increased inundation depths, similar to the 2011 Great East earthquake and tsunami in Japan. Results indicated that the containment vessel reached Limit State I (concrete cracking) and Limit State II (concrete crushing) when the PGAs were in a range of 0.8-1.1g and 1.2-1.7g, respectively. The containment vessel reached Limit State I with a tsunami inundation depth of 10 m after suffering an earthquake with a PGA of 0.56g. A site-specific hazard assessment was conducted to consider the likelihood of tsunami sources.
New Aconitine-Type C19-Diterpenoid Alkaloids from Aconitum hemsleyanium var. circinacum
Feng Gao,Dong-Lin Chen,Feng-Peng Wang 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.12
Two new aconitine-type C19-diterpenoid alkaloids, hemsleyanines C (1) and D (2), were isolated from the roots of Aconitum hemsleyanium var. circinacum, their structures were determined by the chemical evidence and spectral analyses.
Lin, Feng,Wu, Xiaobao Korea Concrete Institute 2016 International Journal of Concrete Structures and M Vol.10 No.4
Experimental studies were conducted on 36 grouted splices to investigate their mechanical performance under four loading schemes: (1) incremental tensile loading, (2) repeated tensile loading, (3) cyclic loading at high stress, and (4) cyclic loading at large strain. Load-deformation responses of the grouted splices under cyclic loadings were featured with pinching effect and stiffness degradation compared to those responses under tensile loadings. The shape of the hysteresis loops of load-deformation curves was similar to that under incremental tensile loading. For the purpose of structural analysis, stress-strain relationships were presented for grouted splices under various loadings.
Lin Xiong,Ya-Qin Gao,Wei-Hong Li,Tian-Feng Guo,Xiao-Lin Yang 한국식품과학회 2015 Food Science and Biotechnology Vol.24 No.5
An LC-MS/MS method was established for simultaneous identification of levels of bilpaterol, cimbuterol, clenproperol, and bambuterol in goat and beef muscle. Meat samples were subjected to extraction using an aqueous acidic solution and cleansed using MCX solid phase extraction. β2-Agonists residues were extracted using an aqueous acidic solution. Proteins in extraction liquids was removed based on adjusting pH using perchloric acid and a sodium hydroxide solution, followed by SPE for clean-up. Linearity values of the method based on R2 values were 0.9976-0.9997 with 70.1-108.8% recovery and relative standard deviation values of 3.5-13.3%. Low limits of detection (LOD) and quantitation (LOQ) of 0.01-0.02 and 0.02-0.08 μg/kg, respectively, were achieved for spiked goat and spiked beef muscle. The method was sensitive and specific and is an improvement over other currently available technologies.
Feng, Zhi-Qiang,Yang, Xiao-Li,Ye, Yuan-Feng,Hao, Lin-Yun Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.4
The design, synthesis, and structural characterization of two new palladium complexes based on Schiff base ligands is reported; $[Pd(L1)_2]$ (1) and $[Pd(L2)_2]$ (2), [HL1 = 2-((E)-(2,6-diethylphenylimino)methyl)-4,6-dibromophenol, L2 = (E)-N-benzylidene-2,6-diethylbenzenamine], which are obtained by functionalizing Schiff base ligands with or without electron-withdrawing groups. Both compounds are mononuclear structures. Comparisons are made to the compounds 1 and 2 to analyze and understand the effect of electron-withdrawing groups. Antibacterial activity studies indicate the electron-withdrawing groups on Schiff base ligands enhance antibacterial activity. Catalytic activity, however, is reduced due to the enhanced steric-hindrance of the electron-withdrawing groups. Electronic absorption and emission properties of HL1, L2, 1 and 2 are also reported.
Streptomyces Telomeres Contain a Promoter
Lin, Yuh-ru,Hahn, Mi-Young,Roe, Jung-Hye,Huang, Tzu-Wen,Tsai, Hsiu-Hui,Lin, Yung-Feng,Su, Tsung-Sheng,Chan, Yu-Jiun,Chen, Carton W. American Society for Microbiology 2009 Journal of Bacteriology Vol.191 No.3
<B>ABSTRACT</B><P>Bidirectional replication of the linear chromosomes and plasmids of <I>Streptomyces</I> spp. results in single-strand overhangs at their 3′ ends, which contain extensive complex palindromic sequences. The overhangs are believed to be patched by DNA synthesis primed by a terminal protein that remains covalently bound to the 5′ ends of the telomeres. We discovered that in vitro a conserved 167-bp telomere DNA binds strongly to RNA polymerase holoenzyme and exhibits promoter activities stronger than those of an rRNA operon. In vivo, the telomere DNA exhibited promoter activity in both orientations on a circular plasmid in <I>Streptomyces</I>. The telomere promoter is also active on a linear plasmid during exponential growth. Such promoter activity in a telomere has not hitherto been observed in eukaryotic or prokaryotic replicons. <I>Streptomyces</I> telomere promoters may be involved in priming the terminal Okazaki fragment (during replication) replicative transfer (during conjugation), or expression of downstream genes (including a conserved <I>ttrA</I> helicase-like gene involved in conjugal transfer). Interestingly, the <I>Streptomyces</I> telomeres also function as a promoter in <I>Escherichia coli</I> and as a transcription enhancer in yeast.</P>