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Le-Le Shao,Jia-Min Zhou,Qing Zhu,Xiao-Ling Wang,Robert C. Hider,Tao Zhou 한국식품과학회 2019 Food Science and Biotechnology Vol.28 No.4
Melanosis developed in shrimp (Penaeus vannamei)is mainly initiated by polyphenoloxidase (PPO),thus understanding of the characteristics of PPO in shrimpis important for controlling the melanosis of shrimp. Theshrimp cephalothorax turns black most rapidly amongst allthe tissues during the chilled storage. Crude PPO extractedfrom this cephalothorax has an optimal pH of 6.0 and anoptimal temperature of 50 C. PPO is relatively stable underneutral and weak alkaline conditions (pH 5.5–9.0) andthe temperature range of 25–35 C. The kinetic parametersKm and Vmax were recorded as 3.02 mM and 54.3 U/mg ofprotein, respectively, using L-Dopa as a substrate. Themolecular weight of PPO was estimated as 200–220 kDaby an activity staining test. A hydroxypyridinone derivative,5-hydroxy-1-octyl-4-oxo-1,4-dihydropyridine-2-carbaldehydeO-ethyl oxime, was demonstrated to efficientlyinhibit the PPO, indicating that this compound might findapplication as a shrimp preservative.
Yuan Tao,문철주(Mun Cheilju),Tang Le 영남대학교 중국연구센터 2020 중국과 중국학 Vol.- No.39
서비스 무역은 전 세계 경제 발전의 새로운 원동력이 되었으며, 그 중에서도 금융서비스 무역은 고도성장을 이루었다. 금융서비스무역의 경쟁률 높이는 것은 각국의 관심사가 되었다. 따라서 본 연구는 세계 43개 국가와 지역의 2000년∼2017년의 패널 데이터를 사용하여 금융개방이 금융서비스 무역경쟁력에 미치는 영향요인을 실증분석 연구를 통해서 밝히고자 한다. 연구결과를 보면 전체적인 수치에서나 선진국가과 개발도상국가 및 지역의 패널 데이터에서 보면 금융개방이 금융서비스 무역경쟁력과 현저히 관련이 있음을 알 수 있다. 또한 선진경제권의 금융서비스무역경쟁력 제고는 금융개방에 따른 충격을 견딜 수 있고, 금융개방과 금융서비스 경쟁력제고는 정의 상관관계를 나타났다. 그러나 일부 학자들은 개발도상국가의 경제충격에 대한 제한으로 금융개방과 금융서비스무역 경쟁력 제고 간의 꼭 정의 상관관계가 아닐 수 있다는 견해도 있다. 그러나 본 연구에서는 개발도상국의 금융개방과 금융서비스경쟁력과 현저히 정의 상관관계가 있는 것으로 나타났다. 이는 중국 등 개발도상국의 금융개방의 귀감이 될 수 있다. Service trade has now become a new driving force for economic development around the world, in which financial services trade has achieved rapid growth, and improving the competitiveness of financial services trade has also become a concern of all countries. This thesis uses panel data of 43 countries and regions from 2000 to 2017 to conduct empirical research on the impact of financial liberalization on the competitiveness of financial services trade. Both the empirical results of overall data and the panel data of developed and developing countries and regions show that financial liberalization has a significant positive influence on the competitiveness of financial services trade. Some scholars believe that the financial services trade of developed economies is highly competitive and can withstand the impact of financial openness, so financial openness of developed economies is significantly positively related to the competitiveness of financial services trade, but the ability of developing countries to withstand shocks is limited, and the relationship between service trade competitiveness and financial openness of developing countries is not necessarily positively. The research in this paper shows that there is significant positive correlation between the financial opening of developing countries and the competitiveness of financial services trade, which is of reference for the financial opening of developing countries such as China.
S100A14 Promotes the Growth and Metastasis of Hepatocellular Carcinoma
Zhao, Fu-Tao,Jia, Zhan-Sheng,Yang, Qun,Song, Le,Jiang, Xiao-Jing Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.6
Background: S100A14 has recently been implicated in the progress of several types of cancers. This study aimed to investigate the clinical significance and possible mechanisms of action of S100A14 in the invasion and metastasis of hepatocellular carcinoma (HCC). Methods: S100A14 expression in HCC was detected at mRNA and protein levels and its prognostic significance was assessed. Functional roles of S100A14 in HCC were investigated using MTT, BrdU, wound healing, transwell invasion assay and HCC metastatic mouse model. Results: S100A14 was significantly elevated in HCC tissues, correlated with multiple tumor nodes, high Edmondson-Steiner grade and vascular invasion. Multivariate Cox analysis showed that the S100A14 expression level was a significant and independent prognostic factor for overall survival (OS) of HCC patients (hazard ratio=1.98, 95% confidence interval=1.14-3.46, P=0.013). S100A14 promoted cell proliferation, invasion and metastasis of HCC in vitro and in vivo. Conclusion: These results suggest S100A14 is a novel prognostic marker and therapeutic target for HCC.
Three New Oleanane-Type Triterpene Saponins from Gladiolus gandavensis
Tai, Zhi-Gang,Cai, Le,Yang, Ya-Bin,Liu, Chuan-Shui,Xia, Jian-Jun,Ding, Zhong-Tao Korean Chemical Society 2010 Bulletin of the Korean Chemical Society Vol.31 No.10
Three new oleanane-type triterpene saponins (1, 2 and 3) were isolated from aerial parts of Gladiolus gandavensis, along with two known compounds (4 and 5). Their structures were elucidated as 29-O-($\beta$-D-glucopyranosyl)-$2{\beta}$,$3{\beta}$-dihydroxyolean-12-en-28-oicacid(1), 3-O-($\beta$-D-xylopyranosyl)-29-O-($\beta$-D-glucopyranosyl)-12-en-28-oic acid (2), and $2{\beta}$,$3{\beta}$,29-trihydroxyolean-12-en-28-oic acid 28-O-[$\beta$-D-glucopyranosyl($1{\rightarrow}2$)-($\alpha$-L-rhamnopyranosyl($1{\rightarrow}6$))-$\beta$-D-glucopyranosyl] ester (3), by spectroscopic methods, and by comparison with known analogues. These oleanane-type triterpene saponins glycosidated at C-29 were not obtained frequently.
Three New Oleanane-Type Triterpene Saponins from Gladiolus gandavensis
Zhi-Gang Tai,Le Cai,Ya-Bin Yang,Chuan-Shui Liu,Jian-Jun Xia,Zhong-Tao Ding 대한화학회 2010 Bulletin of the Korean Chemical Society Vol.31 No.10
Three new oleanane-type triterpene saponins (1, 2 and 3) were isolated from aerial parts of Gladiolus gandavensis,along with two known compounds (4 and 5). Their structures were elucidated as 29-O-(β-D-glucopyranosyl)-2β,3β-dihydroxyolean-12-en-28-oicacid(1), 3-O-(β-D-xylopyranosyl)-29-O-(β-D-glucopyranosyl)-12-en-28-oic acid (2),and 2β,3β,29-trihydroxyolean-12-en-28-oic acid 28-O-[β-D-glucopyranosyl(1→2)-(α-L-rhamnopyranosyl(1→6))-β-D-glucopyranosyl] ester (3), by spectroscopic methods, and by comparison with known analogues. These oleanane-type triterpene saponins glycosidated at C-29 were not obtained frequently.
Qi Sun,Jianmei Li,Tao Le,Lei Zhang 대한화학회 2018 Bulletin of the Korean Chemical Society Vol.39 No.5
Herein, a facile and enzyme?free CP sensor was fabricated by in situ electrochemical reduction strategy on the surface of glassy carbon electrode (GCE). Reduced graphene oxide (RGO) was chose as supporting materials for the distribution of platinum nanoparticles (Pt NPs) to obtain improved catalytic properties. The applicability and suitability of the obtained RGO?Pt/GCE for 4?CP detection were also evaluated. The results indicated that the RGO?Pt NPs modified electrode displayed much better catalysis and higher sensitivity for 4?CP oxidation. Under optimum conditions, the oxidation peak current was proportional to 4?CP concentration in the range from 0.1 to 500??M with a detection limit of 51?nM. Meanwhile, it is demonstrated that the prepared sensor is also characterized by excellent feasibility, satisfactory reproducibility, good stability and high specificity. The results suggested that RGO?Pt/GCE could be a facile, cost?effective, and rapid tool for the prospect on?line evaluation of 4?CP in drinking water samples.
Jian-Wei Dong,Le Cai,Xue-Jiao Li,Jia-Peng Wang,Rui-Feng Mei,Zhong-Tao Ding 대한약학회 2017 Archives of Pharmacal Research Vol.40 No.12
Three new monoterpene phenylpropionic acidesters, illigerates A–C (1–3), and one new aporphinealkaloid, illigeranine (4), as well as four known ones,actinodaphnine (5), nordicentrine (6), 8-hydroxy carvacrol(7), and 3-hydroxy-a,4-dimethyl styrene (8), were isolatedfrom the tubers of Illigera aromatica. The structures of 1–4were identified by HRESIMS, 1D and 2D NMR, andelectronic circular dichroism spectra. Compound 1 potentlyinhibited NO production in LPS-stimulated RAW264.7cells with an IC50 value of 18.71 ± 0.85 lM; compound 1,3, and 4 showed moderate butyrylcholinesterase inhibitoryactivities with the IC50 values of 46.86 ± 0.65,53.51 ± 0.71, and 31.62 ± 1.15 lM, respectively. Compound4 showed weak AChE inhibitory activity with anIC50 value of 81.69 ± 2.07 lM, and compounds 5 and 6possessed moderate AChE inhibitory activities with theIC50 values of 47.74 ± 1.66 and 40.28 ± 2.73 lM,respectively. This paper provides a chemical structure andbioactive foundation for using I. aromatica as an herbalmedicine.
Childhood Obesity Is a High-risk Factor for Hypertriglyceridemia: A Case-control Study in Vietnam
Nguyen Thi Hong Hanh,Le Thi Tuyet,Duong Thi Anh Dao,Yang Tao,Dinh-Toi Chu 질병관리본부 2017 Osong Public Health and Research Persptectives Vol.8 No.2
Objectives: To investigate the relationship between dyslipidemia and obesity status among Vietnamese adolescents. Methods: In this case-control study, 282 adolescents (6–11 years), including 88 obese cases and 194 normal-weight controls, were recruited from a population-based cross-sectional study from two provinces in Vietnam. The anthropometric, blood lipid, and other laboratory test results of the study subjects were analyzed. Results: Obese children tended to have more visceral fat (Pearson’s r = 0.795, p < 0.0001) than subcutaneous fat (Pearson’s r = 0.754, p < 0.0001), and this difference was associated with an increase in blood triglyceride level (Pearson’s r = 0.232, p < 0.05) and a strikingly high rate of hypertriglyceridemia (38.6%). We also found that birth weight and parental body mass index were related to the status of obesity among the study subjects. However, only birth weight was significantly higher in the obese group than in the normal weight group. These findings indicate the effect of prenatal nutrition on childhood obesity. Furthermore, high-birth weight children had a surprisingly high rate of obesity. Conclusion: Together, our data suggest that obesity increased the risk for hypertriglyceridemia, which was, at least partially, due to prenatal nutrition.