장이간 이뇨제 남용중인 특발성 또는 자가획득 부종간의 병태생리의 차이

민경환(Kyung Hwan Min),김호중(Ho Jung Kim),유준호(Jun Ho Ryu),한상웅(Sang Woong Han),강석우(Seok Woo Kang),문중돈(Jung Don Mun) 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.1

N/A Patients suffering from idiopathic or self-induced edema are uniformly characterized by chronic use of furosemide, which leads to vicious cycle of edema. Among chronic furosemide users who don't have any other specific edema forming diseases, 9 patients from the outpatient clinic(OC) and 6 patients examined at the emergency room(ER) used it mainly for weight reduction and for cyclical edema, respectively. All of the ER group patients were presented with severe hypokalemia(2.04±0.2mEq/L; range 1.3 to 2.7 mEq/L) and alkalosis(748±0.01; range 7.44 to 7.51) but none from the OC group showed such results. Other baseline parameters including Plasma renin activity(PRA) and aldosterone level on recumbency, and FEn₂were similar in both groups. In contrast, daily working hours(6.1±0.5 vs 10±0.6hr, p<0.01), average body weight gain between AM and PM(0.4±0.1 vs 0.9±0.lkg, p<0.01), peak weight gain interval(9±0.8 vs 5±0.1day, p<0.05), PRA(7.6±1.5 vs 23.5±7.2ng/ml/h, p<0.05) and aldosterone level(22.1±4.2 vs 64.8±10.4 ng/dl, p<0.01) on ambulation, and FEk. on normokalemia(ll±2A vs 36±7.7%, p<0.01) were statistically different between the two groups. In comparison to the OC group, both the amout of urine(617±39 vs 358±26ml, p<0.01) and the percent change of PRA(-14±4 vs -3±2%, p<0.05) and al-dosterone level(-17±5 vs -4±3%, p<0.05) after saline loading(lL over 1hr, IV) following ambulation were smaller in the Elt group. Moat of the ER group patients(5/6) required aldosterone antagonist (spironolactone) added to K(+) supplement, but all of the OC group patients were managed to maintain an edema-free status with conservative treatment. In conclusion, patients with idiopathic edema seem to have more fluid transudation out of intravascular space during orthostasis with a prominent degree of deranged renin-aldosterone axis and K(+) metabolism than those with self-induced edema.

쇄목펄프폐수를 이용한 Bacillus thuringiensis var. israelensis의 Spore-Crystal 복합체 생산에 관하여

김영돈,김태전,윤경하 순천향대학교 1991 논문집 Vol.14 No.3

쇄목펄프공정폐수를 이용하여 상품균주인 Bacillus thuringiensis var. israelensis (Comm. B.t.i)와 serotype H-14인 Bacillus thuringiensis var. israelensis(Serotype B.t.i)의 spore-crystal복합체 생산성과 폐수의 BOD 감소량을 조사하였다. 펄프폐수에 Peptone 1.0%, K₂HPO₄ 0.05%, MgSO₄ㆍ7H₂O 0.01% 및 CaCl₂0.02% 등을 첨가하여 균주를 30℃에서 200rpm 으로 진탕배양했을때 Comm. B.t.i는 배양40시간에, Serotype B.t.i는 배양 32시간에 최대 생장을 나타냈다. 배양 72시간에 생성된 아포 수는 Comm. B.t.i는 8.3 ×?? spores/ml, Serotype B.t.i는 6.4 x ?? spores/ml였고, 폐수의 BOD는 71-72%의 감소를 나타냈다. 두 균주가 생성한 spore-crystal복합체의 농도가 ?? spores/ml 일때 Culex pipens 유충은 12시간내에 100% 치사되었다. Effect of some nutrient on the growth of Bacillus thuringiensis var.israelensis in the ground wood pulp will waste liquor was determined during an attempt to lower the BOD content of the waste liquor and to produce spore-crystal complex by bacteria. The stain applied were commercial Bacillus thuringiensis var. israelensis (Comm. B.t.i) and serotype H-14, Bacillus thuringiensis var. israelensis(Serotype B.t.i), The necessity of the addition of 1.0% pep-tone, 0.05% K₂HPO₄, 0.01% MgSO₄7H₂O and 0.02% CaCl₂for the best growth of two strains in the waste liquor was ascertained as a result. Comm. B.t.i was at a maximal growth after the 40 hour of incubation but Serotype B.t.i, after the 32 hour of incubation of the strains in the supplemental waste liquor, spore count of Comm. B.t.i and Serotype B.t.i were 8.3 x ?? spores/ml and 6.4 x ?? spores/ml respectively and the BOD content of the waste liquor was lowered by about 70%. Two strains showed 100% of lethal rate, when Culex pipiens larvae were exposed to ?? spores/ml of concentration of spore-crystal complex.

쇄목펄프폐수를 이용한 Bacillus thuringiensis var. israelensis 의 Spore-Crystal 복합체 생산에 관하여

윤경하,김영돈,김태전 서울保健大學 1991 論文集 Vol.11 No.1

기준물을 이용한 NC 공작기계의 오차규명 및 보상제어

김경돈,정성종 韓國工作機械學會 2000 한국생산제조학회지 Vol.9 No.2

Methodology of volumetric error identification and compensation is presented to improve the accuracy of NC machine tools by using a reference artifact and a touch trigger probe. Homogeneous transformation matrix and kinematic chain are used for modeling the geo-metric and thermal errors of a three-axis vertical machining center. The reference artifact is designed and fabricated to identify the model parameters by machine tool metrology. Parameters in the error model are able to be identified and updated by direct measurement of the reference artifact on the machine tool under the actual conditions which include the thermal interactions of error sources. A volumetric error compensation system based on IBM/PC is linked with a FANUC CNC controller to compensate for the identified volumetric error in machining workspace.

고정밀 금형의 쾌속제작을 위한 CAD/CAM/CAI 기술

김경돈,정성종 韓國工作機械學會 2000 한국생산제조학회지 Vol.9 No.3

근대문학의 이념과 문학의 관습 : 「文學이란 何오」와 『朝鮮의 文學』을 중심으로

이경돈 민족문학사학회 2004 민족문학사연구 Vol.26 No.-

이광수의 「문학이란 하오」이래 문학은 'Literature'의 번역어에 한정되었다. 전대의 문학적 유산과의 전면적 단절을 요구한 이광수의 '문학'은, 새로운 어의의 창출이었고 과거의 민족사적 경험을 통해서는 증명할 수 없었던 이념이었다. 이광수의 '문학'은 과거의 경험과 단절함으로써 문학사의 구성에 난감할 수밖에 없었다. 이광수가 상상한 '문학'이라는 이념은 역사를 갖지 못하고 다만 근대에의 희구와 함께 자가 증식하며 저변을 확보했던 것이다. 그러나 같은 시기 문학을 상상하는 다른 방법이 공존하고 있었다. 안확의 『조선의 문학』, 『조선문학사』가 그것이다. 안확도 이광수와 유사한 근대문학의 개념을 제시했지만, 그 범주는 시대구분론, 순/잡문학 이분론 등을 통해 문학의 변천과 차이를 포괄할 수 있었다. 안확의 문학 개념은 문학사를 서술하기 위한, 즉 근대문학의 이념을 더욱 확장하기 위한 것이었지만, 결과적으로 근대문학의 형성기 전혀 다른 문학을 상상하는 방법이 있었음을 드러내는 증좌라 할 수 있다. 근대문학에 대한 다양한 상상이 가능했음을 염두에 둘 때, '문학'이 'Literature'로 확정되면서 잃어버렸던 다양한 '문학' 외(外) 문학, '문학' 전(前) 문학도 다시 생명을 얻게 된다. 이들은 'Literature'가 아닌 문학이며, 문학의 관습을 이어온 또 하나의 문학인 것이다. Formation of our modern Literature was the progress of excluding and abolishing not a little heritages which had much literary possibilities. Literature had much changes and thus did away with traditional literature. Also according to applying to modern literature looked coldly upon new coming possibilities. To Lee Kwang-su and Bak dae-jin in the 1910s who studied abroad, literature meaned only literature which came through Japan and already conceptualized in western countries. So they had exclusive features. But An Hwak remade history of literature and included literary extension. Like this there were many ways to imagine literature in the modern period of enlightenment. It seemed to coexist concept of extensive literature including essays and mean works. Traditional literature was pushed out of the literary range. That is one of the possibility and custom of korean literature.

CO₂레이저빔에 의한 이종재질 및 이종두께의 Tailored Blank 용접에 관한 연구

이경돈,유병길,김도훈,황창선 한국레이저가공학회 1999 한국레이저가공학회지 Vol.2 No.3

This research was conducted as a fundamental study to apply tailored blank welding technique into automotive production process. The materials used in this study were 2.0mm thickness low carbon steel sheets and 1.2mm Zn-coated low carbon steel sheets. To ensure the reproducibility and to consider various factors, experiments were conducted by applying Taguchi experimental method with 6 factors. Every welding process was repeated 3 times to offset the effect of uncontrolled factors. Elongation and LDH(Limited Dome Height) were measured to evaluate formability of specimens and Optical microscopy, XRD, SEM, and EDS analysis were performed to observe the microstructures and to determine the solidification mode in the weld. The elongation of specimen welded with optimum condition was 83% of base metal, and LDH was 84% of base metal. In case of laser treated specimen where Zn coating was removed, elongation was 85% of base metal, and LDH was 85% of base metal. In fusion zone, phases were consisted of quasi-polygonal ferrite, banitic ferrite, and martensite.

반복작업으로 유발된 수근관내의 굴곡근 건초염과 수근관 증후군 : 증례 보고 Case Report

김돈규,서경묵,신주연,강시현,송인섭 중앙대학교 의과대학 의과학연구소 2003 中央醫大誌 Vol.28 No.1

A 46 year-old woman who had worked repetitive manual job for 3 years visited our hospital because of aggravated right hand sensory symptom and newly developed limitation of 3, 4, 5th finger extension. In physical examination, moderate swelling of volar aspect of wrist and limitation of finger extension was noticed as well as positive tinnel sign. We confirmed carpal tunnel syndrome after electrodiagnostic studies and associated flexor tenosynovitis of 4th flexor tendon in the carpal tunnel through MRI (magnetic resonance imaging) study. She was successfully treated with conservative program including wrist splint and steroid injection. We also tracked the result of treatment using MRI and electrodiagnositic studies. Analyzing her work procedure, we concluded that repetitive and forceful exertional nature of job impose a high burden on hand and wrist region and it caused her carpal tunnel syndrome.

압착방법별 포도 착즙액의 품질특성

최희돈,김성수,김경탁,홍희도,김상희 한국식품영양학회 2002 韓國食品營養學會誌 Vol.15 No.3

캠벨과 거봉을 이용하여 여러 가지 압착방법에 따른 착즙액의 이화학적 및 관능적 특성을 조사하였다. 수율의 경우 캠벨, 거봉이 동일하게 냉압처리보다는 온압처리가, 온압처리에서도 낮은 온도보다는 높은 온도에서 수율이 높게 나타났으며, 또 온압 · 펙틴분해 병행처리가 각각 83.5% , 87.3%로 가장 높은 수율을 나타내었다. 또한 당도와 아미노테 질소도 열처리온도의 상승 및 압착방법의 병행에 의해 감소하는 것으로 나타났다. 적정산도는 캠밸과 거봉이 압착방법에 따라 각각 0.86 ~ 1.00%, 0.60 ~ 0.69%로 거봉에 비해 캠벨의 산도가 높았으며, 열처리온도가 산도 증감에 더 큰 영향을 미치는 것으로 나타났다. 그리고 압착방법에 따른 착즙액에 대한 관능검사 결과 열처리 온도의 상승 및 착즙액에 대한 관능검사 결과 열처리온도의 상승 및 압착방법의 병행에 의해 떫은 맛과 산맛의 강도가 강하여지고 이들 처리구의 기호도가 높은 것으로 나타났다. The physicochemical and sensory properties of Campbell Early and Gerbong juices prepared by various pressing methods were studied. The yields of these juices by mixed method were 83.5% and 87.5%, the highest value of various pressing methods. And soluble solids and amino nitrogens of them decreased as heating temperature increased and was lowest when mixed method was performed. Titratable acidities of Campbell Early juice was 0.86 ~ 1.00%, higher than that of Gerbong juice, 0.60 ~ 0.69%. Also the strength of astringent taste and sour taste of Campbell Early and Gerbong juice increased as heating temperature increased, and increased strength of these tastes gave good sensory evaluation to grape juices.

유기용제 취급근로자들의 요중대사물질과 말초임파구 자매염색분체교환 발현빈도에 관한 조사연구

김돈균,황인경,류철인,이수일,정갑열,이용환,이충렬,현원일,김석봉,전용덕 大韓産業醫學會 1990 대한직업환경의학회지 Vol.2 No.1

저자들은 유기용제 취급여성근로자 90명을 대상으로 1988년 7월부터 1989년 8월까지 말초혈액임파구에서의 자매염색분체교환의 발현빈도를 조사하고 이들의 업종, 근속연수, 요중마뇨산 농도등이 자매염색분체교환의 발현빈도에 미치는 영향을 조사하였으며 그 결과를 요약하면 다음과 같다. 1. 유기용제 취급근로자들의 말초혈액임파구에서의 자매염색분체교환의 발현빈도는 대조군에 비하여 유의하게 증가되었다. 2. 말초혈액임파구에서의 자매염색분체교환의 발현빈도가 가장 높은 업종은 프라스틱제품 제조업이었다. 3. 근속연수가 말초혈액임파구에서의 자매염색분체교환의 발현빈도에 미치는 영향은 현저하지 않았다. 4. 요중마뇨산농도와 말초혈액임파구에서의 자매염색분체교환의 발현빈도간에는 유의한 상관관계가 있었다. In order to know the possibility of utilizing the sister chromatid exchanges as an index which could evaluate the effect of organic solvents on the health in industrial workers, the authors studied the effects of the inductivity of sister chromatid exchanges in peripheral lymphocytes from 90 female workers expoxed to organic solvents and 20 non-exposed female workers. The results obtained were as follows : 1. The frequency of sister chromatid exchanges in peripheral lymphocytes from 90 female workers exposed to organic solvents was significantly increased in comparison with 20 control subject. 2. The frequency of sister chromatid exchanges was significantly increased in the workers who were employed in the manufacture of plastic materials than the other manufactures. 3. There were no significant differences in the frequency of sister chromatid exchanges by carriers of the exposed workers.