위발성 위장관 악성림프종 환자에서 항암치료의 효과

김찬규,신영록,김현정,배상병,이남수,이규택,박성규,원종호,홍대식,박희숙 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

Purpose: The gastrointestinal (GI) tract is the most common site of extranodal non-Hodgkin's lymphoma (NHL), which is increasing in incidence, but there is no established optimal treatment modality. Thus, this study was investigated the clinicohistologic feature, the therapeutic modalities, and the prognosis for GI-NHL, as well as the factors affecting it. Methods: We retrospectively analyzed 45 patients who had been diagnosed as having GI-NHL and had been followed up from July 1994 to February 2005 at Soonchunhyang University Hospital. The patients were divided into groups according to the site of origin and to various other features, and the survivals of the various groups were compared. The modified Ann Arbor system and WHO classification were adopted for staging and histopathologic classification, respectively. Results: GI-NHL of the stomach, small bowel, ileocecal region, and colon occurred in 28 patients (62.2%), 5 patients (11.1%), 3 patients (6.7%), and 8 patients (17.8%), respectively, In one patient, the entire gastrointestinal tract was diffusely involved. The median age of patients was b5 years (25~78 years), and male-to-female ratio was 1:1.1. Fourteen patients were in stage Ⅰ, 24 in stage Ⅱ, 4 in stage Ⅲ, and 3 in stage Ⅳ. Surgical resection was performed in 19 patients, and combination chemotherapy was performed in 43 patients. Surgical resection only was performed in 4 patients, Chemotherapy only was performed in 26 patients. The expected overall 5 year survival of 45 patients was 39.6%, and there was a significant survival difference between the stages, but between sites of origin (p=0.842). The most important factors influencing the survival was the stage and other factors were not significant. Conclusion: The stomach was the most common site of GI-NHL. Most GI-NHL were localized Stage was the most important prognostic factor. However, Prospective randomized studies are needed to approve the therapeutic modality.

<기생충>에 드러난 자본과 공간 연구

조규찬(Cho Kyu―Chan) 한국비평문학회 2020 批評文學 Vol.- No.75

<기생충>은 21세기 자본주의 사회에서 자본의 소유 여부에 따라서 각각의 집단의 삶이 이루어지는 공간의 양상이 얼마나 달라질 수 있는지를 극명하게 보여준다. 개인이 소유한 자본의 양은 그들을 상위 또는 하위 집단이라는 차이를 강제적으로 구별하며, 이는 공간의 고착으로 이어질 수밖에 없다. 본고는 <기생충>을 통하여 드러나는 21세기 자본주의 사회의 문제점을 자본과 공간으로 인식하고, 등장 인물들에게 발생하는 구별 짓기를 통한 집단 간의 차이와 공간의 고착이 이루어지는 과정 및 집단 간 또는 집단 내 충돌이 비극적인 결말로 드러날 수밖에 없음을 살펴보았다. 먼저 <기생충>은 자본의 차이가 개인의 의지와는 관계없이 그들을 상위 또는 하위 집단으로 규정하며 위계적인 관계를 발생시킴을 보여준다. 하위 집단의 인물들은 상위 집단의 인물들과 위계적인 관계를 맺는 과정에서 생계를 연명하기 위하여 기생하는 선택을 할 수밖에 없다. 반면, 상위 집단의 인물들은 더 많은 자본을 바탕으로 하위 집단 인물들의 생계를 위협하며 자신들의 이익만 추구한다. 결국, 하위 집단의 인물들은 생계유지를 위하여 집단 내 충돌을 발생시키고, 그 과정에서 집단 간 충돌마저 망설이지 않는 모습을 드러낸다. <기생충>은 집단 내 또는 집단 간의 충돌을 비극적인 결말로 보여줌으로써 21세기 자본주의 사회가 직면한 자본과 공간의 문제점이 지닌 심각성에 관한 경종을 울린다는 점에서 의의를 지닌다. <Parasite> clearly shows how much the aspects of space in which each group’s lives take place can differ depending on the ownership of capital in the 21st century capitalistic society. The amount of capital owned by individuals forcibly distinguishes the difference of upper or lower groups, which inevitably results in the fixation of space. This paper acknowledges the problems of 21st capitalistic society as revealed in <Parasite> as that of capital and space, and examines how the differences in class through the categorization that applied to the characters, the process of how space becomes set in and the inter-groups or intra-group conflict can only meet with a tragic ending. Foremost, <Parasite> shows how the differences in capital define characters into either upper or lower group regardless of individual will and result in a hierarchical relationship. Characters in the lower group forms a hierarchical relationship with the characters in the upper group and must choose the life as parasites in order to keep living. On the contrary, the characters in the higher group threaten the lives of lower group characters with more capital and only pursue their interests. Ultimately, the characters of the lower group generate intra―group conflict in order to continue to make a living and in this process are not hesitant towards inter-group conflict. <Parasite> is significant because it rings the alarm on the significance of the problems of capital and space faced by 21st century capitalistic society by showing how intra-group or inter-group conflicts lead to tragic ending.

재발 또는 불응성 비호즈킨 림프종 환자에서 CDME 구제항암화학요법 후 고용량 항암화학요법 및 자가말초혈액 조혈모세포이식의 효과

김세형,한강원,배상병,김찬규,이남수,이규택,박성규,원종호,홍대식,박희숙 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.1

Background and objectives : The long-term survival in patients with non-Hodgkin's lymphoma (NHL) after conventional dose chemotherapy is about 35% and the rest of the patients tend to have relapse. So, in relapsed or refractory NHL, we compared the outcome of patients undergoing high-dose chemotherapy with autologous peripheral blood stem cell transplantation(APBSCT) with only salvage chemotherapy of cisplatin, dexamethasone, mitoxantrone, and etoposide(CDME). Materials and methods : From June 1993 to December 1999, 25 patients with relapsed or resistant NHL were treated with CDME regimen as salvage chemotherapy. Twelve patients were received four cycles of CDME chemotherapy, and 13 patients were received high-dose chemotherapy with APBSCT following two cycles of CDME chemotherapy. Results : The median follow-up duration was 12.8 months(range:4-68). The overall response rate was 41.7% (complete response rate 25%, partial response rate 16.7%) in 12 patients with CDME only. Thirteen patients who were treated with high-dose chemotherapy with APBSCT achieved 61.5% complete response rate and 15.4% partial response rate, with an overall response rate of 76.9%. The estimated 3-year progression-free survival rate was significantly higher among patients who received high-dose therapy than patients who received CDME only(41.5% vs 20.0%, p<0.05). And, 3-year overall survival rate was significantly higher among patients who received high-dose therapy(51.3% vs 25.0%, p <0.05). Conclusions : In relapsed or refractory NHL, CDME chemotherapy is an effective salvage chemotherapy and allow peripheral blood stem cell collection. Also, high-dose chemotherapy with APBSCT following CDME is superior to CDME salvage chemotherapy only.

흉선종 제거후에 발생한 재생 불량성 빈혈 : 증례보고

전원선,이상철,김현정,배상병,김찬규,이남수,박노진,이규택,박성규,홍대식,박희숙,원종호 순천향의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.2

Thymoma is associated with myasthenia gravis, Pure red cell aplasia, and autoimmune diseases such as autoimmune hemolytic anemia, aplastic anemia, and hypogammaglobulinemia. It's association with aplastic anemia is rare and aplastic anemia appearing after surgical removal of thymoma is especially rare. The authors hereby report a case of aplastic anemia occuring in a patient who was diagnosed with thymoma and myasthenia gravis and had the tumor surgically removed. The patient was treated with anti-thymocyte globulin, cyclosporin, and prednisolone, and showed partial remission with hematologic improvements after 12 months.

The Generalization and Application of Hadamard and CNOT Operators for n-dimensional Quantum States

배규찬 대구대학교 사범대학 부설 교육연구소 2007 敎育硏究 Vol.2 No.2

We generalize the Hadamard and CNOT operators for n-dimensional quantum states. Using these generalizations, we propose the generalized scheme of quantum teleportation and quantum secure direct communication (QSDC) for arbitrary n-dimensional system.

테니스 포핸드 스트로크의 포워드 스윙에서 multisegment 스윙과 single unit 스윙의 라켓 속도에 대한 기여도 비교에 관한 연구

임규찬,정철수 師範大學 體育硏究所 1993 서울大學校 體育硏究所論集 Vol.14 No.2

The purpose of this study was to compare the contribution to the speed of the racket of multisegment and single unit forehand stroke during forward swing in tennis. Each one skilled subject was filmed with three-dimensional cinematography, and after the film analysis procedure using the Direct Linear Transformation method, the factors contributing to the speed of the racket in each subject were obtained. The following conclusions were reached: 1. The typical difference of the preimpact speed of the racket between the multisegment swing and the single unit swing was not found, but each swing pattern was inclined to be different. 2. Concretely, the shoulder and elbow joint dominated the multisegment initial swing pattern, and the trunk rotation and elbow joint dominated the multisegment final swing pattern. Especially, the somersault component of the upperarm rotation dominated the upperarm initial swing pattern, and the twist component dominated the upperarm final swing pattern. 3. The shoulder and elbow joint dominated the single unit initial swing pattern, and during the intermediate phase the trunk rotation and elbow joint dominated the single unit swing pattern, finally the shoulder joint and the trunk rotation and the elbow joint dominated the single unit final swing pattern. Especially, the twist component of the upperarm rotation dominated the upperarm initial swing pattern, and the somersault component dominated the upperarm final swing pattern.

특수용 폴리머 콘크리트의 개발 및 역학적 특성

연규석,성찬용,민정기 강원대학교 석재복합신소재제품연구센터 1997 석재연 논문집 Vol.2 No.-

폴리머 콘크리트는 보통 시멘트 콘크리트보다 접착성, 방수성, 내구성 등이 우수하고 경화속도가 빠르며, 압축강도 및 휨강도가 월등히 큰 것으로 알려져 있다. 이에 본 연구는 충전제와 폴리머를 이용한 투수용 폴리머 콘크리트를 개발하여 이의 역학적 특성을 구명하기 위하여 실시되었으며, 결과를 요약하면 다음과 같다. 단위중량은 보통 시멘트 콘크리트에 비하여 작게 나타난 반면, 각 강도는 일부 배합비를 제외하고는 모두 크게 나타났으며, 정탄성계수가 작아서 변형이 크게 일어난다는 것을 알 수 있었고, 투수시험 결과 시간당 투수량이 최고 8.88ℓ/cm²/h로 나타나 투수성능이 양호하게 나타났을 뿐만 아니라, 이를 이용하여 제작된 투수관도 투수성능을 포함한 외압 강도도 크게 나타나, 기존의 투수관 보다 성능이 상당히 양호하다는 것을 알 수 있었다. 따라서, 투수용 폴리머 콘크리트는 농업분야는 물론 각종 건설분야에서 주택단지, 공장 등의 하수 및 오수관, 도로 등의 지하 배수관, 폐수처리용 오수관은 물론 농업용수 배수 및 송수관, 축산시설, 농업시설의 하수관 및 오수관, 농지배수용, 간척지 제염용 등 여러 분야에 이용 가능할 것으로 예상된다. The use of polymer concrete as on alternative to cement concrete products has been increasing because of its superior mechanical properties, chemical resistance, durability, strong adhesion and rapid curing, it is possible to reduce cross section of structure and unit weight of products when the polymer concrete is used in place of conventional materials. this study was performed to evaluate the mechanical properties of permeable polymer concrete using fillers and unsaturated polyester resin. In consequence of this study, the permeable polymer concrete was expected to show excellent performance and external pressure of the pipes made of permeable polymer concrete was more than that of normal poltland cement concrete. Therefore, permeable polymer concrete can be applied to roads, sidewalks, river embankment, drain pipes, conduits, retaining walls, yards, parking lots, plazas and interlocking blocks, etc.

建物斷熱材의 性能 및 效率的 施工方法에 관한 硏究

黃贊奎 釜山工業大學校 1995 論文集 Vol.37 No.-

This study is searching efficiency and character of heat insulating materials, consider heat insulting materials that should be examined and studied to be insulated for an efficient plan and execution with other materials in a point of present time because it is hard to be structural materials and facing materials independently. In using heat insulating materials in a building, the surface of building should be covered with heat insulating materials, and wall should make a execution, vapourproof layer should be set up indoors to prevent the measure of condensation. This study expect to develope better heat insulating, ventilation plan for supplying fresh air, improved heat insulating materials stronger and execution.

의료기사의 누적 외상성 증후군 증상에 관한 조사

박찬호,리갑수,이성수,안규동,이병국 순천향대학교 산업의학연구소 2001 순천향산업의학 Vol.7 No.1

The cumulative trauma disorder is a disease group of musculoskeletal systems developed by repeated work, which became greate concern in occupational health problem in Korea recently. Many paramedicals working in the department of Laboratory, Radiology, and Rehabilitation of the hospital have been engaged in the simple repetitive hard works causing cumulative trauma disorder. This is the study on the cumulative trauma disorder in those medical technicians. Total 285 (180 male, 105 female) medical technicians and office workers working in the hospital were surveyed with the self-administered questionnaires. They included the questions such as age, sex, marital status, education, height, weight, smoking and drinking history as a general characteristics and work department, kind of work, work duration, work conditions as a work characteristics. And also subjective symptoms related with the work in each region of body area were questioned. Among the work conditions, there were significant differences between medical technicians and office workers (e.g., high in medical technicians) in daily works lifting patients or heavy equipments, works moving continuously and rapidly, works with uncomfortable position, works keeping neck and upper arms in uneasy position. Complained rate of subjective symptoms was significantly higher in physical therapist and in the group of work duration over 10 years. The significant symptoms were pain, abnormal sensation, burning sensation. The significant factors affecting the subjective symptoms were female and work duration over 10 years for wrist area, female and current smoking for knee or ankle area, physical therapist, work duration between 6 and 9 years for lumbar area, female and radiologic technicians and work duration over 6 years for shoulder area. None was significant for neck area.

110m 허들의 구간별 운동학적 변인 분석

임규찬,정철수,이만기 師範大學 體育硏究所 1994 서울大學校 體育硏究所論集 Vol.15 No.2

This study was conducted to investigate the biomechanical characteristics of the interval running motions in elite hurdlers for the purpose of improving horizontal velocity. Here, interval running was divided into preparatory phase, hurdle phase, landing phase, and recovery phase in turn. The subjects were six males who were included in one current Korean national player. The interval running motions were filmed using four 16mm cameras. The motions were analyzed using the DLT (Direct Linear Transformation) method of three-dimensional cinematography. The conclusions were as follows; 1. In order to maintain the horizontal velocity, specially the spent time of hurdle phase should be decreased. 2. In order to maintain the horizontal velocity, the body c.o.g should be raised specially at the touch-down of hurdle phase and landing phase. 3. In order to maintain the horizontal velocity, specially the step length of landing phase and recovery phase should be increased. 4. In order to maintain the horizontal velocity, the active landing style should be performed as the sole of foot might claw the ground. 5. In other to delay the generation of the vertical velocity, knee flexion should be maintained until trail leg comes to the recovery phase. 6. In order to perform the hurdling motion efficiently, an optimal take-off angle should be kept up, and the body lean angles should be increased forward. 7. In order to decrease the airborne time, abduction and internal rotation of hip joint should be completed immediately before the clearance, and horizontal adduction should be advanced quickly immediately after the clearance.