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원태현,황기현,문경준,이용길 동의공업대학 2000 論文集 Vol.26 No.1
We propose an adaptive Tabu search method changing neighbor solution's range to be searched each iteration according to an objective function and design a PI controller using the proposed Tabu search. We apply it to a time-delay system to evaluate the usefulness of the proposed method. overshoot, rising time, and settling time.
p-Anisaldehyde가 조골세포 분화에 미치는 영향
김경민 ․ 이도원 ․ 김현준 ․ 김아랑 ․ 장원구 대구대학교 산업기술연구소 2018 産業技術硏究 Vol.29 No.2
p-Anisaldehyde is a natural fragrance extracted from Pimpinella anisum L., and used as a preservative. This study examined the effect of p-anisaldehyde on osteoblast differentiation. First, cytotoxicity tests were carried out after examining the concentrations that did not show toxicity to the cells. The expression of osteoblast differentiation marker gene was confirmed by RT-PCR and was not effective in the treatment with p-anisaldehyde alone. However, p-anisaldehyde decreased the expression levels of inhibitor of differentiation-1 (Id1), distalless related homeobox (Dlx5), and runt-related transcription factor 2 (Runx2), which are osteogenic differentiation marker genes, which are increased in osteogenic condition. alkaline phosphatase (ALP) activity was also confirmed by ALP staining that p-anisaldehyde reduced ALP activity. These results show that p-anisaldehyde is effective in reducing osteoblast differentiation.
논토양중 카드뮴 유효도와 수도의 흡수이행에 미치는 석회 및 Humic acid 사용효과
김민경,김원일,정구복,박광래,윤순강,엄기철 한국환경농학회 2004 한국환경농학회지 Vol.23 No.1
토양중 중금속이 식물에 흡수 및 이행되는 것을 경감시켜 여기에서 생산된 농산물의 안전성 향상을 위한 기초자료를 확보하고 논토양의 카드뮴 유효도와 흡수이행에 미치는 석회와 humic acid 처리 효과를 구명하기 위하여 실내경험과 포트실험을 수행하였다. 실내실험에서 공시토양에 2.5와 5.0 ton/ha의 석회와 1%와 2% humic acid를 처리한 후 토양중 가용성 카드뮴 함량 변화를 조사한 결과, 두 처리 모두 14일까지는 담수상태에서 처리효과로 인하여 가용성 카드뮴 함량이 감소하다가 그 이후에는 토양의 완충능에 의해 다시 증가하는 경향이었다. 이때, 토양의 가용성 카드뮴 함량은 토양 pH 및 양이온치환용량과 부의 상관이 있었다. 2.5 ton/ha의 석회와 1% 의 humic acid를 처리한 후 담수시켜 안정화된 다음 벼를 재배하여 조사한 결과, 석회와 humic acid 처리에 비해 분얼기와 수확기의 치화태 및 수용태 카드뮴 함량이 낮아졌으나, 분얼기에 비해 수확기에 토양중 이동이 어려운 산화물 및 탄산염태와 황화물 및 잔류태의 함량이 증가하였다. 식물에 흡수가 용이한 형태로 알려진 치환태와 수용태는 모두 토양 pH와 고도의 부의 상관이 있었다. 수확기의 줄기, 잎 및 현미 건물중은 석회 및 humic acide 처리구에서 대조구에 비해 모두 높았고, 특히 석회 처리구의 건물중이 현저하게 높았다. 석회 처리구에서 줄기와 잎의 카드뮴 함량은 각각 1.01과 0.37㎎/㎏으로 대조구와 비슷하였으나, 뿌리나 현미의 카드뮴 ?량은 각각 2.11과 0.09㎎/㎏으로 대조구에 비해 낮았다. 지상부와 뿌리의 카드뮴 함량은 humic acid 처리에 의해 현저히 낮아졌으며, 특히 현미로의 카드뮴 이행도 월등히 낮게 나타난다. This study was conducted to know the effect of lime and humic acid on cadmium availability and its uptake by plant grown in contaminated paddy soils with heavy metal. The treatment levels of lime were 2.5 and 5.0 ton/ha and that of humic acid were 1 and 2%. The contents of 0.1 N HCl extractable Cd were reduced with lime and humic acid and were negatively correlated with CEC as well as soil pH. The sequential extraction procedure was used to fractionate the heavy metals in soil into the designated from exchangeable (0.5 M KNO₃), water soluble (H₂O), organically bound (0.5 M NaOH), carbonate (0.05 M Na₂-EDTA) and sulfide/residual (4 M HNO₃). In soil amended with 2.5 ton/ha lime and 1% humic acid, chemical forms of Cd at tillering stage were predominant exchangeable+water soluble extractable Cd, whereas that at harvesting stage were predominant carbonate+sulfide/residual extractable Cd. The exchangeable forms of Cd in soil with lime and humic acid were negatively correlated with soil pH during the harvesting period. Total absorbed Cd of paddy rice tended to occur in the order of root > stem > leaf > brown rice. Cd con- tents of brown rice with lime and humic acid treatment were 0.09 and 0.08 mg/kg, respectively. That were lower than control, 0.20 ㎎/㎏. It could be that treatment of lime and humic acid in polluted soil by heavy metals would reduce the uptake of heavy metals by plants and be a temporary method of reclamation at the highly heavy metal contaminated soils.
유방의 과립구성 육종으로 재발한 급성 골수성 백혈병 1 례
박경배,서원석,신상만 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2
Granulocytic sarcoma is a malignant neoplasm composed of poorly differentiated cells of the myelogenous series. Granulocytic sarcoma are reported in 3.1-9.1% of patients with myelogenous leukemia and occur concomitantly, following or rarely antedating the onset of leukemia. Granulocytic sarcomas can occur at various sites of the body and frequently at multiple sites. Involvement of the breast is uncommon. We experienced a case of acute myelogenous leukemia. 12 months earlier, she was diagnosed as acute myelogenous leukemia(M2) and acheived complete remission with KSPHOG ANL regimen. The patient was treated with KSPHOG ANL regimen without radiation therapy. An 20th day, left breast lesion disappeared and complete remission was obtained.
복섬(Takifugu niphobles)자치어의 골격발달
한경호,오성현,서원일 한국어류학회 2003 韓國魚類學會誌 Vol.15 No.3
복섬의 부화 직 후 자어는 평균 전장 2.14 ㎜로 골격의 골화가 전혀 일어나지 않았으며, 부화 후 1일째 평균 전장 2.38 ㎜의 자어는 두개골에 복추골, 섭이와 관련하는 턱부분에 전상악골과 치골이 먼저 골화가 시작되었다. 부화 후 10일째 자어는 평균 전장 4.24㎜로, 두개골에 전이골과 익이골이 골화되었고, 내장골의 새개부에는 하새개골, 간새개골이 골화하여 새개부가 완성되고, 견대부의 후쇄골이 골화하기 시작하였다. 부화 후 28일째 후기자어의 평균 전장은 7.60㎜로 두개골에 상이골과 상후두골이 골화하여 두개골이 완성되었고, 척추골, 미골 및 담기골이 거의 동시에 골화되었다. 부화 후 35일째 치어는 평균 전장이 8.60㎜로 구개부에 후익상골이 골화하여 내장골이 골화가 완료되므로서, 모든 골격의 골화가 완성되었다. Eggs of Takifugu niphobles (Jordan et Snyder) collected on the shores of Dolsan, Yeosu, Korea, in July 1998, were artificially hatched and the larvae reared in the laboratory to investigate osteological development of larvae and juveniles. The newly hatched larvae attained a mean size of 2.38 ㎜ in total length (TL) and had an ossified dentary, premaxillary and clavicle at this stage. At 10 days after hatching, the larvae (mean 4.24 ㎜ in TL) had ossified prootic, pterotic, subopercle, and interopercle, and the postclavicle had begun to ossify. The ossification of the cranium, vertebrae, caudal skeleton and pterygiophore was complete in the larvae (mean 7.60 ㎜ in TL) at 28 days, and ossification of all bones was complete in the juveniles (mean 8.61 ㎜ in TL) at 35 days.
고경덕,이동원,정승현,신길조,이원철 동국대학교 한의학연구소 1997 東國韓醫學硏究所論文集 Vol.6 No.1
朱震亨은 金元四大家중 가장 후대의 인물로서 朱子學의 철학적 배경에 근거하여 劉河間, 張子和, 李??의 장점을 흡수하여 醫論을 펼쳤으므로, 金元四大家의 中風 內因論을 인식하는데 있어 그 의미가 크다. 朱震亨 中風論의 특징은 그가 거처한 純域的 特性에 근거하여 肥瘦人과 半身不遂의 左右에 따라 각각 治法을 달리하였으나, 中風 病因病理를 濕痰生熱로 보고 內因의 주요소로 痰을 중시하여 中風入方藥物은 治痰한다는 원칙에 기준하여 藥物을 사용하였다. 이러한 독특한 中風論은 후대 中風 內因論의 발전에 지대한 영향을 주었으므로, 이에 관한 연구는 中風 內因論 측면에서 韓醫學發展에 寄與할 것으로 恩慮된다. We inquired into the origins, pathologies, theraphies and prescriptions of Jungpung(中風) especially on the ground of Keokchiyeron(格致餘論)ㆍDangeosimbub(丹溪心法) written by JuJinHyoung(朱震亨) as modical blocks, from this study we could get that conclusions. 1. According to special feature of the theroies of JuJinHyoung's(朱震亨) Jungpung(中風) he thought pathologies of Jungpung(中風) as 「sub seong dam dam seong yeol yeol seong puns 濕疾痰痰生熱 熱生_風」through studying stress on regional characteristics and thought much of dam(疲) as one of major elements of internal causes. 2. He suggested chi-dam(治痰) in the first place in the treatment of Jungpung(中風) and emphasises the treatment using Succus Pyllostachyos(竹瀝), waterly extracted Rhizoma Zingiberis(鐘汁) in that they had the virtues of sodam-ganghwa(消痰降火), geo-gyeongrak(開經絡), haeng-heolgi(行血氣). 3. He treated differently whether a man in fat and thin, and have right or left hemiplegia, but he prescribed herb-medications on the principle that medications should have the virtues of chi-dam(治痰).
金元鎰,李允景,姜渭民 慶南大學校 附設 工業技術硏究所 1991 硏究論文集 Vol.9 No.-
本 硏究에서는 유리纖維 强化樹脂의 旋消時 각 切削 條件에 따른 超音波 振動切削과 常用切削時 나타나는 加工特性을 考察하기 위하여 眞圓度, 表面粗度을 中心으로 比較, 檢討한 結果 다음과 같은 結論을 얻을 수 있었다. 1. 眞圓度의 값은 切削條件 및 振幅에는 많은 影響을 받지 않고, 纖維角이 60˚인 경우 V=60m/min, f=0.08mm/rev, t=0.05mm일때 眞圓度 값이 10㎛로 가장 良好하였고, 纖維角이 90˚인 경우에는 振動切削에서는 19㎛, 常用切削에서는 37㎛로 가장 높은 값이 나타났으며, 振動切削이 常用切削 보다 약 2배 改善되었다. 2. 表面眺度는 纖維角이 60˚인 경우가 가장 良好하고, V=20m/min에서는 振動切削과 常用切削의 값은 거의 變化가 없으며 V=30m/min이상에서는 振動切削이 顯著하게 改善되었다. 3. 工具傾斜角은 眞圓度에는 많은 影響을 미치지 않지만 表面粗度는 0˚보다 6˚가 약간 改善됨을 알 수 있다. 4. 振動切削은 硏削에서 얻을 수 있는 加工精度를 旋削에서도 쉽게 얻을 수 있어 精密度와 生産性을 向上시키는 加工法이라 할 수 있다. In this paper, under different cutting condition on G.F.R.P, ultrasonic vibration cutting and the characteristics in conventional cutting have been studied. So the following conclusion centered on comparison, examination of roundess, surface roughness has been reached. 1. The value of surface roundess doesn't get much effect from amplitude as well as cutting conditions. With 60˚of fiber angle, v=60m/min, f=0.08mm/rev, t=0.05mm, the value of surface roundess, 10㎛, was the best. In case of 90˚, the highest value was 19㎛ in vibration cutting and 37㎛ in conventional cutting vibration cutting has improved about twice as high as conventional cutting. 2. In case the fiber angle was 60˚, surface roundess was little difference between vibeation and conventional cutting. Under v=30m/min and above, vibration cutting has remarkably improved. 3. Even if the tool rake angle doesn't affect the roundess, surface roughness has improved a little more at 6˚than at 0˚. 4. Vibration cutting helps to gain as lathe turing working precision as in grinding, Consequently, it's considered a good working method to improve precision and productivity.
설경원,박영구 全北大學校 1984 論文集 Vol.26 No.-
Grain growth in solid materials is simulated by LSW theory. First, the performance of this program is tested as follows. According to LSW theory, the size distribution becomes stationary time-independent one after some time from the beginning of growth whatever the initial size distribution is. So whether the simulated distribution will converge to the theoretical one is verified by CHI-SQUARE TEST using Gaussian distribution as initial distribution. After this verification, abnormal grain growth is simulated for 1st order reaction controlled system, 2nd order reaction controlled system, and for diffusion controlled system. In this simulation, large grains (about 3-5 times larger than the grain which has maximum size) are presented intentionally and the behavior of this system is observed. The result is that the abnormal grain growth can be occurred by initial size fluctuation.
超硬 切斷工具 刃先의 應力分布 解析에 관한 硏究 (I)
李允景,金元鎰 慶南大學校 附設 工業技術硏究所 1987 硏究論文集 Vol.5 No.-
旋削에 의한 超硬 切斷工具의 傾斜面 應力 變形率 分布에 대한 靜剛性 解析을 한 結果 다음과 같은 結論을 얻었다. 切斷加工에서 切削깊이 方向의 切削速度 變化는 切削力에 큰 영향을 주지 않으며, 切削條件에 의한 應力, 變形率 變化는 移送이 클수록 크고 接觸길이 0.3㎜ 정도에서 應力 값이 크게 減少하므로 칩핑 가능성이 높다. 應力 및 變形率의 變化幅이 큰 것은 切削에 있어서 摩擦의 狀態가 칩 傾斜面 接觸길이 部分에서 一定하지 않는다는 것을 알았다. In the turning, Analyses of the static deformation relating to the destributions of stress and strain on a rake face of cemented carbide parting tool have obtained results which are as follows, 1. In the parting work, the change of cutting speed relating to cutting depth and direction has been greatly uneffected cutting force. 2. As feed grows larger, the change of stress and strain under cutting conditions grows larger, and the value of stress decreases greatly in the near contect length of 0.3㎜. therefore, It is highly possible thet chipping occurs. 3. In the cutting, the changed value of strain and stress which is large have been not uniformed the state of friction in the near contect length of Chip-rake face.
원통 연삭에서 가공 능률 향상을 위한 연삭 저항의 측정에 관한 연구
김원일,이진,이윤경,왕덕현,이상복,이관철,문원길 경남대학교 공업기술연구소 2000 硏究論文集 Vol.18 No.-
본 연구에서는 원통 연삭 가공에서 가공 능률 향상을 위한 연삭 저항을 측정하고자 연삭 가공 중에 발생하는 연삭 저항의 추이를 확인하였고 다음과 같은 결과를 얻었다. 숫돌과 공작물간의 연삭 강성은 공작 속도의 증가에 따라 지지계의 강성이 높은 경우 증가하였고 절삭 깊이와 연삭 숫돌의 속도에는 연삭 강성이 감소하는 경향을 보였다. 또한 총합 강성은 공작 속도, 절삭 깊이 및 연삭 숫돌의 속도 증가에 따라 지지계의 강성이 높을 수록 증가하였다. 연삭기의 강성 변형과 가공 능률에 영향을 주는 값으로 연삭 강성비는 지지계의 강성이 높을 수록 감소하였다. In this study, the measurement of grinding resistance to improve grinding efficiency in cylindrical grinding was studied and the following conclusions could be obtained. Relation grinding wheel and workpiece, grinding stiffness increases according to increase of work speed for high machine stiffness and decreases depth of cut and grinding wheel speed. Also, resultant stiffness increases high machine stiffness according to increase work speed, depth of cut and grinding wheel speed. The values of the effect stiffness deflection in grinding machine, grinding stiffness ratio decrease according to high machine stiffness.