Blood Compatibility of Heparinized AAc , HEMA , and PEGMA - grafted Cellulose Film by Radiation Grafting

Kwon, O. H.,Nho, Y. C.,Lee, Y. M. 한국공업화학회 1999 응용화학 Vol.3 No.2

To improve surface blood compatibility on cellulose film for hemodialysis, acrylic acid (AAc ), 2-hydrolyethyl methacrylate (HEMA), and the three kinds of polyethylene glycol methacrylates (PEGMAs) were grafted onto the cellulose film surface by radiation grafting technique. And then heparin was introduced onto the grafted cellulose film surfaces. The grafting and heparinization were confirmed by Fourier transform infrared spectroscopy in the attenuated total reflectance mode (FTIR-ATR) and electron spectroscopy for chemical analysis (ESCA). The blood compatibility of heparin-introduced cellulose film surfaces after grafting was examined by the determination of platelet adhesion and thrombus formation. And the determination of platelet adhesion and thrombus formation was investigated by Imai and Nose method and field emission scanning electron microscopy (FE-SEM), respectively. The degree of platelet adhesion and thrombus formation on the sameples was lower than that of control cellulose.

Evaluating the effectiveness of the law banning handheld cellphone use while driving

Kwon, O.H.,Yoon, Y.,Jang, K. Elsevier 2014 Safety science Vol.70 No.-

Cellphone use while driving is one of the major concerns in traffic safety, and numerous researches found that cellphone use while driving can increase traffic collision risk. With growing popularity of cellphone use, many states in the United States enacted the law banning handheld cellphone use while driving in recent years. However, there is a debate on effectiveness of the law. In this study, we analyze the six-year collision data between 2006 and 2010 in the state of California to examine the timing of a significant change in the trend of cellphone related collisions. We adopt the turning point analysis technique without imposing a prior belief on whether or when such a change has occurred. Both the frequentist and Bayesian approaches are applied to four different groups, including the all cellphone collision group and three subgroups characterized by cellphone usage. The result shows that the turning points coincides with the timing of enforcement of the handheld law in California, except for the subgroup containing hands-free related collisions only. We applied the same method to two confounding factors including driving under influence and CD/radio use, and find that the turning points do not agree with the cellphone related collisions. Although a more comprehensive set of confounding factors needs to be considered to establish a causal relationship between the handheld law and cellphone related collisions, coincidence between the handheld law and the turning point suggests that the law should be considered as one of the primary factors in cellphone related collisions reduction.

지방정부의 개발 정책을 둘러싼 공공갈등 구조 분석 연구: 제주특별자치도 비자림로 확포장공사 사례를 중심으로

강권오 ( Kang¸ Kwon-oh ) 단국대학교 분쟁해결연구센터 2021 분쟁해결연구 Vol.19 No.2

본 연구는 지역 내에서 발생하는 공공갈등을 다각적인 관점에서 분석하고, 상황을 효과적으로 개선할 수 있는 대안을 검토하는데 그 목적이 있다. 이를 위하여 지방정부가 주도적으로 추진하는 정책 사례 중 비자림로 확포장공사 사례를 분석함으로써, 지역정책 추진 시 지방정부 차원에서 추진할 수 있는 대안을 제시하고자 하였다. 사례 분석을 위한 틀은 다자간의 갈등 해결을 목적으로 설계된 오스트롬의 제도분석틀(IAD Framework; Institutional Analysis and Development Framework)을 활용하였다. 분석 결과 비자림로 확포장공사 사례의 경우 제2공항 건설과 맞물리면서 이해관계집단이 복잡해지는 결과가 도출되었으며, 사회적 공감대 마련에 실패하면서 갈등이 심화되는 경향을 보였다. 또한 지역 주민들과의 소통이 원활하게 이루어지지 못하면서 지역주민들과의 신뢰가 하락하고 갈등이 장기화되는 결과가 도출되었다. 이러한 분석 결과를 토대로 하여 지역정책으로 인해 발생하는 공공갈등을 최소화하기 위한 대안을 제시하자면, 지방정부는 정책 시행의 전 과정에 대하여 객관적인 입장에서 투명하게 정보를 공유할 필요가 있으며, 또한 주민 신뢰 확보를 위해 사업 시행 과정에서 진행하는 주민 의견수렴 절차를 강화하여 추진할 필요가 있다. 또한 갈등을 예방하고, 발생 시 이에 따른 부작용을 최소화하 위해 공공갈등을 전문적으로 관리할 수 있는 전담 조직의 마련 등이 효과적인 대안이 될 수 있다. The purpose of this study is to analyze the public conflicts occurring within the region from a multi-pronged perspective and examine alternatives that can effectively improve the situation. To this end, it was intended to provide an alternative plan that can be implemented at the local government level when implementing regional policies by analyzing the case of expansion of Bijarim-ro among the policy cases led by local governments. The framework for case analysis utilizes Ostrom’s IAD framework (Institutional Analysis and Development Framework) designed for multilateral conflict resolution. According to the analysis, the case of Bijarim-ro expansion and pavement construction resulted in complicated interest groups as it coincided with the construction of a second airport, and conflicts tended to intensify as social consensus failed to be established. In addition, the lack of communication with local residents resulted in a decline in trust with local residents and a prolonged conflict. Based on this analysis, local governments need to share information transparently on the entire process of policy implementation, and strengthen the process of collecting opinions in the project implementation process to secure trust among residents. In addition, the establishment of a dedicated organization that can specialize in managing public conflicts can be an effective alternative to prevent conflicts and minimize side effects.

Safety and Effectiveness of Indwelling Percutaneous Drainage in Hospitalized Terminally Ill Cancer Patients with Recurrent Ascites

Kwonoh Park,Geon Woo Lee,Jae-Joon Kim,Sang-Bo Oh,So Yeon Oh,Eun-Ju Park,Jin Hyeok Kim,Joo Yeon Jang,Ung-Bae Jeon 이화여자대학교 의과학연구소 2020 EMJ (Ewha medical journal) Vol.43 No.2

Objectives: Terminally ill cancer patients in hospice palliative care unit are reluctant to undergo repetitive invasive procedures due to coagulopathies and poor performance or condition, while catheter management such as regular irrigation during hospitalization is easy. The purpose of this study was to investigate the safety and efficacy of indwelling intraperitoneal (IP) catheter in hospitalized terminally ill cancer patients with recurrent ascites. Methods: A retrospective review was conducted in patients who underwent IP catheter at the hospice palliative care unit of Pusan National University Yangsan Hospital between August 2016 and June 2018. All catheters were inserted by interventional radiologists with radiological guidance. The primary end-points were functional IP catheter maintenance rate, which is catheter maintained with patency for drainage until the intended time. Results: A total of 25 terminally ill cancer patients underwent IP catheters placements during the study period. All catheters were successfully inserted without major complications, but one patient had trivial bleeding and one other patient had temporary pain. The median time from admission to catheter insertion was 5 days (range, 1 to 49 days). Twenty-one catheters were maintained with function until the intended time, three cases were maintained without function, and the last one was removed early due to obstruction and pain. Finally, the functional IP maintenance rate was 84% (21/25) and the median functional catheter life span was 15 days (95% confidence interval, 10.8 to 17.2). Conclusion: Our study showed relatively favorable results for IP catheter maintenance and safety in hospitalized terminally ill cancer patients with malignant ascites.

Clinical Characteristics, Treatment Delivery, and Cisplatin Eligibility in Korean Patients Initially Diagnosed with Urothelial Carcinoma

Kwonoh Park,Jong Kil Nam,Bon Jin Koo,Hyun Jung Lee,Tae Un Kim,Hwaseong Ryu,Yun Jeong Hong,Seungsoo Lee,Dong Hoon Lee,Sung Woo Park 이화여자대학교 의과학연구소 2021 EMJ (Ewha medical journal) Vol.44 No.3

Objectives: The aim of this study was to examine the clinical presentation, treatment delivery, and cisplatin eligibility of Korean patients with urothelial carcinoma (UC) in a real-world setting. Methods: We performed a retrospective cohort study of patients initially diagnosed with UC from March 2013 to June 2018. Creatinine clearance >60 mL/min and Eastern Cooperative Oncology Group performance status (0–1) were adopted as cisplatin eligibility criteria. Results: This study included 557 eligible patients. Median age was 71.0 years (range, 33–94 years), and males were dominant (80%). Primary tumor sites were: upper genitourinary tract, 18%; bladder, 81%; and urethra, 0.4%. Initial disease status was non-muscle invasive bladder cancer (313, 56%), diffuse infiltrating non-muscle invasive bladder cancer (19, 3%), cTanyN0 upper tract UC (75, 13%), cT2-4N0 bladder UC (82, 15%), TanyN1-3 UC (36, 7%), or initially metastatic UC (32, 6%). At the time of analysis (June 2019), following treatments were delivered to 134 patients with localized UC: radical operation with or without perioperative treatment (89, 67%), definitive chemoradiation (7, 5%), and palliative surgery or supportive care only (36, 28%). In total, 89 patients had metastatic UC, including those with recurrent disease (n=57), and 34 (38%) of the 89 were eligible for cisplatin. Conclusion: Clinical presentations in East Asian UC patients were consistent with those of previous studies in other countries, except for a relatively high incidence of upper genitourinary tract. Our results can serve as a benchmark for further advances and future research for treatments of UC in East Asian patients.

요가 하는 남자들: 성인 남성의 요가 수련체계 형성 과정

권오정(KwonOh-jung) 한국체육학회 2016 한국체육학회지 Vol.55 No.5

본 연구는 근거이론 방법을 바탕으로 성인 남성의 요가 수련체계 형성 과정을 탐색할 목적으로 진행하였다. 이론적 표본추출(theoretical sampling)을 통해 요가에 1년 이상, 주 2회 이상 규칙적으로 참여하고 있는 성인 남성 8명을 선정하였으며, 심층면담을 통해 자료를 수집하였다. 자료분석은 근거이론 방법론(Strauss & Corbin, 1996)에 따라 개념을 도출하고 패러다임을 구성하였다. 연구결과, ‘요가 수련하기’가 중심현상으로 나타났으며, 중심현상에 대한 인과적 상황은 요가에 대한 기존 인식, 나에게 맞는 운동 탐색, 심리적 효과 기대로 나타났다. 맥락적 조건은 남성 외모관리 유행과 주요타자의 권유, 몸에 대한 위기감이였으며, 중심현상에 영향을 미치는 중재적 조건은 요가수련 방해요인과 촉진요인이었다. 상호작용 전략은 전문적인 관심, 온·오프라인 활동, 진지한 수련으로 나타났으며, 상호작용 전략에 따라 성인 남성의 요가 수련체계가 형성되었다. 즉, 성인 남성은 요가수련을 통해 신체 및 심리적 상태와 변화를 자각함으로써, 기존에 가지고 있던 요가에 대한 인식이 재형성되고 요가의 가치를 확신하게 되었다. This study was conducted to explore the formation process of yoga practicing system for male adults based on grounded theoretical approach. By theoretical sampling, 8 male adults were selected who have been practicing yoga more than twice a week, for over a year and data were collected through in-depth interviewing. In an analysis on the data, concepts were deduced and paradigm was structured based on grounded theoretical approach (Strauss & Corbin, 1996). According to study results, ‘practicing yoga’ has been seen as core phenomenon. It was found that traditional awareness on yoga, searching for the best physical activities, and psychological expectation effect caused the core phenomenon. Contextual conditions such as prevalence of appearance management among men and recommendations from others, concerns about the health have been found. With regard to intervening conditions, interrupting and precipitating factors for practicing yoga had effects on the core phenomenon. Interaction strategies have been observed such as professional interests, online and offline activities and practicing yoga in earnest, and according to these interaction strategies, yoga practicing system for male adults was formed. That is, male adults became aware of their physical and psychological conditions and changes through practicing yoga and this led them to reform their awareness on yoga and become assured of the value of yoga.

체육철학 : 양명학(陽明學)의 신체사상(身體思想)에 관한 연구(硏究)

권오륜(KwonOh-Ryun) 한국체육학회 1997 한국체육학회지 Vol.36 No.2

본 연구는 동양 철학의 대표적 사상의 하나로서 儒學의 한계파인 陽明學의 철학사상을 중심으로 양명학에 내재되어 있는 심신관과 양명학에 내재된 신체사상이 오늘날 체육학의 신체사상을 정립하는데 대안이 될 수 있는가를 살펴보았으며, 陽明學에서 함축된 身體思想을 먼저 知行合一의 사상에서 살펴보면, 良知를 통하여 세계의 주체로서 확립된 자아는 단순한 이론적 인식이나 사유의 주체일 뿐만 아니라 身體的·行動的·實踐的 주체이기도 하다. 그의 소위 知行은 良知와 實踐의 일관성 위에서 강구되어 결코 분리될 수 없으며, 實踐身體的 行爲을 良知의 판단작용으로 설명하고 良知의 공부를 行의 실천작용으로 간주하였다. 따라서 人間의 존재론적 가치로서의 身體는 서양철학사사에서 밝힌 二元論的관점을 초월하여 精神과의 관계를 떠난 身體性만으로도 가치가 있다.體用相卽의 측면에서 본 陽明學의 身體思想은 體=用=心=身의 등식으로 나타난다. 이러한 철학적 사고의 흐름은 기존의 心身二元論, 心身一元論, 心身一如, 心身統一體論, 心身綜合體論 등의 모든 心身關係論을 수용하고, 나아가 `心身`과 `身心`의 언어적 사용의 논란을 불식시키는 體用相卽的 心身觀`이라 규정한다. The philosophy of a human body in Yang-ming hsu¨eh could be found in Chi-hsing ho-i(知行合一) or the unity of knowledge and practice. The self, which was confirmed as the subject of the universe by means of Liang-chih(良知), was not only the subject of the universe by menas of Liang-chih, was not only the subject for perception and thinking but that of the body and the performance. Chi-hsing couldn’t be separated because it was constructed on the basis of the consistent relationship between Liang-chih and the practice. The practice [the movement of the body] was explained as the judging work of Liang-chih and the study of Liang-chih was explained as the practing work of Hsing(行).In T’i-yong-siang-chi(體用相卽) or the mutual relation between the original substance and the changable substance, the philosophy of a human body could be shown as a formula like T’i = Yong = Hsin = Hsan. That formula could include various philosophies of a human body such as dualism, monism, synthetism, unifism. From that standpoint, the linguistic usage of body-mind and mind-body could be taken away. Then, the human body in Yang-ming hsu¨eh (陽明學) was the thing interacting with the universe in a relation between the human being and the universe or the human being and the nature.For the future society in the 21st century, the physical education should find the the way solving today’s problems that resulted from the rapid scientific civilization such as the weakness of the body, the loss of humanity, the alination of human beings. So, the task of physical education was to reconstruct the meaning of a human body and to emphasize the importance of a human body. Then, the philosophy of a human body in Yang-ming hsu¨eh could be a proposal for the 21st society. Although there was the mainstream of the philosophy of physical education based on the Western philosophy, this study tried to find the existential Hsin-hsan kuan(心身觀) in the Oriental philosophy and to prepare the 21st century’s philosophy of a human body.

반려견 동반 운동 체험에 관한 근거이론적 접근

권오정(KwonOh-jung) 한국체육학회 2017 한국체육학회지 Vol.56 No.6

본 연구는 근거이론 방법론을 활용하여 반려견 동반 운동 체험을 탐색할 목적으로 진행하였다. 유의적 표집법을 통해 1년 이상, 주 3회 이상 규칙적으로 반려견과 운동하는 성인 남녀 10명을 선정하였으며, 심층면담을 통해 자료를 수집하였다. 자료분석은 근거이론 방법론에 따라 개념을 추출하고 패러다임 모형을 완성하였다. 연구결과, ‘함께 운동하기’가 중심현상으로 나타났으며, 인과적 상황은 ‘반려견에 대한 생각’과 ‘나의 운동 부족’으로 나타났다. 맥락적 조건은 ‘운동이 필요한 현실’과 ‘반려견 관리 필요’였으며, 중심현상에 영향을 미치는 중재적 조건은 ‘반려견 동반 운동 촉진요인’과 ‘반려견 동반 운동 방해요인’이었다. 상호작용 전략은 ‘반려견 동반 운동 전문성 확장’으로 나타났으며, 상호작용 전략에 따라 반려견 동반 운동 체계가 형성되었다. 즉, 참여자들은 반려견 동반 운동을 통해 자신의 건강뿐만 아니라 반려견의 건강을 관리하였으며, 상호작용적인 운동 동기유발과 효과를 체험하였다. This study aimed to investigate the experience of participating in exercise with companion dogs by using grounded theory methodology. 10 males and females who have participated in exercise with their companion dogs more than three times per week for over a year were selected by using purposive sampling, and data collected through in-depth interview with them. Concepts were extracted and a paradigm model was built by grounded theory methodology. As a result, ‘doing an exercise together’ was mainly observed in this study, and causal conditions were ‘thought of companion dogs’ and ‘a lack of exercise.’ Contextual conditions were ‘situation that exercise required’ and ‘the need for health care of companion dogs’ and intervening conditions that affect the main phenomenon were ‘facilitative factors on exercise with companion dogs’ and ‘obstructive factors on exercise with companion dogs.’ Interactive strategy was ‘enhancement of expertise in exercise of companion dogs’ and a system for exercise with companion dogs was formed according to the interactive strategy.

사회적 자본 관점에서의 지역정책 분류 모형 개발 연구: 제주특별자치도 사례를 중심으로

강권오 ( Kwonoh Kang ),황경수 ( Kyungsoo Hwang ) 사단법인 아시아문화학술원 2021 인문사회 21 Vol.12 No.1

본 연구의 목적은 정책 순응 확보를 위한 대안 마련에 앞서 사회적 자본의 관점에서 정책 유형을 분류하기 위한 모형을 개발하는 것이다. 이를 위해 본 연구에서는 사회적 자본의 구성요소와 Lowi의 정책 분류 모형을 활용하여 정책 사례 분류 모형을 개발하였다. 또한 이 모형에 따라 제주특별자치도 민선 1기부터 6기까지의 정책 사례를 적용함으로써 모형의 유용성을 검증하고자 하였다. 분석 결과 제주특별자치도의 주요 정책들의 경우 16개 중 4개 유형이 빈번하게 갈등이 발생하는 것으로 나타났으며, 이 유형의 정책들을 중점적으로 관리함으로써 지역 내 정책 순응 확보가 가능할 것으로 판단된다. 궁극적으로 지방정부와 주민 간 사회적 자본의 형성은 정책 순응을 위한 좋은 대안이 될 것인 바, 본 연구는 사회적 자본의 관점에서 정책 유형을 일반화할 수 있는 모형을 개발했다는데 그 의의가 있다. The purpose of this study is to develop a model for classifying policy types from the perspective of social capital prior to developing alternatives to securing policy conformance. To this end, in this work, we develop a policy case classification model by utilizing the components of social capital and Lowi’s policy classification model. According to this model, the Jeju Special Self-governing Province also sought to verify the usefulness of the model by applying policy cases from the 1st to 6th popular election. According to the analysis, four out of 16 major policies in Jeju Special Self-governing Province are frequently conflicted, and it is believed that it will be possible to secure regional policy compliance by focusing on this type of policies. Ultimately, the formation of social capital between local governments and residents will be a good alternative to policy compliance, meaning that this study has developed a model that can generalize policy types from the perspective of social capital.

p16 immunohistochemistry alone is a better prognosticator in tonsil cancer than human papillomavirus in situ hybridization with or without p16 immunohistochemistry

Park, Kwonoh,Cho, Kyung Ja,Lee, Miji,Yoon, Dok Hyun,Kim, Jiyoun,Kim, Sang Yoon,Nam, Soon Yuhl,Choi, Seung-Ho,Roh, Jonh-Lyel,Han, Myung Woul,Lee, Sang-Wook,Song, Si Yeol,Back, Jeong Hwan,Kim, Sung-Bae Informa Healthcare 2013 Acta oto-laryngologica Vol.133 No.3

<P><I>Conclusions:</I> p16 immunohistochemistry (IHC) status correlated with less exposure to smoking and/or alcohol in Korean patients with locally advanced tonsillar squamous cell carcinoma (TSCC), and was an independent prognostic factor for survival. <I>Objective:</I> TSCC is more likely to be human papillomavirus (HPV)-positive than other head and neck squamous cell carcinoma (HNSCC) subtypes. The objective of this study was to ascertain the HPV status of TSCC in Korean patients and to determine its relationship with clinical parameters and prognosis. <I>Methods:</I> The locally advanced TSCCs of 79 patients who were treated between 2000 and 2008 were tested by p16 IHC and HPV in situ hybridization (ISH) with a tissue microarray. <I>Results:</I> Sixty-three patients (80%) were positive for p16 IHC, while 54 (68%) were positive by HPV ISH. p16 IHC status correlated significantly with lower exposure to smoking and alcohol (<I>p</I> < 0.05) but did not correlate with T and N stage classification, histological differentiation, age, or gender. The p16-positive group had a significantly higher 5-year overall survival rate in comparison with the p16-negative group (78% vs 63%, hazard ratio (HR) = 0.347, 95% CI = 0.14, 95% C<I>p</I> = 0.025). p16 IHC was a favorable independent prognostic factor for overall survival, even after adjustment for age and T stage (HR = 0.283, 95% CI = 0.103, 95% <I>p</I> = 0.015).</P>